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Showing 1–24 of 208 matching trials from the live ClinicalTrials.gov search.
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Active, not recruiting Not applicable Interventional

Comparative Effectiveness of Internet-based Versus Parent-Coached Cognitive-Behavioral Therapy For Children and Adolescents With Anxiety and OCD

NCT07024758
View directory record Official record
Conditions
Obsessive Compulsive Disorder (OCD), Anxiety Disorder of Childhood or Adolescence, Social Anxiety Disorder of Childhood, Generalized Anxiety Disorder (GAD), Separation Anxiety Disorder, Panic Disorder, Panic Attacks, Panic Disorder (With or Without Agoraphobia), Phobia, Specific
Interventions
Parent Coached Exposure Therapy, Family Based, Internet-Based Cognitive Behavioral Therapy
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
7 Years to 17 Years
Enrollment
174 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Sep 4, 2026, 10:55 PM EDT
Completed Phase 1 Interventional

Brief Intervention for Socially Anxious College Drinkers

NCT00872118
View directory record Official record
Conditions
Alcohol Consumption, Alcohol Negative Consequences, Social Anxiety
Interventions
Brief Intervention for Socially Anxious Drinkers (BISAD), Enhanced Alcohol Skills Building and Education Program
Behavioral
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years to 26 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 15, 2010 · Synced Sep 4, 2026, 10:55 PM EDT
Completed Not applicable Interventional

WRITE: Written Imaginal Thinking Exercise Study

NCT07464158
View directory record Official record
Conditions
Anxiety, Stress, Social Anxiety
Interventions
Worst-Case Scenario Written Exposure Exercise, Neutral Future Scenario Written Exercise, Best-Case Scenario Written Exposure Exercise
Behavioral
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
18 Years and older
Enrollment
353 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Sep 4, 2026, 10:55 PM EDT
Completed Not applicable Interventional

Optimizing Exposure Therapy for Anxiety Disorders

NCT04048824
View directory record Official record
Conditions
Social Anxiety Disorder, Panic Disorder
Interventions
Inhibitory Learning-Based Exposure, Habituation-Based Exposure
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 65 Years
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2025
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 5, 2025 · Synced Sep 4, 2026, 10:55 PM EDT
Completed Phase 2 Interventional

A Study to Evaluate the Efficacy and Safety of ENX-102 in Participants With Social Anxiety Disorder

NCT07193563
View directory record Official record
Conditions
Social Anxiety Disorder (SAD)
Interventions
ENX-102, Placebo
Drug · Other
Lead sponsor
Engrail Therapeutics INC
Industry
Eligibility
18 Years to 70 Years
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
20
States / cities
Phoenix, Arizona • La Jolla, California • Los Angeles, California + 16 more
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Sep 4, 2026, 10:55 PM EDT
Not listed Not applicable Interventional

Study of Vilazodone to Treat Social Anxiety Disorder

NCT01712321
View directory record Official record
Conditions
Social Anxiety Disorder
Interventions
Vilazodone, Placebo
Drug
Lead sponsor
The Medical Research Network
Other
Eligibility
18 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 19, 2014 · Synced Sep 4, 2026, 10:55 PM EDT
Completed Not applicable Interventional

Effects of Therapeutic Mobile Game on Anxiety

NCT05240794
View directory record Official record
Conditions
Social Anxiety Disorder
Interventions
ABM-01, Digital Control
Device
Lead sponsor
Hunter College of City University of New York
Other
Eligibility
22 Years to 65 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 4, 2023 · Synced Sep 4, 2026, 10:55 PM EDT
Completed Not applicable Interventional Results available

Targeting Attention Orienting to Social Threat to Reduce Social Anxiety in Youth

NCT03932032
View directory record Official record
Conditions
Social Anxiety Disorder of Childhood
Interventions
Attention Bias Modification Treatment, Neutral Control Task
Behavioral
Lead sponsor
Florida International University
Other
Eligibility
10 Years to 14 Years
Enrollment
206 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
2
States / cities
New Haven, Connecticut • Miami, Florida
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Sep 4, 2026, 10:55 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Dose Timing of D-Cycloserine to Augment CBT for Social Anxiety Disorder

