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ClinicalTrials.gov public records Last synced Oct 22, 2026, 7:56 PM EDT

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Showing 505–528 of 2,080 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Smoking Behavior Clear all
Completed Not applicable Interventional

Prevention of Postpartum Smoking Relapse in Mothers of Infants in the Neonatal Intensive Care Unit (NICU)

NCT01131156
View directory record Official record
Conditions
Smoking
Interventions
Smoking Relapse Prevention
Behavioral
Lead sponsor
Loma Linda University
Other
Eligibility
Up to 1 Week
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated May 14, 2014 · Synced Oct 22, 2026, 7:56 PM EDT
Completed No phase listed Observational

A Mood Management Intervention for Pregnant Smokers

NCT00505869
View directory record Official record
Conditions
Pregnancy, Smoking
Interventions
Health & Wellness Intervention, Questionnaire, Mood Management Intervention
Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
16 Years and older · Female only
Enrollment
338 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 2, 2012 · Synced Oct 22, 2026, 7:56 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Brain/Craving Response to Smoking Cues After Oral Nicotine Pouch Use

NCT07698470
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Oral Nicotine Pouch, Smoking Cue Reactivity Task
Other · Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
21 Years to 55 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Oct 22, 2026, 7:56 PM EDT
Recruiting Phase 3 Interventional Accepts healthy volunteers

Integrating Financial Coaching and Smoking Cessation Coaching

NCT05154669
View directory record Official record
Conditions
Smoking
Interventions
Financial counseling, Nicotine Replacement Therapy Agent - Patches, Nicotine Replacement Therapy Agent - Lozenges, Nicotine Replacement Therapy Agent - Gum
Other · Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 100 Years
Enrollment
602 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2029
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Oct 22, 2026, 7:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Prize Reinforcement for Smoking Cessation

NCT00865254
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Standard Treatment, Traditional Contingency Management, Early Enhanced Contingency Management
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
13 Years and older
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2011
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 28, 2013 · Synced Oct 22, 2026, 7:56 PM EDT
Withdrawn Phase 2 Interventional Accepts healthy volunteers

Effects of Nicotine Replacement Therapy and D-cycloserine on Nicotine Treatment Seekers

NCT01907594
View directory record Official record
Conditions
Cigarette Smoking
Interventions
D-cycloserine, Nicotine Replacement Therapy (patch), Smoking Cue Exposure, Progressive Muscle Relaxation, Placebo
Drug · Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
21 Years to 55 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 8, 2020 · Synced Oct 22, 2026, 7:56 PM EDT
Recruiting Not applicable Interventional

Cessation of Dual Use of Cigarettes and E-cigarettes During Pregnancy

NCT07124702
View directory record Official record
Conditions
Dual Use of Cigarettes and E-cigarettes, Gestational Weight Gain, Birth-weight-for-gestational-age z Score
Interventions
Simultaneous cessation intervention, Stepwise cessation intervention, Behavior counseling only
Behavioral
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years and older · Female only
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Nov 13, 2025 · Synced Oct 22, 2026, 7:56 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

E-Cigarettes: Dynamic Patterns of Use and Health Effects

NCT02527980
View directory record Official record
Conditions
Smoking, Nicotine Dependence
Interventions
No intervention: observation only
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 99 Years
Enrollment
422 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
2
States / cities
Madison, Wisconsin • Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 10, 2019 · Synced Oct 22, 2026, 7:56 PM EDT
Completed Phase 3 Interventional Results available

A Second Study of Cytisinicline for Smoking Cessation in Adult Smokers

NCT05206370
View directory record Official record
Conditions
Smoking Cessation
Interventions
Cytisinicline, Placebo, Behavioral support
Drug · Behavioral
Lead sponsor
Achieve Life Sciences
Industry
Eligibility
18 Years and older
Enrollment
792 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
12
States / cities
DeLand, Florida • Fort Myers, Florida • Jacksonville, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Jan 14, 2026 · Synced Oct 22, 2026, 7:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mobile Mindfulness Training for Smoking Cessation

NCT02037360
View directory record Official record
Conditions
Smoking Cessation
Interventions
Active Comparator App/Training, Experimental App/Training
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years to 65 Years
Enrollment
1,251 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 30, 2018 · Synced Oct 22, 2026, 7:56 PM EDT
Completed Phase 3 Interventional Results available

Concurrent Bupropion / Varenicline for Smoking Cessation

NCT01303861
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Varenicline, Bupropion, Nicotine patches, Nicotine Inhaler
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 65 Years
Enrollment
702 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
4
States / cities
Charlotte, North Carolina • Durham, North Carolina • Raleigh, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 6, 2014 · Synced Oct 22, 2026, 7:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Developing E-liquid Product Standards (Sweet Spot Study)

