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Showing 1–24 of 205 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Social Fear Clear all
Terminated Not applicable Interventional Results available

Efficacy of an Attention Guidance VR Intervention for Social Anxiety Disorder

NCT03683823
View directory record Official record
Conditions
Social Anxiety Disorder
Interventions
Attention guidance, Control intervention
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 65 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Mar 10, 2022 · Synced Jun 10, 2026, 2:56 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Evaluating the Effects of VQW-765 vs. Placebo in Performance Anxiety

NCT04800237
View directory record Official record
Conditions
Performance Anxiety
Interventions
VQW-765, Placebo
Drug
Lead sponsor
Vanda Pharmaceuticals
Industry
Eligibility
18 Years to 70 Years
Enrollment
230 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
15
States / cities
Tempe, Arizona • Beverly Hills, California • Garden Grove, California + 12 more
Source: ClinicalTrials.gov public record
Updated Mar 19, 2024 · Synced Jun 10, 2026, 2:56 PM EDT
Completed Not applicable Interventional Results available

Stepped-Care Cognitive-Behavioral Treatment for Youth With ASD and Anxiety

NCT03720795
View directory record Official record
Conditions
Cognitive Behavioral Therapy, Autism Spectrum Disorder, Anxiety Disorders, Obsessive-Compulsive Disorder, Social Anxiety Disorder, Generalized Anxiety Disorder, Specific Phobia
Interventions
Stepped Care CBT
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
4 Years to 14 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 14, 2025 · Synced Jun 10, 2026, 2:56 PM EDT
Recruiting Not applicable Interventional

Reward Processing and Exposure Therapy for Social Anxiety Disorder

NCT06776991
View directory record Official record
Conditions
Social Anxiety Disorder (Social Phobia), Public Speaking Anxiety, Anhedonia, ANXIETY DISORDERS (or Anxiety and Phobic Neuroses), Phobic Disorders
Interventions
Positive Affect Treatment - Behavioral (PAT-B), Relaxation Treatment, Exposure Therapy
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 60 Years
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Jun 10, 2026, 2:56 PM EDT
Completed Not applicable Interventional

Adaptation and Feasibility of the Community-Based Anxiety Program Tailored for Autism (CAPTA)

NCT06046170
View directory record Official record
Conditions
Anxiety, Autism Spectrum Disorder, Separation Anxiety, Generalized Anxiety Disorder, Social Anxiety Disorder of Childhood
Interventions
Cognitive Behavioral Therapy, Treatment as Usual
Behavioral · Other
Lead sponsor
Baylor College of Medicine
Other
Eligibility
7 Years to 17 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
3
States / cities
Baltimore, Maryland • Philadelphia, Pennsylvania • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Jun 10, 2026, 2:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Treatment Seeking for Social Anxiety

NCT04196296
View directory record Official record
Conditions
Social Anxiety
Interventions
Psychoeducation, Motivation
Behavioral
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
18 Years and older
Enrollment
919 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 11, 2019 · Synced Jun 10, 2026, 2:56 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research

NCT04806620
View directory record Official record
Conditions
Post-Acute COVID-19 Syndrome, ME/CFS, Rheumatic Arthritis, Juvenile Rheumatoid Arthritis (JRA), Psoriatic Arthritis (PsA), Ankylosing Spondylitis (AS), Autoimmune Encephalitis, Celiac Disease, Celiac Disease in Children, Chronic Lyme Disease, Post-treatment Lyme Disease Syndrome, Crohn's Disease, Dysautonomia, Anorexia Nervosa, Bulimia Nervosa, ARFID, Avoidant / Restrictive Food Intake Disorder, Ehlers Danlos Syndrome, Endometriosis, Fibromyalgia (FM), Long COVID, Lupus, Migraines, Mast Cell Activation Syndrome, Multiple Sclerosis, Myalgic Encephalomyelitis (ME), Myasthenia Gravis, Generalized, Myasthenia Gravis in Children, Narcolepsy, Obsessive Compulsive Disorder (OCD), PANDAS, Pediatric Acute-onset Neuropsychiatric Syndrome (PANS), POTS - Postural Orthostatic Tachycardia Syndrome, General Anxiety Disorder, Social Anxiety Disorder, PTSD - Post Traumatic Stress Disorder, Psoriasis, Traumatic Brain Injury, Tourette's Syndrome, Inflammatory Bowel Disease (IBD), Autoimmune Diseases, Neurological Diseases or Conditions, Psychiatric Disorder, Sjogren's Syndrome, Ulcerative Colitis and Crohn's Disease
Interventions
Not listed
Lead sponsor
Brain Inflammation Collaborative
Other
Eligibility
2 Years and older
Enrollment
10,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2030
U.S. locations
1
States / cities
Delafield, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Jun 10, 2026, 2:56 PM EDT
Completed Not applicable Interventional

