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Showing 1–24 of 173 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Smoke Exposure Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Little Cigar and Cigarillo Warnings for Youth

NCT06413797
View directory record Official record
Conditions
Little Cigars and Cigarillos (LCC) Use
Interventions
FDA warnings + Image, FDA Warnings Text-Only, Surgeon General Text-Only Warnings
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
15 Years to 20 Years
Enrollment
928 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 23, 2025 · Synced Jun 7, 2026, 11:01 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Learning and Living With Wildfire Smoke

NCT06322966
View directory record Official record
Conditions
Behavior and Behavior Mechanisms, Health Knowledge, Attitudes, Practice
Interventions
Air Action Curriculum
Other
Lead sponsor
University of Washington
Other
Eligibility
14 Years and older
Enrollment
85 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 14, 2025 · Synced Jun 7, 2026, 11:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Circadian Rhythm Disruption Effects on Smoke Inhalation

NCT04955431
View directory record Official record
Conditions
Inflammation, Sleep Deprivation, Circadian Rhythm Sleep Disorder, Shift Work Type, Smoke Inhalation
Interventions
Sleep Restriction, Normal Sleep
Behavioral
Lead sponsor
University of Montana
Other
Eligibility
18 Years to 44 Years · Male only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Missoula, Montana
Source: ClinicalTrials.gov public record
Updated May 29, 2025 · Synced Jun 7, 2026, 11:01 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Effects of Wood Smoke Particles on Influenza-induced Nasal Inflammation in Normal Volunteers

NCT02183753
View directory record Official record
Conditions
Response of Viral Infection to Woodsmoke
Interventions
wood smoke, clean air
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 40 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 10, 2015 · Synced Jun 7, 2026, 11:01 AM EDT
Completed Not applicable Interventional

Clinical Effort Against Smoke Exposure in Cystic Fibrosis

NCT04777344
View directory record Official record
Conditions
Cystic Fibrosis
Interventions
Tobacco Treatment Specialist (TTS) intervention
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 5, 2022 · Synced Jun 7, 2026, 11:01 AM EDT
Completed Not applicable Interventional

A Trial of Positively Smoke Free Group Therapy for HIV-infected Smokers

NCT02072772
View directory record Official record
Conditions
Tobacco Use in Persons Living With HIV
Interventions
Positively Smoke Free group treatment, Standard Care
Behavioral
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years to 99 Years
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
2
States / cities
Washington D.C., District of Columbia • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Oct 5, 2025 · Synced Jun 7, 2026, 11:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Switching Individuals in Treatment for Opioid Use Disorder Who Smoke Cigarettes to the SREC

NCT05881304
View directory record Official record
Conditions
Electronic Cigarette Use
Interventions
Standardized research e-cigarette (SREC)
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Jun 7, 2026, 11:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Environmental Emissions From Electronic Cigarettes and Tobacco-Burning Cigarettes

NCT02185898
View directory record Official record
Conditions
Smoking
Interventions
Leading U.S. non-menthol cigarette, Leading U.S. menthol cigarette, Electronic cigarette #1, Electronic cigarette #2, Electronic cigarette #3, U.S. Market-sample electronic cigarettes
Other
Lead sponsor
R.J. Reynolds Vapor Company
Industry
Eligibility
21 Years to 99 Years
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Stockbridge, Georgia
Source: ClinicalTrials.gov public record
Updated May 31, 2018 · Synced Jun 7, 2026, 11:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Financial Incentives to Reduce Pediatric Tobacco Smoke Exposures

NCT03099811
View directory record Official record
Conditions
Asthma, Incentives, Tobacco Smoking
Interventions
Incentive plan, Smoking cessation
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
2 Years to 12 Years
Enrollment
147 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 19, 2018 · Synced Jun 7, 2026, 11:01 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Motivational Incentives to Reduce Secondhand Smoke in NICU Infants' Homes

NCT01726062
View directory record Official record
Conditions
Exposure to Secondhand Smoke in Neonatal Infants
Interventions
Motivational Interviewing plus Incentives, Conventional Care (CC)
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
Not listed
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2018
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 13, 2018 · Synced Jun 7, 2026, 11:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effective Ads for Quitting Smoking

NCT06485479
View directory record Official record
Conditions
Smoking Behaviors
Interventions
Intervention ads, Control ads
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
21 Years and older
Enrollment
1,236 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 2, 2025 · Synced Jun 7, 2026, 11:01 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Combination SBIRT for Emergency Department Patients Who Drink and Smoke

NCT01595178
View directory record Official record
Conditions
Smoking, Drinking
Interventions
Combined BNI
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 25, 2020 · Synced Jun 7, 2026, 11:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Brief Interventions to Create Smoke-Free Home Policies in Low-Income Households

