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ClinicalTrials.gov public records Last synced Oct 24, 2026, 8:34 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 937–960 of 2,080 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Smoking Behavior Clear all
Completed Not applicable Interventional

Construal Level as a Novel Pathway for Affect Regulation and Cancer Control

NCT04620915
View directory record Official record
Conditions
Smoking Cessation, Smoking Reduction, Cancer
Interventions
High-level construal, Down-regulation of craving for cigarettes, Up-regulation of goal energization
Behavioral
Lead sponsor
University of Oregon
Other
Eligibility
25 Years to 55 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
2
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Oct 24, 2026, 8:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Preventing Postpartum Return to Smoking

NCT00917943
View directory record Official record
Conditions
Smoking
Interventions
Tailored Counseling Intervention Arm
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older · Female only
Enrollment
386 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 10, 2013 · Synced Oct 24, 2026, 8:34 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Nicotine and Brain Imaging Research Study

NCT01227343
View directory record Official record
Conditions
Nicotine
Interventions
Not listed
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 50 Years
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 4, 2021 · Synced Oct 24, 2026, 8:34 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Comparison of Low Yield Cigarettes in African Americans vs. Whites

NCT01058876
View directory record Official record
Conditions
Cigarette Smoking
Interventions
Deuterated nicotine and cotinine
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 65 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 24, 2013 · Synced Oct 24, 2026, 8:34 PM EDT
Recruiting Not applicable Interventional

Testing the mHealth App Intervention for Nondaily Smokers "SiS4"

NCT06678243
View directory record Official record
Conditions
Smoking Cessation
Interventions
Smiling instead of Smoking, QuitGuide
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
1,600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 24, 2026, 8:34 PM EDT
Completed Not applicable Interventional Results available

Testing an Organizational Change Model to Address Smoking in Mental Healthcare

NCT02849652
View directory record Official record
Conditions
Nicotine Dependence
Interventions
ATTOC Intervention, UC Intervention
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 99 Years
Enrollment
832 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 21, 2023 · Synced Oct 24, 2026, 8:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Helping Moms Quit Pilot Trial

NCT05041413
View directory record Official record
Conditions
Smoking Cessation
Interventions
Moms Quit, Text4Baby
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Nov 4, 2022 · Synced Oct 24, 2026, 8:34 PM EDT
Completed Not applicable Interventional Results available

CoQuit Study for Smoking Cessation

NCT04893460
View directory record Official record
Conditions
Smoking Cessation
Interventions
CoQuit App
Behavioral
Lead sponsor
Oregon Research Behavioral Intervention Strategies, Inc.
Industry
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Springfield, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 4, 2025 · Synced Oct 24, 2026, 8:34 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Adaptation and Initial Evaluation of Transdiagnostic CBT for Anxious and Depressed Smokers

NCT03920137
View directory record Official record
Conditions
Smoking Cessation
Interventions
UP-ST Therapy, Standard Therapy, Nicotine Patch
Behavioral · Device
Lead sponsor
University of Houston
Other
Eligibility
18 Years to 65 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 13, 2023 · Synced Oct 24, 2026, 8:34 PM EDT
Completed Not applicable Interventional Results available

Study of Mood Effects of Varenicline (Chantix) in Depressed Outpatient Smokers

NCT00525837
View directory record Official record
Conditions
Depressive Disorder, Smoking
Interventions
fixed dose varenicline, varenicline
Drug
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Nov 28, 2018 · Synced Oct 24, 2026, 8:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Motivation and Skills for Delta-9-tetrahydrocannabinol/Ethanol (THC/ETOH+) Teens in Jail

NCT00506753
View directory record Official record
Conditions
Alcohol Drinking, Marijuana Smoking
Interventions
MI/CBT, RT/SU
Behavioral
Lead sponsor
University of Rhode Island
Other
Eligibility
14 Years to 19 Years
Enrollment
205 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2011
U.S. locations
1
States / cities
Cranston, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 15, 2019 · Synced Oct 24, 2026, 8:34 PM EDT
Completed Phase 3 Interventional

Safety and Efficacy Study of Topiramate to Aid in Smoking Cessation

NCT00280839
View directory record Official record
Conditions
Smoking Cessation
Interventions
Topiramate, Placebo
Drug
Lead sponsor
Lindner Center of HOPE
Other
Eligibility
18 Years to 65 Years
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 13, 2012 · Synced Oct 24, 2026, 8:34 PM EDT
Completed Not applicable Interventional

