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ClinicalTrials.gov public records Last synced Nov 12, 2026, 1:33 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–19 of 19 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Soft Tissue Augmentation Clear all

Conditions: Keratinized Tissue Augmentation Around Dental Implants
Interventions: Augmented Gingival Matrix graft, Free Gingival Graft; Device · Procedure
Lead sponsor: The Forsyth Institute; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Somerville, Massachusetts

Conditions: Alveolar Bone Loss
Interventions: INFUSE® Bone Graft; Device
Lead sponsor: Medtronic Spinal and Biologics; Industry
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 8
States / cities: Los Angeles, California • Greenwood Village, Colorado • Sarasota, Florida + 4 more

Conditions: Dental Implant, Immediate Dental Implant, Soft Tissue Augmentation
Interventions: Immediate implant, SCTG, ADM; Device · Biological
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years and older
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2021
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Facial Wrinkles
Interventions: CosmetaLife, Restylane; Device
Lead sponsor: Cosmeta; Industry
Eligibility: 18 Years and older
Enrollment: 145 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2008
U.S. locations: 5
States / cities: Tracy, California • Roswell, Georgia • Chestnut Hill, Massachusetts + 2 more

Conditions: Peri-implant Bone and Soft Tissues
Interventions: Sandwich bone augmentation, Mixed bone augmentation; Procedure
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Tooth Extraction, Immediate Implant Placement
Interventions: Xenogeneic Volume-Stable Collagen Matrix (VCMX) graft No Intervention: No Soft Tissue Augmentation, Tuberosity Connective Tissue Graft (CTG); Device · Procedure
Lead sponsor: University of Iowa; Other
Eligibility: 18 Years to 95 Years
Enrollment: 31 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Recession, Gingival
Interventions: Use of collagen matrix after subepithelial connective tissue graft harvest; Device
Lead sponsor: Hailey Bivens; Other
Eligibility: 18 Years to 65 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Dental Implants, Ceramic Implant
Interventions: Immediate dental implants placements on fresh sockets after tooth extraction; Procedure
Lead sponsor: Swiss Dental Solutions; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Englewood Cliffs, New Jersey

Conditions: Lip Augmentation
Interventions: New Dermal Filler, Device: FDA Approved Dermal Filler; Device
Lead sponsor: Galderma R&D; Industry
Eligibility: 22 Years and older
Enrollment: 273 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 14
States / cities: Encino, California • San Diego, California • Solana Beach, California + 11 more

Conditions: Lip Augmentation
Interventions: Restylane®, Non-Treatment; Device
Lead sponsor: Medicis Global Service Corporation; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 12
States / cities: San Diego, California • San Francisco, California • Santa Monica, California + 9 more

Conditions: Acellular Dermal Matrix, Alveolar Mucosa
Interventions: Phase I dental implant placement with acellular dermis, Phase II dental implant uncovery with acellular dermis; Procedure
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years to 85 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Acellular Dermal Matrix, Bone Grafting, Soft Tissue Grafting
Interventions: Guided Bone Regeneration with ADM (AlloDerm) as a barrier, Guided Bone Regeneration with Resorbable Crosslinked Collagen Matrix (Mem-Lok) as a barrier; Procedure
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years to 85 Years
Enrollment: 70 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Subjects Requiring Revision Breast Augmentation Surgery
Interventions: SERI® Surgical Scaffold; Device
Lead sponsor: Sofregen Medical, Inc.; Industry
Eligibility: 18 Years and older · Female only
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 5
States / cities: La Jolla, California • San Francisco, California • Troy, Michigan + 2 more

Conditions: Sarcoma, Neuroblastoma, Wilm's Tumor
Interventions: Tumor lysate-pulsed dendritic cell (DC) vaccine, Hematopoietic stem cell transplantation (HSCT); Biological · Other
Lead sponsor: University of Michigan Rogel Cancer Center; Other
Eligibility: Up to 30 Years
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2010
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Aging, Pain
Interventions: Evolence, Lidocaine, topical anesthetic; Device · Drug
Lead sponsor: Weinkle, Susan H., M.D.; Individual
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009
U.S. locations: 1
States / cities: Bradenton, Florida

Conditions: Edentulous
Interventions: connective tissue autograft, connective tissue allograft; Procedure
Lead sponsor: University of Louisville; Other
Eligibility: 18 Years and older
Enrollment: 27 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Louisville, Kentucky

Conditions: Implant Complication
Interventions: Vertical soft tissue augmentation; Procedure
Lead sponsor: Harvard Medical School (HMS and HSDM); Other
Eligibility: 18 Years to 99 Years
Enrollment: 28 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Soft Tissue Defect
Interventions: Soft tissue flap + Connective Tissue Graft, Soft tissue flap + Geistlich Fibro-Gide®; Procedure · Device
Lead sponsor: Geistlich Pharma AG; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2026
U.S. locations: 5
States / cities: Fullerton, California • Aurora, Colorado • Houston, Texas + 2 more

Conditions: Bone Graft; Complications, Infection or Inflammation, Ridge Deficency, Dental Implant
Interventions: Connective tissue graft at time of bone graft, Acellular Demal Matrix at time of bone graft, No soft tissue grafting at time of bone graft; Procedure
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years to 99 Years
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Birmingham, Alabama

Search by objective public record fields.

Keratinized Tissue Augmentation Using Augmented Gingival Matrix Compared to Free Gingival Graft Around Implants

Localized Alveolar Ridge Augmentation With Space Maintenance Devices

Esthetic Outcomes Following Immediate Implant Combine With Soft Tissue Augmentation

Evaluation of the Safety and Efficacy of CosmetaLife™ for the Correction of Nasolabial Folds

Sandwich vs. Mixed Bone Augmentation for Implant Placement

Ultrasound-based Imaging to Detect Early Changes of Hard and Soft Tissue Around Immediately Placed Implants With or Without Soft Tissue Augmentation

Palatal Volumetric Change Analysis Following Connective Tissue Graft With and Without Donor Site Augmentation

Zirconia Implants: Practice-based Evidence

New Dermal Filler for Lip Augmentation

Safety/Efficacy Study of Restylane® in Lip Augmentation

Assessment of Two Soft Tissue Augmentation Using Acellular Dermis Around Dental Implants

Evaluating the Barrier Function, Regenerative Capacity, and Soft Tissue Outcomes of Acellular Dermal Matrix

SERI® Surgical Scaffold for Soft Tissue Support in Revision Augmentation Surgery

A Pilot Study of Tumor Cell Vaccine for High-risk Solid Tumor Patients Following Stem Cell Transplantation

Safety and Efficacy of the Addition of 0.3% Lidocaine With EVOLENCE®

Implant Placement With Simultaneous Gum Grafting

Vertical Soft Tissue Augmentation With CTG vs ADM

Evaluation of Geistlich Fibro-Gide® in Comparison to CTG for the Treatment Around Implants

To Compare Different Soft Tissue Grafts at the Time of Lateral Ridge Augmentation Procedure.