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ClinicalTrials.gov public records Last synced Nov 15, 2026, 1:09 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1273–1296 of 2,615 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Sleep-Wake Disorders Clear all

Conditions: Burnout, Insomnia, Well Being
Interventions: Transcendental Meditation Technique; Behavioral
Lead sponsor: The Center for Clinical and Cosmetic Research; Other
Eligibility: 18 Years and older
Enrollment: 130 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Aventura, Florida

Conditions: Sleep Apnea, Obstructive
Interventions: Remifentanil, Cold pain threshold and tolerance, Heat pain threshold and tolerance, Polysomnography; Drug · Procedure · Device
Lead sponsor: Stanford University; Other
Eligibility: 18 Years to 55 Years · Male only
Enrollment: 56 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Stanford, California

Conditions: Insomnia, Alcohol; Harmful Use
Interventions: Cognitive Behavioral Therapy for Insomnia, Sleep Hygeine; Behavioral
Lead sponsor: University of Missouri-Columbia; Other
Eligibility: 18 Years and older
Enrollment: 71 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Columbia, Missouri

Conditions: Alzheimer Disease, Dementia, Sleep Disorder, Sleep Disturbance
Interventions: LOCK Sleep Program, No intervention (control period/baseline data collection); Behavioral · Other
Lead sponsor: University of Alabama, Tuscaloosa; Other
Eligibility: 50 Years and older
Enrollment: 456 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 3
States / cities: Lakewood, Colorado • Murfreesboro, Tennessee • San Marcos, Texas

Conditions: Dementia, Sleep Apnea
Interventions: Continuous positive airway pressure; Device
Lead sponsor: University of California, San Diego; Other
Eligibility: 50 Years to 85 Years
Enrollment: 61 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2000 – 2006
U.S. locations: 1
States / cities: San Diego, California

Conditions: Insomnia Disorder
Interventions: Cognitive Behavioral Therapy for Insomnia (CBT-I), Passive Body Heating (PBH); Behavioral · Device
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Primary Insomnia
Interventions: Cereve Sleep System at 30 degrees C, Cereve Sleep System at 14-16 degrees C; Device
Lead sponsor: Cereve, Inc.; Industry
Eligibility: 22 Years and older
Enrollment: 144 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013
U.S. locations: 9
States / cities: Little Rock, Arkansas • Miami, Florida • Pembroke Pines, Florida + 5 more

Conditions: Obstructive Sleep Apnea
Interventions: SmartFlex, Standard; Device
Lead sponsor: DeVilbiss Healthcare LLC; Industry
Eligibility: 18 Years and older
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 2
States / cities: Dallas, Texas • San Antonio, Texas

Conditions: Sleep Initiation and Maintenance Disorders
Interventions: Program A, Program B; Other
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 55 Years and older
Enrollment: 188 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2023
U.S. locations: 2
States / cities: Los Angeles, California

Conditions: Sleep Initiation and Maintenance Disorders
Interventions: Abbreviated cognitive behavioral therapy, Sleep education/sleep hygiene; Behavioral
Lead sponsor: University of Alabama, Tuscaloosa; Other
Eligibility: 18 Years to 24 Years
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Tuscaloosa, Alabama

Conditions: Insomnia, Metabolic Health, Menopause
Interventions: Suvorexant, Placebo; Drug
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 40 Years to 65 Years · Female only
Enrollment: 31 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Lipodystrophy
Interventions: Tesamorelin (Egrifta); Drug
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 75 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2012
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Obstructive Sleep Apnea
Interventions: Inspiratory muscle strength training, Placebo; Other
Lead sponsor: University of Arizona; Other
Eligibility: 30 Years to 75 Years
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Tucson, Arizona

Conditions: Sleep Apnea, Obstructive
Interventions: Not listed
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Timeline: 2022 – 2028
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Narcolepsy
Interventions: Transition from Xyrem to Xywav; Drug
Lead sponsor: Jazz Pharmaceuticals; Industry
Eligibility: 18 Years and older
Enrollment: 110 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Obstructive Sleep Apnea
Interventions: Grass S88 Muscle Stimulator; Device
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2028
U.S. locations: 1
States / cities: Nashvile, Tennessee

