Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 15, 2026, 10:12 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 409–432 of 798 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Smoking Cigarette Clear all

Conditions: Hazardous Drinking, Cigarette Smoking
Interventions: Naltrexone, Placebo; Drug
Lead sponsor: Brown University; Other
Eligibility: 18 Years and older
Enrollment: 150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2015
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Pulmonary Disease, Chronic Obstructive, Tobacco Smoking
Interventions: Brief advice, Single Training, Training to Competency; Behavioral
Lead sponsor: University of Kansas Medical Center; Other
Eligibility: 21 Years and older
Enrollment: 45 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Kansas City, Missouri

Conditions: Tobacco Cigarette Smoking
Interventions: Smartphone-based intervention messages; Behavioral
Lead sponsor: Johns Hopkins Bloomberg School of Public Health; Other
Eligibility: 18 Years to 30 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Nicotine Dependence
Interventions: Not listed
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 209 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Pulmonary Disease, Chronic Obstructive, E-cigarettes
Interventions: E-cigarette, Sham, Hyperpolarized 3-Helium, Gadolinium; Device · Other · Drug
Lead sponsor: Columbia University; Other
Eligibility: 21 Years to 35 Years
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: New York, New York

Conditions: Nicotine Dependence, Cigarettes
Interventions: Web + text smoking cessation intervention; Behavioral
Lead sponsor: University of Vermont; Other
Eligibility: 18 Years to 30 Years
Enrollment: 437 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020
U.S. locations: 1
States / cities: Burlington, Vermont

Conditions: Nicotine Dependence
Interventions: Nicotine gum and lozenge, Taboka, Camel Snus; Drug · Other
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years to 70 Years
Enrollment: 130 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2009
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Smoking Cessation, Tobacco Use Cessation
Interventions: SSR591813L (dianicline); Drug
Lead sponsor: Sanofi; Industry
Eligibility: 18 Years and older
Enrollment: 630 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2007
U.S. locations: 1
States / cities: Bridgewater, New Jersey

Conditions: Cigarette Smoking
Interventions: Deuterated nicotine and cotinine; Drug
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years to 65 Years
Enrollment: 43 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2013
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Implementation Science, Engagement, Patient, E Cigarette Use, Peer Support, Vaping Teens, Vaping Cessation, Parent Support
Interventions: Parents Helping Parents program; Behavioral
Lead sponsor: University of Nebraska; Other
Eligibility: 15 Years to 18 Years
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Omaha, Nebraska

Conditions: Electronic Cigarettes
Interventions: Own Brand Cigarette, ECIG 15 mg nicotine, sweetened, ECIG 15 mg nicotine, unsweet, ECIG 0 mg nicotine, sweetened, ECIG 0 mg nicotine, unsweet; Other
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 21 Years to 55 Years
Enrollment: 22 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Cigarette Smoking, Nicotine Dependence, Smoking Cessation
Interventions: High Nicotine Dose, Low Nicotine Dose; Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 21 Years and older
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Cigarette Smoking
Interventions: Tobacco-Heating Cigarette, Snus (Smokeless Tobacco), Tobacco-Burning Cigarette; Other
Lead sponsor: R.J. Reynolds Tobacco Company; Industry
Eligibility: 28 Years to 55 Years
Enrollment: 163 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2009
U.S. locations: 5
States / cities: Daytona Beach, Florida • Boise, Idaho • Portland, Oregon + 2 more

Conditions: Cigarette Smoking-Related Carcinoma, Tobacco-Related Carcinoma
Interventions: SmartQuit Smoking and Tobacco Cessation Program, Survey Administration; Behavioral · Other
Lead sponsor: Fred Hutchinson Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 99 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Cigarette Smoking-Related Carcinoma
Interventions: Smoking Cessation Intervention, Smoking Cessation Intervention (control), Medical Device Usage and Evaluation; Behavioral · Other
Lead sponsor: Roswell Park Cancer Institute; Other
Eligibility: 18 Years and older
Enrollment: 104 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Tobacco Use, Tobacco Smoking, Tobacco Use Cessation, Smoking, Smoking Cessation, Smoking, Cigarette
Interventions: Motivating Pacifika Against Cigarettes and Tobacco; Behavioral
Lead sponsor: Claremont Graduate University; Other
Eligibility: 18 Years to 30 Years
Enrollment: 278 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2015
U.S. locations: 2
States / cities: Claremont, California • Fullerton, California

