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ClinicalTrials.gov public records Last synced Oct 20, 2026, 6:43 AM EDT

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Showing 385–408 of 2,331 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Smoking Clear all
Withdrawn Not applicable Interventional

Integrated Smoking Cessation and Mood Management for ACS Patients

NCT03029923
View directory record Official record
Conditions
Acute Coronary Syndrome, Tobacco Use
Interventions
Experimental: Behavioral Activation Treatment for Cardiac Smokers (BAT-CS), Smoking cessation plus Health and Wellness
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 29, 2017 · Synced Oct 20, 2026, 6:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Human Laboratory Study Of Varenicline in Smokers

NCT00709696
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Placebo, Varenicline
Drug
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 60 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 27, 2017 · Synced Oct 20, 2026, 6:43 AM EDT
Completed Phase 4 Interventional Results available

PARQuit Smoking Cessation Intervention for Adults With Serious Mental Illness

NCT03950427
View directory record Official record
Conditions
Smoking Cessation, Smoking, Tobacco, Mental Illness, Tobacco Use Disorder
Interventions
Videogame-based physical activity, Sedentary videogame, Bupropion, Counseling
Behavioral · Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 17, 2026 · Synced Oct 20, 2026, 6:43 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Maternal Smoking During Pregnancy and Female Fetal Testosterone Levels

NCT02610751
View directory record Official record
Conditions
Smoking
Interventions
Not listed
Lead sponsor
TriHealth Inc.
Other
Eligibility
18 Years and older · Female only
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
2
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 28, 2019 · Synced Oct 20, 2026, 6:43 AM EDT
Completed No phase listed Observational

Endothelial Progenitor Cells and Risk Factors for Coronary Artery Disease

NCT00013975
View directory record Official record
Conditions
Coronary Arteriosclerosis
Interventions
Not listed
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
Not listed
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2003
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 20, 2026, 6:43 AM EDT
Completed Phase 4 Interventional

Motivation Project: Testing Intervention Components for the Smoker Who is Unwilling to Quit

NCT02354872
View directory record Official record
Conditions
Smoking, Motivation, Smoking Cessation
Interventions
Nicotine Mini-Lozenge, Behavioral Reduction Counseling, 5Rs Motivation Counseling, Behavioral Activation Counseling, No Treatment
Drug · Behavioral · Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
577 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 22, 2020 · Synced Oct 20, 2026, 6:43 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Effects of Smoking, Age and Body Size on Pharmacokinetics, Safety and Tolerability on Tasimelteon in Healthy Subjects

NCT01477619
View directory record Official record
Conditions
Healthy Volunteers
Interventions
Tasimelteon
Drug
Lead sponsor
Vanda Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Springfield, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 17, 2014 · Synced Oct 20, 2026, 6:43 AM EDT
Completed Phase 2 Interventional Results available

Formoterol Dose Ranging Study (ACHIEVE Duaklir USA Phase IIb)

NCT02796651
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease - COPD
Interventions
Formoterol fumarate (6 μg), Formoterol furmarate (20 μg), Placebo for formoterol fumarate, Formoterol fumarate (12 μg), Formoterol fumarate (40 μg)
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
40 Years to 130 Years
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
20
States / cities
Glendale, Arizona • Phoenix, Arizona • Tempe, Arizona + 17 more
Source: ClinicalTrials.gov public record
Updated Feb 7, 2018 · Synced Oct 20, 2026, 6:43 AM EDT
Recruiting Not applicable Interventional

Effects of Novel E-cigarette Constituents on Adults TCORS 3.0

NCT05932745
View directory record Official record
Conditions
Nicotine Use Disorder
Interventions
E-liquid coolant (No WS-3) for non-menthol (1), E-liquid coolant (No WS-3) for low (0.1%) menthol (1), E-liquid coolant (No WS-3) for high (2.0%) menthol (1), E-liquid coolant (Low [0.1%] WS-3) for non-menthol (2), E-liquid coolant (Low [0.1%] WS-3) for low (0.1%) menthol (2), E-liquid coolant (Low [0.1%] WS-3) for high (2.0%) menthol (2), E-liquid coolant (High [2.0%] WS-3) for non-menthol (3), E-liquid coolant (High [2.0%] WS-3) for low (0.1%) menthol (3), E-liquid coolant (High [2.0%] WS-3) for high (2.0%) menthol (3), E-liquid coolant (Low [0.1%] WS-23) for non-menthol (4), E-liquid coolant (Low [0.1%] WS-23) for low (0.1%) menthol (4), E-liquid coolant (Low [0.1%] WS-23) for high (2.0%) menthol (4), E-liquid coolant (High [2.0%] WS-23) for non-menthol (5), E-liquid coolant (High [2.0%] WS-23) for low (0.1%) menthol (5), E-liquid coolant (High [2.0%] WS-23) for high (2.0%) menthol (5), E-liquid coolant (4% WS-23) for non-menthol (6), E-liquid coolant (4% WS-23) for low (0.1%) menthol (6), E-liquid coolant (4% WS-23) for high (2.0%) menthol (6)
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Oct 20, 2026, 6:43 AM EDT
Completed Not applicable Interventional Results available

iQuit Mindfully: Text Messaging for Smoking Cessation

NCT03029819
View directory record Official record
Conditions
Cigarette Smoking
Interventions
Mindfulness-based Addiction Treatment, iQuit Mindfully, Self-Help guide, Nicotine Patch
Behavioral · Drug
Lead sponsor
Georgia State University
Other
Eligibility
18 Years to 65 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 8, 2019 · Synced Oct 20, 2026, 6:43 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Preventing Postpartum Relapse to Smoking Using Yoga and Cognitive Behavioral Therapy: A Randomized Pilot Study

