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ClinicalTrials.gov public records Last synced Oct 20, 2026, 7:31 PM EDT

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Showing 1–24 of 2,080 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Smoking Behavior Clear all
Completed Not applicable Interventional Results available

SmokefreeSGM, A Text-based Smoking Cessation Feasibility Trial for Sexual and Gender Minority Groups

NCT05645354
View directory record Official record
Conditions
Smoking Cessation
Interventions
SmokefreeSGM, SmokefreeTXT
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 17, 2025 · Synced Oct 20, 2026, 7:31 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Developing and Testing Health Warning Labels on the ENDS Device

NCT04907136
View directory record Official record
Conditions
Electronic Cigarette Use
Interventions
Preferred ENDS, Preferred ENDS with HWL
Other
Lead sponsor
Florida International University
Other
Eligibility
21 Years to 35 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jun 5, 2026 · Synced Oct 20, 2026, 7:31 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Tobacco Intervention in Buprenorphine Treatment

NCT01350011
View directory record Official record
Conditions
Tobacco Dependence
Interventions
Innovative System, Standard Treatment Control (STC)
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
175 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 13, 2018 · Synced Oct 20, 2026, 7:31 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Smoking Response Inhibition Training

NCT02218944
View directory record Official record
Conditions
Smoking Cessation
Interventions
Response Inhibition Training
Behavioral
Lead sponsor
North Dakota State University
Other
Eligibility
18 Years to 45 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Fargo, North Dakota
Source: ClinicalTrials.gov public record
Updated Oct 8, 2014 · Synced Oct 20, 2026, 7:31 PM EDT
Enrolling by invitation Phase 4 Interventional

Piloting Novel Interventional Strategies to Improve Nicotine Pouches as a Substitute for Smoking

NCT07625956
View directory record Official record
Conditions
Smoking ( Cigarette)
Interventions
Nicotine replacement therapy patches, Oral nicotine pouches
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Oct 20, 2026, 7:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Individually Tailored and Integrated Social Support Network for Tobacco Cessation

NCT03152253
View directory record Official record
Conditions
Smoking Cessation
Interventions
Text My Quit (TMQ), Peer Support, Motivational Messages
Behavioral · Other
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years and older
Enrollment
284 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Apr 25, 2019 · Synced Oct 20, 2026, 7:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Hypnosis for Smoking Relapse Prevention

NCT00770380
View directory record Official record
Conditions
Smoking
Interventions
behavioral relapse prevention counseling, hypnosis for relapse prevention
Behavioral · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 80 Years
Enrollment
139 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2011
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 21, 2022 · Synced Oct 20, 2026, 7:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Baby Steps III: Testing a Clinician and Patient Intervention to Promote Smoking Cessation Among Pregnant Women

NCT04985903
View directory record Official record
Conditions
Smoking Cessation, Pregnancy, Communication Research
Interventions
Clinician Communication Intervention, 5A's lecture
Behavioral · Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
414 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 15, 2026 · Synced Oct 20, 2026, 7:31 PM EDT
Recruiting Phase 2 Interventional

Breathe Easier With Tadalafil Therapy for Dyspnea in COPD-PH

NCT05937854
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease, Pulmonary Hypertension, Dyspnea
Interventions
Tadalafil, Placebo
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
35 Years to 89 Years
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
5
States / cities
Aurora, Colorado • Decatur, Georgia • Boston, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated May 15, 2026 · Synced Oct 20, 2026, 7:31 PM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers Results available

Neuro Biomarkers of Smoking Behavior

NCT03811951
View directory record Official record
Conditions
Smoking Cessation
Interventions
Novolin R
Drug
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
21 Years to 40 Years
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 2, 2021 · Synced Oct 20, 2026, 7:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparison of Nicotine Plasma Concentrations and Subjective Effects for Three Menthol Electronic Cigarettes vs Combustible Menthol Cigarettes and Nicotine Gum

NCT02664012
View directory record Official record
Conditions
Smoking
Interventions
Own Brand Menthol Cigarette, Electronic Menthol Cigarette #1, Electronic Menthol Cigarette #2, Electronic Menthol Cigarette #3, Leading U.S. Nicotine Gum
Other
Lead sponsor
R.J. Reynolds Vapor Company
Industry
Eligibility
21 Years to 60 Years
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Lincoln, Nebraska
Source: ClinicalTrials.gov public record
Updated Jun 4, 2018 · Synced Oct 20, 2026, 7:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Human Perception of Odors and Odor Blockers

NCT06191419
View directory record Official record
Conditions
Tobacco Smoking, Smoking Behaviors
Interventions
Odorants
Other
Lead sponsor
Tim McClintock
Other
Eligibility
18 Years to 60 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Oct 20, 2026, 7:31 PM EDT
Completed No phase listed Observational

Endothelial Progenitor Cells and Risk Factors for Coronary Artery Disease

NCT00013975
View directory record Official record
Conditions
Coronary Arteriosclerosis
Interventions
Not listed
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
Not listed
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2003
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 20, 2026, 7:31 PM EDT
Completed Not applicable Interventional Results available

