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ClinicalTrials.gov public records Last synced Oct 28, 2026, 6:39 PM EDT

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Showing 1321–1344 of 2,082 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Smoking Behavior Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Tobacco Cessation Intervention

NCT03657511
View directory record Official record
Conditions
Smoking Tobacco
Interventions
Educational Interventions to Promote Tobacco Cessation
Behavioral
Lead sponsor
Barbara Ann Karmanos Cancer Institute
Other
Eligibility
21 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated May 6, 2022 · Synced Oct 28, 2026, 6:39 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Natural History of Attempts to Stop Smoking

NCT00995644
View directory record Official record
Conditions
Tobacco Use Cessation
Interventions
Not listed
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
238 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Oct 31, 2016 · Synced Oct 28, 2026, 6:39 PM EDT
Completed Not applicable Interventional Results available

Racial Differences in Circadian and Sleep Mechanisms for Nicotine Dependence, Craving, and Withdrawal

NCT03968900
View directory record Official record
Conditions
Smoking, Sleep Disturbance, Nicotine Dependence
Interventions
Sleep restriction condition, Sleep extension condition
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Oct 28, 2026, 6:39 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Facilitating Implementation of the PHS Smoking Cessation Guidelines - RESET

NCT00057070
View directory record Official record
Conditions
Smoking Cessation, Randomized Controlled Trial
Interventions
Smoking cessation information, collection, and dissemination
Procedure
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
19 Years and older
Enrollment
1,900 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2003
U.S. locations
2
States / cities
Minneapolis, Minnesota • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 7, 2015 · Synced Oct 28, 2026, 6:39 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Breathe 2 Project 3: Comprehensive Chronic Care

NCT05382221
View directory record Official record
Conditions
Smoking Cessation, Smoking Abstinence
Interventions
Comprehensive Chronic Care, Standard Care
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
979 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
2
States / cities
Madison, Wisconsin • Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 18, 2025 · Synced Oct 28, 2026, 6:39 PM EDT
Completed Not applicable Interventional

ROSCAP: Reduction of Smoking in Cardiac Patients Study

NCT00301626
View directory record Official record
Conditions
Nicotine Dependence, Tobacco Dependence, Cardiac Disease
Interventions
smoking reduction intervention (including NRT)
Behavioral
Lead sponsor
National Institutes of Health (NIH)
NIH
Eligibility
18 Years to 80 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2005
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 24, 2008 · Synced Oct 28, 2026, 6:39 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of e-Cigarettes on Perceptions and Behavior

NCT03742817
View directory record Official record
Conditions
Electronic Cigarettes
Interventions
e-Cigarette
Other
Lead sponsor
University of Southern California
Other
Eligibility
21 Years and older
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 11, 2023 · Synced Oct 28, 2026, 6:39 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Smoking Cessation Tailored to Rural Young Adult African American Men:

NCT03808714
View directory record Official record
Conditions
Smoking Cessation
Interventions
TOUCHDOWN, Control Group
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 30 Years · Male only
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 10, 2021 · Synced Oct 28, 2026, 6:39 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

CONNECT: Smoking Cessation and Lung Cancer Screening

NCT04149249
View directory record Official record
Conditions
Smoking Cessation
Interventions
Computer-Assisted Intervention Video Doctor, Computer-Assisted Intervention no Video Doctor
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
55 Years to 80 Years
Enrollment
99 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
2
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 15, 2023 · Synced Oct 28, 2026, 6:39 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Applying Novel Technologies and Methods to Self-Regulation: Behavior Change Tools for Smoking and Binge Eating

NCT03687658
View directory record Official record
Conditions
Smoking, Binge Eating, Behavior
Interventions
Laddr
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 50 Years
Enrollment
91 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Sep 28, 2023 · Synced Oct 28, 2026, 6:39 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Disease Management for Smoking Cessation

NCT00440115
View directory record Official record
Conditions
Smoking Cessation
Interventions
High intensity disease management, Low intensity disease management, Comparison group, Bupropion
Behavioral · Drug
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older
Enrollment
750 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jun 7, 2017 · Synced Oct 28, 2026, 6:39 PM EDT
Completed Not applicable Interventional Results available

Message Testing in Older Adult Smokers

NCT05471349
View directory record Official record
Conditions
Smoking, Smoking Cessation
Interventions
Flyer and video
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
50 Years to 80 Years
Enrollment
820 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jan 31, 2024 · Synced Oct 28, 2026, 6:39 PM EDT
Recruiting Not applicable Interventional

