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Showing 1–18 of 18 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Somatic Pain Clear all
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Investigation of Low-intensity Focused Ultrasound Pressure

NCT06343883
View directory record Official record
Conditions
Somatic Pain
Interventions
low-intensity focused ultrasound - low pressure, low-intensity focused ultrasound - medium pressure, low-intensity focused ultrasound - high pressure
Device
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
18 Years to 65 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 14, 2025 · Synced Jul 22, 2026, 2:04 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Natural History of Upper Trapezius Myofascial Trigger Points: Comparison of Local and Remote Tissue Milieu in Normal Muscle, Latent and Active Myofascial Trigger Points Over Time

NCT00042276
View directory record Official record
Conditions
Neck Pain
Interventions
Not listed
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
21 Years to 65 Years
Enrollment
88 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2013
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 5, 2017 · Synced Jul 22, 2026, 2:04 PM EDT
Completed Not applicable Interventional

Stress and Health Interview for Primary Care Patients With Medically Unexplained Symptoms

NCT02151500
View directory record Official record
Conditions
Somatoform Disorders
Interventions
Stress and Health Interview
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 80 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Rochester Hills, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 7, 2015 · Synced Jul 22, 2026, 2:04 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Human Behaviors Related to the Expectation of Pain

NCT03739645
View directory record Official record
Conditions
Fear Pain
Interventions
Skin conductance levels and slopes over time in conditioned fear as metrics.as metrics for anxiety
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
16 Years to 88 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 24, 2025 · Synced Jul 22, 2026, 2:04 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Strain-Counterstrain Treatment of Piriformis Pain

NCT05023005
View directory record Official record
Conditions
Low Back Pain, Mechanical, Piriformis Syndrome, Somatic Dysfunction of Sacral Region (Finding)
Interventions
Strain-Counterstrain treatment of piriformis muscle
Other
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Jul 22, 2026, 2:04 PM EDT
Terminated Not applicable Interventional Results available

Effects of Neuro-Stim System on Pain, Sleep, and Opioid Use

NCT02673684
View directory record Official record
Conditions
Pain (Visceral, Somatic, or Neuropathic)
Interventions
Experimental NSS, Sham NSS
Device
Lead sponsor
Defense and Veterans Center for Integrative Pain Management
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated May 26, 2020 · Synced Jul 22, 2026, 2:04 PM EDT
Completed Phase 3 Interventional Results available

Safety Study of HZT-501 in Patients Who Require Long-Term Daily Non-steroidal Anti-inflammatory Drug Treatment

NCT00984815
View directory record Official record
Conditions
Osteoarthritis, Rheumatoid Arthritis, Chronic Low Back Pain, Chronic Regional Pain Syndrome, Chronic Soft Tissue Pain
Interventions
HZT-501
Drug
Lead sponsor
Amgen
Industry
Eligibility
40 Years to 80 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
4
States / cities
Chicago, Illinois • Morton Grove, Illinois • Duncansville, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Dec 17, 2024 · Synced Jul 22, 2026, 2:04 PM EDT
Completed Not applicable Interventional

Efficacy & Safety Study of Natural Eggshell Membrane (NEM) for the Treatment of Joint & Connective Tissue Disorders

NCT00750854
View directory record Official record
Conditions
Osteoarthritis, Fibromyalgia
Interventions
NEM Formulation X, NEM Formulation Y
Dietary Supplement
Lead sponsor
ESM Technologies, LLC
Industry
Eligibility
18 Years to 100 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2004
U.S. locations
1
States / cities
Jenks, Oklahoma
Source: ClinicalTrials.gov public record
Updated Sep 6, 2023 · Synced Jul 22, 2026, 2:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Expectations on Negative Affect, Perceived Cognitive Effort, and Pain

NCT05425563
View directory record Official record
Conditions
Placebo, Expectations
Interventions
Pain Expectancy Cues, Vicarious Pain Expectancy Cues, Cognitive Effort Expectancy Cues
Behavioral
Lead sponsor
Trustees of Dartmouth College
Other
Eligibility
18 Years to 55 Years
Enrollment
133 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Hanover, New Hampshire
Source: ClinicalTrials.gov public record
Updated Nov 29, 2023 · Synced Jul 22, 2026, 2:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Osteopathic Manipulative Treatment for Back Pain