Technology and Telephone-Based Smoking Cessation

NCT03492645
View directory record Official record
Conditions
Smoking Cessation
Interventions
Telephone-and technology-facilitated treatment protocol, Office-based treatment protocol
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 69 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 30, 2019 · Synced Oct 24, 2026, 8:34 PM EDT
Completed Not applicable Interventional

An Exercise App to Reduce Young Adults' MJ Use

NCT01863095
View directory record Official record
Conditions
Marijuana Smoking
Interventions
Personalized Feedback and Exercise
Behavioral
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years to 25 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Feb 1, 2016 · Synced Oct 24, 2026, 8:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Examination of Low Wattage and High Wattage E-Cigarettes

NCT03113136
View directory record Official record
Conditions
Smoking, Cigarette, Smoking, Tobacco, Nicotine Dependence, Exposure to Toxic Agent
Interventions
Low wattage E cigarette device, High wattage E cigarette device, Usual brand cigarette
Behavioral
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years to 99 Years
Enrollment
372 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 17, 2026 · Synced Oct 24, 2026, 8:34 PM EDT
Completed No phase listed Observational

Biobank for African American Prostate Cancer Research in Florida

NCT03232411
View directory record Official record
Conditions
Prostate Cancer
Interventions
Questionnaires, Saliva Samples, Tumor Tissue
Other
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
20 Years and older · Male only
Enrollment
592 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Dec 4, 2025 · Synced Oct 24, 2026, 8:34 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Rural Smoking Cessation

NCT06584929
View directory record Official record
Conditions
Smoking Cessation
Interventions
Nicoderm CQ nicotine patch, Nicorette Nicotine Lozenges
Drug
Lead sponsor
Masonic Cancer Center, University of Minnesota
Other
Eligibility
21 Years and older
Enrollment
544 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Oct 24, 2026, 8:34 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Brain Circuits in Schizophrenia and Smoking

NCT01369966
View directory record Official record
Conditions
Schizophrenia, Smoking Cessation, Nicotine Abuse
Interventions
Not listed
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years to 62 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Catonsville, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 5, 2018 · Synced Oct 24, 2026, 8:34 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Evaluation of An Oral Fluid Collection Device

NCT02026440
View directory record Official record
Conditions
Smoking
Interventions
Not listed
Lead sponsor
Avioq, Inc.
Industry
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Research Triangle Park, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 3, 2014 · Synced Oct 24, 2026, 8:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Telephone-Delivered Interventions for Smoking Cessation

NCT02421991
View directory record Official record
Conditions
Smoking
Interventions
Telephone Delivered Intervention
Behavioral
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
1,275 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 21, 2020 · Synced Oct 24, 2026, 8:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of E-Liquid Flavor on Respiratory Symptoms in People Using Electronic Nicotine Delivery Systems

NCT05423340
View directory record Official record
Conditions
Electronic Cigarette Use
Interventions
E-cigarette Flavor, Tobacco Free Nicotine Pouch
Other
Lead sponsor
Roswell Park Cancer Institute
Other
Eligibility
21 Years to 55 Years
Enrollment
163 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Oct 24, 2026, 8:34 PM EDT
Recruiting Not applicable Interventional

E-cigarettes for Harm Reduction Among Smokers With Serious Mental Illness

NCT05815199
View directory record Official record
Conditions
Cigarette Smoking
Interventions
E-cigarette (EC), Nicotine Replacement Therapy (NRT), Harm-Reduction Counseling, Ecological Momentary Intervention (EMI) Text Messaging
Other · Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
21 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 29, 2026 · Synced Oct 24, 2026, 8:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Responses of Adults Smoking Nondaily and Daily in the Experimental Tobacco Marketplace

NCT06988371
View directory record Official record
Conditions
Tobacco Use, Cigarette Use
Interventions
Reduced nicotine regulatory environment, Restriction on characterizing flavors in combustible nicotine products, Restriction on characterizing flavors in noncombustible nicotine products
Behavioral
Lead sponsor
Bethany Shorey Fennell, PhD
Other
Eligibility
18 Years and older
Enrollment
747 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 24, 2026, 8:34 PM EDT
Withdrawn Phase 4 Interventional

Effects of Varenicline in Heavy Drinking Smokers

NCT02488889
View directory record Official record
Conditions
Cigarette Smoking, Alcohol Consumption
Interventions
Varenicline, Placebo pill (for varenicline), Alcohol, placebo beverage (for alcohol)
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
21 Years to 55 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 1, 2018 · Synced Oct 24, 2026, 8:34 PM EDT