Accelerated Transcranial Magnetic Stimulation (TMS) for Smoking Cessation in People Living With HIV/AIDS (PLWHA)

NCT05295953
View directory record Official record
Conditions
Hiv, Tobacco Smoking
Interventions
TBS, Sham TMS
Device
Lead sponsor
Gopalkumar Rakesh
Other
Eligibility
18 Years to 60 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
2
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Oct 22, 2025 · Synced Oct 20, 2026, 7:31 PM EDT
Completed Phase 3 Interventional

NicVAX/Placebo as an Aid for Smoking Cessation

NCT00836199
View directory record Official record
Conditions
Smoking Cessation, Smoking, Tobacco Cessation
Interventions
NicVAX vaccine, Placebo vaccine
Biological
Lead sponsor
Nabi Biopharmaceuticals
Industry
Eligibility
18 Years to 65 Years
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
22
States / cities
Tucson, Arizona • Los Angeles, California • Newport Beach, California + 19 more
Source: ClinicalTrials.gov public record
Updated May 9, 2012 · Synced Oct 20, 2026, 7:31 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

DECIDE: Developing Tools for Lung Cancer Screening Discussion Improvement

NCT03891602
View directory record Official record
Conditions
Smoking, Smoking, Tobacco, Smoking, Cigarette, Lung Cancer
Interventions
Cataldo Lung Cancer Stigma Scale (Smoking-Related Subscale), Patient Trust in the Medical, Decision Conflict Scale (DCS) - Lung Cancer Screening, Shared Decision Making Questionnaire (SDM-Q)- Patient, Stage of Readiness for Smoking Cessation - Contemplation Ladder, Primary Care Clinicians' Lung Cancer Screening Survey
Behavioral
Lead sponsor
Hackensack Meridian Health
Other
Eligibility
18 Years to 80 Years
Enrollment
654 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 23, 2024 · Synced Oct 20, 2026, 7:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pilot Trial of Using SmokeBeat to Monitor and Increase Smoking Abstinence in Pregnant Women

NCT03209557
View directory record Official record
Conditions
Tobacco Use Cessation, Pregnancy Related
Interventions
SmartWatch SmokeBeat Application
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
Female only
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Lancaster, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 9, 2019 · Synced Oct 20, 2026, 7:31 PM EDT
Completed Phase 2 Interventional

Acute Effects of Exercise in Smokers With Schizophrenia

NCT01635075
View directory record Official record
Conditions
Tobacco Dependence, Cigarette Craving, Smoking Behavior
Interventions
Exercise, passive control
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years to 60 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 28, 2015 · Synced Oct 20, 2026, 7:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Preliminary Test of Reactive Carrot Incentives in a Practice Quit Environment With Contingency Management Incentives

NCT05072301
View directory record Official record
Conditions
Smoking Cessation
Interventions
Contingency Management, Control
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
87 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 1, 2023 · Synced Oct 20, 2026, 7:31 PM EDT
Completed Phase 2 Interventional Results available

Nicotinic Receptors and Schizophrenia

NCT01400477
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder
Interventions
DMXB-A-SR, Placebo
Drug · Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 65 Years
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
2
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated May 7, 2019 · Synced Oct 20, 2026, 7:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

NUYou:mHealth Intervention to Preserve and Promote Ideal Cardiovascular Health

NCT02496728
View directory record Official record
Conditions
Cardiovascular Disease
Interventions
Mobile Health Application, Environmental Cues, Social Support, Educational Materials
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
17 Years to 26 Years
Enrollment
302 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 20, 2019 · Synced Oct 20, 2026, 7:31 PM EDT
Recruiting Not applicable Interventional

Mindfulness-based Ecological Momentary Intervention for Smoking Cessation Among Cancer Survivors

NCT07210567
View directory record Official record
Conditions
Smoking Cessation
Interventions
Mindfulness, Quitline
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Oct 20, 2026, 7:31 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Study to Determine the Effects of ENDS Flavor Availability on Abstinence Within Smokers

NCT07598136
View directory record Official record
Conditions
Smoking, Tobacco
Interventions
P2613422, P2611222, P2615522, P2615122, P2615422
Other
Lead sponsor
RAI Services Company
Industry
Eligibility
21 Years to 65 Years
Enrollment
1,280 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
7
States / cities
Maitland, Florida • Atlanta, Georgia • St Louis, Missouri + 4 more
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Oct 20, 2026, 7:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Characterization of Product Use in Smokers Switching From Cigarettes to a RELX Electronic Nicotine Delivery System

NCT04708106
View directory record Official record
Conditions
Electronic Cigarette Use
Interventions
RELX ENDS Tobacco Flavor, RELX ENDS Menthol Flavor, RELX ENDS Tobacco and Menthol Flavors
Other
Lead sponsor
Cheerain HK Limited
Industry
Eligibility
22 Years to 65 Years
Enrollment
194 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
5
States / cities
Bentonville, Arkansas • Lexington, Kentucky • Springfield, Missouri + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 22, 2021 · Synced Oct 20, 2026, 7:31 PM EDT