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ClinicalTrials.gov public records Last synced Oct 25, 2026, 12:27 PM EDT

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Showing 985–1008 of 2,080 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Smoking Behavior Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Mobile Cessation Support for Latino Smokers

NCT03586596
View directory record Official record
Conditions
Smoking Cessation
Interventions
The Decídetext program, Standard Care Control
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
21 Years and older
Enrollment
457 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
3
States / cities
Kansas City, Kansas • Hackensack, New Jersey • Rochester, New York
Source: ClinicalTrials.gov public record
Updated Apr 12, 2024 · Synced Oct 25, 2026, 12:27 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Influence of Authorized Smokeless Tobacco Product Modified Risk Claims I: Consumer Product Demand

NCT07102082
View directory record Official record
Conditions
Smoking Behaviors
Interventions
Modified Risk - None, Modified Risk Claim
Behavioral
Lead sponsor
Roswell Park Cancer Institute
Other
Eligibility
21 Years and older
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Oct 25, 2026, 12:27 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Vape-Free Text-Messaging: Pilot Study

NCT05906082
View directory record Official record
Conditions
E-cigarette Use
Interventions
E-cigarette cessation text-messaging intervention, Standard care control using standard national resources
Behavioral
Lead sponsor
Jovan Gwon, PhD, RN, FIAAN
Other
Eligibility
18 Years to 24 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 7, 2025 · Synced Oct 25, 2026, 12:27 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Smoking Treatment of Prisoners

NCT00110630
View directory record Official record
Conditions
Tobacco Use Cessation, Tobacco Use Disorder
Interventions
10-week smoking cessation group therapy combined with NicoDerm CQ
Behavioral
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years to 100 Years · Female only
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 12, 2017 · Synced Oct 25, 2026, 12:27 PM EDT
Completed Not applicable Interventional Results available

Internet-Administered Smoking Cessation Treatment for Overweight and Obese Smokers

NCT01259466
View directory record Official record
Conditions
Smoking Cessation, Overweight, Obesity
Interventions
Nicotine patch
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 28, 2015 · Synced Oct 25, 2026, 12:27 PM EDT
Completed Phase 4 Interventional Results available

Smoking Cessation in Hospitalized Smokers

NCT01289275
View directory record Official record
Conditions
Smoking Cessation
Interventions
Nicotine Patches, Telephone Counseling, Brief Hospital Counseling
Drug · Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
1,270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
6
States / cities
Chula Vista, California • Davis, California • La Jolla, California + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 13, 2020 · Synced Oct 25, 2026, 12:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Tobacco-Related Disease Prevention Among Korean Americans

NCT02584127
View directory record Official record
Conditions
Smoking Cessation
Interventions
high reinforcement cessation program, low reinforcement cessation program
Behavioral
Lead sponsor
University of California, Berkeley
Other
Eligibility
18 Years and older
Enrollment
405 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2015
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated May 13, 2016 · Synced Oct 25, 2026, 12:27 PM EDT
Completed Not applicable Interventional Results available

Smoking Cessation Intervention in Public Housing

NCT01035151
View directory record Official record
Conditions
Cigarette Smoking
Interventions
Experimental, Control
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older · Female only
Enrollment
420 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2018
U.S. locations
2
States / cities
Augusta, Georgia • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Dec 13, 2018 · Synced Oct 25, 2026, 12:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Partnering With Food Bank to Provide Tobacco Treatment to Underserved Smokers

NCT05004662
View directory record Official record
Conditions
Smoking Cessation
Interventions
Smartphone-delivered automated treatment, Nicotine patch, Counseling, Nicotine lozenge
Behavioral · Drug
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older
Enrollment
502 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Oct 25, 2026, 12:27 PM EDT
Completed Phase 3 Interventional Results available

Hutchinson Smoking Prevention Project

NCT00115869
View directory record Official record
Conditions
Smoking Among Youth
Interventions
Social-influences
Behavioral
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
7 Years to 9 Years
Enrollment
8,388 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1984 – 1999
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Nov 29, 2012 · Synced Oct 25, 2026, 12:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparing Nicotine Delivery, Subjective Effects, and Sensory Experiences of Tobacco Users Using Oral Nicotine Products and Electronic Cigarettes [ZYN Study]

NCT05030194
View directory record Official record
Conditions
Tobacco Use, Tobacco Smoking, Cigarette Smoking, Smokeless Tobacco Cessation
Interventions
Electronic Cigarette, Oral Nicotine Pouch
Other
Lead sponsor
Roswell Park Cancer Institute
Other
Eligibility
21 Years to 55 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Oct 26, 2023 · Synced Oct 25, 2026, 12:27 PM EDT
Completed Phase 4 Interventional Results available

A Study To Evaluate The Efficacy And Safety Of Varenicline Compared To Placebo For Smoking Cessation Through Reduction

NCT01370356
View directory record Official record
Conditions
Smoking Cessation
Interventions
Varenicline Tartrate, Placebo
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years and older
Enrollment
1,510 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
14
States / cities
Encino, California • Newport Beach, California • Jacksonville, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated Sep 1, 2014 · Synced Oct 25, 2026, 12:27 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Clinical Response to Biomarker Documentation of Child Secondhand Smoke Exposure