NCT05864586
View directory record Official record
Conditions
Nicotine, Nicotine Vaping, E-cigarette Use
Interventions
Vaping study EC A, Vaping study EC B, Vaping study EC C, Vaping study EC D, Vaping study EC E, Vaping study EC F, Vaping study EC G, Vaping study EC H, Vaping study EC I, Vaping study EC J
Behavioral
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
21 Years to 50 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 10, 2025 · Synced Oct 22, 2026, 7:56 PM EDT
Active, not recruiting Not applicable Interventional

A Pragmatic Trial of Chronic Disease Approaches to Ameliorate Tobacco Related Cardiovascular Disease Health Disparities

NCT05671380
View directory record Official record
Conditions
Tobacco Use Cessation, Cardiovascular Diseases, Tobacco Use, Smoking, Smoking Cessation
Interventions
Longitudinal Proactive Outreach (LPO)., Ask-Advice-Connect (AAC)
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
700 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
3
States / cities
Minneapolis, Minnesota • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 22, 2026, 7:56 PM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

Effect of Cannabis on Cigarette Use Behavior

NCT06609083
View directory record Official record
Conditions
Cannabis Use, Tobacco Use, Cigarette Smoking
Interventions
THC 30mg, THC 5mg, THC 0mg, Cigarette Full Nicotine, Cigarette Reduced Nicotine
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 16, 2026 · Synced Oct 22, 2026, 7:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Strategies to Promote Cessation in Smokers Who Are Not Ready To Quit

NCT02905656
View directory record Official record
Conditions
Smoking Cessation
Interventions
Brief Advice, Motivational Interviewing, Rate Reduction, Pharmacological, MI+RR
Behavioral · Drug
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
903 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 1, 2024 · Synced Oct 22, 2026, 7:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Assessment of Two New Electronic Cigarettes in Cigarette Smokers

NCT03435562
View directory record Official record
Conditions
Electronic Cigarettes
Interventions
JUUL electronic cigarette, IQOS electronic cigarette, Own Brand cigarette
Other
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
21 Years to 55 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 3, 2020 · Synced Oct 22, 2026, 7:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Inspired: Smartphone Videogame-Based Smoking Cessation Intervention

NCT03929003
View directory record Official record
Conditions
Smoking Cessation
Interventions
Inspired
Behavioral
Lead sponsor
Rowan University
Other
Eligibility
18 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Glassboro, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 10, 2020 · Synced Oct 22, 2026, 7:56 PM EDT
Completed Phase 4 Interventional

Varenicline Treatment in Alcohol and Nicotine Dependent Patients With Schizophrenia

NCT00727103
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder, Alcohol Dependence, Nicotine Dependence
Interventions
Varenicline, Placebo
Drug
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
18 Years to 69 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Feb 8, 2024 · Synced Oct 22, 2026, 7:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Smartphone Application (ACT on Vaping) for Vaping Cessation in Young Adults

NCT05897242
View directory record Official record
Conditions
Nicotine Dependence, Nicotine Addiction, Nicotine Use Disorder, Nicotine Vaping, Vaping
Interventions
Smartphone app, Text Message, Survey Administration
Behavioral · Other
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years to 30 Years
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 24, 2025 · Synced Oct 22, 2026, 7:56 PM EDT
Completed No phase listed Observational

Impact of Lung Cancer Diagnosis on Relatives' Understanding of Genetic Risk and Receptivity to Quit Smoking

NCT00341341
View directory record Official record
Conditions
Lung Cancer
Interventions
Not listed
Lead sponsor
National Human Genome Research Institute (NHGRI)
NIH
Eligibility
18 Years to 55 Years
Enrollment
757 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 22, 2026, 7:56 PM EDT
Completed Not applicable Interventional Results available

Internet-Administered Smoking Cessation Treatment for Overweight and Obese Smokers

NCT01259466
View directory record Official record
Conditions
Smoking Cessation, Overweight, Obesity
Interventions
Nicotine patch
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 28, 2015 · Synced Oct 22, 2026, 7:56 PM EDT
Completed Not applicable Interventional

System Based Tracking and Treatment for Emergency Patients Who Smoke: STTEPS

NCT01839903
View directory record Official record
Conditions
Tobacco Dependence
Interventions
EDIS, Care as usual
Other
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years and older
Enrollment
444 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
2
States / cities
Worcester, Massachusetts • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Apr 25, 2019 · Synced Oct 22, 2026, 7:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Behavioral Smoking Cessation Treatment - 1

NCT00110825
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
Cognitive Behavior Therapy
Behavioral
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years to 65 Years
Enrollment
304 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2009
U.S. locations
1
States / cities
San Jose, California
Source: ClinicalTrials.gov public record
Updated Jan 12, 2017 · Synced Oct 22, 2026, 7:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Intervention Study to Increase Smoking Cessation Rates Among Public Housing Residents

NCT01651611
View directory record Official record
Conditions
Tobacco Cessation
Interventions
Motivational interviewing, Smoking cessation counseling, Navigation to smoking cessation resources, Social support
Behavioral
Lead sponsor
Boston University
Other
Eligibility
18 Years to 79 Years
Enrollment
330 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 29, 2016 · Synced Oct 22, 2026, 7:56 PM EDT