Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 15, 2026, 8:09 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 289–312 of 798 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Smoking Cigarette Clear all

Conditions: Cigarette Smoking-Related Carcinoma
Interventions: Biospecimen Collection, Nitric Oxide Breath Test, Oscillometry, Spirometry, Survey Administration, Endothelial function; Procedure · Other
Lead sponsor: Ohio State University Comprehensive Cancer Center; Other
Eligibility: 15 Years to 25 Years
Enrollment: 182 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Smoking Cessation
Interventions: Nicotine Patch, Counseling, Smartphone, AutoSense; Drug · Behavioral · Other
Lead sponsor: H. Lee Moffitt Cancer Center and Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Cancer, Smoking Cessation
Interventions: Smoking Cessation Program; Behavioral
Lead sponsor: Boston Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Cigarette Smoking Behavior
Interventions: Constituent message with FDA and quitline, Constituent message without FDA and quitline, Littering message (Control); Behavioral
Lead sponsor: UNC Lineberger Comprehensive Cancer Center; Other
Eligibility: 18 Years to 65 Years
Enrollment: 845 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Tobacco Use, Cigarette Use
Interventions: Reduced nicotine regulatory environment, Restriction on characterizing flavors in combustible nicotine products, Restriction on characterizing flavors in noncombustible nicotine products; Behavioral
Lead sponsor: Bethany Shorey Fennell, PhD; Other
Eligibility: 18 Years and older
Enrollment: 747 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Smoking, Cigarette, Smoking Cessation
Interventions: Smoking Cessation iPad Decision Aid Tool; Behavioral
Lead sponsor: University of Florida; Other
Eligibility: 18 Years to 100 Years
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Tobacco Smoking
Interventions: Cigarettes, E-Cigarette, Nicotine Gum or Lozenge; Other
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years and older
Enrollment: 264 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2018
U.S. locations: 3
States / cities: Minneapolis, Minnesota • Buffalo, New York • Columbus, Ohio

Conditions: Tobacco Use, Tobacco Smoking, Cigarette Smoking, Smokeless Tobacco Cessation
Interventions: Electronic Cigarette, Oral Nicotine Pouch; Other
Lead sponsor: Roswell Park Cancer Institute; Other
Eligibility: 21 Years to 55 Years
Enrollment: 15 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Tobacco Use, Cigarette Smoking
Interventions: Sham rTMS, Active rTMS 10 Hz DLPFC; Device
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 22 Years to 70 Years
Enrollment: 64 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2027
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Lung Disease, Lung Disorder
Interventions: Group A, Group B, Group C, Group D, Group E; Other
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 21 Years to 85 Years
Enrollment: 13 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: New York, New York

Conditions: Smoking
Interventions: Low nicotine cigarettes; Other
Lead sponsor: University of Pennsylvania; Other
Eligibility: 21 Years to 65 Years
Enrollment: 207 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Microbiota, Lung Cancer, Oral Cancer
Interventions: Not listed
Lead sponsor: National Cancer Institute (NCI); NIH
Eligibility: 25 Years to 80 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2020
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Nicotine Dependence
Interventions: Reduced Nicotine Non-Menthol (RNC), Reduced Nicotine Menthol (RNC-Men), Conventional Nicotine Non-Menthol (CN); Other
Lead sponsor: UConn Health; Other
Eligibility: 18 Years to 45 Years · Male only
Enrollment: 118 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2019
U.S. locations: 2
States / cities: Farmington, Connecticut • Hartford, Connecticut

Conditions: Vaping, Nicotine Absorption
Interventions: E-cigarette, P4M3-1.7%, P4M3-1.7%LA, P4M3-3%LA, P4M3-4%LA; Other
Lead sponsor: Philip Morris Products S.A.; Industry
Eligibility: 21 Years to 65 Years
Enrollment: 15 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017
U.S. locations: 1
States / cities: High Point, North Carolina

Conditions: Smoking Cessation, Harm Reduction
Interventions: Varenicline, e-cigarette; Drug · Other
Lead sponsor: Rose Research Center, LLC; Industry
Eligibility: 21 Years to 65 Years
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 2
States / cities: Charlotte, North Carolina • Raleigh, North Carolina

Conditions: Cardiovascular Risk Factor, Nicotine Dependence
Interventions: Electronic Cigarette; Other
Lead sponsor: University of California, San Francisco; Other
Eligibility: 21 Years to 70 Years
Enrollment: 14 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2024
U.S. locations: 2
States / cities: San Francisco, California

