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Showing 1–24 of 300 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Smoking Cessation Intervention Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

Smoking Relapse Prevention Via Just-in-Time-Adaptive Interventions

NCT03690596
View directory record Official record
Conditions
Smoking Cessation
Interventions
NRT + QuitBuddy, NRT + QuitBuddy-Recall, Treatment as Usual
Other
Lead sponsor
Meharry Medical College
Other
Eligibility
18 Years and older
Enrollment
94 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 12, 2021 · Synced Jun 25, 2026, 6:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Inspired: Smartphone Videogame-Based Smoking Cessation Intervention

NCT03929003
View directory record Official record
Conditions
Smoking Cessation
Interventions
Inspired
Behavioral
Lead sponsor
Rowan University
Other
Eligibility
18 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Glassboro, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 9, 2020 · Synced Jun 25, 2026, 6:42 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Incentive-based Intervention for Smoking Cessation and Prevention in High Schools

NCT01173835
View directory record Official record
Conditions
Tobacco Prevention and Cessation
Interventions
Incentives for being tobacco free
Behavioral
Lead sponsor
Yale University
Other
Eligibility
13 Years and older
Enrollment
1,651 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 3, 2012 · Synced Jun 25, 2026, 6:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Testing Different Theories of Smoking Cessation: An Intervention Study

NCT01209897
View directory record Official record
Conditions
Smoking Cessation
Interventions
Smoking cessation booklet
Behavioral
Lead sponsor
University of Hawaii
Other
Eligibility
18 Years and older
Enrollment
1,826 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated May 13, 2024 · Synced Jun 25, 2026, 6:42 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Storytelling Narrative Communication Intervention for Smoking Cessation in Women Living With HIV

NCT03289676
View directory record Official record
Conditions
HIV/AIDS
Interventions
Storytelling Narrative Intervention
Combination Product
Lead sponsor
University of Massachusetts, Boston
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 8, 2019 · Synced Jun 25, 2026, 6:42 PM EDT
Completed Not applicable Interventional

Smokefree.Gov Website in Helping United States Federal Employees Quit Smoking

NCT00245076
View directory record Official record
Conditions
Unspecified Adult Solid Tumor, Protocol Specific
Interventions
smoking cessation intervention, internet-based intervention
Behavioral · Other
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 30, 2015 · Synced Jun 25, 2026, 6:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Smoker-to-Smoker (S2S) Peer Marketing and Messaging to Disseminate Tobacco Interventions

NCT03224520
View directory record Official record
Conditions
Smoking Cessation
Interventions
Recommender CTHC, Standard CTHC, Peer Recruitment, Standard Online Recruitment
Behavioral · Other
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
1,487 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 25, 2021 · Synced Jun 25, 2026, 6:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Motivating Change in Aging Smokers

NCT05194917
View directory record Official record
Conditions
Smoking Cessation
Interventions
Older Smoker Motivational Intervention, Control Motivational Message
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
50 Years to 80 Years
Enrollment
201 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Mar 6, 2025 · Synced Jun 25, 2026, 6:42 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Optimizing Technology-Delivered Interventions for Smoking in Pregnancy: The Mommy Check-Up Study.

NCT02340624
View directory record Official record
Conditions
Tobacco Use Cessation
Interventions
Referral to SmokeFreeMoms, Quitline or Brief intervention
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 15, 2015 · Synced Jun 25, 2026, 6:42 PM EDT
Completed Phase 4 Interventional

Bupropion for Hospitalized Smokers With Acute Cardiovascular Disease

NCT00181818
View directory record Official record
Conditions
Smoking, Myocardial Infarction, Unstable Angina, Cardiovascular Disease
Interventions
bupropion SR (sustained-release)
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
248 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2003
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 15, 2005 · Synced Jun 25, 2026, 6:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Family-Based Approach To Reduce Smoking in Vietnamese Men

NCT02007707
View directory record Official record
Conditions
Tobacco Use Cessation, Healthy Eating
Interventions
Tobacco LHW, Healthy Eating
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
214 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
2
States / cities
San Jose, California • Santa Clara, California
Source: ClinicalTrials.gov public record
Updated Aug 5, 2019 · Synced Jun 25, 2026, 6:42 PM EDT
Completed Phase 2Phase 3 Interventional

Proactive Health Intervention for Tobacco Users (Get PHIT)

NCT00169260
View directory record Official record
Conditions
Smoking
Interventions
motivational counseling, placebo
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
536 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 12, 2018 · Synced Jun 25, 2026, 6:42 PM EDT
Recruiting Not applicable Interventional

