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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Soft Contact Lenses Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Dynamic Change in Accommodation After Wearing Multifocal Soft Contact Lenses for Myopia Control

NCT04763694
View directory record Official record
Conditions
Myopia, Accommodation
Interventions
Multifocal soft contact lenses
Device
Lead sponsor
State University of New York College of Optometry
Other
Eligibility
8 Years to 17 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 20, 2021 · Synced Jun 11, 2026, 1:59 AM EDT
Completed Not applicable Interventional Results available

A Safety and Effectiveness Study of BL-ABT12 Multi-Purpose Solution for Use by Participants With Soft Contact Lenses

NCT03897751
View directory record Official record
Conditions
Contact Lens Wear
Interventions
ABT12 Multi-Purpose Solution, COMPLETE Multi-Purpose Solution, Sensitive Eyes® Rewetting Drops
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
252 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
17
States / cities
Birmingham, Alabama • San Diego, California • San Francisco, California + 14 more
Source: ClinicalTrials.gov public record
Updated Mar 2, 2023 · Synced Jun 11, 2026, 1:59 AM EDT
Completed Not applicable Interventional Results available

A 6-Hour Clinical Evaluation of New Daily-Wear Soft Contact Lenses

NCT03235089
View directory record Official record
Conditions
Myopia
Interventions
Test Lens, Control Lens
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 13, 2020 · Synced Jun 11, 2026, 1:59 AM EDT
Completed Not applicable Interventional Results available

Clinical Comparison of 4 Daily Disposable Soft Contact Lenses

NCT03349632
View directory record Official record
Conditions
Refractive Error
Interventions
verofilcon A contact lenses, senofilcon A contact lenses, stenfilcon A contact lenses, etafilcon A contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
3
States / cities
Maitland, Florida • Pensacola, Florida • Johns Creek, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 21, 2019 · Synced Jun 11, 2026, 1:59 AM EDT
Completed Not applicable Interventional Results available

Performance Evaluation of Reusable Contact Lenses When Worn For One Month By Habitual Soft Contact Lens Wearers

NCT06098339
View directory record Official record
Conditions
Myopia, Hyperopia
Interventions
Lens A (fanfilcon A), Lens B (lotrafilcon B)
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
2
States / cities
Ocoee, Florida • State College, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 27, 2024 · Synced Jun 11, 2026, 1:59 AM EDT
Completed Not applicable Interventional Results available

Comparison of Clinical Performance of Two Monthly Replacement Toric Soft Contact Lenses

NCT06165627
View directory record Official record
Conditions
Ametropia, Astigmatism
Interventions
Lehfilcon A toric contact lenses, Comfilcon A toric contact lenses, CLEAR CARE
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years to 45 Years
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
5
States / cities
Los Angeles, California • Oakland, California • San Francisco, California + 2 more
Source: ClinicalTrials.gov public record
Updated May 28, 2025 · Synced Jun 11, 2026, 1:59 AM EDT
Completed Not applicable Interventional Results available

A One-Week Crossover Dispensing Evaluation of New Daily Wear Soft Contact Lenses

NCT03306641
View directory record Official record
Conditions
Myopia
Interventions
Test Contact Lens, Nelfilcon A
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Sep 21, 2020 · Synced Jun 11, 2026, 1:59 AM EDT
Completed Not applicable Interventional Results available

A Multi-Center Investigation of Patient Acceptability of OPTI-FREE RepleniSH® Multi-Purpose Disinfecting Solution (MPDS)

NCT00772707
View directory record Official record
Conditions
Myopia
Interventions
Multi-Purpose Disinfecting Solution (OPTI-FREE RepleniSH), Contact Lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years to 65 Years
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Sep 6, 2012 · Synced Jun 11, 2026, 1:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Corneal Staining and Physiological Compromise After Eight Hours of Soft Contact Lens Wear

NCT01015768
View directory record Official record
Conditions
Contact Lens-induced Corneal Fluorescein Staining
Interventions
ReNu Multiplus multipurpose disinfecting solution, Control
Device
Lead sponsor
Southern California College of Optometry at Marshall B. Ketchum University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Fullerton, California
Source: ClinicalTrials.gov public record
Updated Sep 17, 2020 · Synced Jun 11, 2026, 1:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Apioc Toric/Spherical Single Vision Contact Lens

NCT03970512
View directory record Official record
Conditions
Refractive Errors
Interventions
Apioc-A and Apioc-S Contact Lenses
Device
Lead sponsor
Lentechs, LLC
Industry
Eligibility
18 Years to 35 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
2
States / cities
Athens, Ohio • Powell, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 18, 2022 · Synced Jun 11, 2026, 1:59 AM EDT
Completed No phase listed Interventional Accepts healthy volunteers Results available

Evaluating Visual Acuity and Initial Fit Performance of Two Soft Contact Lenses

NCT04954833
View directory record Official record
Conditions
Visual Acuity
Interventions
EMO-200, EMO-118
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
7 Years to 12 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 26, 2025 · Synced Jun 11, 2026, 1:59 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

LSH Silicone Hydrogel Soft Hydrophilic Contact Lens for Daily Wear

NCT01735045
View directory record Official record
Conditions
Myopia
Interventions
Lagado LSH (mangofilcon A) Soft (hydrophilic) Contact Lens, Benz 3GX (hioxifilcon B) Soft (hydrophilic) Contact Lens
Device
Lead sponsor
Szabocsik and Associates, Inc.
Industry
Eligibility
18 Years and older
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
5
States / cities
Huntington Beach, California • Honolulu, Hawaii • Oak Lawn, Illinois + 2 more
Source: ClinicalTrials.gov public record
Updated Nov 27, 2012 · Synced Jun 11, 2026, 1:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Apioc Presbyopic Contact Lens