NCT01625468
View directory record Official record
Conditions
Chronic Diseases
Interventions
Educational print materials and a coaching call
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 9, 2015 · Synced Jun 7, 2026, 11:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Biomarkers of Exposure and Biomarkers of Potential Harm in Adult Smokers Who Completely Switch to E-vapor Products

NCT04800211
View directory record Official record
Conditions
Tobacco Use
Interventions
Experimental: Test Product 1, Experimental: Test Product 2
Other
Lead sponsor
Altria Client Services LLC
Industry
Eligibility
30 Years to 65 Years
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
10
States / cities
Burbank, California • Wichita, Kansas • Lexington, Kentucky + 7 more
Source: ClinicalTrials.gov public record
Updated Mar 11, 2025 · Synced Jun 7, 2026, 11:01 AM EDT
Completed No phase listed Observational

Environmental Exposures, Genetics, and Exhaled Nitric Oxide in Pediatric Asthma

NCT00395096
View directory record Official record
Conditions
Asthma
Interventions
Not listed
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
6 Years to 12 Years
Enrollment
225 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 8, 2021 · Synced Jun 7, 2026, 11:01 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Measuring Environmental Tobacco and Cannabis: Pollutants and Exposures

NCT06030674
View directory record Official record
Conditions
Healthy
Interventions
Secondhand cannabis emissions/smoke exposure
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years to 50 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 10, 2023 · Synced Jun 7, 2026, 11:01 AM EDT
Withdrawn Phase 2 Interventional

Cotinine Feedback as an Intervention to Change Parental/Caregiver Smoking Behavior Around Children With Cancer

NCT01828502
View directory record Official record
Conditions
Pediatric Cancer
Interventions
Education, Cotinine Education
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
2 Years to 12 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
10
States / cities
Wilmington, Delaware • Fort Myers, Florida • Jacksonville, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Oct 28, 2014 · Synced Jun 7, 2026, 11:01 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

E-Cigarette Aerosol, Conventional Cigarette Smoke, and Myocardial Perfusion

NCT02612701
View directory record Official record
Conditions
Coronary Artery Disease, Myocardial Perfusion
Interventions
Cigarettes, E-cigarettes (nicotine free e-liquid), E-cigarettes (low nicotine e-liquid), E-cigarettes (high nicotine e-liquid)
Other
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years to 49 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 3, 2021 · Synced Jun 7, 2026, 11:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Developing and Pilot Testing an Intervention to Reduce Household Shisha Smoke Exposure Within Somali Homes

NCT06316947
View directory record Official record
Conditions
Shisha
Interventions
CHW-delivered intervention
Radiation
Lead sponsor
University of Minnesota
Other
Eligibility
6 Months and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Jun 7, 2026, 11:01 AM EDT
Completed Phase 2 Interventional

Prevention of Environmental Tobacco Smoke Exposure in Children 0-12 Months Old

NCT00340106
View directory record Official record
Conditions
Environmental Tobacco Smoke (ETS)
Interventions
Counseling
Behavioral
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
18 Years and older · Female only
Enrollment
375 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
2
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Jun 7, 2026, 11:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Smoke-free Home Intervention in Permanent Supportive Housing

NCT04855357
View directory record Official record
Conditions
Smoking Cessation, Second Hand Tobacco Smoke
Interventions
Resident counselling, Staff Training
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
452 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Jun 7, 2026, 11:01 AM EDT
Completed No phase listed Observational

Lupus Nephritis: Role of Environmental and Occupational Exposures

NCT00342329
View directory record Official record
Conditions
Lupus Nephritis
Interventions
Not listed
Lead sponsor
National Institute of Environmental Health Sciences (NIEHS)
NIH
Eligibility
Not listed
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2007
U.S. locations
2
States / cities
Chapel Hill, North Carolina • Research Triangle Park, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Jun 7, 2026, 11:01 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Tobacco Cessation Texting Intervention for People Living With HIV Who Smoke in Vietnam

NCT05863923
View directory record Official record
Conditions
Tobacco Cessation
Interventions
mHealth Messaging to Motivate Quitline use and Quitting among Persons Living With HIV (PLWH) in Vietnam (M2Q2-HIV), M2Q2-HIV Comparison
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 21, 2025 · Synced Jun 7, 2026, 11:01 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

A Study of Gamma Tocopherol-enriched Supplement on Lower Airway Responses to Inhaled Wood Smoke in Healthy Adults

NCT03444298
View directory record Official record
Conditions
Airway Inflammation, Asthma
Interventions
Gamma Tocopherol, Placebo
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 45 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 4, 2024 · Synced Jun 7, 2026, 11:01 AM EDT