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ClinicalTrials.gov public records Last synced Nov 15, 2026, 2:20 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 529–552 of 798 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Smoking Cigarette Clear all

Conditions: Tobacco Use Disorder
Interventions: Either normal nicotine content cigarettes (15.8mg/g) or reduced nicotine content cigarettes (0.4mg/g), E-Cigarettes; Other
Lead sponsor: Brown University; Other
Eligibility: 18 Years to 70 Years
Enrollment: 326 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2023
U.S. locations: 2
States / cities: Providence, Rhode Island • Burlington, Vermont

Conditions: Lung Cancer, Blood Relatives of Patient w/Lung Cancer, Cigarette Smokers
Interventions: Not listed
Lead sponsor: National Human Genome Research Institute (NHGRI); NIH
Eligibility: 18 Years to 55 Years
Enrollment: 507 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 2
States / cities: Tampa, Florida • Durham, North Carolina

Conditions: COPD, Smoking
Interventions: Not listed
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 18 Years and older
Enrollment: 1 participant
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2015
U.S. locations: 1
States / cities: New York, New York

Conditions: Smoking Cessation, Acceptability of Health Care, Nicotine Dependence, Cigarettes
Interventions: Abstinent Contingent (AC) Re-Connect; Behavioral
Lead sponsor: Rowan University; Other
Eligibility: 18 Years and older
Enrollment: 9 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: Glassboro, New Jersey

Conditions: Tobacco Smoking, Tobacco Use
Interventions: Not listed
Lead sponsor: Altria Client Services LLC; Industry
Eligibility: 22 Years to 65 Years
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Stockbridge, Georgia

Conditions: Cigarette Smoking, E-cigarette Use
Interventions: Nicotine Content, Illegal cigarette price, E-cigarette price; Behavioral
Lead sponsor: Virginia Polytechnic Institute and State University; Other
Eligibility: 21 Years and older
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Roanoke, Virginia

Conditions: E Cig Use
Interventions: Not listed
Lead sponsor: Ohio State University Comprehensive Cancer Center; Other
Eligibility: 18 Years to 25 Years
Enrollment: 115 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Smoking, Cigarette
Interventions: Financial Incentive Treatment (FIT); Behavioral
Lead sponsor: University of Oklahoma; Other
Eligibility: 18 Years and older
Enrollment: 900 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2028
U.S. locations: 2
States / cities: Athens, Georgia • Tulsa, Oklahoma

Conditions: Cigarette Smoking
Interventions: contingency management, Standard of Care; Behavioral · Other
Lead sponsor: UConn Health; Other
Eligibility: 18 Years and older
Enrollment: 59 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Farmington, Connecticut

Conditions: Nicotine Vaping, Nicotine, Vaping
Interventions: CA35, CM35, Cig; Other
Lead sponsor: Philip Morris Products S.A.; Industry
Eligibility: 24 Years to 65 Years
Enrollment: 36 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022
U.S. locations: 1
States / cities: High Point, North Carolina

Conditions: Smoking, Cigarette, Smoking Cessation
Interventions: Varenicline, Combination nicotine patch and nicotine mini-lozenge treatment, Monetary incentives for initiating treatment, Automated tailored outreach, Care management, Wisconsin Tobacco Quit Line referral, Primary care provider referral, Untailored outreach, Multiple smoking cessation coaching calls; Drug · Behavioral · Other
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years and older
Enrollment: 210 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Smoking Behavior
Interventions: Dialectical Behavior Therapy -Skill Training brief intervention; Behavioral
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 2
States / cities: Charlotte, North Carolina • Winston-Salem, North Carolina

Conditions: E Cigarette Use
Interventions: adapted vaping cessation intervention; Behavioral
Lead sponsor: Veterans Medical Research Foundation; Other
Eligibility: 18 Years to 30 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: San Diego, California

Conditions: Smoking, Cigarette
Interventions: Pharmacy and Behavioral Health Team, Motivational Interviewing; Behavioral
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years to 89 Years
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Henrico, Virginia

