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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Smoking, Cessation Clear all
Completed Phase 3 Interventional Results available

Smoking Cessation With the Nicotine Patch: A Pilot Study of Patch Messaging

NCT01287377
View directory record Official record
Conditions
Smoking Cessation
Interventions
Telephone Counseling, Nicotine Patches
Behavioral · Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
243 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Feb 12, 2020 · Synced Jul 23, 2026, 6:27 PM EDT
Completed Not applicable Interventional Results available

Phone-Based Postpartum Continuing Care for Smoking Cessation

NCT01684592
View directory record Official record
Conditions
Smoking Cessation, Pregnancy
Interventions
Phone-based postpartum continuing care, Standard care
Behavioral
Lead sponsor
Battelle Memorial Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
2
States / cities
Bloomington, Illinois • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 12, 2018 · Synced Jul 23, 2026, 6:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pivot Breath Sensor Performance Study

NCT03870022
View directory record Official record
Conditions
Smoking Cessation, Smoking, Tobacco
Interventions
Pivot Breath Sensor System, Similar Carbon Monoxide breath sensor system
Device
Lead sponsor
Jennifer Marler, MD
Industry
Eligibility
18 Years to 80 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated Jun 30, 2024 · Synced Jul 23, 2026, 6:27 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Adverse Airway Effects From Tobacco and E-Cigarettes

NCT03251053
View directory record Official record
Conditions
Airway Morbidity, Smoking Cessation, Nicotine Adverse Reaction, Smoking, Tobacco, Smoking, Cigarette
Interventions
Electronic cigarette use, Control regular cigarette smokers
Device · Other
Lead sponsor
Miami VA Healthcare System
Federal
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 15, 2017 · Synced Jul 23, 2026, 6:27 PM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Semaglutide for Post-Smoking Cessation Weight Management

NCT06173778
View directory record Official record
Conditions
Obesity, Overweight, Cigarette Smoking
Interventions
semaglutide 2.4mg, Placebo, Nicotine Replacement Therapy (NRT, nicotine patch), Brief Smoking Cessation Counseling
Drug · Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 75 Years
Enrollment
197 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
2
States / cities
Austin, Texas • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 10, 2026 · Synced Jul 23, 2026, 6:27 PM EDT
Completed Not applicable Interventional

Smoking Cessation Intervention for Smokers With Depression Receiving Outpatient Psychiatric Treatment

NCT02742610
View directory record Official record
Conditions
Smoking Cessation
Interventions
Mindfulness with Contingency Management, Active Control
Behavioral
Lead sponsor
Fordham University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jan 14, 2019 · Synced Jul 23, 2026, 6:27 PM EDT
Completed Phase 4 Interventional Results available

Randomized Study Comparing the Efficacy and Safety of Varenicline Tartrate to Placebo in Smoking Cessation When Subjects Are Allowed to Set Their Own Quit Date

NCT00691483
View directory record Official record
Conditions
Smoking Cessation
Interventions
placebo, varenicline
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 75 Years
Enrollment
659 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
12
States / cities
Litchfield Park, Arizona • Los Angeles, California • Santa Ana, California + 9 more
Source: ClinicalTrials.gov public record
Updated Nov 19, 2015 · Synced Jul 23, 2026, 6:27 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Varenicline Augmentation of Patch Outcomes in Heavy Drinkers' Smoking Cessation

NCT02859142
View directory record Official record
Conditions
Smoking Cessation, Alcohol Drinking
Interventions
Chantix, Behavioral Counseling Sessions, NicodermCQ, Placebo
Drug · Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 85 Years
Enrollment
122 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 26, 2021 · Synced Jul 23, 2026, 6:27 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Digitally Enhanced Smoking Cessation for High Risk Smokers

NCT04691297
View directory record Official record
Conditions
Smoking, Smoking Cessation, Lung Cancer Screening, Smoking, Tobacco, Smoking Behaviors
Interventions
Escape, Standard Care
Other
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
55 Years to 77 Years
Enrollment
153 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 18, 2025 · Synced Jul 23, 2026, 6:27 PM EDT
Recruiting Not applicable Interventional

Precision Treatment to Promote Smoking Cessation and Survival in Oncology Patients

NCT07166120
View directory record Official record
Conditions
Smoking Cessation, Smoking, Physician's Role
Interventions
Usual care, Precision treatment
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 89 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 29, 2025 · Synced Jul 23, 2026, 6:27 PM EDT
Active, not recruiting Not applicable Interventional

Automated Video-Assisted Smoking Treatment for People Living With HIV

NCT05014282
View directory record Official record
Conditions
Smoking Cessation
Interventions
Nicotine patch, Counseling, Nicotine lozenge, Smartphone-delivered automated treatment
Drug · Behavioral
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older
Enrollment
638 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Feb 8, 2026 · Synced Jul 23, 2026, 6:27 PM EDT
Completed Not applicable Interventional Results available

