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ClinicalTrials.gov public records Last synced Nov 15, 2026, 2:40 PM EST

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Showing 1441–1464 of 2,615 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Sleep-Wake Disorders Clear all
Completed Phase 1 Interventional Results available

Is Obstructive Sleep Apnea Important in the Development of Alzheimer's Disease?

NCT05094271
View directory record Official record
Conditions
OSA, Sleep Apnea, Obstructive Sleep Apnea, Alzheimer Disease
Interventions
Supplemental Oxygen, Continuous Positive Airway Pressure Machine, Room Air
Other · Device
Lead sponsor
University of California, San Diego
Other
Eligibility
65 Years to 85 Years
Enrollment
182 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Nov 15, 2026, 2:40 PM EST
Completed Not applicable Interventional Results available

Feasibility of Bright Light Therapy on Fatigue, Sleep and Circadian Activity Rhythms in Lung Cancer Survivors

NCT02954809
View directory record Official record
Conditions
Fatigue, Sleep Disturbance, Circadian Dysregulation
Interventions
Morning bright light therapy, Dim light
Device
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated May 1, 2025 · Synced Nov 15, 2026, 2:40 PM EST
Withdrawn Phase 4 Interventional

Butrans for Treatment of Restless Legs Syndrome

NCT02138357
View directory record Official record
Conditions
Restless Legs Syndrome
Interventions
buprenorphine transdermal delivery system (BTDS), Placebo for BTDS patch
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
25 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 25, 2023 · Synced Nov 15, 2026, 2:40 PM EST
Completed Phase 3 Interventional

Study of Eszopiclone Compared to Placebo on Daytime Function in Subjects With Insomnia Related to Rheumatoid Arthritis

NCT00367965
View directory record Official record
Conditions
Insomnia, Arthritis, Rheumatoid
Interventions
Eszopiclone, placebo
Drug
Lead sponsor
Sumitomo Pharma America, Inc.
Industry
Eligibility
25 Years to 64 Years
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004
U.S. locations
38
States / cities
Huntsville, Alabama • Tucson, Arizona • Santa Maria, California + 35 more
Source: ClinicalTrials.gov public record
Updated Feb 22, 2012 · Synced Nov 15, 2026, 2:40 PM EST
Completed Not applicable Interventional Results available

High-resolution, Relational, Resonance-based, Electroencephalic Mirroring (HIRREM) to Relieve Insomnia

NCT01971567
View directory record Official record
Conditions
Insomnia
Interventions
HIRREM
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 10, 2018 · Synced Nov 15, 2026, 2:40 PM EST
Completed Phase 3 Interventional Results available

Obstructive Sleep Apnea (OSA), Sleepiness, and Activity in Diabetes Management

NCT00801892
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Diabetes Mellitus, Type 2
Interventions
Continuous Positive Airway Pressure (CPAP), Sham- Continuous Positive Airway Pressure (Sham-CPAP)
Device
Lead sponsor
Eileen R. Chasens
Other
Eligibility
40 Years to 65 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 8, 2017 · Synced Nov 15, 2026, 2:40 PM EST
Completed Not applicable Interventional Accepts healthy volunteers

Safety Monitoring for a Novel 3D Printed Mandibular Advancement Device

NCT05018234
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Noval Oral Appliance
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 25, 2022 · Synced Nov 15, 2026, 2:40 PM EST
Completed Not applicable Interventional Accepts healthy volunteers

Diagnosis of Sleep-Related Respiratory Disorders in Patients With Narcotic Medications

NCT03670914
View directory record Official record
Conditions
Narcotic Use, Central Sleep Apnea
Interventions
WatchPAT 200
Diagnostic Test
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Fontana, California
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Nov 15, 2026, 2:40 PM EST
Completed Phase 2 Interventional Results available

The Sleep, Liver Evaluation and Effective Pressure Study

NCT01482065
View directory record Official record
Conditions
Non Alcoholic Fatty Liver Disease, Obstructive Sleep Apnea
Interventions
CPAP (ResMed S9 autoset CPAP)
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 4, 2017 · Synced Nov 15, 2026, 2:40 PM EST
Completed No phase listed Observational

Sleep Disordered Breathing and Alzheimer's Disease Biomarkers in Normal Aging and Mild Cognitive Impairment

NCT03912571
View directory record Official record
Conditions
Sleep Disorder
Interventions
Structural 3T MRI, MRI Based Perfusion Imaging, VR-CO2 MRI Scans
Diagnostic Test
Lead sponsor
NYU Langone Health
Other
Eligibility
55 Years to 90 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 5, 2021 · Synced Nov 15, 2026, 2:40 PM EST
Completed Not applicable Interventional Results available

Cognitive Behavioral Therapy to Treat Insomnia in Persons With HIV Infection

NCT03390114
View directory record Official record
Conditions
HIV/AIDS, Insomnia
Interventions
SHUTi
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 21, 2021 · Synced Nov 15, 2026, 2:40 PM EST
Completed Not applicable Interventional Accepts healthy volunteers Results available

Polysomnographic Study Comparing the Use of Dexmedetomidine and Zolpidem to Induce Natural Sleep

NCT01485393
View directory record Official record
Conditions
Insomnia
Interventions
Dexmedetomidine, Zolpidem
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 35 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 8, 2019 · Synced Nov 15, 2026, 2:40 PM EST
Recruiting Phase 2Phase 3 Interventional

