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ClinicalTrials.gov public records Last synced Nov 15, 2026, 7:00 AM EST

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Showing 865–888 of 2,615 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Sleep-Wake Disorders Clear all

Conditions: Sleep Disorders, Cerebrovascular Disorders, Cardiovascular Disease, Neurologic Disorders, Mood Disorders
Interventions: Not listed
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 30 Years to 95 Years
Enrollment: 1,545 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 1999 – 2031
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Poor Sleep Quality, Leg Cramps, Nocturnal, Melatonin, Magnesium, Muscle Cramps
Interventions: Magnesium and melatonin based multi-ingredient dietary supplementation, Placebo; Dietary Supplement · Other
Lead sponsor: StudySetGo; Network
Eligibility: 40 Years to 75 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 7
States / cities: Birmingham, Alabama • Little Rock, Arkansas • Palm Beach Gardens, Florida + 4 more

Conditions: Stroke Patients, CPAP, OSA - Obstructive Sleep Apnea
Interventions: CPAP device, CPAP technical support, Phone follow-up for adherence feedback and self-management skills, myAir, Tailored messages, Written Materials, Motivational Enhancement Therapy (MET); Device · Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 2
States / cities: Downey, California • Seattle, Washington

Conditions: Insomnia Chronic, Osteoarthritis, Pain, Chronic
Interventions: Audiovisual Stimulation; Device
Lead sponsor: University of Washington; Other
Eligibility: 60 Years and older
Enrollment: 72 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Depression
Interventions: Sleep Education Therapy, Cognitve Behavioral Therapy for Insomnia; Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 60 Years and older
Enrollment: 308 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2018
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Sleep Apnea, Obstructive
Interventions: Adherence program; Behavioral
Lead sponsor: Fisher and Paykel Healthcare; Industry
Eligibility: 18 Years and older
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015
U.S. locations: 3
States / cities: Huntsville, Alabama • Belleville, Illinois • Columbia, South Carolina

Conditions: Headache Disorders, Migraine Disorders, Insomnia
Interventions: Intervention for Sleep and Pain in Youth; Behavioral
Lead sponsor: Seattle Children's Hospital; Other
Eligibility: 11 Years to 17 Years
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Sleep Apnea, Obstructive, Sleep Apnea, Central
Interventions: Smart CO2; Device
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years to 75 Years
Enrollment: 13 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Insomnia
Interventions: V117957 tablets, Placebo; Drug
Lead sponsor: Imbrium Therapeutics; Industry
Eligibility: 18 Years to 64 Years
Enrollment: 114 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 17
States / cities: Glendale, California • Riverside, California • San Diego, California + 13 more

Conditions: Diabetes
Interventions: Sleep extension, Fixed Sleep Duration; Behavioral
Lead sponsor: University of Arizona; Other
Eligibility: 10 Years to 16 Years
Enrollment: 114 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Tucson, Arizona

Conditions: Sleep Deprivation, Delirium
Interventions: Sleep/Wake Protocol; Behavioral
Lead sponsor: University of Utah; Other
Eligibility: 18 Years and older
Enrollment: 685 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Obstructive Sleep Apnea (OSA)
Interventions: Sleep Navigator; Behavioral
Lead sponsor: Uniformed Services University of the Health Sciences; Federal
Eligibility: 18 Years to 64 Years
Enrollment: 160 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 2
States / cities: Bethesda, Maryland

Conditions: Insomnia, End Stage Renal Disease
Interventions: Cognitive Behavioral Therapy for Insomnia, Trazodone, Placebo; Behavioral · Drug
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 126 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Insomnia
Interventions: Cognitive Behavioral Therapy for Insomnia; Behavioral
Lead sponsor: University of California, Davis; Other
Eligibility: 18 Years and older · Female only
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Sleep Apnea Syndromes
Interventions: Video Teleconferencing Care, Usual Care; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: San Diego, California

