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ClinicalTrials.gov public records Last synced Oct 30, 2026, 7:02 AM EDT

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Showing 1–24 of 34 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Soft Tissue Grafting Clear all
Completed Not applicable Interventional Results available

Expression of Angiogenic Biomarkers During Healing of Intra-Oral Soft Tissue Engineered Grafts

NCT01134081
View directory record Official record
Conditions
Gingival Recession
Interventions
CelTx™, Free Gingival Graft
Biological · Procedure
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 21, 2017 · Synced Oct 30, 2026, 7:02 AM EDT
Completed Not applicable Interventional

Evaluation of Geistlich Fibro-Gide® in Comparison to CTG for the Treatment Around Implants

NCT04703738
View directory record Official record
Conditions
Soft Tissue Defect
Interventions
Soft tissue flap + Connective Tissue Graft, Soft tissue flap + Geistlich Fibro-Gide®
Procedure · Device
Lead sponsor
Geistlich Pharma AG
Industry
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
5
States / cities
Fullerton, California • Aurora, Colorado • Houston, Texas + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 30, 2026, 7:02 AM EDT
Recruiting Phase 1Phase 2 Interventional

Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors

NCT06625190
View directory record Official record
Conditions
Neuroblastoma, Rhabdomyosarcoma, Synovial Sarcoma, Peripheral Nerve Sheath Tumors, Clear Cell Sarcoma, Alveolar Soft Part Sarcoma, Desmoplastic Small Round Cell Tumor, Chordoma, Rhabdoid Tumor, Epithelioid Sarcoma, Myoepithelial Tumor, Osteosarcoma, Ewing Sarcoma, Wilms Tumor
Interventions
Miltenyi CliniMACS Prodigy ® system, Zoledronic acid
Device · Drug
Lead sponsor
University of Florida
Other
Eligibility
6 Months to 25 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Oct 30, 2026, 7:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Implant Placement With Simultaneous Gum Grafting

NCT01431144
View directory record Official record
Conditions
Edentulous
Interventions
connective tissue autograft, connective tissue allograft
Procedure
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Feb 1, 2017 · Synced Oct 30, 2026, 7:02 AM EDT
Completed Phase 2 Interventional

Stem Cell Transplantation to Treat Systemic Mastocytosis

NCT00006413
View directory record Official record
Conditions
Mastocytosis
Interventions
Stem cell transplantation
Procedure
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
2 Years to 80 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2006
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 30, 2026, 7:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Clinical Effect of Implant Placement With a Simultaneous Soft Tissue Allograft

NCT02139748
View directory record Official record
Conditions
Dental Implants
Interventions
Dental Implant & ADM, Dental Implant & ADM & bone xenograft
Procedure
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Dec 8, 2016 · Synced Oct 30, 2026, 7:02 AM EDT
Completed No phase listed Observational

Autologous Fat Grafting in Radiated Soft Tissue Reconstruction

NCT05890196
View directory record Official record
Conditions
Breast Cancer, Radiation Fibrosis, Fat Grafting
Interventions
Not listed
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Oct 30, 2026, 7:02 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

To Compare Post-Extraction Use of a Novel Ethylenediaminetetraacetic Acid (EDTA) Post-operative Mouth Rinse and Daily Use EDTA Mouth Rinse and Standard 0.12% Chlorhexidine (CHX) Post-operative Mouth Rinse and Daily Use Essential Oil (EO) Mouth Rinse.

NCT07191262
View directory record Official record
Conditions
Extraction Sites After Removal and Bone Replacement Grafting at Extraction Sockets of Dentally Hopeless Single-rooted Teeth
Interventions
0.12% CHX and Essential Oil mouthrinse, 2.6% EDTA and 0.2% EDTA mouth rinse
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 20, 2026 · Synced Oct 30, 2026, 7:02 AM EDT
Active, not recruiting No phase listed Observational

Kerecis Case Registry for SurgiBind : Soft Tissue Reinforcement

NCT05898711
View directory record Official record
Conditions
Surgery-Complications
Interventions
Fish skin graft
Device
Lead sponsor
Kerecis Ltd.
Industry
Eligibility
18 Years to 90 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Arlington, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 31, 2024 · Synced Oct 30, 2026, 7:02 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Use of a Collagen Membrane for Soft Tissue Grafting

NCT02206009
View directory record Official record
Conditions
Localized Gingival Recession
Interventions
Collagen Membrane
Device
Lead sponsor
Lauren M. F. Syrowik
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 6, 2016 · Synced Oct 30, 2026, 7:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Implant Placement and Simultaneous Soft Tissue Grafting With Single or Double Layers of Acellular Dermal Matrix

NCT01902056
View directory record Official record
Conditions
Clinical Efficacy
Interventions
One layer allograft, Two layer allograft
Procedure
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Jul 17, 2013 · Synced Oct 30, 2026, 7:02 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Vertical Soft Tissue Augmentation With CTG vs ADM

NCT05729607
View directory record Official record
Conditions
Implant Complication
Interventions
Vertical soft tissue augmentation
Procedure
Lead sponsor
Harvard Medical School (HMS and HSDM)
Other
Eligibility
18 Years to 99 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 18, 2025 · Synced Oct 30, 2026, 7:02 AM EDT
Recruiting Not applicable Interventional

