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ClinicalTrials.gov public records Last synced Oct 3, 2026, 2:33 PM EDT

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Showing 25–48 of 107 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Soft Contact Lenses Clear all
Completed Not applicable Interventional Results available

Comparison of Clinical Performance of Two Monthly Replacement Toric Soft Contact Lenses

NCT06165627
View directory record Official record
Conditions
Ametropia, Astigmatism
Interventions
Lehfilcon A toric contact lenses, Comfilcon A toric contact lenses, CLEAR CARE
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years to 45 Years
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
5
States / cities
Los Angeles, California • Oakland, California • San Francisco, California + 2 more
Source: ClinicalTrials.gov public record
Updated May 29, 2025 · Synced Oct 3, 2026, 2:33 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study of Soft Contact Lens Use With 7 Day Extended Wear

NCT00597467
View directory record Official record
Conditions
Ametropia
Interventions
VISA (comfilcon A) Silicone Hydrogel Soft contact lens, Acuvue 2 Soft Contact Lens
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
460 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
23
States / cities
La Mesa, California • San Diego, California • Santa Monica, California + 17 more
Source: ClinicalTrials.gov public record
Updated Jul 17, 2020 · Synced Oct 3, 2026, 2:33 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Examination of Myopia Progression and Soft Bifocal Contact Lens Myopia Control

NCT04080128
View directory record Official record
Conditions
Myopia
Interventions
Contact lenses
Device
Lead sponsor
Ohio State University
Other
Eligibility
10 Years to 15 Years
Enrollment
248 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
2
States / cities
Columbus, Ohio • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Oct 3, 2026, 2:33 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Two Daily Disposable Toric Soft Contact Lenses Over One Week of Wear

NCT05291936
View directory record Official record
Conditions
Ocular Physiology
Interventions
PRECISION1® for Astigmatism Contact Lenses, MyDay® Toric Soft Contact Lenses
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
5
States / cities
Jacksonville, Florida • Longwood, Florida • Vestal, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 6, 2023 · Synced Oct 3, 2026, 2:33 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Extended Depth of Focus Contact Lenses for Presbyopia

NCT05495971
View directory record Official record
Conditions
Presbyopia
Interventions
NaturalVue Multifocal
Device
Lead sponsor
Visioneering Technologies, Inc
Industry
Eligibility
45 Years to 70 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Alpharetta, Georgia
Source: ClinicalTrials.gov public record
Updated Dec 16, 2024 · Synced Oct 3, 2026, 2:33 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Delefilcon A and Verofilcon A Daily Disposable Toric Soft Contact Lenses Over One Week of Wear

NCT05502289
View directory record Official record
Conditions
Ocular Physiology
Interventions
TEST LENS, CONTROL LENS
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
6
States / cities
Longwood, Florida • Maitland, Florida • Vestal, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Nov 7, 2023 · Synced Oct 3, 2026, 2:33 PM EDT
Completed Not applicable Interventional Results available

Multi-Center Clinical Evaluation of Two Reusable Soft Contact Lenses

NCT02542072
View directory record Official record
Conditions
Myopia
Interventions
comfilcon A, samfilcon A
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years to 50 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
2
States / cities
Whittier, California • Medina, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 24, 2017 · Synced Oct 3, 2026, 2:33 PM EDT
Completed Not applicable Interventional Results available

Clinical Comparison of Two Daily Disposable Toric Soft Contact Lenses

NCT05483127
View directory record Official record
Conditions
Astigmatism, Ametropia, Myopia
Interventions
Verofilcon A toric soft contact lenses, Stenfilcon A toric soft contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
11
States / cities
Los Angeles, California • Longwood, Florida • Maitland, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Nov 2, 2023 · Synced Oct 3, 2026, 2:33 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Contact Lens and Myopia Control in Optometry School Students

NCT04334369
View directory record Official record
Conditions
Myopia, Progressive
Interventions
Proclear Single Vision Contact Lenses manufactured by CooperVision, Proclear Multifocal Contact Lenses manufactured by CooperVision
Device
Lead sponsor
Jeff Rabin
Other
Eligibility
Not listed
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 7, 2022 · Synced Oct 3, 2026, 2:33 PM EDT
Completed Not applicable Interventional Results available

A Study to Evaluate the Product Performance of a Low Add MultiFocal Soft Contact Lens

NCT01539694
View directory record Official record
Conditions
Presbyopia
Interventions
LD118033 contact lens, PureVision multifocal contact lens
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Sep 30, 2020 · Synced Oct 3, 2026, 2:33 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of an Investigational Multi-Purpose Disinfecting Solution for the Care of Soft Contact Lenses in Symptomatic Patients

NCT00382603
View directory record Official record
Conditions
Contact Lens Care
Interventions
OptiFree Multi-Purpose Disinfecting Solution
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
362 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2005
U.S. locations
1
States / cities
Highlands Ranch, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 16, 2012 · Synced Oct 3, 2026, 2:33 PM EDT
Completed No phase listed Observational

Soft Contacts Observation of Risk and Education (SCORE)

NCT03305484
View directory record Official record
Conditions
Contact Lens Complication, Contact Lens Acute Red Eye, Contact Lens Related Corneal Infiltrate (Disorder), Contact Lens-Induced Corneal Fluorescein Staining
Interventions
No intervention
Other
Lead sponsor
Southern California College of Optometry at Marshall B. Ketchum University
Other
Eligibility
18 Years to 39 Years
Enrollment
171 participants
Timeline
2017 – 2019
U.S. locations
4
States / cities
Fullerton, California • Fort Lauderdale, Florida • Columbus, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 18, 2019 · Synced Oct 3, 2026, 2:33 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Enfilcon A Soft Contact Lens When Compared to Galyfilcon A Soft Contact Lens