Conditions: Tobacco Use
Interventions: Normal Nicotine Content Vape with all flavor e-liquids, Normal nicotine content vape with tobacco e-liquids, Low nicotine content vape with all flavor e-liquids, Low nicotine content vape with tobacco e-liquids; Other
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 21 Years and older
Enrollment: 69 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Nicotine Dependence, Smoking, Cigarette, Smoking Cessation, Smoking Behaviors, Smoking Reduction, Craving
Interventions: Isradipine, Cue Exposure; Drug · Behavioral
Lead sponsor: Jasper A. Smits; Other
Eligibility: 18 Years to 65 Years
Enrollment: 78 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Cigarette Smoking Behavior
Interventions: Culturally Tailored Anti-Smoking Messages; Other
Lead sponsor: Abramson Cancer Center at Penn Medicine; Other
Eligibility: 18 Years to 30 Years
Enrollment: 2,591 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Tobacco Dependence
Interventions: SWITCH IT, E-cig Provision Only; Behavioral · Other
Lead sponsor: Dartmouth-Hitchcock Medical Center; Other
Eligibility: 21 Years and older
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 2
States / cities: Louisville, Kentucky • Providence, Rhode Island

Conditions: Smoking, Smoking Cessation, Cessation, Smoking, Smoking Behaviors, Smoking, Cigarette
Interventions: No Interventions; Other
Lead sponsor: University of Southern California; Other
Eligibility: 18 Years to 65 Years
Enrollment: 212 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Smoking, Elective Surgery
Interventions: Decision aid; Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Nicotine Dependence
Interventions: placebo, Galantamine 8mg, Galantamine 16mg; Drug
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 55 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: West Haven, Connecticut

Conditions: Cigarette Smoking, Smoking Cessation, Depression
Interventions: Treatment as Usual, Goal2Quit + NRT Sampling; Behavioral · Combination Product
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years and older
Enrollment: 164 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: E-cigarette Use
Interventions: Live Free From E-cigarettes; Behavioral
Lead sponsor: University of Southern California; Other
Eligibility: 18 Years to 24 Years
Enrollment: 105 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Sex, Cigarette Smoking
Interventions: Abstinence and Smoking; Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years to 45 Years
Enrollment: 58 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Los Angeles, California

Search by objective public record fields.

Low Nicotine Content Cigarettes in Vulnerable Populations: Affective Disorders

Effect of Lung Cancer Diagnoses on Family Behaviors

Modulation of Genes Responsible for Cilia Length by Exposure to Cigarette Smoke

Re-Connect Application for Smoking Cessation

Room Air Levels of Harmful and Potentially Harmful Constituents After Heated Tobacco Product Use and Cigarettes

Effects of a Low Nicotine Standard and Tobacco Prices on Illegal Cigarette Purchasing

Young Adult EC Use and Respiratory Outcomes

Dyadic Financial Incentive Treatments for Dual Smoker Couples

Contingency Management and Pharmacotherapy for Smoking Cessation

Nicotine Pharmacokinetics Following Use of the P4M3 Gen 2.0 E-Cigarette Compared to Smoking Cigarettes

Health Systems Reach Interventions Project

A Novel Dialectical Behavior Therapy Brief Group Intervention for Cigarette Smoking by Patients With Cancer: An Open Clinical Trial

Adapting an Intervention for Vaping in Young Veterans

An Interprofessional Intervention to Reduce Smoking Rates

Cigarette and E-cigarette Nicotine Content in an Electronic Tobacco Marketplace (ETM)

Isradipine Enhancement of Virtual Reality Cue Exposure for Smoking Cessation

Project RESIST: Evaluating the Effects of Anti-smoking Inoculation Messages Among Young Adult Sexual Minority Women

Harm Reduction for Smokers With Mental Illness

Couples Dynamics and Smoking Cessation

Decision Aid Development for Smokers

A Study to Help People Quit Smoking.

Goal2Quit + NRT Sampling

An Online Intervention to Reduce E-cigarette Use and Susceptibility to Smoking in Young Adults

Mapping Brain Glutamate in Humans: Sex Differences in Cigarette Smokers