Autologous Fresh Fat Grafting Followed by Autologous Cryopreserved Fat Grafting

NCT06747715
View directory record Official record
Conditions
Facial Defect
Interventions
Serial Fat Grafting Fresh followed by Cryopreserved Fat
Procedure
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 7, 2026 · Synced Oct 30, 2026, 7:02 AM EDT
Completed Not applicable Interventional Results available

A Study to Evaluate the Results of Facial Soft Tissue Reconstruction in Patients Who Have Suffered Traumatic Injury

NCT01345591
View directory record Official record
Conditions
Facial Injuries, Adipose Tissue
Interventions
Fat Grafting
Procedure
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 11, 2017 · Synced Oct 30, 2026, 7:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Clinical Effects of Hard and Soft Tissue Grafting With Dental Implants

NCT03580811
View directory record Official record
Conditions
Dental Implants
Interventions
Dental Implant &ADMG, Dental implant & ADMG & BDX
Device
Lead sponsor
University of Louisville
Other
Eligibility
18 Years to 90 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 3, 2021 · Synced Oct 30, 2026, 7:02 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Assessment of Two Soft Tissue Augmentation Using Acellular Dermis Around Dental Implants

NCT07512245
View directory record Official record
Conditions
Acellular Dermal Matrix, Alveolar Mucosa
Interventions
Phase I dental implant placement with acellular dermis, Phase II dental implant uncovery with acellular dermis
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 30, 2026, 7:02 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Evaluating the Barrier Function, Regenerative Capacity, and Soft Tissue Outcomes of Acellular Dermal Matrix

NCT07613047
View directory record Official record
Conditions
Acellular Dermal Matrix, Bone Grafting, Soft Tissue Grafting
Interventions
Guided Bone Regeneration with ADM (AlloDerm) as a barrier, Guided Bone Regeneration with Resorbable Crosslinked Collagen Matrix (Mem-Lok) as a barrier
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 85 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 23, 2026 · Synced Oct 30, 2026, 7:02 AM EDT
Not listed No phase listed Observational

Short Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds

NCT03872544
View directory record Official record
Conditions
Wound; Head, Multiple, Wound; Head, Scalp, Wound; Head, Wound Infection, Wound Complication, Wound Dehiscence, Wound of Skin, Wound Open, Wounds, Penetrating, Wounds, Nonpenetrating, Wounds and Injuries, Wounds, Disturbance of Wound Healing, Facial Bones Fracture, Soft Tissue Injuries, Skull Fractures, Surgical Wound, Surgical Wound Infection, Wound Healing
Interventions
Not listed
Lead sponsor
Dufresne, Craig, MD, PC
Other
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Fairfax, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 16, 2022 · Synced Oct 30, 2026, 7:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Volumetric Analysis of Soft and Hard Tissue Healing for Ridge Preservation and Socket Seal After Tooth Extraction

NCT02844569
View directory record Official record
Conditions
Tooth Extraction
Interventions
Xenograft bone substitute, Collagen dressing, 3D-collagen matrix
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 80 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 6, 2019 · Synced Oct 30, 2026, 7:02 AM EDT
Terminated No phase listed Observational

Localized Alveolar Ridge Augmentation With Space Maintenance Devices

NCT00991432
View directory record Official record
Conditions
Alveolar Bone Loss
Interventions
INFUSE® Bone Graft
Device
Lead sponsor
Medtronic Spinal and Biologics
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
8
States / cities
Los Angeles, California • Greenwood Village, Colorado • Sarasota, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Feb 17, 2012 · Synced Oct 30, 2026, 7:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Randomized Control Trial Testing Connective Tissue Grafts vs. Allograft on Dental Implants

NCT01934530
View directory record Official record
Conditions
Dental Implant Soft Tissue Defects in the Anterior Maxilla
Interventions
Soft Tissue Grafting
Procedure
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 10, 2017 · Synced Oct 30, 2026, 7:02 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Collagen Matrix + rhPDGF-BB vs Connective Tissue Graft for the Treatment of Peri-implant Soft Tissue Dehiscences

NCT05576922
View directory record Official record
Conditions
Implant Complication
Interventions
Prosthetic-surgical approach + autogenous graft, Prosthetic-surgical approach + graft substitute
Other
Lead sponsor
Harvard Medical School (HMS and HSDM)
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 10, 2025 · Synced Oct 30, 2026, 7:02 AM EDT
Recruiting Not applicable Interventional

Patient-reported Outcomes of Donor Site Healing Using Different Palatal Protection Techniques

NCT06892496
View directory record Official record
Conditions
Mucosal Erosion, Gingival Recession
Interventions
Visual Analog scale (VAS) questionnaire, Vacuum-formed retainer (VFR) technique, 3-D printed acrylic resin stent (3DS) technique, Flowable resin composite stent (FRC) technique, Photographs of the patient's palate, Measuring graft dimensions, Chairside Polymer Stent
Other
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Oct 30, 2026, 7:02 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Palatal Volumetric Change Analysis Following Connective Tissue Graft With and Without Donor Site Augmentation

NCT05961566
View directory record Official record
Conditions
Recession, Gingival
Interventions
Use of collagen matrix after subepithelial connective tissue graft harvest
Device
Lead sponsor
Hailey Bivens
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 19, 2024 · Synced Oct 30, 2026, 7:02 AM EDT