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ClinicalTrials.gov public records Last synced Oct 27, 2026, 11:25 AM EDT

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Showing 1177–1200 of 2,082 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Smoking Behavior Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Integrating Clinical Practice Guidelines for Smoking Cessation Into Mental Health Care for Veterans With Posttraumatic Stress Disorder

NCT00118534
View directory record Official record
Conditions
Mental Health, Stress Disorders, Post-Traumatic, Substance-Related Disorders, Tobacco Use Disorder
Interventions
Integrated Care for Smoking Cessation in PTSD patients, Standard of Care
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 80 Years
Enrollment
943 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2009
U.S. locations
11
States / cities
Tuscaloosa, Alabama • San Diego, California • Washington D.C., District of Columbia + 8 more
Source: ClinicalTrials.gov public record
Updated May 5, 2014 · Synced Oct 27, 2026, 11:25 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Lombardi Comprehensive Cancer Center/Legacy Pilot Study to Reduce Adverse Smoking Outcomes in the Context of Lung Cancer Screening

NCT02267096
View directory record Official record
Conditions
Smoking, Lung Cancer
Interventions
Telephone Counseling, Minimal Treatment
Behavioral
Lead sponsor
Georgetown University
Other
Eligibility
55 Years to 80 Years
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
3
States / cities
Washington D.C., District of Columbia • Burlington, Massachusetts • Hackensack, New Jersey
Source: ClinicalTrials.gov public record
Updated Oct 19, 2016 · Synced Oct 27, 2026, 11:25 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Testing the Efficacy of A Scalable, Telephone-Delivered, Guided Imagery Tobacco Cessation Intervention

NCT05277831
View directory record Official record
Conditions
Smoking Cessation, Smoking, Smoking Reduction, Smoking, Cigarette, Smoking (Tobacco) Addiction, Smoking Habit
Interventions
Guided Imagery Intervention, Standard Behavioral Control
Other
Lead sponsor
University of Arizona
Other
Eligibility
18 Years and older
Enrollment
1,209 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Oct 16, 2026 · Synced Oct 27, 2026, 11:25 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Culturally Targeted & Individually Tailored Smoking Cessation Study: LGBT Smokers

NCT01633567
View directory record Official record
Conditions
Cigarette Smoking
Interventions
Culturally Targeted Cessation Program, Non-Targeted Cessation Program
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years to 65 Years
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 4, 2017 · Synced Oct 27, 2026, 11:25 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

The Efficacy of Conventional Screening Versus mHealth Screening in Early Detection of Oral Potentially Malignant Disorders and Oral Cancer Amongst the Rural Population of Varanasi: A Prospective and Blinded Study

NCT06535867
View directory record Official record
Conditions
Smoking, Smoking, Cigarette, Smoking, Tobacco, Betel Chewer's Mucosa, Tobacco Use, Tobacco Smoking, Alcohol Drinking, Smokeless Tobacco Hyperkeratosis
Interventions
mHealth
Diagnostic Test
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
5,122 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2031
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 27, 2026, 11:25 AM EDT
Completed Not applicable Interventional Results available

Improving Adherence to Web-Based Cessation Programs: A Social Network Approach

NCT01544153
View directory record Official record
Conditions
Smoking Cessation
Interventions
WEB, Social Network, Nicotine Replacement Therapy (NRT)
Behavioral
Lead sponsor
Truth Initiative
Other
Eligibility
18 Years and older
Enrollment
5,292 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Oct 21, 2026 · Synced Oct 27, 2026, 11:25 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Controlled Study of the Ability of a Smokefree Tobacco Product to Increase the Quit Rate Among Cigarette Smokers

NCT00843622
View directory record Official record
Conditions
Cigarette Smoking
Interventions
Low-nitrosamine smokefree tobacco product for oral use, Non-tobacco, non-nicotine placebo product
Drug · Other
Lead sponsor
Swedish Match AB
Industry
Eligibility
25 Years to 65 Years
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
4
States / cities
Daytona Beach, Florida • Evansville, Indiana • Portland, Oregon + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 17, 2014 · Synced Oct 27, 2026, 11:25 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effectiveness of the American Lung Association Reactive Anti-Smoking Telephone Help Line in Illinois

NCT00749151
View directory record Official record
Conditions
Smoking
Interventions
telephone counseling
Behavioral
Lead sponsor
Southern Illinois University
Other
Eligibility
18 Years and older
Enrollment
990 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2007
U.S. locations
1
States / cities
Springfield, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 18, 2010 · Synced Oct 27, 2026, 11:25 AM EDT
Completed Not applicable Interventional Results available

Pain and Smoking Study

NCT02971137
View directory record Official record
Conditions
Smoking, Pain, Smoking Cessation
Interventions
Smoking Cessation plus CBI, Smoking Cessation Standard
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
371 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
2
States / cities
West Haven, Connecticut • Leeds, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 28, 2023 · Synced Oct 27, 2026, 11:25 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Peer-delivered and Technology-Assisted Integrated Illness Management and Recovery

NCT04481737
View directory record Official record
Conditions
Schizophrenia, Bipolar Disorder, Major Depressive Disorder, Recurrent, Obesity, Cardiovascular Diseases, Diabetes, Smoking, Blood Pressure Disorders, Cholesterol, Elevated
Interventions
Peer-delivered and Technology Support Integrated Illness Management and Recovery, Peer support
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 24, 2024 · Synced Oct 27, 2026, 11:25 AM EDT
Completed Not applicable Interventional

