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ClinicalTrials.gov public records Last synced Nov 15, 2026, 7:04 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 121–144 of 798 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Smoking Cigarette Clear all

Conditions: Vaping, Preventive Psychiatry, Social Networking
Interventions: Above the Influence-Vaping (ATI-V); Behavioral
Lead sponsor: University of Rochester; Other
Eligibility: 12 Years to 18 Years
Enrollment: 3,950 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2025
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Cigarette Smoking
Interventions: MASP+, Control; Behavioral
Lead sponsor: University of Houston; Other
Eligibility: 18 Years and older
Enrollment: 76 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Cigarette Smoking, Nicotine Dependence
Interventions: Internet Smoking Cessation Web Site; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years to 90 Years
Enrollment: 146 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Cigarette Smoking
Interventions: Exclusive blu™ e-cigarette A1, Exclusive blu™ e-cigarette A2, Exclusive blu™ e-cigarette A3, Dual blu™ e-cigarette and usual brand B1, Dual blu™ e-cigarette and usual brand B2, Dual blu™ e-cigarette and usual brand B3, Nicotine product cessation C; Other
Lead sponsor: Lorillard Tobacco Company; Industry
Eligibility: 21 Years to 65 Years
Enrollment: 105 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014
U.S. locations: 1
States / cities: Lincoln, Nebraska

Conditions: Nicotine Dependence
Interventions: Nicotine; Drug
Lead sponsor: Yale University; Other
Eligibility: 21 Years to 65 Years
Enrollment: 14 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Electronic Nicotine Delivery Systems
Interventions: Influencer marketing; Behavioral
Lead sponsor: University of Southern California; Other
Eligibility: 16 Years to 17 Years
Enrollment: 1,462 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Quitting Smoking, Smoking Cessation, Smoking, Cigarette
Interventions: Text message smoking treatment, Nicotine replacement therapy sampling, Wisconsin Tobacco QuitLine Referral, Referral to Primary Care Provider, BREATHE 2 Cessation Study, Additional modalities to learn about and request treatment; Behavioral · Drug · Combination Product
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years and older
Enrollment: 12,376 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Hypertension, Tobacco Cigarette Smoking, Electronic Cigarettes, Cardiovascular
Interventions: Nicotine E-cigarette, Tobacco Cigarette; Other
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 50 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Nicotine Dependence, Electronic Cigarette Use, Cigarette Smoking
Interventions: Nicotine, Juul e-cigarette, Reduction; Drug · Device · Behavioral
Lead sponsor: University of Vermont; Other
Eligibility: 21 Years and older
Enrollment: 77 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Burlington, Vermont

Conditions: Smoking, Cigarette, Smoking Cessation, Stress, Stress, Emotional, Stress Reaction
Interventions: heart rate variability biofeedback and cognitive reappraisal, control tasks; Behavioral
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 18 Years to 65 Years · Female only
Enrollment: 70 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: New Brunswick, New Jersey

Conditions: Nicotine, E-liquid Flavors
Interventions: Nicotine 0 mg/mL, Nicotine 6 mg/mL, Nicotine 12 mg/mL, Nicotine 24 mg/mL, 'Menthol' flavor, 'Menthol/Mint' flavor, 'Green Apple' flavor, 'Watermelon' flavor, 'Unflavored'; Drug · Other
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 30 Years
Enrollment: 54 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Smoking
Interventions: Advertisement content (explicit vs. implicit), Advertisement content (true vs. misleading); Other
Lead sponsor: Abramson Cancer Center at Penn Medicine; Other
Eligibility: 21 Years to 29 Years
Enrollment: 56 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Tobacco-Related Carcinoma
Interventions: Health Education, Interview, Smoking Cessation Intervention, Survey Administration, Text Message-Based Navigation Intervention; Behavioral · Other
Lead sponsor: Ohio State University Comprehensive Cancer Center; Other
Eligibility: 18 Years to 35 Years
Enrollment: 292 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Smoking Cessation
Interventions: Impacto (Mobile App), Dejar de Fumar Asistente (Mobile App); Behavioral
Lead sponsor: University of Houston; Other
Eligibility: 18 Years to 55 Years
Enrollment: 38 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Cigarette Smoking
Interventions: Smoking counseling, Text messaging, Nicotine patch; Behavioral · Drug
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 24 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Smoking, Smoking Cessation, Tobacco Smoking, Cigarette Smoking
Interventions: Varenicline 0.5 MG, Nicotine Replacement Therapy (NRT); Drug
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years and older
Enrollment: 652 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Tobacco Dependence
Interventions: Nicotine-Containing Electronic Cigarette, Non-Nicotine Electronic Cigarette; Other
Lead sponsor: Milton S. Hershey Medical Center; Other
Eligibility: 21 Years to 70 Years
Enrollment: 105 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Hershey, Pennsylvania