NCT04437732
View directory record Official record
Conditions
Presbyopia, Refractive Errors
Interventions
Apioc-P and Apioc-PT Contact Lens Design
Device
Lead sponsor
Lentechs, LLC
Industry
Eligibility
40 Years to 70 Years
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
2
States / cities
Athens, Ohio • Powell, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 18, 2022 · Synced Jun 11, 2026, 1:59 AM EDT
Completed Not applicable Interventional Results available

Lens Wearing Experience and Biocompatibility of a Multi-Purpose Disinfecting Solution (MPDS)

NCT01476722
View directory record Official record
Conditions
Healthy
Interventions
OPTI-FREE PureMoist multipurpose disinfecting solution
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Nov 18, 2012 · Synced Jun 11, 2026, 1:59 AM EDT
Completed Not applicable Interventional Results available

Evaluation of Surface Refractive Index Shift of Kalifilcon A Lenses Compared to Dailies Total 1, Precision 1 and Biotrue ONEday Lenses

NCT04555031
View directory record Official record
Conditions
Habitual Soft Contact Lens Use
Interventions
kalifilcon A lenses, Dalies Total 1, Precision 1, Biotrue ONEday
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Nov 7, 2021 · Synced Jun 11, 2026, 1:59 AM EDT
Completed Not applicable Interventional Results available

DD T2 Daily Disposable Registration Trial

NCT03305770
View directory record Official record
Conditions
Myopia, Refractive Errors
Interventions
verofilcon A contact lenses, delefilcon A contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
6
States / cities
San Diego, California • Longwood, Florida • Maitland, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Feb 21, 2019 · Synced Jun 11, 2026, 1:59 AM EDT
Terminated No phase listed Observational

DAILIES TOTAL1® Soft Contact Lenses - Post-Market Clinical Follow-up Study

NCT06483113
View directory record Official record
Conditions
Myopia, Hyperopia, Presbyopia, Astigmatism
Interventions
Delefilcon A spherical soft contact lenses, Delefilcon A toric soft contact lenses, Delefilcon A multifocal soft contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
7 Years and older
Enrollment
192 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
12
States / cities
San Diego, California • Ponte Vedra Beach, Florida • West Palm Beach, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Jul 19, 2025 · Synced Jun 11, 2026, 1:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Soft Multifocal Lenses in Presbyopic Previous Contact Lens Wearers

NCT06053463
View directory record Official record
Conditions
Presbyopia
Interventions
Daily disposable multifocal soft contact lens
Device
Lead sponsor
Jennifer Fogt
Other
Eligibility
38 Years and older
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
2
States / cities
Columbus, Ohio • Granville, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 26, 2024 · Synced Jun 11, 2026, 1:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Marketed Soft Contact Lenses

NCT05201807
View directory record Official record
Conditions
Visual Acuity
Interventions
Dailies Total 1 (DT1)
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
4
States / cities
Roswell, Georgia • Westerville, Ohio • Tyler, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 14, 2023 · Synced Jun 11, 2026, 1:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study of Soft Contact Lens Use With 7 Day Extended Wear

NCT00597467
View directory record Official record
Conditions
Ametropia
Interventions
VISA (comfilcon A) Silicone Hydrogel Soft contact lens, Acuvue 2 Soft Contact Lens
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
460 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
23
States / cities
La Mesa, California • San Diego, California • Santa Monica, California + 17 more
Source: ClinicalTrials.gov public record
Updated Jul 16, 2020 · Synced Jun 11, 2026, 1:59 AM EDT
Completed Not applicable Interventional Results available

Clinical Performance Assessment of a Daily Wear Monthly Replacement Soft Silicone Hydrogel Contact Lens

NCT04055519
View directory record Official record
Conditions
Refractive Errors
Interventions
Lehfilcon A contact lenses, Comfilcon A contact lenses, Multi-purpose disinfection solution
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
3
States / cities
Maitland, Florida • Bloomington, Illinois • Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated May 12, 2021 · Synced Jun 11, 2026, 1:59 AM EDT
Completed Not applicable Interventional Results available

Evaluation of Deposits on Contact Lenses Worn Daily Wear

NCT00725153
View directory record Official record
Conditions
Refractive Error
Interventions
Balafilcon A contact lenses (PureVision), Etafilcon A contact lenses (Acuvue2)
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Aug 22, 2012 · Synced Jun 11, 2026, 1:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Toric Soft Contact Lenses Containing a Chromophore to Block High-Energy Visible Light

NCT05344560
View directory record Official record
Conditions
Visual Acuity
Interventions
soft contact lens in senofilcon A (C3) with HEVL-blocking chromophore, ACUVUE OASYS 1-Day for Astigmatism
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
126 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
10
States / cities
Jacksonville, Florida • Longwood, Florida • Maitland, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Sep 14, 2023 · Synced Jun 11, 2026, 1:59 AM EDT
Completed Not applicable Interventional Results available

Clinical Comparison of Two Daily Disposable Toric Soft Contact Lenses

NCT05483127
View directory record Official record
Conditions
Astigmatism, Ametropia, Myopia
Interventions
Verofilcon A toric soft contact lenses, Stenfilcon A toric soft contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
11
States / cities
Los Angeles, California • Longwood, Florida • Maitland, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Nov 1, 2023 · Synced Jun 11, 2026, 1:59 AM EDT