Social Anxiety Telehealth Therapy Study

NCT04450303
View directory record Official record
Conditions
Social Anxiety
Interventions
Telehealth CBT
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Sep 22, 2021 · Synced Jun 10, 2026, 2:56 PM EDT
Completed Phase 1 Interventional

fMRI Study Comparing BOLD Activation Patterns Using GW679769 In Subjects With Social Anxiety Disorder

NCT00332046
View directory record Official record
Conditions
Social Anxiety Disorder
Interventions
GW679769
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 50 Years
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2006
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Oct 15, 2008 · Synced Jun 10, 2026, 2:56 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Using Virtual Reality in Exposure-Based Treatment for Social Anxiety in Youth

NCT03135990
View directory record Official record
Conditions
Social Anxiety, Social Anxiety Disorder, Social Anxiety Disorder of Childhood
Interventions
Cognitive Behavioral Therapy with Virtual Reality Technology
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
13 Years to 23 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 10, 2022 · Synced Jun 10, 2026, 2:56 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Social Safety Learning in the Brain Oxytocin System

NCT05968651
View directory record Official record
Conditions
Social Phobia
Interventions
Oxytocin nasal spray
Drug
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 45 Years
Enrollment
121 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 12, 2024 · Synced Jun 10, 2026, 2:56 PM EDT
Withdrawn Phase 1 Interventional

Safety, Tolerability, and Efficacy of RLS103 in Subjects With Acute Anxiety Within Social Anxiety Disorder (SAD)

NCT05429788
View directory record Official record
Conditions
Social Anxiety Disorder
Interventions
Low dose RLS103, High dose RLS103, placebo inhaled dry powder
Drug
Lead sponsor
Receptor Life Sciences
Industry
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
3
States / cities
Los Angeles, California • Oceanside, California • Torrance, California
Source: ClinicalTrials.gov public record
Updated Apr 1, 2024 · Synced Jun 10, 2026, 2:56 PM EDT
Recruiting Not applicable Interventional

Application of Virtual Reality Technology to Treatment of Social Anxiety

NCT06845488
View directory record Official record
Conditions
Autism Spectrum Disorder, Social Anxiety Disorder
Interventions
CBT, VR
Behavioral · Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 14, 2025 · Synced Jun 10, 2026, 2:56 PM EDT
Enrolling by invitation Early Phase 1 Interventional Accepts healthy volunteers

Opioids and Social Support Enhanced Extinction Effects

NCT04166071
View directory record Official record
Conditions
Fear
Interventions
Naltrexone, Placebo
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 35 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
2
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 19, 2025 · Synced Jun 10, 2026, 2:56 PM EDT
Recruiting Not applicable Interventional

CO2 Reactivity as a Biomarker of Non-Response to Exposure-Based Therapy

NCT05467683
View directory record Official record
Conditions
Obsessive-Compulsive Disorder, Post Traumatic Stress Disorder, Generalized Anxiety Disorder, Social Anxiety Disorder, Panic Disorder
Interventions
Exposure-Based Therapy
Behavioral
Lead sponsor
Jasper A. Smits
Other
Eligibility
18 Years to 70 Years
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
2
States / cities
Boston, Massachusetts • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Jun 10, 2026, 2:56 PM EDT
Withdrawn Phase 1 Interventional Accepts healthy volunteers

