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ClinicalTrials.gov public records Last synced Nov 15, 2026, 1:55 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1369–1392 of 2,615 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Sleep-Wake Disorders Clear all

Conditions: Sleep Apnea, Obstructive, Craniofacial Abnormalities, Pediatric Disorder
Interventions: Personalized continuous positive airway pressure (CPAP) mask; Device
Lead sponsor: Glenn Green; Other
Eligibility: 1 Year to 18 Years
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Restless Legs Syndrome, Neuropathic Pain
Interventions: Dual-energy X-ray absorptiometry Scan, Laboratory Measurements, Blood Flow Measurement, Continuous Blood Pressure, Partial pressure of oxygen, Microneurography, Anthropometric Measurements, John Hopkins Restless Legs Severity Scale, Continuous Blood Pressure Diary; Diagnostic Test · Other · Behavioral
Lead sponsor: Marshall Holland; Other
Eligibility: 18 Years to 85 Years
Enrollment: 15 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Sickle Cell Disease, Sickle Cell Anemia, Insomnia, Sleeplessness, Transient Insomnia, Nonorganic Insomnia, Chronic Insomnia
Interventions: ACT Intervention, Waitlist; Behavioral
Lead sponsor: National Cancer Institute (NCI); NIH
Eligibility: 18 Years to 55 Years
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Primary Insomnia
Interventions: Cognitive Behavior Therapy-Insomnia, Focus of Attention, Combined-CBT-I and FOA Group, Sleep Hygiene; Behavioral
Lead sponsor: Pacific Institute of Medical Sciences; Other
Eligibility: 18 Years to 72 Years
Enrollment: 160 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2022
U.S. locations: 2
States / cities: Bothell, Washington

Conditions: Lifestyle Factors, Overweight and Obesity, Insulin Sensitivity, Eating Habit, Sleep Hygiene, Type 2 Diabetes, Sleep, Sleep Deprivation, Insufficient Sleep Syndrome
Interventions: Sleep Extension Intervention; Behavioral
Lead sponsor: University of Utah; Other
Eligibility: 18 Years to 45 Years
Enrollment: 70 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Sleep Apnea, Atrial Fibrillation
Interventions: Adaptive Servo-Ventilation, Usual Care; Device · Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: HIV Infections, Insomnia
Interventions: Doxepin, Temazepam, Placebo; Drug
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 69 Years
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Insomnia, Cancer
Interventions: Acupuncture, Cognitive Behavior Therapy; Other
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 160 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 2
States / cities: New York, New York • Philadelphia, Pennsylvania

Conditions: Internalizing Mental Health Symptoms, Sleep Problems
Interventions: Sleep Extension, Healthy Living Psychoeducation; Behavioral
Lead sponsor: University of Illinois Chicago; Other
Eligibility: 18 Years to 30 Years
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Sleep Disordered Breathing, Able Bodied
Interventions: Trazodone + positive airway pressure (PAP) therapy, Oxygen + positive airway pressure (PAP) therapy; Drug
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Pregnancy Related, Sleep Disordered Breathing, Obesity
Interventions: Not listed
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 20 Years to 39 Years · Female only
Enrollment: 19 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Alcohol Use Disorder, Insomnia
Interventions: Daridorexant, Placebo, Brief Counseling, MEMS and Medication Accounting, Contingency Management for Medication Adherence; Drug · Behavioral · Device
Lead sponsor: Sterling McPherson; Other
Eligibility: 18 Years and older
Enrollment: 205 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 1
States / cities: Spokane, Washington

Conditions: Sleep Disorders
Interventions: Zolpidem, Escitalopram, Placebo; Drug
Lead sponsor: University of Pittsburgh; Other
Eligibility: 20 Years to 50 Years
Enrollment: 69 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2002 – 2008
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Restless Legs Syndrome
Interventions: Investigational Noninvasive Neuromodulation Device; Device
Lead sponsor: Noctrix Health, Inc.; Industry
Eligibility: 21 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025
U.S. locations: 1
States / cities: Pleasanton, California

Conditions: Sleep, Sleep Disturbance, Sleep Disorder
Interventions: Radicle Rest Placebo Control Form 1, Radicle Rest Active Study Product 1.1 Usage, Radicle Rest Placebo Control Form 2, Radicle Rest Active Study Product 2.1 Usage, Radicle Rest Placebo Control 4.1.0, Radicle Rest Active Study Product 4.1.1 Usage; Dietary Supplement
Lead sponsor: Radicle Science; Industry
Eligibility: 21 Years to 105 Years
Enrollment: 1,646 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Del Mar, California

