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ClinicalTrials.gov public records Last synced Oct 26, 2026, 2:09 PM EDT

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Showing 1057–1080 of 2,080 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Smoking Behavior Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Smoker-to-Smoker (S2S) Peer Marketing and Messaging to Disseminate Tobacco Interventions

NCT03224520
View directory record Official record
Conditions
Smoking Cessation
Interventions
Recommender CTHC, Standard CTHC, Peer Recruitment, Standard Online Recruitment
Behavioral · Other
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
1,487 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 26, 2021 · Synced Oct 26, 2026, 2:09 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Health Communications for Adults Smoking Nondaily

NCT07296848
View directory record Official record
Conditions
Smoking Cessation
Interventions
Targeted Smoking Messages
Behavioral
Lead sponsor
Bethany Shorey Fennell, PhD
Other
Eligibility
18 Years and older
Enrollment
320 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Oct 26, 2026, 2:09 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Neurobiology of Nicotine and Non-nicotine Components of Tobacco Addiction

NCT01056926
View directory record Official record
Conditions
Smoking
Interventions
Quit smoking, Nicotine patch, Placebo Patch
Behavioral · Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 55 Years
Enrollment
147 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 31, 2017 · Synced Oct 26, 2026, 2:09 PM EDT
Completed No phase listed Observational

Meriter Mindfulness Training for Smokers Program and Study

NCT02143752
View directory record Official record
Conditions
Smoking
Interventions
Mindfulness, Quit Line
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 18, 2023 · Synced Oct 26, 2026, 2:09 PM EDT
Withdrawn Phase 4 Interventional

Treating Schizophrenic Smokers: Effects on Craving, Cues and Withdrawal

NCT00781755
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
varenicline, Adaptation of Motivational Interviewing
Drug · Behavioral
Lead sponsor
VA Boston Healthcare System
Federal
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
Brockton, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 4, 2015 · Synced Oct 26, 2026, 2:09 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Nicotine and Brain Imaging Research Study

NCT01227343
View directory record Official record
Conditions
Nicotine
Interventions
Not listed
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 50 Years
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 4, 2021 · Synced Oct 26, 2026, 2:09 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Equitable Smoking Relapse Prevention

NCT05625685
View directory record Official record
Conditions
Tobacco Use Disorder, Tobacco Dependence
Interventions
Quitbuddy, Control, SDoH Augmentation, SDoH Control
Other
Lead sponsor
Bryan W. Heckman
Other
Eligibility
21 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 8, 2024 · Synced Oct 26, 2026, 2:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Computer-Facilitated 5A's for Smoking Cessation in Primary Care

NCT02046408
View directory record Official record
Conditions
Nicotine Addiction, Smoking Cessation
Interventions
Computer Tablet
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 100 Years
Enrollment
961 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
2
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 7, 2017 · Synced Oct 26, 2026, 2:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Yoga and Cardiovascular Exercise on Smoking Motivation

NCT01423578
View directory record Official record
Conditions
Tobacco Dependence
Interventions
Hatha Yoga (HY), Cardiovascular Exercise (CE), Smoking Cessation Counseling
Behavioral
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years to 55 Years
Enrollment
79 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2017
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jun 26, 2017 · Synced Oct 26, 2026, 2:09 PM EDT
Terminated Not applicable Interventional

Comprehensive Care Program SBRT

NCT03267368
View directory record Official record
Conditions
Lung Cancer, Smoking, Copd
Interventions
Comprehensive Care Program
Behavioral
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
2
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 13, 2020 · Synced Oct 26, 2026, 2:09 PM EDT
Completed Phase 2 Interventional

Pulmonary and Cardiac Effects of E-Cigarette Use in Pulmonary Patients Who Smoke Cigarettes

NCT05610514
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease, Chronic Bronchitis, Emphysema, Asthma-COPD Overlap Syndrome
Interventions
E-Cigarette, Financial Incentives
Other · Behavioral
Lead sponsor
University of Vermont
Other
Eligibility
40 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Feb 8, 2024 · Synced Oct 26, 2026, 2:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Nicotine Uptake, Measures of Abuse Liability, and Puffing Topography With Use of RELX ENDS Products by ENDS Consumers

NCT04620616
View directory record Official record
Conditions
Electronic Cigarette Use
Interventions
RELX ENDS Tobacco Flavor, RELX ENDS Menthol Flavor, Subject Usual Brand ENDS
Other
Lead sponsor
Cheerain HK Limited
Industry
Eligibility
22 Years to 59 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
2
States / cities
Cypress, California • Overland Park, Kansas
Source: ClinicalTrials.gov public record
Updated Jan 19, 2021 · Synced Oct 26, 2026, 2:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Patient Experience Recommender System for Persuasive Communication Tailoring

