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ClinicalTrials.gov public records Last synced Oct 29, 2026, 2:28 AM EDT

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Showing 1345–1368 of 2,082 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Smoking Behavior Clear all
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Treatment of Smoking Lapses and Relapses

NCT01807871
View directory record Official record
Conditions
Smoking Cessation
Interventions
nicotine patch, experimental use, nicotine patch, labeled use
Drug
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
701 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Oct 13, 2017 · Synced Oct 29, 2026, 2:28 AM EDT
Completed Not applicable Interventional Results available

Testing an Organizational Change Model to Address Smoking in Mental Healthcare

NCT02849652
View directory record Official record
Conditions
Nicotine Dependence
Interventions
ATTOC Intervention, UC Intervention
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 99 Years
Enrollment
832 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 21, 2023 · Synced Oct 29, 2026, 2:28 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Developing and Testing Health Warning Labels on the ENDS Device

NCT04907136
View directory record Official record
Conditions
Electronic Cigarette Use
Interventions
Preferred ENDS, Preferred ENDS with HWL
Other
Lead sponsor
Florida International University
Other
Eligibility
21 Years to 35 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jun 5, 2026 · Synced Oct 29, 2026, 2:28 AM EDT
Completed Phase 1Phase 2 Interventional

The Role of Nicotine and Non-Nicotine Alkaloids in E-Cigarette Use and Dependence

NCT02590393
View directory record Official record
Conditions
Nicotine Dependence
Interventions
E-cigarettes
Combination Product
Lead sponsor
Duke University
Other
Eligibility
21 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 21, 2024 · Synced Oct 29, 2026, 2:28 AM EDT
Recruiting Not applicable Interventional

Scalable TELeheaLth Cancer CARe: The STELLAR Program to Treat Cancer Risk Behaviors

NCT05687604
View directory record Official record
Conditions
Obesity, Smoking Cessation, Physical Inactivity
Interventions
multiple behavior change therapy
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
1,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 8, 2026 · Synced Oct 29, 2026, 2:28 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Comparison of Smoking and Vaping in Families

NCT02500238
View directory record Official record
Conditions
Smoking
Interventions
Saliva sample, Urine Sample, Toe nail clippings, Breath carbon monoxide test
Other
Lead sponsor
University of Florida
Other
Eligibility
6 Years to 17 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
2
States / cities
Gainesville, Florida • Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Dec 28, 2018 · Synced Oct 29, 2026, 2:28 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effect of Electronic Cigarette Liquid Characteristics in Smokers.

NCT03861078
View directory record Official record
Conditions
Electronic Cigarettes
Interventions
Own Brand Cigarette, ECIG 15 mg nicotine, sweetened, ECIG 15 mg nicotine, unsweet, ECIG 0 mg nicotine, sweetened, ECIG 0 mg nicotine, unsweet
Other
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
21 Years to 55 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 23, 2022 · Synced Oct 29, 2026, 2:28 AM EDT
Completed Phase 1 Interventional Results available

Improving Functional Outcomes of Veterans With PTSD and Tobacco Dependence

NCT02576899
View directory record Official record
Conditions
Tobacco, Posttraumatic Stress Disorder
Interventions
Acceptance and Commitment Therapy for PTSD and Tobacco Use, Freedom From Smoking
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Bedford, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 10, 2020 · Synced Oct 29, 2026, 2:28 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Smoking Cessation Via Text Messaging: Feasibility Testing of Stop My Smoking USA

NCT01516632
View directory record Official record
Conditions
Smoking Cessation
Interventions
SMS USA
Behavioral
Lead sponsor
Center for Innovative Public Health Research
Other
Eligibility
18 Years to 25 Years
Enrollment
164 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Santa Ana, California
Source: ClinicalTrials.gov public record
Updated Jun 6, 2016 · Synced Oct 29, 2026, 2:28 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Translating Extinction Research to Improve Pharmacotherapy for Tobacco Dependence

NCT02202499
View directory record Official record
Conditions
Smoking Cessation, Tobacco Dependence
Interventions
Varenicline, Counseling and Support Materials, Laboratory Assessments
Drug · Other
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older
Enrollment
86 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Nov 27, 2020 · Synced Oct 29, 2026, 2:28 AM EDT
Completed No phase listed Observational

Meriter Mindfulness Training for Smokers Program and Study

NCT02143752
View directory record Official record
Conditions
Smoking
Interventions
Mindfulness, Quit Line
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 18, 2023 · Synced Oct 29, 2026, 2:28 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Flavors and E-cigarette Effects in Adolescent Smokers- STUDY 1

NCT02179034
View directory record Official record
Conditions
Nicotine Dependence, Other Tobacco Product
Interventions
Nicotine, Low Dose Menthol, High Dose Menthol
Drug · Other
Lead sponsor
Yale University
Other
Eligibility
18 Years to 20 Years
Enrollment
59 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 4, 2020 · Synced Oct 29, 2026, 2:28 AM EDT
Active, not recruiting Not applicable Interventional