NCT01145729
View directory record Official record
Conditions
Biomarker Feedback, Smoking Cessation, Secondhand Smoke Exposure, Provider Behavior
Interventions
Biomarker Feedback
Behavioral
Lead sponsor
National Institutes of Health (NIH)
NIH
Eligibility
12 Months to 36 Months
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 17, 2010 · Synced Oct 25, 2026, 12:27 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Transcranial Magnetic Brain Stimulation to Reduce Cannabis Use in Heavy Cannabis Users

NCT05401929
View directory record Official record
Conditions
Cannabis
Interventions
iTBS
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2029
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Oct 25, 2026, 12:27 PM EDT
Completed Not applicable Interventional Results available

A Trial of E-cigarettes in Current Cigarette Smokers

NCT02357173
View directory record Official record
Conditions
Smoking, Nicotine Dependence, Nicotine Dependence, Other Tobacco Product
Interventions
electronic cigarette, cigarette group
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 4, 2018 · Synced Oct 25, 2026, 12:27 PM EDT
Completed Phase 3 Interventional

Comparison of Efficacy and Safety of Rimonabant 20mg/Day Versus Placebo in Smoking Cessation

NCT00464256
View directory record Official record
Conditions
Smoking Cessation
Interventions
rimonabant
Drug
Lead sponsor
Sanofi
Industry
Eligibility
18 Years and older
Enrollment
533 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004
U.S. locations
1
States / cities
Bridgewater, New Jersey
Source: ClinicalTrials.gov public record
Updated Dec 10, 2010 · Synced Oct 25, 2026, 12:27 PM EDT
Terminated Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Addressing Post Cessation Weight Gain

NCT02412631
View directory record Official record
Conditions
Obesity, Smoking Cessation
Interventions
lorcaserin, Varenicline, Placebo
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 10, 2021 · Synced Oct 25, 2026, 12:27 PM EDT
Completed Phase 2 Interventional Results available

Do Treatments for Smoking Cessation Affect Alcohol Drinking?

NCT00580645
View directory record Official record
Conditions
Alcohol Drinking
Interventions
varenicline, placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2016
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 7, 2018 · Synced Oct 25, 2026, 12:27 PM EDT
Completed Phase 2 Interventional Results available

Green Tea or Polyphenon E in Preventing Lung Cancer in Former Smokers With Chronic Obstructive Pulmonary Disease

NCT00363805
View directory record Official record
Conditions
Lung Cancer Prevention
Interventions
green tea, Polyphenon E, placebo
Dietary Supplement · Drug · Other
Lead sponsor
Sherry Chow
Other
Eligibility
40 Years to 80 Years
Enrollment
178 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2004
U.S. locations
3
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Nov 28, 2013 · Synced Oct 25, 2026, 12:27 PM EDT
Completed No phase listed Observational

Airway Epithelium Gene Expression: AEGIS IDE

NCT00746759
View directory record Official record
Conditions
Lung Cancer
Interventions
Biomarker (not used as an intervention)
Device
Lead sponsor
Allegro Diagnostics, Corp.
Industry
Eligibility
21 Years and older
Enrollment
1,331 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
21
States / cities
Birmingham, Alabama • Phoenix, Arizona • Sacramento, California + 17 more
Source: ClinicalTrials.gov public record
Updated Jun 4, 2015 · Synced Oct 25, 2026, 12:27 PM EDT
Completed Phase 4 Interventional

The Whole Day First Grade Program

NCT00257088
View directory record Official record
Conditions
Prevention of Drug Abuse and Dependency, Alcohol Abuse and Dependency, High Risk Sex Behavior, Smoking Tobacco, School Failure
Interventions
whole day first grade program
Behavioral
Lead sponsor
American Institutes for Research
Other
Eligibility
Not listed
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2003
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 14, 2008 · Synced Oct 25, 2026, 12:27 PM EDT
Completed Phase 4 Interventional Results available

Identifying Optimal Smoking Cessation Intervention Components (Cessation)

NCT01116986
View directory record Official record
Conditions
Smoking, Smoking Cessation, Nicotine Dependence
Interventions
Counseling before quit attempt, Minimal In-person counseling during quit attempt, Intensive in-person counseling during the quit attempt, Minimal phone counseling during the quit attempt, Intensive phone counseling during the quit attempt, Long Term Nicotine Patch+ Nicotine Gum During Quit Attempt, Short Term Nicotine Patch + Nicotine Gum during the quit attempt, Pre-Quit Nicotine Gum, Pre-Quit Nicotine Patch, Pre-Quit Nicotine Patch + Pre-Quit Nicotine Gum
Behavioral · Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 99 Years
Enrollment
637 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 11, 2015 · Synced Oct 25, 2026, 12:27 PM EDT
Completed Not applicable Interventional Results available

Menominee Stop Tobacco Abuse Renew Tradition Study

NCT01083654
View directory record Official record
Conditions
Smoking
Interventions
Standard Treatment Counseling, Culturally-Tailored Treatment
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Keshena, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 17, 2016 · Synced Oct 25, 2026, 12:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Optimizing Risk Messages for Waterpipe Tobacco Cessation in Young Adults

NCT03595280
View directory record Official record
Conditions
Hookah Smoking
Interventions
Hookah tobacco risk messages
Behavioral
Lead sponsor
Georgetown University
Other
Eligibility
18 Years to 30 Years
Enrollment
349 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 20, 2021 · Synced Oct 25, 2026, 12:27 PM EDT