Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 4, 2026, 10:17 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 241–264 of 797 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Smoker Clear all

Conditions: Smokers With Chronic Pain
Interventions: Psilocybin (drug); Drug
Lead sponsor: Yale University; Other
Eligibility: 21 Years to 65 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: West Haven, Connecticut

Conditions: Minority Smokers
Interventions: Patient Navigator; Behavioral
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2021
U.S. locations: 2
States / cities: New York, New York

Conditions: Smoking Cessation
Interventions: Nicotine Replacement Therapy, Smoking Cessation Counseling; Drug · Behavioral
Lead sponsor: University of Kansas Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 278 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2018
U.S. locations: 2
States / cities: Kansas City, Kansas • Kansas City, Missouri

Conditions: Smoking Cessation
Interventions: Varenicline 1mg BID, Varenicline 0.5mg BID, Placebo; Drug
Lead sponsor: Pfizer; Industry
Eligibility: 12 Years to 19 Years
Enrollment: 312 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2018
U.S. locations: 56
States / cities: Ozark, Alabama • Goodyear, Arizona • Little Rock, Arkansas + 46 more

Conditions: Nicotine Dependence, Cigarette Smoking, Insomnia
Interventions: Cognitive-Behavioral Counseling, Smoking Cessation Counseling; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 75 Years
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Lung Cancer
Interventions: Not listed
Lead sponsor: National Human Genome Research Institute (NHGRI); NIH
Eligibility: 18 Years to 55 Years
Enrollment: 757 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2010
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Substance Related Disorder, Nicotine Dependence
Interventions: Nicotine; Drug
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years to 50 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Tobacco Use, Smoking, Tobacco Dependence, Tobacco Use Disorder, Tobacco Use Cessation, Tobacco Smoking, Smoking Cessation, Smoking, Cigarette, Smoking, Tobacco
Interventions: POP:, TSP:; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years to 25 Years
Enrollment: 165 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Healthy Volunteers
Interventions: Pomalidomide, Caffeine, Tobacco; Drug · Other
Lead sponsor: Celgene; Industry
Eligibility: 40 Years to 80 Years
Enrollment: 55 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014
U.S. locations: 1
States / cities: Daytona Beach, Florida

Conditions: Smoking
Interventions: Broccoli sprout homogenate, Alfalfa sprout homogenate; Dietary Supplement
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 40 Years
Enrollment: 51 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: COPD
Interventions: Not listed
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older
Enrollment: 72 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2008
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Tobacco Use
Interventions: VLN menthol cigarettes (A), Usual Brand Menthol Cigarettes (B), Nicotine gum (C); Other · Drug
Lead sponsor: 22nd Century Group, Inc.; Industry
Eligibility: 22 Years to 65 Years
Enrollment: 55 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018
U.S. locations: 1
States / cities: Overland Park, Kansas

Conditions: Lung Cancer
Interventions: Biomarker (not used as an intervention); Device
Lead sponsor: Allegro Diagnostics, Corp.; Industry
Eligibility: 21 Years and older
Enrollment: 1,331 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2015
U.S. locations: 21
States / cities: Birmingham, Alabama • Phoenix, Arizona • Sacramento, California + 17 more

Conditions: Electronic Nicotine Delivery System Flavors
Interventions: Tobacco product administration and assessment; Other
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 21 Years and older
Enrollment: 71 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: HIV/AIDS, Vitamin D Deficiency, Smoker Lung
Interventions: Vitamin D3 450,000 IU orally; Drug
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018
U.S. locations: 2
States / cities: Atlanta, Georgia

Conditions: Smoking, Tobacco
Interventions: Internal Care Coordination, External Community Referral, Usual Care; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 234 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Nicotine Addiction
Interventions: Saline, Nicotine; Drug
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 30 Years
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: West Haven, Connecticut

Conditions: Substance Withdrawal Syndrome
Interventions: dehydroepiandrosterone (DHEA), pregnenolone, Placebo; Dietary Supplement · Drug
Lead sponsor: Jed E. Rose; Other
Eligibility: 18 Years to 65 Years · Male only
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 2
States / cities: Durham, North Carolina • Raleigh, North Carolina