A Novel Dialectical Behavior Therapy Brief Group Intervention for Cigarette Smoking by Patients With Cancer: An Open Clinical Trial

NCT07119489
View directory record Official record
Conditions
Smoking Behavior
Interventions
Dialectical Behavior Therapy -Skill Training brief intervention
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
2
States / cities
Charlotte, North Carolina • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 23, 2026 · Synced Oct 29, 2026, 2:28 AM EDT
Completed Phase 1 Interventional

Multiple Dose, Dose Escalation Study of Varenicline Controlled Release Formulation in Adult Smokers

NCT00527150
View directory record Official record
Conditions
Smoking Cessation
Interventions
Varenicline Tartrate
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 55 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
2
States / cities
East Grand Forks, Minnesota • Fargo, North Dakota
Source: ClinicalTrials.gov public record
Updated Jan 11, 2010 · Synced Oct 29, 2026, 2:28 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Comprehensive Practice-Friendly Model for Promoting Healthy Behaviors

NCT00292968
View directory record Official record
Conditions
Unhealthy Diet, Exercise, Smoking, and Alcohol Use
Interventions
Computer based care, Telephone counseling, Group visits, Usual care
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
5,670 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
1
States / cities
Newport News, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 20, 2012 · Synced Oct 29, 2026, 2:28 AM EDT
Not listed Not applicable Interventional

Harm Reduction for Tobacco Smoking With Support of Tobacco-Replacing Electronic Nicotine Delivery Systems

NCT03962660
View directory record Official record
Conditions
Smoking, Tobacco
Interventions
HaRTS-TRENDS, Standard Care (SC)
Other
Lead sponsor
University of Washington
Other
Eligibility
21 Years to 65 Years
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 24, 2019 · Synced Oct 29, 2026, 2:28 AM EDT
Completed Not applicable Interventional Results available

Acceptance and Commitment Therapy for Tobacco Cessation Among Psychiatric Partial Hospital Patients

NCT03911960
View directory record Official record
Conditions
Tobacco Smoking, Psychiatric Disorder, Psychiatric Hospitalization
Interventions
Acceptance and Commitment Therapy, Enhanced Usual Care
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 25, 2020 · Synced Oct 29, 2026, 2:28 AM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Varenicline and Bupropion for Smoking Cessation

NCT00935818
View directory record Official record
Conditions
Smoking
Interventions
Varenicline, placebo, bupropion SR
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
506 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
3
States / cities
Minneapolis, Minnesota • Rochester, Minnesota • La Crosse, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 9, 2014 · Synced Oct 29, 2026, 2:28 AM EDT
Completed No phase listed Observational

Message Testing for Tobacco-Related Corrective Statements

NCT01282008
View directory record Official record
Conditions
Tobacco, Smoking, Communication
Interventions
Not listed
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
14 Years to 17 Years
Enrollment
627 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2011
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 20, 2019 · Synced Oct 29, 2026, 2:28 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Effect of Helpers Program On-line Training on Smoking Relapse and Social Networks

NCT05641974
View directory record Official record
Conditions
Smoking, Cigarette Smoking
Interventions
Helpers Stay Quit Training
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 99 Years
Enrollment
940 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Oct 29, 2026, 2:28 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Nicotine Receptor Levels and Smoking Cessation

NCT01788943
View directory record Official record
Conditions
Smoking Cessation, Nicotine Addiction
Interventions
Not listed
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 12, 2018 · Synced Oct 29, 2026, 2:28 AM EDT
Completed Phase 3 Interventional

Efficacy and Safety of Rimonabant as an Aid to Smoking Cessation With or Without Nicotine Patch

NCT00458718
View directory record Official record
Conditions
Smoking Cessation
Interventions
rimonabant (SR141716)
Drug
Lead sponsor
Sanofi
Industry
Eligibility
18 Years and older
Enrollment
755 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
Bridgewater, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 20, 2009 · Synced Oct 29, 2026, 2:28 AM EDT
Completed Not applicable Interventional Results available

Randomized Controlled Trial (RCT) of a Motivational Decision Support System

NCT02086162
View directory record Official record
Conditions
Schizophrenia
Interventions
Web-based motivational decision support system, NCI Education
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years to 70 Years
Enrollment
184 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
3
States / cities
Chicago, Illinois • Worcester, Massachusetts • New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Nov 29, 2018 · Synced Oct 29, 2026, 2:28 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Use and Harm Exposure in New Low Nicotine Cigarettes

NCT01202942
View directory record Official record
Conditions
Cigarette Smoking
Interventions
Quest
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
21 Years to 65 Years
Enrollment
246 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2013
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 19, 2013 · Synced Oct 29, 2026, 2:28 AM EDT