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ClinicalTrials.gov public records Last synced Oct 22, 2026, 10:38 PM EDT

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Showing 553–576 of 2,080 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Smoking Behavior Clear all
Completed No phase listed Observational

A Focus Group Study to Explore Smoking Triggers and Acceptability of Just-in-time Adaptive Intervent

NCT05231421
View directory record Official record
Conditions
Smoking, Smoking Cessation, Smoking Behaviors
Interventions
Focus Group
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 89 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 7, 2025 · Synced Oct 22, 2026, 10:38 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Effectiveness of Various Smoking Cessation Therapies in Reducing Smoking in Adolescents - 1

NCT00158171
View directory record Official record
Conditions
Smoking Cessation, Tobacco Use Disorder
Interventions
Nicotine Replacement Therapies, Nicotine patch, Folic Acid
Drug · Dietary Supplement
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
13 Years to 18 Years
Enrollment
128 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2004
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 10, 2017 · Synced Oct 22, 2026, 10:38 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Collection of Airway, Blood and/or Urine Specimens From Subjects for Research Studies

NCT01776398
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease (COPD), Smoking, Smoking Cessation, Idiopathic Pulmonary Fibrosis (IPF), Rheumatoid Arthritis-Associated Interstitial Lung Disease, Scleroderma-Associated Interstitial Lung Disease (SSC-ILD)
Interventions
Not listed
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
2,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 14, 2025 · Synced Oct 22, 2026, 10:38 PM EDT
Completed Early Phase 1 Interventional Results available

Imaging the Neurochemistry of Drug Addiction With PET

NCT02817698
View directory record Official record
Conditions
Smoking, Cannabis
Interventions
cannabis
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 55 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
3
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Dec 12, 2024 · Synced Oct 22, 2026, 10:38 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Effects of Nicotine Reduction on Smoking Behavior in ADHD Smokers

NCT02599571
View directory record Official record
Conditions
Nicotine Dependence, ADHD
Interventions
Very low nicotine content cigarettes, Conventional nicotine content cigarettes
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years to 40 Years
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
2
States / cities
Durham, North Carolina • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 27, 2020 · Synced Oct 22, 2026, 10:38 PM EDT
Completed Not applicable Interventional Results available

Behavioral Activation for Smoking Cessation and the Prevention of Post-Cessation Weight Gain

NCT02906787
View directory record Official record
Conditions
Smoking Cessation, Weight Loss
Interventions
BAS+, SC
Behavioral
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
288 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 29, 2024 · Synced Oct 22, 2026, 10:38 PM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Preloading With Nicotine Replacement Therapy in HIV-positive Smokers to Improve Self-Efficacy and Quit Attempts

NCT04994444
View directory record Official record
Conditions
Tobacco Use Cessation
Interventions
Nicoderm CQ 21Mg/24Hr Transdermal System
Drug
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Apr 6, 2025 · Synced Oct 22, 2026, 10:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Empowering LGBTQ+ Tobacco Cessation Pilot

NCT05365633
View directory record Official record
Conditions
Smoking Cessation
Interventions
Empowerment activity-enhanced tobacco cessation assistance
Behavioral
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated May 15, 2025 · Synced Oct 22, 2026, 10:38 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

HIV+ Alveolar Macrophage Oxidant-mediated Apoptosis of Pulmonary Endothelium

NCT02056158
View directory record Official record
Conditions
HIV, COPD, Emphysema, Smoking
Interventions
Not listed
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 22, 2021 · Synced Oct 22, 2026, 10:38 PM EDT
Completed Phase 3 Interventional

A Twelve-Week Study of Varenicline for Safety and Efficacy in Comparison With Placebo and Zyban for Smoking Cessation

NCT00141206
View directory record Official record
Conditions
Smoking Cessation
Interventions
varenicline (CP-526,555)
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 75 Years
Enrollment
1,005 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
20
States / cities
Tucson, Arizona • Los Angeles, California • Newport Beach, California + 17 more
Source: ClinicalTrials.gov public record
Updated Jun 4, 2007 · Synced Oct 22, 2026, 10:38 PM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers Results available

Laboratory Screening of Lorcaserin for Alcohol Use Disorder

NCT04396847
View directory record Official record
Conditions
Alcohol Use Disorder, Tobacco Smoking
Interventions
Lorcaserin Oral Tablet, Placebo oral tablet
Drug
Lead sponsor
The Mind Research Network
Other
Eligibility
21 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Sep 7, 2022 · Synced Oct 22, 2026, 10:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Quit4Baby Evaluation

