Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 6, 2026, 6:52 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 289–312 of 797 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Smoker Clear all

Conditions: Cigarette Smoking
Interventions: Low-nitrosamine smokefree tobacco product for oral use, Non-tobacco, non-nicotine placebo product; Drug · Other
Lead sponsor: Swedish Match AB; Industry
Eligibility: 25 Years to 65 Years
Enrollment: 250 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2010
U.S. locations: 4
States / cities: Daytona Beach, Florida • Evansville, Indiana • Portland, Oregon + 1 more

Conditions: Chronic Pain, Smoking, Smoking Cessation
Interventions: Tailored intervention, Ask-Advise-Refer; Behavioral
Lead sponsor: Syracuse University; Other
Eligibility: 18 Years and older
Enrollment: 76 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016
U.S. locations: 1
States / cities: Syracuse, New York

Conditions: Nicotine Use Disorder
Interventions: Active 10-Hz TMS to the DLPFC, Sham TMS-DLPFC; Device
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 18 Years to 55 Years
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Newark, New Jersey

Conditions: Smoking, Tobacco Use, Tobacco Smoking
Interventions: 40007388, 40007385, 40007387, 40007386; Other
Lead sponsor: RAI Services Company; Industry
Eligibility: 21 Years to 60 Years
Enrollment: 1,180 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 10
States / cities: Atlanta, Georgia • Chicago, Illinois • Baltimore, Maryland + 7 more

Conditions: Lung Cancer
Interventions: Not listed
Lead sponsor: National Human Genome Research Institute (NHGRI); NIH
Eligibility: 18 Years to 55 Years
Enrollment: 757 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2010
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Substance Related Disorder, Nicotine Dependence
Interventions: Nicotine; Drug
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years to 50 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Smoking
Interventions: Brief computerized feedback, Resources only (control); Other
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years and older
Enrollment: 151 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Midlothian, Virginia

Conditions: Tobacco Use
Interventions: Graphic cigarette warning labels, plain packaging; Behavioral
Lead sponsor: Georgetown University; Other
Eligibility: 18 Years to 30 Years
Enrollment: 400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2020
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Smoking Reduction
Interventions: Varenicline Tartrate, Placebo, Electronic cigarette; Drug · Other
Lead sponsor: University of Kansas Medical Center; Other
Eligibility: 21 Years and older
Enrollment: 500 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 2
States / cities: Kansas City, Missouri

Conditions: Lung Carcinoma
Interventions: Liquid Biopsy, Low Dose Computed Tomography of the Chest, Survey Administration; Procedure · Other
Lead sponsor: City of Hope Medical Center; Other
Eligibility: 50 Years to 80 Years
Enrollment: 108 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Duarte, California

Conditions: Smoking Cessation, Overweight, Obesity
Interventions: Nicotine patch; Drug
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 54 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Smoking
Interventions: Telephone counseling, Self-help materials; Behavioral
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 1,173 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2000 – 2004
U.S. locations: 1
States / cities: San Diego, California

Conditions: Pelvic Organ Prolapse
Interventions: Blood draw for the study participants; Other
Lead sponsor: TriHealth Inc.; Other
Eligibility: 18 Years and older · Female only
Enrollment: 96 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Smoking, Motivation, Smoking Cessation
Interventions: Nicotine Mini-Lozenge, Behavioral Reduction Counseling, 5Rs Motivation Counseling, Behavioral Activation Counseling, No Treatment; Drug · Behavioral · Other
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years and older
Enrollment: 577 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Nicotine Dependence
Interventions: Financial Incentives; Behavioral
Lead sponsor: University of Georgia; Other
Eligibility: 18 Years and older
Enrollment: 190 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Athens, Georgia