NCT02066792
View directory record Official record
Conditions
Social Anxiety Disorder
Interventions
D-Cycloserine, Placebo, Cognitive Behavioral Therapy
Drug · Behavioral
Lead sponsor
Jasper A. Smits
Other
Eligibility
18 Years to 70 Years
Enrollment
152 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
3
States / cities
Chicago, Illinois • Boston, Massachusetts • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jun 14, 2026 · Synced Sep 4, 2026, 10:55 PM EDT
Recruiting Phase 2 Interventional

A Study of NTX-1472 in Social Anxiety Disorder

NCT07323784
View directory record Official record
Conditions
Social Anxiety Disorder (SAD)
Interventions
NTX-1472, Placebo
Drug
Lead sponsor
Newleos Therapeutics, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
11
States / cities
Encino, California • Los Angeles, California • Oceanside, California + 8 more
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Sep 4, 2026, 10:55 PM EDT
Recruiting Not applicable Interventional

Testing Mechanisms of Virtual Reality Exposure Therapy for Social Anxiety

NCT07437872
View directory record Official record
Conditions
no Interaction VRET, Scripted Interactions VRET, Fully Customized Interactions VRET
Interventions
ExpandXR
Behavioral
Lead sponsor
Palo Alto University
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Sep 4, 2026, 10:55 PM EDT
Active, not recruiting Not applicable Interventional

Evaluation of Family-Based Behavioral Treatments for Youth With Anxiety and Obsessive-Compulsive Disorder

NCT05967468
View directory record Official record
Conditions
Obsessive-Compulsive Disorder in Children, Anxiety Disorder of Childhood, Social Anxiety Disorder of Childhood, Obsessive-Compulsive Disorder in Adolescence, Generalized Anxiety Disorder, Separation Anxiety, Panic Disorder, Panic Disorder With Agoraphobia, Panic Attacks
Interventions
Family Based, Internet-Based Cognitive Behavioral Therapy, Bibliotherapy, low therapist contact SPACE, Relaxation and Mentorship
Behavioral · Other
Lead sponsor
Baylor College of Medicine
Other
Eligibility
7 Years to 13 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Sep 4, 2026, 10:55 PM EDT
Completed Phase 2 Interventional Results available

Phase 2 Pilot Safety Study of MDMA-assisted Therapy for Social Anxiety in Autistic Adults

NCT02008396
View directory record Official record
Conditions
Social Anxiety in Autistic Adults
Interventions
Placebo, Midomafetamine HCl, Therapy
Drug · Behavioral
Lead sponsor
Resilient Pharmaceuticals
Industry
Eligibility
21 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Torrance, California
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Sep 4, 2026, 10:55 PM EDT
Completed Phase 3 Interventional Results available

Duloxetine for Social Anxiety Disorder: Prediction of Long Term Outcome

NCT00114127
View directory record Official record
Conditions
Anxiety Disorder
Interventions
Duloxetine, Placebo
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 9, 2014 · Synced Sep 4, 2026, 10:55 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Addressing Anxiety in 2-3-Year-Olds: A Pilot Intervention Study

NCT04039243
View directory record Official record
Conditions
Anxiety Disorder of Childhood, Fear, Shyness
Interventions
Being Brave, Parent Education
Behavioral · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
21 Months to 47 Months
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Sep 4, 2026, 10:55 PM EDT
Completed Not applicable Interventional

Treatment for Comorbid Social Anxiety and Alcohol Use Disorders.