A Study of TAK-360 in People With Narcolepsy or Idiopathic Hypersomnia

NCT07646678
View directory record Official record
Conditions
Idiopathic Hypersomnia, Narcolepsy Type 1, Narcolepsy Type 2
Interventions
TAK-360, Placebo
Drug
Lead sponsor
Takeda
Industry
Eligibility
18 Years to 71 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
22
States / cities
Chula Vista, California • Santa Ana, California • Colorado Springs, Colorado + 17 more
Source: ClinicalTrials.gov public record
Updated Nov 5, 2026 · Synced Nov 15, 2026, 2:40 PM EST
Not listed No phase listed Observational

In-Home Sleep Monitoring to Detect Suicide Risk in Veterans

NCT04744740
View directory record Official record
Conditions
Suicidal Ideation, Sleep Disturbance
Interventions
in-home sleep recording
Device
Lead sponsor
Palo Alto Veterans Institute for Research
Other
Eligibility
18 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Feb 9, 2021 · Synced Nov 15, 2026, 2:40 PM EST
Completed Phase 3 Interventional

Long-Term Efficacy and Safety of Ramelteon in Adults With Chronic Insomnia.

NCT00247390
View directory record Official record
Conditions
Chronic Insomnia
Interventions
Ramelteon, Placebo
Drug
Lead sponsor
Takeda
Industry
Eligibility
18 Years and older
Enrollment
451 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
19
States / cities
Birmingham, Alabama • Hot Springs, Arkansas • Los Angeles, California + 16 more
Source: ClinicalTrials.gov public record
Updated Jun 3, 2010 · Synced Nov 15, 2026, 2:40 PM EST
Not listed Not applicable Interventional Accepts healthy volunteers

Closed Loop TES for Enhancing Slow Wave Sleep

NCT03751982
View directory record Official record
Conditions
Sleep Disturbance, Insomnia
Interventions
Transcranial Electrical Neuromodulation (TES)
Device
Lead sponsor
Brain Electrophysiology Laboratory Company
Industry
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 23, 2018 · Synced Nov 15, 2026, 2:40 PM EST
Completed Not applicable Interventional

Optimizing an Integrated Mind and Body Treatment for Insomnia: The SLEEPS Study

NCT06626048
View directory record Official record
Conditions
Insomnia Disorder
Interventions
Cognitive Behavioral Therapy for Insomnia, Passive Body Heating (PBH)
Behavioral · Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Nov 15, 2026, 2:40 PM EST
Completed Phase 4 Interventional

Safety and Efficacy of Eszopiclone in Patients With Generalized Anxiety Disorder

NCT00235508
View directory record Official record
Conditions
Insomnia, Generalized Anxiety Disorder
Interventions
Eszopiclone (Lunesta)
Drug
Lead sponsor
Sumitomo Pharma America, Inc.
Industry
Eligibility
18 Years to 64 Years
Enrollment
420 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
64
States / cities
Birmingham, Alabama • Mesa, Arizona • Scottsdale, Arizona + 61 more
Source: ClinicalTrials.gov public record
Updated Feb 22, 2012 · Synced Nov 15, 2026, 2:40 PM EST
Recruiting Phase 2Phase 3 Interventional

A Study to Investigate the Effects of Cleminorexton Compared With Placebo in the Treatment of Participants With Central Disorders of Hypersomnolence

NCT07598708
View directory record Official record
Conditions
Narcolepsy Type 1, Narcolepsy Type 2
Interventions
cleminorexton, Placebo
Drug
Lead sponsor
Centessa Pharmaceuticals (UK) Limited
Industry
Eligibility
18 Years to 70 Years
Enrollment
222 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
26
States / cities
Birmingham, Alabama • Colorado Springs, Colorado • Brandon, Florida + 20 more
Source: ClinicalTrials.gov public record
Updated Nov 3, 2026 · Synced Nov 15, 2026, 2:40 PM EST
Completed No phase listed Observational

Observational Study of LUMRYZ in Narcolepsy

NCT06792708
View directory record Official record
Conditions
Narcolepsy
Interventions
LUMRYZ
Drug
Lead sponsor
Avadel
Industry
Eligibility
18 Years and older
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
12
States / cities
Bradenton, Florida • East Lansing, Michigan • Middletown, New Jersey + 9 more
Source: ClinicalTrials.gov public record
Updated Feb 13, 2026 · Synced Nov 15, 2026, 2:40 PM EST
Completed Not applicable Interventional

Behavioral Insomnia Therapy for Fibromyalgia

NCT00000397
View directory record Official record
Conditions
Fibromyalgia, Insomnia
Interventions
Behavioral insomnia therapy
Behavioral
Lead sponsor
Duke University
Other
Eligibility
21 Years to 65 Years
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2004
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 21, 2014 · Synced Nov 15, 2026, 2:40 PM EST
Recruiting Not applicable Interventional

Improving Sleep In Midlife Women

NCT07337915
View directory record Official record
Conditions
Poor Sleep Quality
Interventions
HealthyHabits1, HealthyHabits2, Snack 2, Snack 1
Behavioral · Other
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
45 Years to 65 Years · Female only
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Nov 15, 2026, 2:40 PM EST
Not yet recruiting Phase 2 Interventional

Supplemental Oxygen for Sleep-Disordered Breathing in Adults With Chronic Opioid Use.

NCT07923760
View directory record Official record
Conditions
Sleep-disordered Breathing, Chronic Opioid Use
Interventions
Sham Air, Supplemental Oxygen
Other · Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 75 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Nov 6, 2026 · Synced Nov 15, 2026, 2:40 PM EST
Completed Not applicable Interventional

The Effect of White Noise In High Noise Environment

NCT02647138
View directory record Official record
Conditions
Insomnia
Interventions
white noise
Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 100 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 17, 2019 · Synced Nov 15, 2026, 2:40 PM EST