Smoking Cessation in Menthol Flavored Cigarette Smokers

NCT02342327
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
switch to non-menthol cigarettes prior to cessation attempt, continue smoking menthol cigarettes prior to cessation attempt
Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 64 Years
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 27, 2021 · Synced Jul 23, 2026, 6:27 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Study Evaluating the Absorption Of Varenicline Through The Skin Following Once Daily Application Of A Patch For 14 Days

NCT01234142
View directory record Official record
Conditions
Smoking Cessation
Interventions
varenicline free base patch, placebo patch
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 55 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Fargo, North Dakota
Source: ClinicalTrials.gov public record
Updated Oct 13, 2011 · Synced Jul 23, 2026, 6:27 PM EDT
Completed Not applicable Interventional

Checking Smoking Status as a Routine Vital Sign: A Cluster-Randomized Trial of Its Effect on Cessation Counseling

NCT00245323
View directory record Official record
Conditions
Smoking
Interventions
Smoking status as a routine vital sign
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2014
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Jul 23, 2026, 6:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Integrated Smoking Cessation Treatment for Low Income Community Corrections

NCT01257490
View directory record Official record
Conditions
Smoking Cessation
Interventions
counseling vs. advice
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years to 80 Years
Enrollment
689 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Apr 17, 2017 · Synced Jul 23, 2026, 6:27 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Applying mHealth to Tobacco-related Health Disparities

NCT03404596
View directory record Official record
Conditions
Smoking Cessation
Interventions
Nicotine Patch, Counseling, Smartphone, AutoSense
Drug · Behavioral · Other
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated May 10, 2023 · Synced Jul 23, 2026, 6:27 PM EDT
Recruiting Not applicable Interventional

Technology Assisted Motivational Interviewing

NCT06713603
View directory record Official record
Conditions
Smoking, Smoking Cessation
Interventions
TAMI Coach
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
440 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 22, 2025 · Synced Jul 23, 2026, 6:27 PM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers

Does Moderate Intensity Exercise Help Prevent Smoking Relapse Among Women?

NCT00420160
View directory record Official record
Conditions
Lung Cancer, Heart Disease, COPD
Interventions
Smoking cessation treatment plus moderate intensity exercise, Smoking cessation treatment plus health education
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
59 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Apr 13, 2015 · Synced Jul 23, 2026, 6:27 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Smoking Relapse Prevention Via Just-in-Time-Adaptive Interventions

NCT03690596
View directory record Official record
Conditions
Smoking Cessation
Interventions
NRT + QuitBuddy, NRT + QuitBuddy-Recall, Treatment as Usual
Other
Lead sponsor
Meharry Medical College
Other
Eligibility
18 Years and older
Enrollment
94 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 12, 2021 · Synced Jul 23, 2026, 6:27 PM EDT
Completed Not applicable Interventional Results available

Persistence Targeted Smoking Cessation in Serious Mental Illness (SMI)

NCT03873337
View directory record Official record
Conditions
Tobacco Use, Tobacco Smoking, Tobacco Use Cessation, Tobacco Use Disorder, Schizophrenia, Schizoaffective Disorder
Interventions
Persistence Targeted Smoking Cessation in SMI (PTSC-S), Nicotine patch
Behavioral · Drug
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 70 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 12, 2022 · Synced Jul 23, 2026, 6:27 PM EDT
Completed Not applicable Interventional

Proactive Care Coordination for Cancer Survivors Who Smoke

NCT02723656
View directory record Official record
Conditions
Cancer
Interventions
Online Referral NYS Quitline, Tobacco cessation counseling and coordination of cessation medications
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
581 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 10, 2018 · Synced Jul 23, 2026, 6:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Neuroimaging Studies of Smoking and Treatment

NCT03085602
View directory record Official record
Conditions
Smoking Cessation
Interventions
Cognitive behavioral therapy, Health education
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years to 55 Years
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Apr 15, 2019 · Synced Jul 23, 2026, 6:27 PM EDT
Recruiting Not applicable Interventional

Personalized Tobacco Treatment in Primary Care (MOTIVATE)

NCT05846841
View directory record Official record
Conditions
Physician's Role, Smoking Cessation, Smoking
Interventions
Precision Treatment, Usual Care
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
850 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 8, 2026 · Synced Jul 23, 2026, 6:27 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Varenicline OTC Trial on Efficacy and Safety

NCT03557294
View directory record Official record
Conditions
Tobacco Dependence, Withdrawal Symptoms, Smoking Cessation
Interventions
1.0mg Varenicline b.i.d., 0.5mg Varenicline b.i.d., 0.0mg placebo Varenicline b.i.d.
Drug
Lead sponsor
Arizona State University
Other
Eligibility
21 Years and older
Enrollment
313 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
2
States / cities
Phoenix, Arizona • Burbank, California
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Jul 23, 2026, 6:27 PM EDT