Conditions: Alcohol Use Disorder, Smoking
Interventions: Oxytocin nasal spray, Placebo; Drug
Lead sponsor: Brown University; Other
Eligibility: 18 Years to 55 Years
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Smoking Cessation
Interventions: Not listed
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years to 50 Years
Enrollment: 119 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2000 – 2012
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Cigarette Smoking-Related Carcinoma
Interventions: Smartphone app-based Intervention (Actify! A app), Smartphone app-based Intervention (Actify! B app), Health Promotion and Education, Survey Administration; Behavioral · Other
Lead sponsor: Fred Hutchinson Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 1,812 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Nicotine Dependence
Interventions: mSMART; Device
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Smoking
Interventions: Message Tone, Navigation, Proactive Outreach, Testimonials; Behavioral
Lead sponsor: Kaiser Permanente; Other
Eligibility: 18 Years and older
Enrollment: 1,865 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: E-Cig Use
Interventions: E-liquid coolant (WS-3, 0.05%), E-liquid coolant (WS-3, 0.1%), E-liquid coolant (WS-3, 0.5%), E-liquid coolant (WS-3, 1.0%), E-liquid coolant (WS-3, 2.0%), E-liquid coolant (menthol, 0.05%), E-liquid coolant (menthol, 0.1%), E-liquid coolant (menthol, 0.5%), E-liquid coolant (menthol, 1.0%), E-liquid coolant (menthol, 2.0%), E-liquid coolant (WS-23, 0.05%), E-liquid coolant (WS-23, 0.1%), E-liquid coolant (WS-23, 0.5%), E-liquid coolant (WS-23, 1.0%), E-liquid coolant (WS-23, 2.0%), E-liquid coolant (WS-23, 4.0%); Other
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 31 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Electronic Cigarette Use
Interventions: E-cigarette liquid with ethanol, 1 puff, E-cigarette liquid without ethanol, 1 puff, E-cigarette liquid with ethanol, 10 puffs, E-cigarette liquid without ethanol, 10 puffs; Other
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 21 Years to 65 Years
Enrollment: 17 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Smoking
Interventions: FT21092, FT21093, FT21096, FT21097; Other
Lead sponsor: RAI Services Company; Industry
Eligibility: 21 Years to 60 Years
Enrollment: 122 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017
U.S. locations: 1
States / cities: Lakewood, Colorado

Search by objective public record fields.

Impact of E-cigarette Use on the Body

Applying mHealth to Tobacco-related Health Disparities

Mindfulness Based Smoking Cessation Program

Enhancing Source Credibility in Tobacco Regulatory Communications

Responses of Adults Smoking Nondaily and Daily in the Experimental Tobacco Marketplace

Feasibility of a Decision Aid for E-Cigarettes in Primary Care

Methods Project 4: Clinical Trial - Amended

Comparing Nicotine Delivery, Subjective Effects, and Sensory Experiences of Tobacco Users Using Oral Nicotine Products and Electronic Cigarettes [ZYN Study]

RTMS Targets Neural Circuits for Smoking Cessation

Effects of Electronic Cigarettes on Lung Biology

Nicotine Metabolism and Low Nicotine Cigarettes

Cigarette Smoking and Oral Microbiota

Manipulating Tobacco Constituents in Male Menthol Smokers

Study to Investigate the Nicotine Pharmacokinetic Profiles and Pharmacodynamic Effects of P4M3 Variants

Combination of E-cigarettes and Varenicline for Tobacco Harm Reduction

Short-Term Cardiovascular Effects of E-Cigarettes: Influence of E-Liquid pH

Alcohol and Cigarette Craving During Oxytocin Treatment

Physiological, Cognitive and Cerebral Activity Changes as a Function of Cigarette Smoking (With or Without Nicotine) and Tobacco Abstinence

A Behavioral Application for Improving Smoking Cessation Among Smokers

Stage Ib Trial of mSMART for Smoking Cessation Medication Adherence

'Questions About Quitting' Smoking Cessation Trial

Effect of Different E-cigarette Cooling Flavors on Adults' Sensory Experience TCORS 3.0

The Impact of Vaping Ethanol in the Evaluation of Impairment

CSD170303: Study to Assess Nicotine Uptake in Smokers From Electronic Cigarettes