Behavioral Intervention for Youth to Promote Vaping Cessation

NCT06765291
View directory record Official record
Conditions
Vaping, Vaping Teens, Nicotine Dependence
Interventions
QuitVaping, This is Quitting (TIQ)
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
14 Years to 18 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 21, 2025 · Synced Jun 25, 2026, 6:42 PM EDT
Recruiting Phase 1 Interventional

Development of a MHBC Intervention for Weight Loss and Smoking Cessation for Pre-Bariatric Surgery Patients

NCT07224087
View directory record Official record
Conditions
Obesity, Smoking Cessation, Bariatric Surgery Patients
Interventions
Naltrexone Hydrochloride, Bupropion HCl Extended Release, Cognitive-Behavioral Therapy
Drug · Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 18, 2026 · Synced Jun 25, 2026, 6:42 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Innovative Interventions for Smoking Cessation

NCT01050569
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
Nicotine Patch, VLNC Cigarette, VLNC Cigarette Plus Nicotine Patch
Drug · Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
235 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
2
States / cities
Duluth, Minnesota • Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 17, 2019 · Synced Jun 25, 2026, 6:42 PM EDT
Completed Not applicable Interventional

Implementation of a System-level Tobacco Treatment Intervention

NCT02816697
View directory record Official record
Conditions
Smoking Cessation, Lung Cancer
Interventions
CEASE, Usual Care Tobacco Treatment Services
Other
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
263 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Jun 25, 2026, 6:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Lung and Breast Cancer Prevention by an Integrated Intervention of Maternal Smoking Cessation and Breastfeeding

NCT05123118
View directory record Official record
Conditions
Smoking, Cigarette, Breastfeeding
Interventions
Integrated intervention of smoking cessation and breastfeeding, Attention placebo control
Behavioral
Lead sponsor
Xiaozhong Wen
Other
Eligibility
18 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Apr 16, 2025 · Synced Jun 25, 2026, 6:42 PM EDT
Enrolling by invitation Not applicable Interventional

Precision Prevention Strategy to Increase Uptake and Engagement in Lung Cancer Screening and Smoking Cessation Treatment

NCT05627674
View directory record Official record
Conditions
Smoking, Smoking Cessation, Tobacco Use Cessation
Interventions
Usual Care, RiskProfile-Clin, RiskProfile-Gen
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
915 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 23, 2025 · Synced Jun 25, 2026, 6:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Motivating Quitline Use Among Smokers in Treatment for Substance Use Disorders

NCT01882673
View directory record Official record
Conditions
Smoking Cessation
Interventions
Brief Computer Motivational Interviewing for Smoking Cessation, Nutrition Control
Behavioral
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 19, 2016 · Synced Jun 25, 2026, 6:42 PM EDT
Completed Not applicable Interventional

Quit and Fit: Teen Smoking Cessation

NCT01242657
View directory record Official record
Conditions
Tobacco Use Cessation
Interventions
Physical Activity Module, Not On Tobacco (N-O-T) Program
Behavioral
Lead sponsor
West Virginia University
Other
Eligibility
14 Years to 18 Years
Enrollment
236 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Nov 5, 2017 · Synced Jun 25, 2026, 6:42 PM EDT
Completed Not applicable Interventional

Cultural Adaptation and Piloting of a Smoking Cessation Intervention for Smokers With HIV

NCT03580460
View directory record Official record
Conditions
Hiv, Cigarette Smoking
Interventions
Computer delivered smoking cessation counseling
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 90 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 25, 2019 · Synced Jun 25, 2026, 6:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Quit4Health Intervention in Supporting Smoking Cessation and Preventing Smoking Initiation in Young Adults

NCT04009590
View directory record Official record
Conditions
Cigarette Smoking, Current Smoker
Interventions
Educational Intervention, Questionnaire Administration, Smoking Cessation Intervention
Other · Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years to 35 Years
Enrollment
579 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 21, 2021 · Synced Jun 25, 2026, 6:42 PM EDT
Terminated Not applicable Interventional

Peri-procedural Smoking Cessation Program in Patients With Chronic Pain

NCT04605744
View directory record Official record
Conditions
Chronic Pain, Smoking
Interventions
Smoking cessation counseling
Behavioral
Lead sponsor
The Cooper Health System
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Camden, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 25, 2022 · Synced Jun 25, 2026, 6:42 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Effectiveness of Various Smoking Cessation Therapies in Reducing Smoking in Adolescents - 1

NCT00158171
View directory record Official record
Conditions
Smoking Cessation, Tobacco Use Disorder
Interventions
Nicotine Replacement Therapies, Nicotine patch, Folic Acid
Drug · Dietary Supplement
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
13 Years to 18 Years
Enrollment
128 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2004
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 9, 2017 · Synced Jun 25, 2026, 6:42 PM EDT