NCT03892759
View directory record Official record
Conditions
Back Pain, Lumbar Pain, Thoracic Pain, Somatic Dysfunction, Fascial Distortion
Interventions
Osteopathic Manipulative Therapy
Other
Lead sponsor
Pacific Northwest University of Health Sciences
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Yakima, Washington
Source: ClinicalTrials.gov public record
Updated Apr 27, 2022 · Synced Jul 22, 2026, 2:04 PM EDT
Completed Phase 3 Interventional Results available

Double-Blind Follow-on Safety Study of HZT-501 (Ibuprofen 800 mg/Famotidine 26.6 mg) in Subjects Who Have Completed Participation in HZ-CA-301 (NCT00450658) or HZ-CA-303 (NCT00450216)

NCT00613106
View directory record Official record
Conditions
Osteoarthritis, Rheumatoid Arthritis, Chronic Low Back Pain, Chronic Regional Pain Syndrome, Chronic Soft Tissue Pain
Interventions
HZT-501, Ibuprofen
Drug
Lead sponsor
Amgen
Industry
Eligibility
40 Years to 81 Years
Enrollment
179 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Dec 16, 2024 · Synced Jul 22, 2026, 2:04 PM EDT
Completed Not applicable Interventional

Somatic Yoga and Meditation for Cancer Survivors With Pain From Neuropathy

NCT03786055
View directory record Official record
Conditions
Cancer Survivor, Pain, Chemotherapy Induced Peripheral Neuropathy, Function, Fall Risk, Balance, Quality of Life
Interventions
Somatic Yoga and Meditation (SYM)
Behavioral
Lead sponsor
Stockton University
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
2
States / cities
Atlantic City, New Jersey • Pomona, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 14, 2019 · Synced Jul 22, 2026, 2:04 PM EDT
Terminated No phase listed Observational Results available

Severity Postoperative Pain Prediction

NCT00638404
View directory record Official record
Conditions
Anxiety, Pain, Postoperative Pain
Interventions
Not listed
Lead sponsor
Wake Forest University
Other
Eligibility
18 Years and older · Female only
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 5, 2018 · Synced Jul 22, 2026, 2:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study to Evaluate the Safety and Efficacy of a Proprietary "Joint Health" Dietary Supplement in Subjects With Joint and Connective Tissue Pain

NCT03209895
View directory record Official record
Conditions
Joint Pain
Interventions
Joint Health Product, Placebo, Glucosamine / Chondroitin
Dietary Supplement
Lead sponsor
U.S. Nutraceuticals, LLC
Industry
Eligibility
18 Years to 80 Years
Enrollment
135 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Sausalito, California
Source: ClinicalTrials.gov public record
Updated Jul 5, 2017 · Synced Jul 22, 2026, 2:04 PM EDT
Completed No phase listed Observational

ADVANCE: Assessment for Defining Variability in Anesthesia Through Novel Clinical EEG

NCT00689130
View directory record Official record
Conditions
Pain
Interventions
Not listed
Lead sponsor
Medtronic - MITG
Industry
Eligibility
18 Years to 80 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
3
States / cities
Atlanta, Georgia • Louisville, Kentucky • New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 6, 2012 · Synced Jul 22, 2026, 2:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Optical Measurements of the Skin Surface to Infer Distinctions in Myofascial Tissue Stiffness

NCT06390085
View directory record Official record
Conditions
Tissue Pain
Interventions
Soft tissue manipulation
Other
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 75 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 12, 2026 · Synced Jul 22, 2026, 2:04 PM EDT
Completed Phase 4 Interventional

Relaxation Response Training for the Treatment of Rheumatoid Arthritis

NCT00056667
View directory record Official record
Conditions
Rheumatoid Arthritis
Interventions
Relaxation response and cognitive behavioral therapy, Relaxation response, RA education
Behavioral · Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 75 Years
Enrollment
168 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2006
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 16, 2014 · Synced Jul 22, 2026, 2:04 PM EDT
Terminated Not applicable Interventional

OMT of Somatic Dysfunction and Chronic Low Back Pain in Patients With Type 2 Diabetes Mellitus

NCT02054650
View directory record Official record
Conditions
Chronic Low Back Pain, Type 2 Diabetes Mellitus
Interventions
Osteopathic Manual Treatment (OMT), Sham OMT
Other
Lead sponsor
University of North Texas Health Science Center
Other
Eligibility
18 Years to 79 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated May 25, 2016 · Synced Jul 22, 2026, 2:04 PM EDT