Independent directory Public ClinicalTrials.gov records United States
Clear filters

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Oct 21, 2026, 12:40 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 217–240 of 2,080 matching trials from the live ClinicalTrials.gov search.
Conditions
Smoking Cessation, Food Insecurity
Interventions
Quitline Information with Reinforcement
Behavioral
Lead sponsor
Case Western Reserve University
Other
Eligibility
21 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Cleveland, Ohio
Not listed Phase 3 Interventional Accepts healthy volunteers

Yoga for Women Attempting Smoking Cessation

NCT00492310
Conditions
Smoking
Interventions
yoga, cognitive therapy, wellness
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2011
U.S. locations
1
States / cities
Providence, Rhode Island
Completed Not applicable Interventional Accepts healthy volunteers

CONNECT: Smoking Cessation and Lung Cancer Screening

NCT04149249
Conditions
Smoking Cessation
Interventions
Computer-Assisted Intervention Video Doctor, Computer-Assisted Intervention no Video Doctor
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
55 Years to 80 Years
Enrollment
99 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
2
States / cities
San Francisco, California
Completed Not applicable Interventional Accepts healthy volunteers

CSD231005 Nicotine Pouch Biomarkers of Exposure

NCT06303115
Conditions
Tobacco Use, Smoking
Interventions
Nicotine Pouch P1312914, 4 mg nicotine, Nicotine Pouch P1312915, 8 mg nicotine, Nicotine Pouch P1013215, 8 mg nicotine, Nicotine Pouch P1013218, 10 mg nicotine, Nicotine Pouch P1012919, 12 mg nicotine, Smoking Abstinence, Continued UB cigarette smoking
Other
Lead sponsor
RAI Services Company
Industry
Eligibility
21 Years to 60 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
5
States / cities
Bentonville, Arkansas • Lexington, Kentucky • Springfield, Missouri + 2 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Tobacco Treatment in the Context of Lung Cancer Screening

NCT03927989
Conditions
Smoking Cessation
Interventions
Text messaging plus nicotine replacement therapy, Standard Care at Lung Cancer Screening
Behavioral · Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
55 Years and older
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Charleston, South Carolina
Conditions
Hypertension, Diabetes, Sedentary Behavior, High Cholesterol, Diet, Healthy, Smoking Reduction, Weight Loss
Interventions
Physical Activity and Education Intervention
Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older · Male only
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Columbus, Ohio
Completed Not applicable Interventional Accepts healthy volunteers Results available

Smokers' Response to Nicotine Dependence Genotyping

NCT01780038
Conditions
Cigarette Smoking, Nicotine Dependence
Interventions
Receipt of Genetic Results, No results given
Behavioral
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Omaha, Nebraska
Completed Phase 4 Interventional Results available

A Text Messaging Program for Smokers in Primary Care

NCT03174158
Conditions
Smoking Cessation
Interventions
Mailed nicotine replacement therapy, Text messaging, Brief advice
Drug · Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Smoking
Interventions
Counseling, Chiropractic adjustment
Behavioral · Procedure
Lead sponsor
Southern California University of Health Sciences
Other
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Whittier, California
Active, not recruiting Phase 2 Interventional Accepts healthy volunteers

Mobile App for Smoking Cessation and Mental Health

NCT04887558
Conditions
Smoking Cessation, Mental Illness
Interventions
Smart-T Mental Health+ and NRT, QuitGuide + NRT
Combination Product
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 100 Years
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2028
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Conditions
Smoking Reduction, Smoking Behaviors
Interventions
Repetitive transcranial magnetic stimulation (rTMS)
Device
Lead sponsor
West Virginia University
Other
Eligibility
18 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Morgantown, West Virginia
Completed Phase 1 Interventional Results available

New Approaches to Smoking Cessation in Heavy Drinkers

NCT02151591
Conditions
Nicotine Dependence, Cigarette Smoking, Alcohol Consumption, Heavy Drinking
Interventions
Varenicline
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 75 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
New Haven, Connecticut
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Effect of Helpers Program On-line Training on Smoking Relapse and Social Networks

NCT05641974
Conditions
Smoking, Cigarette Smoking
Interventions
Helpers Stay Quit Training
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 99 Years
Enrollment
940 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Aurora, Colorado
Completed Not applicable Interventional Results available

Learn to Quit-HIV Pilot Study

NCT04609514
Conditions
HIV/AIDS, Smoking Cessation, Tobacco Use Disorder
Interventions
Learn to Quit-HIV, QuitGuide, Nicotine patch, Smartphone coaching
Device · Behavioral · Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Completed No phase listed Observational Accepts healthy volunteers

Clinical Learning Study for a Mobile Smoking Cessation Program

NCT04857515
Conditions
Smoking Cessation, Smoking Behaviors, Smoking Reduction, Smoking, Cigarette, Smoking, Nicotine Dependence
Interventions
Clickotine®
Device
Lead sponsor
Click Therapeutics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Accepts healthy volunteers

Inspired: Smartphone Videogame-Based Smoking Cessation Intervention

NCT03929003
Conditions
Smoking Cessation
Interventions
Inspired
Behavioral
Lead sponsor
Rowan University
Other
Eligibility
18 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Glassboro, New Jersey
Conditions
Smoking Cessation
Interventions
Distress Tolerance Treatment for Weight Concern (DT-W), Health Education (HE)
Behavioral
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Providence, Rhode Island
Conditions
Cigarette Smoking, Drug Use
Interventions
Standard Treatment, BAD-AS, Transdermal Nicotine Patch
Behavioral · Drug
Lead sponsor
University of Maryland, College Park
Other
Eligibility
18 Years to 65 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Conditions
Tobacco Use Disorder
Interventions
Memantine
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
21 Years to 45 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
New York, New York
Recruiting Not applicable Interventional Accepts healthy volunteers

The Impact of Menthol Flavoring on Switching in Adult Menthol Smokers

NCT05555069
Conditions
Smoking Reduction
Interventions
Menthol-flavored electronic cigarette, Tobacco-flavored electronic cigarette
Other
Lead sponsor
Nikki Nollen, PhD, MA
Other
Eligibility
21 Years and older
Enrollment
800 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Kansas City, Missouri
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Innovative Interventions for Smoking Cessation

NCT01050569
Conditions
Tobacco Use Disorder
Interventions
Nicotine Patch, VLNC Cigarette, VLNC Cigarette Plus Nicotine Patch
Drug · Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
235 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
2
States / cities
Duluth, Minnesota • Minneapolis, Minnesota
Conditions
Alcoholism, Smoking
Interventions
nicotine replacement patch
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years and older
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2002
U.S. locations
1
States / cities
West Haven, Connecticut
Conditions
Veterans, Tobacco Use Disorder, Cigarette Smoking, Tobacco Dependence
Interventions
Motivation-Phase Varenicline, Motivation-Phase Nicotine Mini-Lozenge, Cessation-Phase Combination Nicotine Replacement Therapy (NRT), Cessation-Phase Varenicline, Motivation-Phase Counseling, Cessation-Phase Counseling
Drug · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
4
States / cities
San Diego, California • Minneapolis, Minnesota • Durham, North Carolina + 1 more
Completed Not applicable Interventional Results available

A Quit Smoking Study Using Smartphones

NCT02164383
Conditions
Smoking Cessation, Smoking, Nicotine Dependence
Interventions
Nicotine patch, Cessation Counseling, Mobile Games
Drug · Behavioral · Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Madison, Wisconsin