Conditions: Tobacco Use
Interventions: Product A, Product B, Product C, Product D, Product E, Product F; Other
Lead sponsor: Altria Client Services LLC; Industry
Eligibility: 22 Years to 65 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024
U.S. locations: 3
States / cities: Lexington, Kentucky • Springfield, Missouri • Knoxville, Tennessee

Conditions: Cigarette Smoking
Interventions: Nicotine Patch, SPECTRUM Nicotine Research Cigarettes (0.07 mg), MCE-; Drug · Behavioral
Lead sponsor: Francis McClernon, Ph.D.; Other
Eligibility: 18 Years to 65 Years
Enrollment: 87 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Cigarette Smoking Behavior
Interventions: Graphic Warning Label, Text Warning Label; Other
Lead sponsor: University of Pennsylvania; Other
Eligibility: 21 Years to 60 Years
Enrollment: 316 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2019
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Smoking, Nicotine Dependence
Interventions: Nicotine e-cigarette, Non-nicotine e-cigarette; Other
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Cigarette Smoking
Interventions: CO-Contingent, Control condition; Behavioral
Lead sponsor: Nationwide Children's Hospital; Other
Eligibility: 13 Years to 19 Years
Enrollment: 126 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2015
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Vaping Behavior
Interventions: Control ad with dark gray product with tobacco flavor name, Dark gray product with strawberry flavor name, Colorful (strawberry color) product with strawberry flavor name, Colorful (strawberry color) product with strawberry flavor name and image, Colorful (strawberry color) product with strawberry flavor features, Colorful (strawberry color) product with strawberry flavor features and choice claim; Behavioral
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 18 Years to 30 Years
Enrollment: 3,083 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: New Brunswick, New Jersey

Conditions: Tobacco Use Disorder, Cigarette Smoking
Interventions: Sublingual tablet 4 mg versus Nicorette Lozenge 4mg; Drug
Lead sponsor: Friends Research Institute, Inc.; Other
Eligibility: 18 Years to 45 Years
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017
U.S. locations: 1
States / cities: Raleigh, North Carolina

Search by objective public record fields.

Network Intervention to Prevent Vaping

Smoking, Stress, HIV and Mobile Technology

Comparison of Internet Stop Smoking Intervention to Usual Care on Smoking Cessation at 6 Months

Characterization of Biomarkers of Tobacco Exposure, Urge-to-Smoke Following Exclusive and Dual Ad Lib Use of Electronic Cigarettes

Effects of Menthol in E-cigarettes on Smoking Behaviors

Influencer E-Cigarette and Cannabis Marketing: a Survey-Based Experiment Among Adolescents

BREATHE 2 Clinic Stop-Smoking Treatment Outreach Study

Cardiovascular Impacts of E-cigarettes Among Older Adults

E-cigarette Nicotine Study

A Cognitive Behavioral Stress Intervention for Women Who Smoke

Impact of Flavors on Nicotine Perception and Self-Administration Via E-cigarettes

Young Adults' Reactions to Low Nicotine Cigarette Advertising

Nicotine and Tobacco Message Framing to Change Smoking Behavior in Diverse Groups of Young Adult Smokers

Mobile Smoking Treatment for Spanish-speaking Latinx Smokers

Text Messaging for Smoking Cessation in College Health Clinics

STARS (Smoking Treatment And Remote Sampling) Study

Does Switching to Nicotine Containing Electronic Cigarettes Reduce Health Risk Markers

Pharmacokinetic and Subjective Effects of Heated Tobacco Products

Strengthening Instrumental Extinction to Prevent Smoking Relapse (VLNCCue)

Effects of Implicit Messaging by Cigarette Pack Color on Smoking Behaviors

Short Term Effects of Electronic Cigarettes in Tobacco Dependent Adults

Contingency Management for Smoking Abstinence With Adolescent Smokers

High Impact E-cigarette Advertisement Features

Pharmacokinetics of Nicotine Sublingual Tablets Versus Nicorette Lozenge in Healthy Smokers