Independent directory Public ClinicalTrials.gov records United States
Clinical Trials Finder
Objective public record navigation
Search Results

Search by objective public record fields.

Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results come from ClinicalTrials.gov. When the live registry is unavailable, a clearly labeled stored copy may be shown.

Clear filters

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Oct 20, 2026, 7:25 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 481–504 of 2,331 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Smoking Clear all
Completed Phase 1 Interventional

Concurrent vs. Sequential Cessation of Dual Cigarette and E-cigarette Use

NCT06027840
View directory record Official record
Conditions
Cigarette Smoking, E-Cigarette Use, Smoking Cessation
Interventions
Varenicline, Counseling, Guided Self-Change Booklets
Drug · Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Oct 20, 2026, 7:25 PM EDT
Completed Not applicable Interventional Results available

Working Memory Training on Delay Discounting Among Cigarette Smokers

NCT05210608
View directory record Official record
Conditions
Tobacco Use Disorder/Cigarette Smoking
Interventions
Working Memory Training + Behavioral Intervention
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 24, 2025 · Synced Oct 20, 2026, 7:25 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluating the Comparative Pharmacokinetics of Nicotine After Administration Via JUUL or Tobacco Cigarettes

NCT04053868
View directory record Official record
Conditions
Nicotine Administration & Dosage, E-cigarettes, Vaping, E-Liquid, Tobacco Smoking
Interventions
JUUL, Tobacco
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years to 70 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
2
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 16, 2025 · Synced Oct 20, 2026, 7:25 PM EDT
Completed Not applicable Interventional Results available

Promotion and Mitigation Factors Leading to Illegal Tobacco Purchases

NCT06001840
View directory record Official record
Conditions
Cigarette Smoking, Nicotine Vaping
Interventions
Promotion factors, Mitigation strategies
Behavioral
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
21 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 10, 2026 · Synced Oct 20, 2026, 7:25 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Comparison of Pharmacokinetic Parameters Between Adopters of Electronic Cigarettes and a Historical Sample of Combustible Cigarette Smokers

NCT02730676
View directory record Official record
Conditions
Smoking
Interventions
Electronic Cigarette #1, Electronic Cigarette #2
Other
Lead sponsor
R.J. Reynolds Vapor Company
Industry
Eligibility
21 Years to 60 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Lakewood, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 1, 2018 · Synced Oct 20, 2026, 7:25 PM EDT
Completed Not applicable Interventional Results available

Telephone Care Coordination for Smokers in VA Mental Health Clinics

NCT00724308
View directory record Official record
Conditions
Smoking
Interventions
Telephone Care Coordination, Telephone Care Coordination with state Quitline
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
577 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 17, 2020 · Synced Oct 20, 2026, 7:25 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Developing Smokers for Smoker (S4S): A Collective Intelligence Tailoring System

NCT02265354
View directory record Official record
Conditions
Tobacco Smoking
Interventions
Collective-Intelligence computer tailored health communication, Rule-based computer tailored health communication
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
19 Years and older
Enrollment
260 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 8, 2020 · Synced Oct 20, 2026, 7:25 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

BAT3221032: A Study to Evaluate the Effects of Switching From Cigarette Smoking to Using One of Five Variants of a Heated Tobacco Product on Biomarkers of Exposure and Biomarkers of Potential Harm in Healthy Subjects

NCT05142436
View directory record Official record
Conditions
Smoking, Tobacco Use, Tobacco Smoking
Interventions
Product A: Non-Combusted Cigarette Variant 42001402 and product use Mode B, Product B: Non-Combusted Cigarette Variant 42001399 and product use Mode B, Product C: Non-Combusted Cigarette Variant 42001401 and product use Mode B, Product D: Non-Combusted Cigarette Variant 40007386 and product use Mode B, Product E: Non-Combusted Cigarette Variant 42001402 and product use Mode A
Other
Lead sponsor
British American Tobacco (Investments) Limited
Industry
Eligibility
26 Years to 55 Years
Enrollment
806 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
18
States / cities
Bentonville, Arkansas • Little Rock, Arkansas • Rogers, Arkansas + 14 more
Source: ClinicalTrials.gov public record
Updated Dec 16, 2022 · Synced Oct 20, 2026, 7:25 PM EDT
Recruiting Not applicable Interventional

Effects of a Low Nicotine Standard and Tobacco Prices on Illegal Cigarette Purchasing

NCT07161050
View directory record Official record
Conditions
Cigarette Smoking, E-cigarette Use
Interventions
Nicotine Content, Illegal cigarette price, E-cigarette price
Behavioral
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
21 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 16, 2026 · Synced Oct 20, 2026, 7:25 PM EDT
Completed Not applicable Interventional Results available

Evaluation of Tobacco Treatment Strategies for Inpatient Psychiatry

NCT00968513
View directory record Official record
Conditions
Tobacco Dependence
Interventions
Brief Intervention, Extended Treatment, Usual Care
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
956 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
3
States / cities
Berkeley, California • San Francisco, California • Stanford, California
Source: ClinicalTrials.gov public record
Updated Jun 11, 2025 · Synced Oct 20, 2026, 7:25 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Tailored Smoking Cessation Intervention in Promoting Sexual and Gender Minority Smokers to Quit Smoking

