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ClinicalTrials.gov public records Last synced Oct 30, 2026, 10:58 AM EDT

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Showing 1465–1488 of 2,082 matching trials from the live ClinicalTrials.gov search.
Conditions
Tobacco Smoking, Healthy Participants, E-cigarette Smokers
Interventions
Felis Domesticus
Biological
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 50 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Conditions
Smoking Cessation, Electronic Cigarette Use, Cigarette Smoking
Interventions
Regular Nicotine patch and lozenge dose, Augmented Nicotine patch and lozenge dose
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Charleston, South Carolina
Conditions
Vaping
Interventions
Exposure to Influencer Age and Context Variations in E-Cigarette Marketing
Other
Lead sponsor
University of Southern California
Other
Eligibility
14 Years to 17 Years
Enrollment
6,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2030
U.S. locations
1
States / cities
Los Angeles, California
Completed Not applicable Interventional Accepts healthy volunteers Results available

JUUL vs. Mod E-cigarette Study

NCT04237272
Conditions
Smoking, Tobacco Use
Interventions
Pod System E-cig, Customizable Tank E-cig, Control
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years and older
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Charleston, South Carolina
Conditions
Lung Cancer
Interventions
Ultra-brief mindfulness intervention video, Forgiveness video, ACT values video
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Piscataway, New Jersey
Conditions
Tobacco Use Disorder, Alcohol Use Disorder, Drug Use Disorder, Smoking, Alcohol Drinking, Drug Abuse
Interventions
Family-Skills Training
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
Not listed
Enrollment
800 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
Minneapolis, Minnesota
Completed Phase 3 Interventional Accepts healthy volunteers

Smoking Treatment of Prisoners

NCT00110630
Conditions
Tobacco Use Cessation, Tobacco Use Disorder
Interventions
10-week smoking cessation group therapy combined with NicoDerm CQ
Behavioral
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years to 100 Years · Female only
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Richmond, Virginia
Completed Not applicable Interventional Accepts healthy volunteers

Expert System and Family Assisted Interventions for Chinese Smokers

NCT00714467
Conditions
Smoking Cessation
Interventions
Expert System Only, Family Assisted
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
1,280 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2008
U.S. locations
1
States / cities
San Francisco, California
Completed Phase 2Phase 3 Interventional Results available

Smoking Cessation & Opioid Dependence Treatment Integration

NCT02854800
Conditions
Smoking Cessation, Opioid Related Disorders
Interventions
varenicline
Drug
Lead sponsor
West Virginia University
Other
Eligibility
18 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Morgantown, West Virginia
Conditions
Smoking Cessation, Substance-Related Disorders
Interventions
Varenicline, Placebo
Drug
Lead sponsor
Albert Einstein College of Medicine
Other
Eligibility
18 Years and older
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
The Bronx, New York
Conditions
Cigarette Smoking
Interventions
contingency management, Standard of Care
Behavioral · Other
Lead sponsor
UConn Health
Other
Eligibility
18 Years and older
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Farmington, Connecticut
Conditions
Pregnancy, Smoking
Interventions
Health & Wellness Intervention, Questionnaire, Mood Management Intervention
Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
16 Years and older · Female only
Enrollment
338 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
1
States / cities
Houston, Texas
Terminated Not applicable Interventional Accepts healthy volunteers

Identifying Student Opinion Leaders to Lead E-cigarette Interventions

NCT04083469
Conditions
E-Cig Use, Adolescent Behavior
Interventions
Peer-Led Peer-Elected Intervention, Adult-Led Intervention, Peer-Led Non-Elected Intervention
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
Not listed
Enrollment
686 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
E-cigarette Use, Vaping, Nicotine Dependence
Interventions
Varenicline 1mg BID, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
326 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
2
States / cities
New Haven, Connecticut • Charleston, South Carolina
Completed Not applicable Interventional

NC Enhanced WISEWOMAN Project

NCT00288327
Conditions
Cardiovascular Disease
Interventions
Lifestyle behavior change program, Pamphlets
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
40 Years to 64 Years · Female only
Enrollment
258 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
1
States / cities
Wilmington, North Carolina
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

CONNECT Cancer Survivors With Tobacco Treatment

NCT07020273
Conditions
Tobacco Use, Tobacco Use Cessation, Smoking Cessation, Nicotine Addiction, Tobacco Smoking
Interventions
ELEVATE, ELEVATE-S
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
3,543 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
St Louis, Missouri
Conditions
Cigarette Smoking
Interventions
D-cycloserine, Nicotine Replacement Therapy (patch), Smoking Cue Exposure, Progressive Muscle Relaxation, Placebo
Drug · Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
21 Years to 55 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
New York, New York
Conditions
Smoking
Interventions
Transdermal Nicotine Patch
Drug
Lead sponsor
University of Maryland, College Park
Other
Eligibility
18 Years to 21 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
College Park, Maryland
Conditions
Nicotine Dependence
Interventions
zonisamide, placebo
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 65 Years
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Baltimore, Maryland
Completed No phase listed Observational Results available

Alpha-1 Carrier Genomics Study

NCT02810327
Conditions
Alpha-1 Antitrypsin Deficiency, Emphysema, COPD, Smoking
Interventions
Genetic Sequencing
Genetic
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Charleston, South Carolina
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Varenicline and Bupropion for Smoking Cessation

NCT00935818
Conditions
Smoking
Interventions
Varenicline, placebo, bupropion SR
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
506 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
3
States / cities
Minneapolis, Minnesota • Rochester, Minnesota • La Crosse, Wisconsin
Completed Not applicable Interventional Accepts healthy volunteers

Treating Chinese Smokers With Interactive Expert System

NCT00713895
Conditions
Smoking Cessation
Interventions
Expert System, Standard Self-Help
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
363 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2005
U.S. locations
1
States / cities
San Francisco, California
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Effects of E-Cigarette Power and Nicotine Content in Dual Users and Vapers

NCT03830892
Conditions
Electronic Cigarettes
Interventions
E-cigarette Lab Session 15 watts, 10 mg nicotine, E-cigarette Lab Session 15 watts, 30 mg nicotine, E-cigarette Lab Session 30 watts, 10 mg nicotine, E-cigarette Lab Session 30 watts, 30 mg nicotine, Own Brand Session - E-cigarette, Own Brand Session - E-cigarette/Cigarette
Other
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
21 Years to 55 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Richmond, Virginia
Conditions
Tobacco-Related Carcinoma
Interventions
Health Education, Interview, Smoking Cessation Intervention, Survey Administration, Text Message-Based Navigation Intervention
Behavioral · Other
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years to 35 Years
Enrollment
292 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Columbus, Ohio