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ClinicalTrials.gov public records Last synced Oct 20, 2026, 8:20 AM EDT

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Showing 49–72 of 181 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Smoke Exposure Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Examining Brain Responses Linked to Emotion in Individuals Who Smoke Cigarettes

NCT04310735
View directory record Official record
Conditions
Smoking, Tobacco
Interventions
Verbal smoking expectancy manipulation
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
21 Years to 55 Years
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 7, 2025 · Synced Oct 20, 2026, 8:20 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Tobacco Cessation Texting Intervention for People Living With HIV Who Smoke in Vietnam

NCT05863923
View directory record Official record
Conditions
Tobacco Cessation
Interventions
mHealth Messaging to Motivate Quitline use and Quitting among Persons Living With HIV (PLWH) in Vietnam (M2Q2-HIV), M2Q2-HIV Comparison
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Oct 20, 2026, 8:20 AM EDT
Completed Not applicable Interventional

A Study of Tobacco Smoke and Children With Respiratory Illnesses

NCT03062709
View directory record Official record
Conditions
Bronchiolitis, Pneumonia, Reactive Airway Disease, Asthma, Tobacco Smoking, Tobacco Cessation, Bronchopulmonary Dysplasia
Interventions
Breathe Easy Coalition written materials, Maine Tobacco Helpline, Urine cotinine testing
Behavioral · Diagnostic Test
Lead sponsor
MaineHealth
Other
Eligibility
Up to 10 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Portland, Maine
Source: ClinicalTrials.gov public record
Updated May 16, 2017 · Synced Oct 20, 2026, 8:20 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

ASPIRE Health Tulare County

NCT05944770
View directory record Official record
Conditions
Respiratory Tract Diseases, Cardiovascular Diseases
Interventions
DIY portable air cleaner with a highly effective filter, DIY portable air cleaner with sham filtration
Other
Lead sponsor
Environmental Protection Agency (EPA)
Federal
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Fresno, California
Source: ClinicalTrials.gov public record
Updated Oct 27, 2023 · Synced Oct 20, 2026, 8:20 AM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

Cardiovascular Effects of Exposure to Wood Smoke in Healthy Human Adults

NCT04297761
View directory record Official record
Conditions
Healthy
Interventions
Filtered Air, Wood Smoke
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 35 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 12, 2025 · Synced Oct 20, 2026, 8:20 AM EDT
Completed No phase listed Observational

Room Air Levels of Harmful and Potentially Harmful Constituents After Heated Tobacco Product Use and Cigarettes

NCT06476405
View directory record Official record
Conditions
Tobacco Smoking, Tobacco Use
Interventions
Not listed
Lead sponsor
Altria Client Services LLC
Industry
Eligibility
22 Years to 65 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Stockbridge, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Oct 20, 2026, 8:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reducing Tobacco Exposures Among African American Women and Children

NCT03476837
View directory record Official record
Conditions
Tobacco Use, Second Hand Tobacco Smoke
Interventions
Treatment, Control
Behavioral
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years to 50 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Oct 20, 2026, 8:20 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Implementing a Scalable Smoke-free Home Intervention in Armenia and Georgia

NCT06166433
View directory record Official record
Conditions
Second Hand Tobacco Smoke
Interventions
Smoke-free homes intervention
Behavioral
Lead sponsor
George Washington University
Other
Eligibility
18 Years and older
Enrollment
550 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Mar 23, 2026 · Synced Oct 20, 2026, 8:20 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Clinical Response to Biomarker Documentation of Child Secondhand Smoke Exposure

NCT01145729
View directory record Official record
Conditions
Biomarker Feedback, Smoking Cessation, Secondhand Smoke Exposure, Provider Behavior
Interventions
Biomarker Feedback
Behavioral
Lead sponsor
National Institutes of Health (NIH)
NIH
Eligibility
12 Months to 36 Months
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 17, 2010 · Synced Oct 20, 2026, 8:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A 26-week Extension of the ZRHR-ERS-09-US Study Evaluating Biological and Functional Changes in Healthy Smokers After Switching to THS 2.2

NCT02649556
View directory record Official record
Conditions
Smoking
Interventions
THS 2.2, CC
Other
Lead sponsor
Philip Morris Products S.A.
Industry
Eligibility
30 Years and older
Enrollment
672 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
19
States / cities
Tempe, Arizona • Clearwater, Florida • Daytona Beach, Florida + 16 more
Source: ClinicalTrials.gov public record
Updated Dec 4, 2020 · Synced Oct 20, 2026, 8:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Project CASA in Promoting Smoke-Free Indoor Air Policy in Mexican American Households

NCT00850954
View directory record Official record
Conditions
Cigarette Smoker, Current Smoker, Currently Living With Smoker
Interventions
Informational Intervention, Smoking Cessation Intervention, Survey Administration
Other · Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
168 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2018
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 28, 2023 · Synced Oct 20, 2026, 8:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Supporting Smoke-Free Policy Compliance in Public Housing