NCT03669120
View directory record Official record
Conditions
Cigarette Smoker, Current Every Day Smoker
Interventions
Informational Intervention, Telephone-Based Intervention
Other · Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
Not listed
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 2, 2020 · Synced Oct 20, 2026, 7:25 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pilot Study of Nicotine Replacement for Smoking Cessation During Pregnancy

NCT00888979
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
Nicotrol Inhaler
Drug
Lead sponsor
Hartford Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 9, 2017 · Synced Oct 20, 2026, 7:25 PM EDT
Active, not recruiting Phase 1 Interventional Accepts healthy volunteers

Nicotinic Hepatic Metabolism on Neuroreceptor Substrates of Nicotine Addiction

NCT03442413
View directory record Official record
Conditions
Smoking, Tobacco
Interventions
2-[18F]-FA PET/CT, I.V. Nicotine
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 65 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Oct 20, 2026, 7:25 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Naltrexone and Patch for Smokers

NCT00018213
View directory record Official record
Conditions
Smoking
Interventions
Naltrexone Hydrochloride, Transdermal Nicotine
Drug
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
1998 – 2001
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jan 21, 2009 · Synced Oct 20, 2026, 7:25 PM EDT
Completed Phase 4 Interventional Results available

Tobacco Treatment Comparison for Cancer Care

NCT06218823
View directory record Official record
Conditions
Smoking Cessation, Cancer
Interventions
Transdermal Nicotine Patch, Standard Telephone Counseling, Varenicline, Cancer-Targeted Telephone Counseling, Mailed Information about Standard Care Resources
Drug · Behavioral · Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 27, 2025 · Synced Oct 20, 2026, 7:25 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Ketamine and Motivational Enhancement Therapy for the Treatment of Tobacco Use Disorder

NCT05796791
View directory record Official record
Conditions
Tobacco Use, Smoking Cessation, Nicotine Dependence
Interventions
Ketamine Hydrochloride, Motivational enhancement therapy
Drug · Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years to 65 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 18, 2025 · Synced Oct 20, 2026, 7:25 PM EDT
Completed Phase 2 Interventional Results available

A Study to Evaluate the Effect of Lorcaserin Hydrochloride on Smoking Cessation

NCT02044874
View directory record Official record
Conditions
Smoking Cessation
Interventions
APD356-lorcaserin hydrochloride, Placebo
Drug
Lead sponsor
Arena Pharmaceuticals
Industry
Eligibility
18 Years to 65 Years
Enrollment
603 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
31
States / cities
Encino, California • Escondido, California • Los Alamitos, California + 27 more
Source: ClinicalTrials.gov public record
Updated Apr 16, 2019 · Synced Oct 20, 2026, 7:25 PM EDT
Completed Not applicable Interventional

Implementation of a System-level Tobacco Treatment Intervention

NCT02816697
View directory record Official record
Conditions
Smoking Cessation, Lung Cancer
Interventions
CEASE, Usual Care Tobacco Treatment Services
Other
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
263 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Oct 20, 2026, 7:25 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of New Standards for Tobacco Products Among Dual E-Cigarette/Combusted Cigarette Users - Project 2

NCT05473585
View directory record Official record
Conditions
Smoking, Smoking, Cigarette, E-Cig Use, Nicotine Dependence
Interventions
very low nicotine content cigarettes, normal nicotine content cigarettes, Study e-cigarette
Other
Lead sponsor
Duke University
Other
Eligibility
21 Years and older
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 19, 2023 · Synced Oct 20, 2026, 7:25 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Pilot Study to Evaluate the Efficacy of Ariva® Silver Wintergreen, a Smoking Aversive Lozenge

NCT01336816
View directory record Official record
Conditions
Tobacco Use Disorder, Smoking
Interventions
Ariva Silver Wintergreen, Placebo Wintergreen
Other
Lead sponsor
Star Scientific, Inc
Industry
Eligibility
23 Years to 72 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
Martinsburg, West Virginia
Source: ClinicalTrials.gov public record
Updated Oct 24, 2014 · Synced Oct 20, 2026, 7:25 PM EDT
Completed Not applicable Interventional

Feasibility and Efficacy of a Brief Mindfulness-Based Intervention SMOKING INTERVENTION VIA THE INTERNET

NCT04572126
View directory record Official record
Conditions
Substance Use, Smoking Reduction
Interventions
Mindfulness Intervention, Control Intervention
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 11, 2022 · Synced Oct 20, 2026, 7:25 PM EDT
Completed Not applicable Interventional

Quit Smoking Text Message Study

NCT06111755
View directory record Official record
Conditions
Smoking Cessation
Interventions
SmokefreeTXT, Smartband
Other · Device
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
204 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 6, 2025 · Synced Oct 20, 2026, 7:25 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Treating Caregivers Who Smoke at AFCH

NCT06051474
View directory record Official record
Conditions
Smoking, Smoking Cessation
Interventions
Nicotine Replacement Product
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Oct 20, 2026, 7:25 PM EDT
Not listed No phase listed Observational

Perioperative Vaping Complications

NCT05912023
View directory record Official record
Conditions
Vaping, Complication of Anesthesia
Interventions
Not listed
Lead sponsor
Navy Medical Center San Diego
Federal
Eligibility
12 Years to 80 Years
Enrollment
300 participants
Timeline
2023 – 2025
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated May 17, 2024 · Synced Oct 20, 2026, 7:25 PM EDT