NCT03428490
View directory record Official record
Conditions
Alcohol Use Disorder, Social Anxiety Disorder
Interventions
Fully integrated treatment, Stand-alone Intensive Outpatient Program
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 65 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 31, 2022 · Synced Sep 4, 2026, 10:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Brain Response Associated With Parent-based Treatment for Childhood Anxiety Disorders

NCT03585010
View directory record Official record
Conditions
Anxiety Disorder of Childhood, Separation Anxiety Disorder of Childhood, Social Anxiety Disorder of Childhood, Generalized Anxiety Disorder
Interventions
Supportive Parenting for Anxious Childhood Emotions, Parent Educational Support, Cognitive-Behavioral Therapy
Behavioral
Lead sponsor
Yale University
Other
Eligibility
6 Years to 12 Years
Enrollment
214 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Sep 4, 2026, 10:55 PM EDT
Completed Phase 4 Interventional Results available

Acamprosate in Alcoholics With Comorbid Anxiety or Depression

NCT00330174
View directory record Official record
Conditions
Alcohol Dependence, Major Depression, Social Anxiety Disorder, Generalized Anxiety Disorder
Interventions
Acamprosate
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 60 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
3
States / cities
Belmont, Massachusetts • New York, New York • Pickens, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 12, 2015 · Synced Sep 4, 2026, 10:55 PM EDT
Completed No phase listed Observational

Study of Anxiety and Avoidance of Others in Patients Previously Treated for Head and Neck Cancer

NCT00483639
View directory record Official record
Conditions
Anxiety Disorder, Head and Neck Cancer, Lung Cancer
Interventions
Medical chart review, Liebowitz Social Anxiety Scale and the Social Phobia and Anxiety Inventory, management of therapy complications, Structured Clinical Interview for the Diagnostic and Statistical Manual-IV SCID, Functional Assessment of Cancer Therapy-General (FACT-G)
Other · Procedure
Lead sponsor
Vanderbilt-Ingram Cancer Center
Other
Eligibility
21 Years to 70 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
2
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 14, 2013 · Synced Sep 4, 2026, 10:55 PM EDT
Withdrawn Not applicable Interventional

Waitlist-Control Trial of Smartphone (App-based) CBT for Social Anxiety Disorder (SAD), Withdrawn

NCT04622930
View directory record Official record
Conditions
Social Anxiety Disorder
Interventions
Smartphone-delivered CBT for SAD
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Sep 4, 2026, 10:55 PM EDT
Completed Not applicable Interventional

Effect of Mindfulness Meditation on Physiological Response to Unpredictable Stimuli

NCT03206437
View directory record Official record
Conditions
Anxiety Disorders, Generalized Anxiety Disorder, Social Anxiety Disorder, Panic Disorder, Post Traumatic Stress Disorder, Agoraphobia, Simple Phobia
Interventions
Mindfulness-Based Stress Reduction, Waitlist
Behavioral
Lead sponsor
Georgetown University
Other
Eligibility
18 Years to 65 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Dec 22, 2022 · Synced Sep 4, 2026, 10:55 PM EDT
Completed Phase 2 Interventional Results available

Oxytocin and Social Cognition in Schizophrenia

NCT00884897
View directory record Official record
Conditions
Social Cognition, Social Anxiety, Emotional Intelligence
Interventions
Oxytocin, Placebo
Drug
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 55 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Catonsville, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 1, 2019 · Synced Sep 4, 2026, 10:55 PM EDT
Recruiting Not applicable Interventional

Mindful Self-compassion for Anxiety and Depression: Impact of Delivery Method

NCT07028216
View directory record Official record
Conditions
Anxiety Disorders, Generalized Anxiety Disorder, Social Anxiety Disorder, Panic Disorder, Agoraphobia, Major Depressive Disorder, Persistent Depressive Disorder (Dysthymia)
Interventions
Mindful Self-Compassion
Behavioral
Lead sponsor
Georgetown University
Other
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Sep 4, 2026, 10:55 PM EDT
Completed Phase 2Phase 3 Interventional

Quetiapine in Social Anxiety Disorder

NCT00215254
View directory record Official record
Conditions
Social Anxiety Disorder
Interventions
quetiapine
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 18, 2006 · Synced Sep 4, 2026, 10:55 PM EDT