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Showing 1–24 of 625 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Speech Clear all
Recruiting No phase listed Observational

The eXtroardinarY Babies Study: Natural History of Health and Neurodevelopment in Infants and Young Children With Sex Chromosome Trisomy

NCT03396562
View directory record Official record
Conditions
Klinefelter Syndrome, Trisomy X, XYY Syndrome, XXXY and XXXXY Syndrome, Xxyy Syndrome, Xyyy Syndrome, Xxxx Syndrome, Xxxxx Syndrome, Xxxyy Syndrome, Xxyyy Syndrome, Xyyyy Syndrome, Male With Sex Chromosome Mosaicism
Interventions
Assessments of Development and Growth
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
6 Weeks to 13 Months
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2028
U.S. locations
2
States / cities
Aurora, Colorado • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 8, 2024 · Synced Jun 7, 2026, 5:53 AM EDT
Completed Not applicable Interventional

A Comparison of the Blom Low Profile Voice Inner Cannula and the Passy-Muir One-Way Tracheotomy Tube Speaking Valve on Voice Production, Speech Intelligibility, and Biomechanical Swallowing Behavior

NCT01784224
View directory record Official record
Conditions
Mechanical Complication of Tracheostomy
Interventions
Blom Low Profile Voice Cannula/Passty-Muir Speaking Valves
Procedure
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 12, 2014 · Synced Jun 7, 2026, 5:53 AM EDT
Withdrawn Phase 1 Interventional Accepts healthy volunteers

The Effects of Tactile Speech Feedback on Stuttering Frequency

NCT01315730
View directory record Official record
Conditions
Stuttering
Interventions
Tactile Stimulation
Device
Lead sponsor
University of Mississippi, Oxford
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2011
U.S. locations
1
States / cities
University, Mississippi
Source: ClinicalTrials.gov public record
Updated May 11, 2014 · Synced Jun 7, 2026, 5:53 AM EDT
Completed Not applicable Interventional

Enhancing Reading Recovery in Aphasia With tDCS and Phonomotor Therapy

NCT06891638
View directory record Official record
Conditions
Stroke, Aphasia
Interventions
Schedule of tDCS administration
Device
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 80 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
West Orange, New Jersey • Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Jun 7, 2026, 5:53 AM EDT
Completed Phase 1Phase 2 Interventional

OTO-413 in Subjects With Speech-in-Noise Hearing Impairment

NCT04129775
View directory record Official record
Conditions
Sensorineural Hearing Loss
Interventions
OTO-413, Placebo
Drug
Lead sponsor
Otonomy, Inc.
Industry
Eligibility
21 Years to 64 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
8
States / cities
Colorado Springs, Colorado • Hollywood, Florida • Miami, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Oct 26, 2022 · Synced Jun 7, 2026, 5:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Application of Ideal Binary Masking to Disordered Speech

NCT05244603
View directory record Official record
Conditions
Hearing Loss, Sensorineural, Dysarthria
Interventions
Ideal binary mask
Behavioral
Lead sponsor
Utah State University
Other
Eligibility
18 Years to 90 Years
Enrollment
435 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Logan, Utah
Source: ClinicalTrials.gov public record
Updated Mar 25, 2025 · Synced Jun 7, 2026, 5:53 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Neural Networks and Language Recovery in Aphasia From Stroke: fMRI Studies

NCT00467103
View directory record Official record
Conditions
Aphasia, Nonfluent Aphasia, Stroke
Interventions
Not listed
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
45 Years to 80 Years
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1999 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 23, 2022 · Synced Jun 7, 2026, 5:53 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Cochlear Implants in Young Children With SSD

NCT05775367
View directory record Official record
Conditions
Single Sided Deafness, Unilateral Deafness, Hearing Loss, Unilateral, Hearing Loss, Congenital Hearing Loss, Deafness One Ear
Interventions
Cochlear Implant
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
7 Months to 71 Months
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2030
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 28, 2025 · Synced Jun 7, 2026, 5:53 AM EDT
Recruiting Not applicable Interventional

Internet-based Talking About Risk and Adolescent Choices: Health and Emotion Regulation Options

NCT06894277
View directory record Official record
Conditions
Risky Sexual Behavior, Emotion Regulation, Adolescent Behavior
Interventions
iTRAC-HERO
Behavioral
Lead sponsor
Klein Buendel, Inc.
Industry
Eligibility
12 Years to 14 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Golden, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Jun 7, 2026, 5:53 AM EDT
Completed Phase 4 Interventional Results available