NCT05016505
View directory record Official record
Conditions
Smoking, Smoking Cessation, Smoking Reduction, Smoking Behaviors
Interventions
Reduction (relocation and reduction of personal smoking) and cessation, Resident Endorsement
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
405 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Oct 20, 2026, 8:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Reduced Exposure Study Using THS 2.2 Menthol With 5 Days in a Confinement Setting Followed by 86 Days in an Ambulatory Setting

NCT01989156
View directory record Official record
Conditions
Smoking
Interventions
THS 2.2 Menthol (mTHS 2.2), Menthol Conventional Cigarette (mCC), Smoking Abstinence (SA)
Other
Lead sponsor
Philip Morris Products S.A.
Industry
Eligibility
22 Years and older
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
2
States / cities
Daytona Beach, Florida • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 24, 2020 · Synced Oct 20, 2026, 8:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dose-dependent Effects of Second-hand Smoke on Vascular Function

NCT01007760
View directory record Official record
Conditions
Cardiovascular Disease
Interventions
Respirable suspended particles (RSP) PM 2.5 dose of second-hand smoke
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 40 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 19, 2011 · Synced Oct 20, 2026, 8:20 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

WebQuit Online Smoking Cessation Study

NCT01166334
View directory record Official record
Conditions
Smoking
Interventions
WebQuit study group, WebQuit control group
Behavioral
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
721 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 11, 2013 · Synced Oct 20, 2026, 8:20 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

GABA (Gamma Amino Butyric Acid) Medication for Tobacco

NCT00644137
View directory record Official record
Conditions
Nicotine Dependence
Interventions
pregabalin, cigarettes
Drug · Other
Lead sponsor
Yale University
Other
Eligibility
18 Years to 55 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 2, 2020 · Synced Oct 20, 2026, 8:20 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Motivational Incentives to Reduce Secondhand Smoke in NICU Infants' Homes

NCT01726062
View directory record Official record
Conditions
Exposure to Secondhand Smoke in Neonatal Infants
Interventions
Motivational Interviewing plus Incentives, Conventional Care (CC)
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
Not listed
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2018
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 14, 2018 · Synced Oct 20, 2026, 8:20 AM EDT
Completed No phase listed Observational

Environmental Exposures, Genetics, and Exhaled Nitric Oxide in Pediatric Asthma

NCT00395096
View directory record Official record
Conditions
Asthma
Interventions
Not listed
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
6 Years to 12 Years
Enrollment
225 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 9, 2021 · Synced Oct 20, 2026, 8:20 AM EDT
Active, not recruiting Not applicable Interventional

Laying the Foundation for Building a Resilient KPNC Community in the Face of Worsening Air Quality Due to Wildfire Smoke

NCT07118189
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease (COPD), Exacerbation of COPD, Exacerbation of Chronic Obstructive Pulmonary Disease
Interventions
N95 masks and indoor air cleaner
Device
Lead sponsor
Kaiser Permanente
Other
Eligibility
65 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Pleasanton, California
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Oct 20, 2026, 8:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Meditative Movement for COPD Symptoms in Non-Smoking Flight Attendants

NCT02612389
View directory record Official record
Conditions
Pulmonary Disease, Autonomic Dysfunction, COPD
Interventions
Meditative Movement taught via DVD
Other
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
Not listed
Enrollment
220 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2020
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Aug 18, 2020 · Synced Oct 20, 2026, 8:20 AM EDT
Enrolling by invitation Not applicable Interventional

A Patient-Oriented Research Mentoring Program in Tobacco Dependence and Implementation Science Research

NCT05852860
View directory record Official record
Conditions
HIV, Smoking, Tobacco Use, Nicotine Dependence
Interventions
Clinician Nudge, Patient Nudge
Other
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
Not listed
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 14, 2026 · Synced Oct 20, 2026, 8:20 AM EDT
Completed No phase listed Observational

Lupus Nephritis: Role of Environmental and Occupational Exposures

NCT00342329
View directory record Official record
Conditions
Lupus Nephritis
Interventions
Not listed
Lead sponsor
National Institute of Environmental Health Sciences (NIEHS)
NIH
Eligibility
Not listed
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2007
U.S. locations
2
States / cities
Chapel Hill, North Carolina • Research Triangle Park, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 20, 2026, 8:20 AM EDT
Recruiting Phase 4 Interventional

Modifying Progesterone and Estradiol Levels to Prevent Postpartum Cigarette Smoking Relapse and Reduce Secondhand Smoke Exposure in Infants and Children

NCT04783857
View directory record Official record
Conditions
Smoking, Smoking Cessation, Smoking Reduction
Interventions
Progesterone 200 MG Oral Capsule
Drug
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
171 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Oct 20, 2026, 8:20 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Increasing Access to Smoking Cessation and Smoke Free Home Services for Low-Income Pregnant Women in Northeast Texas

NCT05051345
View directory record Official record
Conditions
Cigarette Smoking-Related Carcinoma
Interventions
Informational Intervention, Media Intervention, Questionnaire Administration, Smoking Cessation Intervention, Survey Administration, Telephone-Based Intervention, Tobacco Cessation Counseling
Other · Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
191 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 15, 2026 · Synced Oct 20, 2026, 8:20 AM EDT