NCT00360581
View directory record Official record
Conditions
Smoking Cessation
Interventions
Yoga, Yoga and Cognitive Behavioral Therapy
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 11, 2008 · Synced Oct 20, 2026, 6:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pittsburgh and Rural Area High School Tobacco Prevention

NCT05081843
View directory record Official record
Conditions
Adolescent Behavior, Tobacco Use, E-Cig Use
Interventions
AD IT UP media literacy intervention, Usual health education curriculum
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
13 Years to 17 Years
Enrollment
318 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Oct 20, 2026, 6:43 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

The Effect of Tobacco Products on Wound Healing

NCT04870970
View directory record Official record
Conditions
Smoking, Tobacco Use, Tobacco Smoking
Interventions
Not listed
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Oct 20, 2026, 6:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cooling Agent Pilot Among Adult Menthol Smokers

NCT06477601
View directory record Official record
Conditions
Tobacco Dependence
Interventions
Assigning cooling agent type cigarettes, Assigning traditional tobacco type cigarettes, Assigning menthol type cigarettes
Other
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
21 Years and older
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 6, 2025 · Synced Oct 20, 2026, 6:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Varenicline-Aided Cigarette Reduction in Smokers Not Ready to Quit

NCT01308736
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
Varenicline, Placebo pill
Drug
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 64 Years
Enrollment
73 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 17, 2017 · Synced Oct 20, 2026, 6:43 AM EDT
Completed Not applicable Interventional Results available

Clinical Trial of Smoking Cessation Mobile Phone Program

NCT02656745
View directory record Official record
Conditions
Nicotine Addiction, Drug Addiction, Drug Dependence, Substance Use Disorder, Tobacco Dependence
Interventions
Mobile Smoking Cessation Solution
Device
Lead sponsor
Click Therapeutics, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
416 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 14, 2018 · Synced Oct 20, 2026, 6:43 AM EDT
Recruiting Not applicable Interventional

PASCAL Feasibility Study

NCT07301151
View directory record Official record
Conditions
Smoking Cessation, Smoking (Tobacco) Addiction
Interventions
chatbot, no chatbot
Other
Lead sponsor
University of Minnesota
Other
Eligibility
21 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Oct 20, 2026, 6:43 AM EDT
Not listed Phase 2Phase 3 Interventional Accepts healthy volunteers

Efficacy and Safety of Combination EMB-001 as a Potential Smoking Cessation Treatment

NCT04868253
View directory record Official record
Conditions
Smoking Cessation, Tobacco Use Disorder
Interventions
EMB-01
Drug
Lead sponsor
Rose Research Center, LLC
Industry
Eligibility
21 Years to 65 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated May 28, 2021 · Synced Oct 20, 2026, 6:43 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

The Study of AZD8529 for Smoking Cessation in Female Smokers

NCT02401022
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
AZD8529
Drug
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years to 75 Years · Female only
Enrollment
214 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
9
States / cities
Encino, California • La Jolla, California • Los Alamitos, California + 6 more
Source: ClinicalTrials.gov public record
Updated Nov 29, 2017 · Synced Oct 20, 2026, 6:43 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Immunosuppressive Effects of Smoking and HIV-1 on the Development of Lung Disease

NCT02058719
View directory record Official record
Conditions
HIV, Smoking, COPD
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 70 Years
Enrollment
210 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 18, 2019 · Synced Oct 20, 2026, 6:43 AM EDT
Recruiting Not applicable Interventional

Impact of Behavior Modification Interventions and Lung Cancer Screening on Smoking Cessation in People Living With HIV: A Feasibility Study

NCT04949464
View directory record Official record
Conditions
HIV Infection, Tobacco-Related Carcinoma
Interventions
Computed Tomography, Smoking Cessation Intervention
Procedure · Behavioral
Lead sponsor
AIDS Malignancy Consortium
Network
Eligibility
45 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
11
States / cities
La Jolla, California • Washington D.C., District of Columbia • Tampa, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 20, 2026, 6:43 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Tobacco Intervention in Buprenorphine Treatment

NCT01350011
View directory record Official record
Conditions
Tobacco Dependence
Interventions
Innovative System, Standard Treatment Control (STC)
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
175 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 13, 2018 · Synced Oct 20, 2026, 6:43 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Linking Brain Network Dynamics to Imminent Smoking Lapse Risk and Behavior

NCT05572671
View directory record Official record
Conditions
Smoking, Tobacco Use
Interventions
Laboratory task modeling smoking lapse behavior
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
21 Years to 65 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Oct 20, 2026, 6:43 AM EDT
Completed Phase 4 Interventional Results available

A Smoking Cessation Intervention for Yale Dining Employees

NCT02562521
View directory record Official record
Conditions
Smoking Cessation
Interventions
Contingency management, Nicotine replacement therapy, Varenicline, Additional behavioral support
Behavioral · Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 9, 2018 · Synced Oct 20, 2026, 6:43 AM EDT