Conditions: Sleep Apnea, Obstructive
Interventions: Weight-loss (bariatric) surgery; Procedure
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years to 65 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2017
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Low Back Pain, Recurrent
Interventions: Hyp-8, Hyp-2 w recordings, Hyp-8 w recordings, BIO; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 161 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2018
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Breast Cancer, Hot Flashes, Sleep Disorders
Interventions: venlafaxine, zolpidem tartrate, management of therapy complications; Drug · Procedure
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 65 Years · Female only
Enrollment: 119 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2010
U.S. locations: 2
States / cities: Boston, Massachusetts

Conditions: Autism, Sleep Disturbance
Interventions: Power Down bedtime manipulation; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 6 Years to 10 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Insomnia, Sleep Disorder, Dyssomnia
Interventions: propofol injectable emulsion; Drug
Lead sponsor: Life Extension Foundation Inc.; Other
Eligibility: 18 Years to 65 Years
Enrollment: 2 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Fort Lauderdale, Florida

Conditions: Obstructive Sleep Apnea
Interventions: KPAP, APAP; Device
Lead sponsor: SleepRes Inc.; Industry
Eligibility: 20 Years to 80 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Murfreesboro, Tennessee

Conditions: Restless Legs Syndrome
Interventions: Rotigotine 1 milligram/24 hours, Rotigotine 2 milligram/24 hours, Placebo; Drug
Lead sponsor: UCB Biopharma SRL; Industry
Eligibility: 13 Years to 17 Years
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Culver City, California

Conditions: Cardiometabolic Health
Interventions: Not listed
Lead sponsor: Arkansas Children's Hospital Research Institute; Other
Eligibility: 13 Years to 21 Years
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 2
States / cities: Little Rock, Arkansas

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Improving the Mental Health and Well Being of Healthcare Providers Through the Transcendental Meditation Technique

Study of Pain Processing in Subjects Suffering From Obstructive Sleep Apnea

The Insomnia Treatment and Problems Study for Veterans

Enhancing Sleep Quality for Nursing Home Residents With Dementia - R33 Phase

Effect of Treating Sleep Apnea on Cognition in Patients With Dementia

Optimizing an Integrated Mind and Body Treatment for Insomnia: The SLEEPS Study 2

Comparison of Two Temperatures to Treat Insomnia

DeVilbiss AutoAdjust With SmartFlex Comparative Study

Sleep Without Insomnia or The Use of Chronic Hypnotics

Self-Help Video for Insomnia in College Students

Treating Insomnia and Improving Metabolic Health in Midlife Women With Insomnia

Egrifta Replacement and Sleep Disordered Breathing

Inspiratory Muscle Strength Training for Sleep-related Breathing Disorders

Predicting Outcomes in Hypoglossal Nerve Stimulation Therapy With Stimulated Upper Airway Mechanics

A Patient-Centric, Prospective, Observational, Non-Interventional Switch Study of XYWAV in Narcolepsy

Muscle Stimulation During DISE

Assessment of Sleep Apnea and Its Causes Before and After Weight Loss Surgery

Treatment of Veterans With Chronic Low Back Pain

Venlafaxine With or Without Zolpidem in Treating Hot Flashes and Associated Sleep Disorders in Women With Breast Cancer OR at High Risk for Developing Breast Cancer

The Power Down Pilot Study: A Novel Bedtime Manipulation Protocol

Efficacy and Safety Study of Propofol Infusion for Refractory Chronic Primary Insomnia

KPAP Adherence Crossover Study

A Study of Rotigotine Patch in Adolescent Subjects With Restless Legs Syndrome of Unknown Cause

Trajectory Study: Predicting Cardiometabolic Health in Adolescents and Young Adults Based on Childhood Fitness, Sleep, and Diet