Conditions: Hypersomnia, Primary Hypersomnia, Idiopathic Hypersomnia, Narcolepsy Without Cataplexy
Interventions: Flumazenil; Drug
Lead sponsor: Lynn Marie Trotti; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Insomnia
Interventions: 20 mg VEC-162, 50 mg VEC-162, 100 mg VEC-162, Placebo; Drug
Lead sponsor: Vanda Pharmaceuticals; Industry
Eligibility: 21 Years to 50 Years
Enrollment: 411 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006
U.S. locations: 19
States / cities: Birmingham, Alabama • Phoenix, Arizona • San Diego, California + 16 more

Conditions: Sleep Apnea, Adverse Event
Interventions: Questionaire; Other
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years and older
Enrollment: 350 participants
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Weston, Florida

Conditions: Sleep Quality
Interventions: SLEEP-E Dyads Intervention; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 102 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Decatur, Georgia

Conditions: Postoperative Pain, Acute, Postoperative Depression, Anxiety, Sleep Disturbance, Malignant Female Reproductive System Neoplasm
Interventions: eHealth Mindful Movement and Breathing, Life Impacts Reflection, PROMIS Questionnaires; Other
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older · Female only
Enrollment: 160 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2026
U.S. locations: 2
States / cities: Charlotte, North Carolina • Winston-Salem, North Carolina

Conditions: Sleep Apnea, Obstructive, Tonsillitis
Interventions: ETT with non modified retractor, LMA with modified retractor; Procedure · Other
Lead sponsor: Eastern Virginia Medical School; Other
Eligibility: 2 Years to 16 Years
Enrollment: 81 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2022
U.S. locations: 1
States / cities: Norfolk, Virginia

Conditions: Premature Birth, Asthma in Children, Sleep-Disordered Breathing, Neurodevelopmental Disorders
Interventions: Not listed
Lead sponsor: Ann & Robert H Lurie Children's Hospital of Chicago; Other
Eligibility: 30 Weeks to 83 Months
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Cancer Survivorship, Insomnia
Interventions: Survivorship Sleep Program with Individual Delivery + No Booster Sessions, Survivorship Sleep Program with Group Delivery + No Booster Sessions, Survivorship Sleep Program with Individual Delivery + 3 Booster Sessions, Survivorship Sleep Program with Group Delivery + 3 Booster Sessions; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Insomnia
Interventions: Partner-Assisted Cognitive Behavioral Therapy for Insomnia; Behavioral
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: San Diego, California

Search by objective public record fields.

3D-Printed CPAP Masks for Children With Obstructive Sleep Apnea

Spinal Cord Stimulation for Restless Legs Syndrome

Feasibility and Preliminary Efficacy of Acceptance and Commitment Therapy (ACT) for Sleep Disturbances in Adults With Sickle Cell Disease (SCD)

Comparison of Efficacy of Behavioral Approaches for Treatment of Insomnia

Effect of Sleep Extension on Ceramides in People With Overweight and Obesity

Atrial Fibrillation Recurrence in Sleep Apnea

The Treatment of Insomnia in Patients With HIV Disease

Choosing Options for Insomnia in Cancer Effectively (CHOICE): A Comparative Effectiveness Trial of Acupuncture and Cognitive Behavior Therapy

Pilot Sleep Extension and Mood

Central Apnea in Heart Failure: Physiological Mechanisms to Inform Treatment

The Sleep in Pregnancy Study

Daridorexant for People With Insomnia and Alcohol Use Disorder Study

Characteristics of Sleep Patterns in Young Adults With and Without Insomnia

Response to an Investigational Device in Patients With Restless Legs Syndrome

Radicle Rest 24: A Study of Health and Wellness Products on Sleep and Related Health Outcomes

Flumazenil for the Treatment of Primary Hypersomnia

VEC-162 Study in Healthy Adult Volunteers in a Model of Insomnia

Can Sleep Apnea Screening Questionnaire Predict Adverse Events in Endoscopic Studies

Improving Sleep in Veterans and Their CGs

REmotely-delivered Supportive Programs for Improving Surgical Pain and disTrEss

Laryngeal Mask Airway in Pediatric Adenotonsillectomy

Post-Vent, the Sequelae: Personalized Prognostic Modeling for Consequences of Neonatal Intermittent Hypoxemia in Preterm Infants at Pre-School Age

Innovating CBT-I for Cancer Survivors: An Optimization Trial

Researching Effective Sleep Treatments (Project REST)