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Showing 1–24 of 112 matching trials from the live ClinicalTrials.gov search.
Terminated Phase 2 Interventional Accepts healthy volunteers Results available

Effects of Pregnenolone on Perceived Social Isolation

NCT02826577
Conditions
Perceived Social Isolation
Interventions
Pregnenolone 175mg, Pregnenolone 400mg, Placebo
Drug
Lead sponsor
University of Chicago
Other
Eligibility
21 Years to 80 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Completed Not applicable Interventional Accepts healthy volunteers

Social Functions to Promote Home-based Cognitive Training

NCT06175299
Conditions
Adherence, Treatment, Social Isolation
Interventions
Adherence Promotion With Person-centered Technology (APPT) System with Social Functions
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
65 Years to 90 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Tallahassee, Florida
Completed Not applicable Interventional Accepts healthy volunteers

Building Wealth and Health Network: A Microfinance/TANF Demonstration Project

NCT02577705
Conditions
Hunger, Child Development, Social Isolation
Interventions
Self Empowerment Groups, Financial Empowerment, Matched Savings
Behavioral
Lead sponsor
Center for Hunger-Free Communities
Other
Eligibility
18 Years and older
Enrollment
145 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Cancer, Cancer Metastatic, Neoplasms, Breast Cancer, Lung Cancer, Glioblastoma, Prostate Cancer, Gynecologic Cancer, Colorectal Cancer, Sarcoma, Kidney Cancer, Bladder Cancer, Lymphoma, Leukemia, Head and Neck Cancer, Pancreas Cancer, Multiple Myeloma, Anxiety, Social Isolation, Stress, Loneliness, Melanoma, Uterine Cancer
Interventions
Elly Mobile Phone Application
Behavioral
Lead sponsor
Gillian Gresham
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Completed No phase listed Observational Accepts healthy volunteers

Discrimination and the Brain-Gut-Microbiome (BGM) Axis

NCT05120908
Conditions
Discrimination, Racial, Social Isolation, Stress
Interventions
Not listed
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
266 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Personalized Reminder Information and Social Management System

NCT01497613
Conditions
Social Isolation, Social Support (Formal and Informal), Well-being/Quality of Life
Interventions
PRISM C: Computer Condition, PRISM B: Notebook Condition
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
65 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Miami, Florida
Conditions
Professional Fulfillment, Burnout, Social Isolation or Loneliness
Interventions
Commensality groups
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
Not listed
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Completed Not applicable Interventional Accepts healthy volunteers Results available

Stay Healthy In Nature Everyday: Family Nature Outings in a Low Income Population

NCT02623855
Conditions
Stress, Psychological, Social Isolation, Physical Activity
Interventions
Family outings, Park prescription, Pedometry, Case Management
Behavioral · Device
Lead sponsor
UCSF Benioff Children's Hospital Oakland
Other
Eligibility
4 Years and older
Enrollment
156 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Oakland, California
Conditions
Occupational Stress, Gender Related Stress, Social Isolation, Hypertension, Pre Diabetes, Diabetes, Obesity
Interventions
Sisters for Heart Health, Basic intervention
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
269 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Ellenton, Georgia
Recruiting No phase listed Observational Accepts healthy volunteers

Social Disconnection Study

NCT06705348
Conditions
Social Disconnection
Interventions
Not listed
Lead sponsor
Yale University
Other
Eligibility
55 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
New Haven, Connecticut
Completed Not applicable Interventional Accepts healthy volunteers Results available

PRISM 2.0 in Diverse Living Contexts

NCT03116399
Conditions
Social Isolation in Older Adults
Interventions
PRISM 2.0 Condition, Tablet Condition
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
65 Years and older
Enrollment
248 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
4
States / cities
Miami, Florida • Tallahassee, Florida • Atlanta, Georgia + 1 more
Completed Not applicable Interventional Accepts healthy volunteers

International Students Intervention

NCT04945902
Conditions
Social Isolation
Interventions
Synchronous Intervention, Asynchronous Intervention
Behavioral
Lead sponsor
Purdue University
Other
Eligibility
18 Years and older
Enrollment
77 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
West Lafayette, Indiana
Conditions
Critical Illness, Social Isolation, Anxiety, Depression, Post Intensive Care Unit Syndrome
Interventions
Social Engagement
Behavioral
Lead sponsor
Kirby Mayer
Other
Eligibility
18 Years to 99 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Lexington, Kentucky
Conditions
Military Family, Mental Health Disorder, Social Skills, Social Isolation, Communication, Quality of Life
Interventions
avatar-based training
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
124 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Loneliness, Mood, Quality of Life
Interventions
Proactive social robot
Device
Lead sponsor
Baycrest
Other
Eligibility
70 Years and older
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
San Francisco, California
Completed Not applicable Interventional Accepts healthy volunteers

Video Chat During Meals to Improve Nutritional Intake in Older Adults

NCT04862312
Conditions
Malnutrition, Loneliness
Interventions
VideoDine
Behavioral
Lead sponsor
Cornell University
Other
Eligibility
60 Years to 95 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Ithaca, New York
Completed Not applicable Interventional Results available

Engage Coaching for Latinos

NCT04875065
Conditions
Social Isolation, Loneliness, Caregiver Burnout
Interventions
Engage coaching
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
40 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Rochester, New York
Completed Not applicable Interventional Accepts healthy volunteers

2nd AC+: New Village Model

NCT04323176
Conditions
Aging, Hiv, Loneliness, Social Isolation
Interventions
Village Model implementation
Other
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
2
States / cities
San Diego, California
Completed Not applicable Interventional Results available

Substance Use and Loneliness

NCT05338268
Conditions
Substance Use Disorders
Interventions
CBT for Loneliness, CBT for Substance Use Disorder
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Canandaigua, New York
Conditions
Social Isolation
Interventions
CONNECTED, VET BEFRIENDING
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
264 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Indianapolis, Indiana
Completed Not applicable Interventional Accepts healthy volunteers

The Impact of a Telephone Reminiscence Program

NCT05977608
Conditions
Mental Health, Loneliness, Social Isolation
Interventions
Telephone Reminiscence Intervention
Behavioral
Lead sponsor
University of Connecticut
Other
Eligibility
60 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Storrs, Connecticut
Conditions
Disability Physical
Interventions
Intervention
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
13 Years to 19 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Birmingham, Alabama
Conditions
Apathy, Loneliness, Reminiscence Therapy
Interventions
Life Story Club
Behavioral
Lead sponsor
Montefiore Medical Center
Other
Eligibility
60 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
The Bronx, New York
Recruiting Not applicable Interventional

Engage Coaching (R33 Phase)

NCT07488559
Conditions
Social Connection, Loneliness, Suicide Ideation, Social-emotional Quality of Life
Interventions
Social Engage Coaching (S-ENG)
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
60 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Rochester, New York