Identify the Optimal TMS Pulse Protocol to Modulate Reward Activity

NCT06695884
View directory record Official record
Conditions
Nicotine Use Disorder
Interventions
Transcranial Magnetic Stimulation
Device
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 55 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Nov 18, 2025 · Synced Oct 28, 2026, 6:39 PM EDT
Completed Not applicable Interventional

Construal Level as a Novel Pathway for Affect Regulation and Cancer Control

NCT04620915
View directory record Official record
Conditions
Smoking Cessation, Smoking Reduction, Cancer
Interventions
High-level construal, Down-regulation of craving for cigarettes, Up-regulation of goal energization
Behavioral
Lead sponsor
University of Oregon
Other
Eligibility
25 Years to 55 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
2
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Oct 28, 2026, 6:39 PM EDT
Completed Not applicable Interventional Results available

Effect of Smoking Exposure on Smoking Relapse Following Brief Abstinence - 2

NCT00136838
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
Neutral or active cigarette cues
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
21 Years to 45 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2006
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 18, 2018 · Synced Oct 28, 2026, 6:39 PM EDT
Recruiting Not applicable Interventional

Feasibility and Acceptability Trial to Reduce Tobacco and Cannabis Use During Pregnancy and Postpartum

NCT07489443
View directory record Official record
Conditions
Perinatal, Cannabis Use, Tobacco Use, Smoking Cessation
Interventions
Perinatal smoking cessation treatment and maintenance sessions
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older · Female only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Oct 28, 2026, 6:39 PM EDT
Completed No phase listed Observational

Vape Use Among Younger & Older Smokers

NCT07214168
View directory record Official record
Conditions
Smoking Cigarette, Smoking Behaviors, Vaping, Vaping Behaviors
Interventions
Not listed
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
21 Years to 65 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 28, 2026, 6:39 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Testing an MBI for Smoking Cessation and Alcohol Use Among Cancer Survivors

NCT07447635
View directory record Official record
Conditions
Smoking Cessation, Alcohol Use
Interventions
Mindfulness-Based Relapse Prevention for Smoking and Alcohol (MBRP-SA), Quitline Support
Behavioral
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Oct 28, 2026, 6:39 PM EDT
Completed Phase 2 Interventional Results available

Effect of Galantamine on Smoking Abstinence

NCT01548638
View directory record Official record
Conditions
Nicotine Addiction
Interventions
Galantamine ER
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 60 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 26, 2017 · Synced Oct 28, 2026, 6:39 PM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers

School Nurse-Delivered Smoking Cessation Intervention

NCT00682474
View directory record Official record
Conditions
Cigarette Smoking, Nicotine Dependence
Interventions
Counseling Intervention, Information Intervention
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
13 Years to 18 Years
Enrollment
1,058 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2010
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 19, 2011 · Synced Oct 28, 2026, 6:39 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Measuring Smoking Behaviors While Using Varenicline

NCT00948155
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Varenicline
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
21 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 16, 2014 · Synced Oct 28, 2026, 6:39 PM EDT
Completed Not applicable Interventional Results available

Learn to Quit-HIV Pilot Study

NCT04609514
View directory record Official record
Conditions
HIV/AIDS, Smoking Cessation, Tobacco Use Disorder
Interventions
Learn to Quit-HIV, QuitGuide, Nicotine patch, Smartphone coaching
Device · Behavioral · Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 19, 2023 · Synced Oct 28, 2026, 6:39 PM EDT
Recruiting Phase 1Phase 2 Interventional Accepts healthy volunteers

Hyperpolarized Xenon-129 MR Imaging of the Lung

NCT04662658
View directory record Official record
Conditions
E-Cig Use
Interventions
Hyperpolarized Xenon -129 MRI
Drug
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 10, 2020 · Synced Oct 28, 2026, 6:39 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

MassCONECT (Massachusetts Community Networks to Eliminate Cancer Disparities Through Education) 4 Kids: Promoting Smoke-free Homes

NCT01537874
View directory record Official record
Conditions
Tobacco Smoking Behavior
Interventions
Motivational Interview, Usual best practices
Behavioral
Lead sponsor
Harvard School of Public Health (HSPH)
Other
Eligibility
17 Years and older
Enrollment
138 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
3
States / cities
Boston, Massachusetts • Lawrence, Massachusetts • Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 20, 2014 · Synced Oct 28, 2026, 6:39 PM EDT