NCT02412865
View directory record Official record
Conditions
Smoking Cessation, Pregnancy
Interventions
Quit4Baby, Text4Baby
Behavioral
Lead sponsor
George Washington University
Other
Eligibility
14 Years to 44 Years · Female only
Enrollment
505 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2015
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Feb 26, 2016 · Synced Oct 22, 2026, 10:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

CSD170401: Study to Assess Elements of Abuse Liability for Three Electronic Tobacco Vapor Products During an 11-Day In-Clinic Confinement

NCT03126357
View directory record Official record
Conditions
Smoking
Interventions
Product A, Product B, Product C, Product D, Product E
Other
Lead sponsor
RAI Services Company
Industry
Eligibility
21 Years to 60 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Lincoln, Nebraska
Source: ClinicalTrials.gov public record
Updated Jun 27, 2017 · Synced Oct 22, 2026, 10:38 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Quitxt Mobile Text Messaging Cessation Research Study

NCT05958667
View directory record Official record
Conditions
Smoking Cessation
Interventions
Quitxt text messaging or Chat, Usual care
Behavioral · Other
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 29 Years
Enrollment
1,200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Oct 22, 2026, 10:38 PM EDT
Not yet recruiting Not applicable Interventional

Quit With Sense: Using Mindful Smoking and Wearable Device for Smoking Cessation

NCT07789496
View directory record Official record
Conditions
Smoking Cessation, Cigarette Smoking, Tobacco Use, Nicotine Dependence
Interventions
Mindful Smoking and Sensor-Band Intervention, Smoking Cessation Information
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 22, 2026, 10:38 PM EDT
Withdrawn Phase 4 Interventional

Effects of Varenicline in Heavy Drinking Smokers

NCT02488889
View directory record Official record
Conditions
Cigarette Smoking, Alcohol Consumption
Interventions
Varenicline, Placebo pill (for varenicline), Alcohol, placebo beverage (for alcohol)
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
21 Years to 55 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 1, 2018 · Synced Oct 22, 2026, 10:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of E-Liquid Flavor on Respiratory Symptoms in People Using Electronic Nicotine Delivery Systems

NCT05423340
View directory record Official record
Conditions
Electronic Cigarette Use
Interventions
E-cigarette Flavor, Tobacco Free Nicotine Pouch
Other
Lead sponsor
Roswell Park Cancer Institute
Other
Eligibility
21 Years to 55 Years
Enrollment
163 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Oct 22, 2026, 10:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Smoker-to-Smoker (S2S) Peer Marketing and Messaging to Disseminate Tobacco Interventions

NCT03224520
View directory record Official record
Conditions
Smoking Cessation
Interventions
Recommender CTHC, Standard CTHC, Peer Recruitment, Standard Online Recruitment
Behavioral · Other
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
1,487 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 26, 2021 · Synced Oct 22, 2026, 10:38 PM EDT
Completed Phase 2Phase 3 Interventional

Tobacco Use in Opioid Agonist Treated Pregnant Women

NCT00497068
View directory record Official record
Conditions
Nicotine Dependence
Interventions
tobacco abstinent contingent, non-contingent, control
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 5, 2013 · Synced Oct 22, 2026, 10:38 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Informing Tobacco Treatment Guidelines for African American Non-Daily Smokers

NCT02244918
View directory record Official record
Conditions
Smoking Cessation
Interventions
Nicotine Replacement Therapy, Smoking Cessation Counseling
Drug · Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older
Enrollment
278 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
2
States / cities
Kansas City, Kansas • Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 9, 2019 · Synced Oct 22, 2026, 10:38 PM EDT
Completed Not applicable Interventional

Pediatric Emergency Department Decision Support System to Reduce Secondhand Smoke

NCT02489708
View directory record Official record
Conditions
Asthma, Smoking Cessation
Interventions
Cessation Counseling
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
1 Day and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 9, 2021 · Synced Oct 22, 2026, 10:38 PM EDT
Not listed Phase 3 Interventional Accepts healthy volunteers

Yoga for Women Attempting Smoking Cessation

NCT00492310
View directory record Official record
Conditions
Smoking
Interventions
yoga, cognitive therapy, wellness
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2011
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 20, 2010 · Synced Oct 22, 2026, 10:38 PM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers

Exercise to Enhance Smoking Cessation for Women at the YMCA

NCT01615380
View directory record Official record
Conditions
Smoking
Interventions
CBT+ Contact, CBT+ Exercise
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
408 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2012
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 8, 2012 · Synced Oct 22, 2026, 10:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

IQOS (Non-Cigarette Tobacco Product) Pilot Study

NCT04357379
View directory record Official record
Conditions
Smoking, Tobacco Use
Interventions
IQOS
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 27, 2021 · Synced Oct 22, 2026, 10:38 PM EDT