Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 15, 2026, 7:40 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 217–240 of 798 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Smoking Cigarette Clear all

Conditions: Tobacco Dependence
Interventions: Varenicline, Nicotine patch, Placebo Patch, Placebo Pill; Drug · Other
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years and older
Enrollment: 1,251 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2020
U.S. locations: 2
States / cities: Madison, Wisconsin • Milwaukee, Wisconsin

Conditions: Nicotine Dependence, Other Tobacco Product, Bladder Cancer, Lung Cancer, Cancer of Head and Neck
Interventions: HALO; Device
Lead sponsor: Dartmouth-Hitchcock Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Lebanon, New Hampshire

Conditions: Tobacco Use Cessation, Perioperative/Postoperative Complications, Tobacco Smoking
Interventions: Brief behavioral intervention, SMS Program; Behavioral · Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Smoking, Tobacco Use
Interventions: Electronic Cigarette; Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 21 Years and older
Enrollment: 638 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Smoking, Cigarette Smoking, Tobacco Use
Interventions: IQOS; Other
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years to 65 Years
Enrollment: 102 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Smoking Cessation
Interventions: smoking cessation counseling, Nicotine patch, alphanumeric pager; Behavioral · Drug · Device
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years to 80 Years
Enrollment: 224 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003 – 2005
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Cigarette Smoking
Interventions: Deuterated nicotine and cotinine; Drug
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years to 65 Years
Enrollment: 70 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2012
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Electronic Cigarette Use
Interventions: Standardized research e-cigarette (SREC); Device
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 41 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Electronic Cigarette Use, Endothelial Dysfunction, Inflammation
Interventions: Placebo, Salsalate 750 MG Oral Tablet [DISALCID]; Drug
Lead sponsor: University of Iowa; Other
Eligibility: 18 Years to 24 Years
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2027
U.S. locations: 2
States / cities: Iowa City, Iowa

Conditions: Smoking
Interventions: NNC Spectrum Cigarette, VLNC Spectrum Cigarette, Moderate nicotine level e-liquid, Low nicotine level e-liquid, Tobacco Flavors, Tobacco and non-tobacco e-liquid flavors; Other
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 156 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 2
States / cities: Winston-Salem, North Carolina • Philadelphia, Pennsylvania

Conditions: Smoking, Tobacco
Interventions: 31237616, 31237617, 31237571, 31237581; Other
Lead sponsor: RAI Services Company; Industry
Eligibility: 21 Years to 65 Years
Enrollment: 1,060 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 9
States / cities: Brandon, Florida • Coral Springs, Florida • Aurora, Illinois + 5 more

Conditions: Tobacco Cigarette Smoking
Interventions: Smartphone-based intervention messages; Behavioral
Lead sponsor: Johns Hopkins Bloomberg School of Public Health; Other
Eligibility: 18 Years to 30 Years
Enrollment: 160 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Cigarette Smoker, Tobacco Use Disorder
Interventions: Behavioral Intervention, Laboratory Biomarker Analysis, Nicotine Patch, Questionnaire Administration, Smoking Cessation Intervention; Behavioral · Other · Drug
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years to 75 Years
Enrollment: 85 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2027
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Hiv, Cigarette Smoking
Interventions: Computer delivered smoking cessation counseling; Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 90 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Electronic Nicotine Delivery Systems, Tobacco Products, Cigarette Smoking
Interventions: EQUIP, Standard Care; Behavioral
Lead sponsor: University of Chicago; Other
Eligibility: 18 Years to 26 Years
Enrollment: 46 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Smoking, Cigarette, Electronic Cigarette Use
Interventions: Cue Reactivity Task, Computerized Visual Dot Probe, Choice Task; Behavioral
Lead sponsor: Brown University; Other
Eligibility: 21 Years to 34 Years
Enrollment: 82 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Smoking, Cigarette Smoking, Electronic Cigarettes
Interventions: Not listed
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years and older
Enrollment: 217 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Alcohol Abuse, Nicotine Dependence Tobacco Product
Interventions: E-cig use; Behavioral
Lead sponsor: Indiana University; Other
Eligibility: 21 Years and older
Enrollment: 35 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Tobacco Use Disorder
Interventions: Varying the nicotine content of cigarettes, Varying the nicotine content of e-cigarettes; Other
Lead sponsor: University of Vermont; Other
Eligibility: 21 Years and older
Enrollment: 308 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2028
U.S. locations: 2
States / cities: Providence, Rhode Island • Burlington, Vermont