Technology and Telephone-Based Smoking Cessation

NCT03492645
View directory record Official record
Conditions
Smoking Cessation
Interventions
Telephone-and technology-facilitated treatment protocol, Office-based treatment protocol
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 69 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 30, 2019 · Synced Oct 27, 2026, 11:25 AM EDT
Terminated Phase 2 Interventional Results available

Effects of ABT-089 on Smoking Abstinence Symptoms and Reward

NCT01756053
View directory record Official record
Conditions
Nicotine Addiction
Interventions
ABT-089, Placebo
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 65 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 29, 2014 · Synced Oct 27, 2026, 11:25 AM EDT
Completed Not applicable Interventional

Technological Innovations in Behavioral Treatments for Cigarette Smoking

NCT00926939
View directory record Official record
Conditions
Cigarette Smoking
Interventions
Reinforcement for the abstinence of smoking, Reinforcement for submission of videos with CO sample
Behavioral
Lead sponsor
National Development and Research Institutes, Inc.
Other
Eligibility
18 Years and older
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 14, 2015 · Synced Oct 27, 2026, 11:25 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Project Quit: Positive vs. Negative Offers of an Online Stop Smoking Program

NCT01923467
View directory record Official record
Conditions
Smoking Cessation
Interventions
Project Quit stop smoking program, Nicotine patches 21 mg
Behavioral · Drug
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
767 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 15, 2015 · Synced Oct 27, 2026, 11:25 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Nicotine Receptor Density & Response to Nicotine Patch: Pt 2 Extended Treatment

NCT02676375
View directory record Official record
Conditions
Smoking Cessation, Schizophrenia
Interventions
Combination Bupropion + NRTs, Extended Treatment, Home Visits & Calls, Monotherapy
Drug · Other
Lead sponsor
Brentwood Biomedical Research Institute
Other
Eligibility
21 Years and older
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 30, 2019 · Synced Oct 27, 2026, 11:25 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Substance Treatment and HIV Testing and Referral System

NCT01488630
View directory record Official record
Conditions
Substance Abuse
Interventions
STaRS
Other
Lead sponsor
Polaris Health Directions
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Camden, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 18, 2018 · Synced Oct 27, 2026, 11:25 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cardiovascular Assessment of the Effects of Tobacco and Nicotine Delivery Products

NCT01964807
View directory record Official record
Conditions
Adverse Effect of Other Agents Primarily Affecting the Cardiovascular System, Initial Encounter
Interventions
Cigarette, NIDA test type with 16.6 mg nicotine, Cigarette, NIDA test type with <0.45 mg nicotine, Electronic cigarette with 18 mg/ml nicotine, Electronic Cigarette with no nicotine, Moist snuff, Sham Smoking, Secondhand cigarette smoke (SHS), Conditioned, filtered air, Sham Moist Snuff
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 50 Years
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2021
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Dec 27, 2021 · Synced Oct 27, 2026, 11:25 AM EDT
Completed Not applicable Interventional

Quitline Use in Surgical Patients

NCT00656500
View directory record Official record
Conditions
Tobacco Dependence
Interventions
Standard brief advice, Quitline intervention
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 3, 2012 · Synced Oct 27, 2026, 11:25 AM EDT
Terminated Phase 2Phase 3 Interventional

Mindfulness Training Plus Oxytocin Effects on Smoking Behavior

NCT03819231
View directory record Official record
Conditions
Smoking, Smoking Cessation
Interventions
Oxytocin, Mindfulness, Saline Solution, Sham mindfulness
Drug · Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 40 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 14, 2024 · Synced Oct 27, 2026, 11:25 AM EDT
Completed Not applicable Interventional Results available

Evaluating E-Cigarette Nicotine Form, Concentration, and Flavors Among Youth

NCT05458895
View directory record Official record
Conditions
E-cigarette Use
Interventions
ECIG lab session 1, ECIG lab session 2, ECIG lab session 3, ECIG lab session 4, ECIG lab session 5, ECIG lab session 6, ECIG lab session 7, ECIG lab session 8
Other
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
21 Years to 25 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 22, 2024 · Synced Oct 27, 2026, 11:25 AM EDT
Recruiting Not applicable Interventional

Family-Based Financial Incentives Intervention for Smoking Cessation

NCT06556433
View directory record Official record
Conditions
Smoking Cessation
Interventions
Financial Incentive Rewards
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
1,312 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Anchorage, Alaska
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Oct 27, 2026, 11:25 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

CSD170301: An Unblinded, Parallel, Randomized Study to Assess Nicotine Uptake in Smokers From Four Different Electronic Cigarettes

NCT03105804
View directory record Official record
Conditions
Smoking
Interventions
FT21039, FT21041, FT21044, FT21042
Other
Lead sponsor
RAI Services Company
Industry
Eligibility
21 Years to 60 Years
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
2
States / cities
Neptune City, New Jersey • High Point, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 10, 2018 · Synced Oct 27, 2026, 11:25 AM EDT
Not listed Not applicable Interventional

Intervening to Promote Tobacco Cessation Following Psychiatric Hospitalization

NCT05672914
View directory record Official record
Conditions
Smoking Cessation
Interventions
Tablet-based sustained care
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated May 8, 2024 · Synced Oct 27, 2026, 11:25 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Smoking Cessation for Young Adults Who Binge Drink - 1

NCT00218452
View directory record Official record
Conditions
Adherence, Tobacco Use Cessation, Alcohol & Drug Use, Nicotine Transdermal System
Interventions
Lifestyle counseling
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 25 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2008
U.S. locations
3
States / cities
Jacksonville, Florida • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 7, 2015 · Synced Oct 27, 2026, 11:25 AM EDT