Conditions: Nicotine Use Disorder
Interventions: Practice Quit Attempt; Other
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years to 45 Years
Enrollment: 82 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2023
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Tobacco Use Cessation, Smoking Cessation, Smoking, Tobacco Use Disorder
Interventions: Brief Intervention with NRT Initiation; Other
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 780 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Nicotine Dependence, Other Tobacco Product, Tobacco Use, Smoking, Tobacco
Interventions: Treatment with JUUL 5%, Virginia Tobacco, Treatment with JUUL 5%, Cool Mint, ENDS, Treatment with JUUL 5%, Mango, ENDS, JUUL 5%, Creme Bruele, ENDS, Combustible cigarette, Smoking Cessation; Other
Lead sponsor: Juul Labs, Inc.; Industry
Eligibility: 21 Years to 65 Years
Enrollment: 90 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018
U.S. locations: 1
States / cities: Lincoln, Nebraska

Conditions: Healthy Subjects
Interventions: GW876008; Drug
Lead sponsor: GlaxoSmithKline; Industry
Eligibility: 18 Years to 45 Years
Enrollment: 26 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: Started 2006
U.S. locations: 1
States / cities: Willingboro, New Jersey

Conditions: Cigarette Smoking, Alcohol Use Disorders
Interventions: Varenicline, Prazosin, Placebo; Drug
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Cigarette Smoking-Related Carcinoma, Tobacco-Related Carcinoma
Interventions: Broccoli Sprout/Broccoli Seed Extract Supplement, Laboratory Biomarker Analysis, Questionnaire Administration; Drug · Other
Lead sponsor: National Cancer Institute (NCI); NIH
Eligibility: 18 Years and older
Enrollment: 49 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2022
U.S. locations: 2
States / cities: Tucson, Arizona

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Psilocybin as a Treatment for Chronic Pain in Smokers

Tobacco-Focused Patient Navigation to Address Barriers to Utilization of Community-Based Smoking Cessation Services in Primary Care

Informing Tobacco Treatment Guidelines for African American Non-Daily Smokers

Smoking Cessation Study In Healthy Adolescent Smokers

Smoking Cessation for Smokers With Sleep Problems

Impact of Lung Cancer Diagnosis on Relatives' Understanding of Genetic Risk and Receptivity to Quit Smoking

Effects of Nicotine on Elements of Attentions in Smokers and Nonsmokers

A Facebook Intervention for Young Sexual and Gender Minority Smokers

Food Effect and CYP1A2 Induction Study in Healthy Subjects

Effects of Sulforaphane (SFN) on Immune Response to Live Attenuated Influenza Virus in Smokers and Nonsmokers

Functional Proteomics of Alveolar Macrophages

Evaluation of Abuse Liability of Very Low Nicotine (VLN) Mentholated Cigarettes

Airway Epithelium Gene Expression: AEGIS IDE

Potential Effects of Electronic Nicotine Delivery System Flavor Regulations on African American Menthol Smokers

Effect of High-Dose Vitamin D3 in Smokers and Non-Smokers With and Without HIV

Proactive Population Health Strategy to Offer Tobacco Dependence Treatment to Smokers

Nicotine Reinforcement and Aversion in Young Adult Light Smokers

The Effects of One-Time Pregnenolone, Dehydroepiandrosterone (DHEA), or Placebo Administration On Withdrawal Symptoms, Mood, Craving And Cigarette Evaluation Ratings In Male Smokers

Neural Basis of Eating Behavior in Abstinent Smokers

Treating Low-Income Smokers in the Hospital Emergency Department

Identify Biomarkers of Tobacco Exposure and Nicotine Uptake From JUUL 5% in Adult Smokers

A Study To Investigate The Metabolism Of GW876008 In Smokers Compared To Non-Smokers.

Varenicline + Prazosin for Heavy Drinking Smokers

Broccoli Sprout/Broccoli Seed Extract Supplement in Decreasing Toxicity in Heavy Smokers