Adaptive Treatment Strategies for Improving Engagement With a Web-Based Smoking Intervention in Socially Anxious Smokers

NCT04260776
View directory record Official record
Conditions
Social Anxiety Disorder, Tobacco Use Disorder
Interventions
Phase 1: Web-based intervention (MyWebQuit) with 1-way text messages, Phase 1: Web-based intervention (MyWebQuit) with interactive, 2-way text messages, Phase 2: re-engagement text messages, Phase 2: re-engagement emails
Behavioral
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 7, 2021 · Synced Jun 10, 2026, 2:56 PM EDT
Active, not recruiting Phase 3 Interventional Accepts healthy volunteers

Partners in Caring for Anxious Youth

NCT04598230
View directory record Official record
Conditions
Anxiety, Separation, Anxiety, Generalized, Anxiety, Social
Interventions
Cognitive Behavioral Therapy (CBT), Combination therapy (COMB)
Behavioral · Drug
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
7 Years to 17 Years
Enrollment
468 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
3
States / cities
Los Angeles, California • Chicago, Illinois • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 17, 2025 · Synced Jun 10, 2026, 2:56 PM EDT
Completed Phase 2 Interventional

CBT for Social Anxiety Disorder Delivered by School Counselors

NCT01320800
View directory record Official record
Conditions
Social Anxiety Disorder
Interventions
Skills for Academic and Social Success, Skills for Life
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
14 Years to 17 Years
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 28, 2016 · Synced Jun 10, 2026, 2:56 PM EDT
Completed Phase 3 Interventional

P3b Short-term Study of CTN in Patients With ADHD and Comorbid Anxiety

NCT06973577
View directory record Official record
Conditions
ADHD, Anxiety, Generalized Anxiety, Social Anxiety Disorder
Interventions
Centanafadine, Placebo
Drug · Other
Lead sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
315 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
46
States / cities
Dothan, Alabama • Little Rock, Arkansas • Rogers, Arkansas + 41 more
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Jun 10, 2026, 2:56 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Generalized Anxiety Disorder and Social Anxiety Disorder: Their Impact on the Processing of Information and Learning

NCT00062517
View directory record Official record
Conditions
Anxiety Disorders
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
18 Years to 50 Years
Enrollment
497 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2016
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 5, 2017 · Synced Jun 10, 2026, 2:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Brain Response Associated With Parent-based Treatment for Childhood Anxiety Disorders

NCT03585010
View directory record Official record
Conditions
Anxiety Disorder of Childhood, Separation Anxiety Disorder of Childhood, Social Anxiety Disorder of Childhood, Generalized Anxiety Disorder
Interventions
Supportive Parenting for Anxious Childhood Emotions, Parent Educational Support, Cognitive-Behavioral Therapy
Behavioral
Lead sponsor
Yale University
Other
Eligibility
6 Years to 12 Years
Enrollment
214 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Jun 10, 2026, 2:56 PM EDT
Completed Phase 4 Interventional Results available

Improving Treatment Outcomes in Pharmacotherapy of Generalized Social Anxiety Disorder

NCT00282828
View directory record Official record
Conditions
Social Phobia
Interventions
Sertraline, Venlafaxine, Placebo, Clonazepam
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
397 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
2
States / cities
La Jolla, California • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 13, 2013 · Synced Jun 10, 2026, 2:56 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Effect of Oxytocin Nasal Sprays on Social Behavior in Social Anxiety Disorder

NCT01856530
View directory record Official record
Conditions
Social Anxiety Disorder
Interventions
Oxytocin, Placebo
Drug
Lead sponsor
Stefan G. Hofmann
Other
Eligibility
18 Years and older · Male only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 12, 2018 · Synced Jun 10, 2026, 2:56 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Social Anxiety MDMA-Assisted Therapy Investigation

NCT05138068
View directory record Official record
Conditions
Social Anxiety Disorder
Interventions
MDMA, Psychotherapy
Drug · Behavioral
Lead sponsor
Jason B Luoma
Other
Eligibility
18 Years to 65 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 27, 2025 · Synced Jun 10, 2026, 2:56 PM EDT