NCT01706770
View directory record Official record
Conditions
Ametropia
Interventions
enfilcon A, galyfilcon A
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
3
States / cities
Pismo Beach, California • San Diego, California • East Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 5, 2020 · Synced Oct 3, 2026, 2:33 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study to Evaluate the Clinical Performance of Deseyne (Vifilcon C) Daily Disposable Soft Contact Lens

NCT05927753
View directory record Official record
Conditions
Refractive Error - Myopia Bilateral
Interventions
Deseyne Daily Disposable Contact Lens (Test Device)
Device
Lead sponsor
Bruno Vision Care
Industry
Eligibility
18 Years to 40 Years
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
3
States / cities
Longwood, Florida • Pittsburg, Kansas • Warwick, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 2, 2025 · Synced Oct 3, 2026, 2:33 PM EDT
Completed No phase listed Interventional Accepts healthy volunteers Results available

Evaluating Visual Acuity and Initial Fit Performance of Two Soft Contact Lenses

NCT04954833
View directory record Official record
Conditions
Visual Acuity
Interventions
EMO-200, EMO-118
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
7 Years to 12 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 27, 2025 · Synced Oct 3, 2026, 2:33 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of an Investigational Multi-Purpose Disinfecting Solution for the Care of Silicone Hydrogel Soft Contact Lenses

NCT00382902
View directory record Official record
Conditions
Contact Lens Care
Interventions
OptiFree Multi-Purpose Disinfecting Solution
Device
Lead sponsor
Alcon Research
Industry
Eligibility
Not listed
Enrollment
233 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2005
U.S. locations
1
States / cities
Portland, Maine
Source: ClinicalTrials.gov public record
Updated Aug 16, 2012 · Synced Oct 3, 2026, 2:33 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Toric Soft Contact Lenses Containing a Chromophore to Block High-Energy Visible Light

NCT05344560
View directory record Official record
Conditions
Visual Acuity
Interventions
soft contact lens in senofilcon A (C3) with HEVL-blocking chromophore, ACUVUE OASYS 1-Day for Astigmatism
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
126 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
10
States / cities
Jacksonville, Florida • Longwood, Florida • Maitland, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Sep 15, 2023 · Synced Oct 3, 2026, 2:33 PM EDT
Completed Not applicable Interventional Results available

Evaluation of Surface Refractive Index Shift of Kalifilcon A Lenses Compared to Dailies Total 1, Precision 1 and Biotrue ONEday Lenses

NCT04555031
View directory record Official record
Conditions
Habitual Soft Contact Lens Use
Interventions
kalifilcon A lenses, Dalies Total 1, Precision 1, Biotrue ONEday
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Nov 8, 2021 · Synced Oct 3, 2026, 2:33 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Non-dispensing Fit Evaluation of Investigational Limbal Ring Soft Contact Lenses With Polyvinylpyrrolidone (PVP) in Asian Eyes

NCT02036320
View directory record Official record
Conditions
Vision Correction
Interventions
etafilcon A
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 41 Years · Female only
Enrollment
190 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
6
States / cities
Berkeley, California • Fullerton, California • New York, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 19, 2018 · Synced Oct 3, 2026, 2:33 PM EDT
Completed Not applicable Interventional Results available

Clinical Evaluation of Reusable Soft Contact Lenses

NCT06119191
View directory record Official record
Conditions
Myopia
Interventions
Control Lenses (comfilcon A with current process), Test Lenses (comfilcon A with novel process)
Device
Lead sponsor
CooperVision International Limited (CVIL)
Industry
Eligibility
18 Years and older
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
5
States / cities
Berkeley, California • Bloomington, Indiana • New York, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 8, 2025 · Synced Oct 3, 2026, 2:33 PM EDT
Completed Not applicable Interventional Results available

Clinical Characterization of an Investigational Soft Silicone Hydrogel Contact Lens

NCT04631796
View directory record Official record
Conditions
Refractive Errors
Interventions
Lehfilcon A contact lenses, Multipurpose disinfection solution
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
3
States / cities
Orlando, Florida • Bloomington, Illinois • Powell, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 12, 2022 · Synced Oct 3, 2026, 2:33 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Novel Multifocal Soft Contact Lens Study

NCT06172881
View directory record Official record
Conditions
Myopia
Interventions
Investigational Contact Lens
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 40 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated May 1, 2024 · Synced Oct 3, 2026, 2:33 PM EDT
Not yet recruiting Not applicable Interventional

Contact Lenses to Slow Myopia Progression in Adults

NCT07747311
View directory record Official record
Conditions
Myopia, Myopia Progression
Interventions
Dual Focus Soft Contact Lens, Single Vision Soft Contact Lens
Device
Lead sponsor
University of California, Berkeley
Other
Eligibility
18 Years to 30 Years
Enrollment
152 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Oct 3, 2026, 2:33 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Apioc Toric/Spherical Single Vision Contact Lens

NCT03970512
View directory record Official record
Conditions
Refractive Errors
Interventions
Apioc-A and Apioc-S Contact Lenses
Device
Lead sponsor
Lentechs, LLC
Industry
Eligibility
18 Years to 35 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
2
States / cities
Athens, Ohio • Powell, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 19, 2022 · Synced Oct 3, 2026, 2:33 PM EDT