Conditions: Nicotine Dependence
Interventions: varencline, placebo; Drug
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2007
U.S. locations: 1
States / cities: New York, New York

Conditions: Copd, Smoking Cessation, Nicotine Dependence, Tobacco Use, Cigarette Smoking
Interventions: Unified Protocol adapted for smoking cessation; Behavioral
Lead sponsor: Rush University Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Cigarette Smoking, Marijuana Abuse
Interventions: bupropion, transdermal nicotine patch, Nicotine polacrilex, nicotine lozenge, counseling for marijuana and smoking cessation, mobile contingency management; Drug · Behavioral
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 70 Years
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Cigarette Smoking-Related Carcinoma
Interventions: Carbon Monoxide Measurement, Nicotine Lozenge, Oral Nicotine Pouch, Nicotine Patch, Survey Administration, Check-in Phone Calls; Other
Lead sponsor: Ohio State University Comprehensive Cancer Center; Other
Eligibility: 21 Years and older
Enrollment: 1,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Electronic Cigarette Use
Interventions: Electronic Cigarette containing nicotine, Electronic Cigarette without nicotine; Device
Lead sponsor: Michigan Technological University; Other
Eligibility: 21 Years to 40 Years
Enrollment: 16 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Houghton, Michigan

Conditions: Vascular Health
Interventions: Electronic cigarette, traditional cigarette, (sham cigarette) - no actual exposure to cigarettes; Behavioral
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 18 Years to 50 Years
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: New York, New York

Conditions: Cigarette Smoking
Interventions: E-cigarette (EC), Nicotine Replacement Therapy (NRT), Harm-Reduction Counseling, Ecological Momentary Intervention (EMI) Text Messaging; Other · Behavioral
Lead sponsor: NYU Langone Health; Other
Eligibility: 21 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: Smoking
Interventions: Own Brand Cigarette, Electronic Cigarette #1, Electronic Cigarette #2, Electronic Cigarette #3, Leading U.S. Nicotine Gum; Other
Lead sponsor: R.J. Reynolds Vapor Company; Industry
Eligibility: 21 Years to 60 Years
Enrollment: 45 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Lincoln, Nebraska

Search by objective public record fields.

Naltrexone for At-Risk and Problem Drinking in Smoking Cessation Treatment

COPD E-cigarette Topography Training

Testing the Impact of Smartphone-based Messaging to Support Young Adult Smoking Cessation - Pilot

Study on Smoking Cessation and Cost Outcomes in the Duke Smoking Cessation Program

Ventilation and Pulmonary Endothelium Toxicities of E-cigarettes: A Randomized Crossover Pilot Study

Improving Smoking Cessation in Socioeconomically-Disadvantaged Young Adults

Health Effects of SLT, Cigarette Smoking, and New Tobacco Products

Efficacy and Safety of Dianicline Treatment as an Aid to Smoking Cessation in Cigarette Smokers (AMERIDIAN)

Comparison of Low Yield Cigarettes in African Americans vs. Whites

Parents Helping Parents for Youth Vaping Cessation

The Effect of Electronic Cigarette Liquid Characteristics in Smokers.

Evaluation of Low and High Nicotine Tobacco Free Nicotine Pouches

Switching From Usual Brand Cigarettes to a Tobacco-heating Cigarette or Snus

SmartQuit Program for Smoking Cessation

Evaluating the Episodic Future Thinking Intervention for Reducing Cigarette Consumption in Cigarette Smokers

Smoking Cessation for Young Adult Pacific Islanders: Motivating Pacifika Against Cigarettes and Tobacco

Study of Varencline Effects on Cigarette Smoking Reward and Craving During a Model of Brief Quit Attempt

Addressing Psychological Risk Factors Underlying Smoking Persistence in COPD Patients: The Fresh Start Study

Mobile Contingency Management for Marijuana and Tobacco Cessation

Oral Nicotine Pouches Versus Nicotine Replacement Therapy to Reduce Cigarette Use for Smokers in Rural Appalachia

Vaporized Nicotine and Autonomic Control

Investigation of the Effects of Electronic Cigarettes on Vascular Health

E-cigarettes for Harm Reduction Among Smokers With Serious Mental Illness

Comparison of Nicotine Plasma Concentrations and Subjective Effects for Three Electronic Cigarettes vs Combustible Cigarettes and Nicotine Gum