Conditions: Narcolepsy
Interventions: JZP-258; Drug
Lead sponsor: Jazz Pharmaceuticals; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 62 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 28
States / cities: Alabaster, Alabama • Birmingham, Alabama • Los Angeles, California + 22 more

Conditions: Chronic Insomnia
Interventions: Internet-based Cognitive Behavioral Therapy for Insomnia; Behavioral
Lead sponsor: VA Connecticut Healthcare System; Federal
Eligibility: 18 Years and older
Enrollment: 51 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: West Haven, Connecticut

Conditions: Insomnia, Primary Insomnia, Psychophysiologic Insomnia
Interventions: Zolpidem, Sugar Pill; Drug
Lead sponsor: University of Rochester; Other
Eligibility: 25 Years to 55 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2008
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Insomnia, GERD
Interventions: Rabeprazole; Drug
Lead sponsor: University of North Carolina; Other
Eligibility: 18 Years to 75 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2006
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Insomnia Chronic, Pain, Chronic
Interventions: Virtual Reality Mediated Relaxation; Device
Lead sponsor: University of Missouri-Columbia; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2026
U.S. locations: 1
States / cities: Columbia, Missouri

Conditions: Obstructive Sleep Apnea
Interventions: continuous negative external pressure; Device
Lead sponsor: Sommetrics, Inc.; Industry
Eligibility: 22 Years to 70 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Alameda, California

Conditions: PTSD, Anxiety, Post Traumatic
Interventions: Xyrem; Drug
Lead sponsor: State University of New York - Upstate Medical University; Other
Eligibility: 18 Years to 64 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2006
U.S. locations: 1
States / cities: Syracuse, New York

Conditions: Sleep Apnea, Obstructive, Obesity
Interventions: Propofol Alone, Propofol+Benzo/Opioids; Drug
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Insomnia
Interventions: Cognitive Behavioral Therapy for Insomnia (CBTI), Perinatal-enhanced Behavioral Therapy for Insomnia, Attention Control; Behavioral
Lead sponsor: Henry Ford Health System; Other
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 64 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Novi, Michigan

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Epidemiology of Sleep-Disordered Breathing in Adults

The Effect of a Daily Magnesium and Melatonin Supplement on Sleep Quality in People With Nighttime Leg Cramps

Stroke and CPAP Outcome Study 3 Randomized Controlled Trial

Audio-visual Stimulation: Sleep Dose Response

Promoting Sleep and Healthy Aging Research Study (PRO-SHARE)

Positive Airway Pressure Program

Intervention for Sleep and Pain in Youth

Variable Dead Space Rebreathing Device to Treat Sleep Apnea

Safety, Tolerability and Efficacy Study of V117957 in Subjects With Insomnia Associated With Alcohol Cessation

Sleep Intervention for Youth With Type 1 Diabetes

Sleep/Wake Protocol Implementation to Improve Sleep Quality in the ICU

Telehealth for Sleep Apnea: Effectiveness, Implementation, and Cost in the Military Health System

Short and Long-Term Effectiveness of Existing Insomnia Therapies for Patients Undergoing Hemodialysis

Feasibility of Internet Group CBT-I for Gyn Oncology Patients

Using Telemedicine to Improve Veteran Sleep Apnea Care

An Interventional Safety Switch Study (Segue Study) of XYWAV in Narcolepsy

Piloting an Internet-based Therapy for Insomnia in a Population of Veterans With Substance Use Disorders

Long Term Treatment With Zolpidem: Nightly and Intermittent Dosing

Sleep Disorders and Gastroesophageal Reflux Disease (GERD)

Sleep Intervention for Chronic Insomnia Using Virtual Reality Pilot Study

Home Study of Subjects Who Have Completed a Previous Continuous Negative External Pressure (cNEP) Clinical Trial

Xyrem for Treatment Refractory Insomnia Due to PTSD

Propofol vs Propofol + Benzo/Opiates in High Risk Group

Improving Negative Stressful Perseverations in Insomnia to Revitalize Expectant Moms