Conditions: Tobacco Smoking
Interventions: Motivational Interviewing, Nicotine Replacement Therapy Sampling, Referral Only; Behavioral · Drug
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 18 Years to 65 Years
Enrollment: 58 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018
U.S. locations: 1
States / cities: New Brunswick, New Jersey

Conditions: Cardiovascular Risk Factor, Nicotine Dependence
Interventions: Electronic Cigarette; Other
Lead sponsor: University of California, San Francisco; Other
Eligibility: 21 Years and older
Enrollment: 16 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 2
States / cities: San Francisco, California

Conditions: Cigarette Smoking Behavior
Interventions: Culturally tailored anti-smoking messages, Non-culturally tailored interventions; Other
Lead sponsor: Abramson Cancer Center at Penn Medicine; Other
Eligibility: 18 Years to 30 Years
Enrollment: 2,214 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 2
States / cities: Stanford, California • Philadelphia, Pennsylvania

Conditions: Tobacco Use Disorder, Tobacco Smoking, Tobacco Dependence
Interventions: Cannabidiol (CBD) 800 mg, Placebo; Drug
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years to 65 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: North Hollywood, California

Conditions: Vaping
Interventions: Financial reward graphic message, Health reward graphic message, Self-efficacy graphic message, Social norms graphic message; Behavioral
Lead sponsor: University of Rochester; Other
Eligibility: 12 Years to 17 Years
Enrollment: 362 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021
U.S. locations: 1
States / cities: Rochester, New York

Search by objective public record fields.

UW Quitting Using Intensive Treatment Study (QUITS)

Evaluation of Appeal and Impact of E-Cigarettes Among Chronic Smokers With Smoking-Related Cancers

Short Messaging Service Program to Help Quit Smoking During Perioperative Period.

Clinical Outcomes of a Nationwide, Naturalistic E-Cig Trial (CONNECT)

The Effects of IQOS Use on Cigarette Smoking Behaviors

Pager-Assisted Smoking Cessation Treatment

Pharmacogenetics of Nicotine Metabolism in African-Americans

Switching Individuals in Treatment for Opioid Use Disorder Who Smoke Cigarettes to the SREC

Role of Inflammation in Vascular Phenotype Associated With E-cigarette Use

Project 2 Cigarette and E-cigarette Nicotine Content and E-liquid Flavors

A Multi-Site Study to Assess the Effect of Availability of a Heated Tobacco Product on Smoking Abstinence Among Current Primary Cigarette Smokers

Testing the Impact of Smartphone-based Messaging to Support Young Adult Smoking Cessation

Behavioral Activation Therapy and Nicotine Replacement Therapy in Increasing Smoking Cessation

Cultural Adaptation and Piloting of a Smoking Cessation Intervention for Smokers With HIV

Development of a Mobile Health Intervention for Electronic Cigarette Use Among Young Adults

Dual Use of ENDS and Combustible Cigarettes

e-Cigarette - DNA Adducts

Reactions to E-cigs and Alcohol

Nicotine Regulation for Dual Users of E-cigarettes and Cigarettes

Tobacco and Socioeconomic Disadvantage

Short-Term Cardiovascular Effects of E-Cigarettes: Influence of Device Power

Project RESIST: Increasing Resistance to Tobacco Marketing Among Young Adult Sexual Minority Women Using Inoculation Message Approaches

Cannabidiol for Reducing Cigarette Use

Graphic Messages to Prevent E-Cigarette Use Among Black and Latino Adolescents