Conditions: Oral Disease, Smoking
Interventions: Usual Care Control, Enhanced Intervention; Behavioral
Lead sponsor: Kaiser Permanente; Other
Eligibility: 18 Years and older
Enrollment: 718 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Tobacco Use Disorder
Interventions: Behavior Therapy; Behavioral
Lead sponsor: University of Minnesota; Other
Eligibility: 40 Years to 79 Years · Female only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1997 – 2003
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Healthy, Brain Reactivity of Non-smokers Undergoing fMRI Scanning
Interventions: Not listed
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 55 Years
Enrollment: 116 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: COPD
Interventions: Perfluorinated Gas/Oxygen Mixture, High Resolution CT of the Chest; Drug · Other
Lead sponsor: Hal C Charles; Other
Eligibility: 18 Years and older
Enrollment: 171 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2018
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Nicotine Dependence
Interventions: Preparation Varenicline and Standard Duration Varenicline, Preparation Varenicline and Extended Duration Varenicline, Standard Duration Varenicline, Extended Duration Varenicline, Preparation Combination NRT and Standard Duration Combination NRT, Preparation Combination NRT and Extended Duration Combination NRT, Standard Duration Combination NRT, Extended Duration Combination NRT, Intensive Counseling, Minimal Counseling; Drug · Behavioral
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years and older
Enrollment: 538 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2025
U.S. locations: 2
States / cities: Madison, Wisconsin • Milwaukee, Wisconsin

Conditions: Smoking, Tobacco Use, Cigarette Smoking, E-Cig Use
Interventions: E-cigarettes; Other
Lead sponsor: Abramson Cancer Center at Penn Medicine; Other
Eligibility: 21 Years and older
Enrollment: 210 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Asthma
Interventions: fluticasone/salmeterol in all asthmatics, budesonide/formoterol or fluticasone/salmeterol in all asthmatics; Drug
Lead sponsor: Gelb, Arthur F., M.D.; Individual
Eligibility: 10 Years to 80 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2027
U.S. locations: 1
States / cities: Lakewood, California

Conditions: Tobacco Use
Interventions: Ploom HTP Menthol HTS; MX3 (681), Ploom HTP Tobacco HTS; R8 (120), Smoking Abstinence (menthol), Smoking Abstinence (non-menthol); Other
Lead sponsor: Altria Client Services LLC; Industry
Eligibility: 22 Years to 65 Years
Enrollment: 921 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 8
States / cities: Bentonville, Arkansas • Rogers, Arkansas • Overland Park, Kansas + 5 more

Conditions: Alcoholism, Nicotine Dependence
Interventions: Varenicline; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 70 Years
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Rochester, Minnesota

Search by objective public record fields.

Controlled Study of the Ability of a Smokefree Tobacco Product to Increase the Quit Rate Among Cigarette Smokers

Increasing Cessation Motivation and Treatment Engagement Among Smokers in Pain

Identify the Optimal TMS Target to Modulate Reward Activity

CSD210904: Study to Assess Actual Use of a Heated Tobacco Product With Four Non-Combusted Cigarette Variants in Current Adult Smokers

Impact of Lung Cancer Diagnosis on Relatives' Understanding of Genetic Risk and Receptivity to Quit Smoking

Effects of Nicotine on Elements of Attentions in Smokers and Nonsmokers

Brief Computerized Feedback for Smokers in Recovery

Effect of Cigarette Pack Warnings and Packaging Among Young Adult Smokers

Switching to E-cigarettes in Smokers Not Interested in Quitting

Feasibility of Cell-Free DNA Liquid Biopsy in Screening High-Risk Patients for Lung Cancer

Internet-Administered Smoking Cessation Treatment for Overweight and Obese Smokers

Telephone Counseling for Pregnant Smokers

Systemic Markers of Collagen Metabolism and Vitamin C in Smokers and Non-Smokers With Pelvic Organ Prolapse

Motivation Project: Testing Intervention Components for the Smoker Who is Unwilling to Quit

Testing Financial Incentive Interventions in Dyadic-Smoker Couples

Promoting Oral Health Among Smokers Randomized Trial

Tobacco Cessation in Postmenopausal Women (Part I) - 1

Memory and Picture Viewing Study

Imaging Regional Lung Defect Severity

Cessation Screening Project

The Role of Flavor in the Substitutability of E-cigarettes for Combustible Cigarettes Among Persistent Smokers

Mechanism(s) of Airflow Limitation During Exacerbation of Asthma

Changes in Biomarker of Exposure in Adults Who Smoke Cigarettes Switching From Cigarettes to Heated Tobacco Products

Varenicline and Alcohol in Inpatient Addictions Program (IAP)