NCT02200432
View directory record Official record
Conditions
Smoking Cessation
Interventions
PERSPeCT Recommender System
Other
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
972 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 9, 2015 · Synced Oct 26, 2026, 2:09 PM EDT
Recruiting Phase 2Phase 3 Interventional Accepts healthy volunteers

Empowering Cessation ACS South Region

NCT06820034
View directory record Official record
Conditions
Smoking Cessation
Interventions
Empowering Cessation for the ACS South
Other
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 100 Years
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Oct 26, 2026, 2:09 PM EDT
Completed Not applicable Interventional Results available

Integrating Tobacco Treatment Into Cancer Care: A Randomized Controlled Comparative Effectiveness Trial

NCT01871506
View directory record Official record
Conditions
Smoking Cessation
Interventions
Standard Care (SC), Intensive Counseling (IC)
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
303 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
3
States / cities
Boston, Massachusetts • New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 28, 2019 · Synced Oct 26, 2026, 2:09 PM EDT
Not yet recruiting Phase 1 Interventional

Development of a MHBC Intervention for Weight Loss and Smoking Cessation for Pre-Bariatric Surgery Patients

NCT07224087
View directory record Official record
Conditions
Obesity, Smoking Cessation, Bariatric Surgery Patients
Interventions
Naltrexone Hydrochloride, Bupropion HCl Extended Release, Cognitive-Behavioral Therapy
Drug · Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 26, 2026, 2:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

CONNECT: Smoking Cessation and Lung Cancer Screening

NCT04149249
View directory record Official record
Conditions
Smoking Cessation
Interventions
Computer-Assisted Intervention Video Doctor, Computer-Assisted Intervention no Video Doctor
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
55 Years to 80 Years
Enrollment
99 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
2
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 15, 2023 · Synced Oct 26, 2026, 2:09 PM EDT
Not yet recruiting Not applicable Interventional

Cardiovascular Impacts of E-cigarettes Among Older Adults

NCT07880704
View directory record Official record
Conditions
Hypertension, Tobacco Cigarette Smoking, Electronic Cigarettes, Cardiovascular
Interventions
Nicotine E-cigarette, Tobacco Cigarette
Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
50 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 19, 2026 · Synced Oct 26, 2026, 2:09 PM EDT
Withdrawn Not applicable Interventional

Cognitive and Emotional Skills to Aid Smoking Cessation

NCT03148652
View directory record Official record
Conditions
Cigarette Smoking
Interventions
Enhanced Intervention Condition
Other
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 10, 2019 · Synced Oct 26, 2026, 2:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

E-Cigarettes and Financial Incentives to Promote Tobacco Harm Reduction Among Adults Accessing Shelter Services

NCT03743532
View directory record Official record
Conditions
Cigarette Smoking
Interventions
E-cigarette Switching, Financial Incentives
Behavioral
Lead sponsor
University of Oklahoma
Other
Eligibility
21 Years to 100 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Feb 21, 2025 · Synced Oct 26, 2026, 2:09 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Understanding the Impact of Cartridge-Based Electronic Cigarettes and Generated Aerosols on Cardiopulmonary Health

NCT05199480
View directory record Official record
Conditions
E-Cig Use
Interventions
Tobacco flavored liquid type 1, Tobacco flavored liquid type 2
Drug
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
21 Years and older
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 1, 2025 · Synced Oct 26, 2026, 2:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study of a Smartphone-Based Switch Program

NCT06544772
View directory record Official record
Conditions
Smoking Cessation
Interventions
Pivot cigarette smoking cessation program
Device
Lead sponsor
Pivot Health Technologies Inc.
Industry
Eligibility
21 Years to 65 Years
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
San Carlos, California
Source: ClinicalTrials.gov public record
Updated Oct 2, 2025 · Synced Oct 26, 2026, 2:09 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Translational Research Center in Lung Cancer Disparities (TRACER) Project 2

NCT05490251
View directory record Official record
Conditions
Smoking, Smoking Behaviors, Smoking Cessation, Stress Reaction
Interventions
Not listed
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 75 Years · Male only
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
2
States / cities
Los Angeles, California • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Oct 26, 2026, 2:09 PM EDT
Not yet recruiting Not applicable Interventional

Quit With Sense: Using Mindful Smoking and Wearable Device for Smoking Cessation

NCT07789496
View directory record Official record
Conditions
Smoking Cessation, Cigarette Smoking, Tobacco Use, Nicotine Dependence
Interventions
Mindful Smoking and Sensor-Band Intervention, Smoking Cessation Information
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 26, 2026, 2:09 PM EDT