Open-Label, Randomized Study Evaluating Treatment With Venlafaxine Extended-Release Plus Dialogues Time to Talk Program

NCT00401726
View directory record Official record
Conditions
Depressive Disorder, Major
Interventions
Venlafaxine ER, Dialogues Time to Talk Program
Drug · Behavioral
Lead sponsor
Wyeth is now a wholly owned subsidiary of Pfizer
Industry
Eligibility
18 Years and older
Enrollment
537 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
44
States / cities
Birmingham, Alabama • Mesa, Arizona • Little Rock, Arkansas + 39 more
Source: ClinicalTrials.gov public record
Updated Apr 22, 2012 · Synced Jun 7, 2026, 5:53 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Brain-based Understanding of Individual Language Differences After Stroke

NCT04991519
View directory record Official record
Conditions
Aphasia, Stroke, Alexia
Interventions
Not listed
Lead sponsor
Georgetown University
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2028
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Nov 11, 2024 · Synced Jun 7, 2026, 5:53 AM EDT
Completed Not applicable Interventional

Clinical Feasibility of Transcranial Direct Current Stimulation [tDCS] With Standard Aphasia Therapy

NCT03272906
View directory record Official record
Conditions
Aphasia, Stroke
Interventions
Anodal transcranial direct current stimulation, Sham transcranial direct current stimulation, Speech-language therapy
Device · Behavioral
Lead sponsor
Louisiana State University and A&M College
Other
Eligibility
18 Years to 85 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Mar 20, 2024 · Synced Jun 7, 2026, 5:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

STAMP: Sharing and Talking About My Preferences

NCT03137459
View directory record Official record
Conditions
Advanced Care Planning (ACP)
Interventions
Transtheoretical Model (TTM) of health behavior change, Usual Care
Behavioral · Other
Lead sponsor
Yale University
Other
Eligibility
55 Years and older
Enrollment
909 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 28, 2021 · Synced Jun 7, 2026, 5:53 AM EDT
Terminated Phase 4 Interventional Results available

Ketamine-assisted Therapy for Advanced GI Cancer

NCT06077487
View directory record Official record
Conditions
Pancreatic Ductal Adenocarcinoma, Pain, Acute, Gastrointestinal Cancers, Demoralization
Interventions
Ketamine, Ketamine Injectable Product, Meaning and Purpose therapy, Placebo, Questionnaires
Drug · Behavioral · Other
Lead sponsor
Brian Anderson, MD
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 20, 2025 · Synced Jun 7, 2026, 5:53 AM EDT
Enrolling by invitation Not applicable Interventional

Primary Progressive Aphasia Multicomponent Language Treatment Study

NCT06649084
View directory record Official record
Conditions
Primary Progressive Aphasia, Semantic Dementia, Semantic Memory Disorder, Logopenic Progressive Aphasia, Nonfluent Aphasia, Progressive, Aphasia, Aphasia, Progressive
Interventions
Multicomponent Lexical Retrieval Training (Multi-LRT), Multicomponent Video Implemented Script Training in Aphasia (Multi-VISTA), Multicomponent Communication Partner Training (Multi-CPT)
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
Not listed
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Oct 7, 2025 · Synced Jun 7, 2026, 5:53 AM EDT
Recruiting Not applicable Interventional

Producing Increasingly Complex Themes Using Right-hemisphere Engagement (PICTURE) Implemented With Telemedicine

NCT05845047
View directory record Official record
Conditions
Aphasia, Stroke
Interventions
PICTURE-IT, CoDeLT
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 99 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2031
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 22, 2025 · Synced Jun 7, 2026, 5:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Hearing Aid Labeling on Speech Understanding Measures

NCT05274178
View directory record Official record
Conditions
Hearing Loss
Interventions
Audeo P hearing aid labeled as "Prescriptive", Audeo P hearing aid labeled as "OTC"
Device
Lead sponsor
Sonova AG
Industry
Eligibility
18 Years to 95 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Aurora, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 9, 2023 · Synced Jun 7, 2026, 5:53 AM EDT
Completed Not applicable Interventional Results available

Talk Therapy by Phone to Promote Treatment for Alcohol Problems

NCT03758274
View directory record Official record
Conditions
Alcohol Use Disorder, Alcohol Abuse
Interventions
CBT by Phone to Promote Treatment, Reading the Subject a Pamphlet on Obtaining Alcohol Use Disorder Treatment
Behavioral · Other
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Oct 3, 2023 · Synced Jun 7, 2026, 5:53 AM EDT
Completed Not applicable Interventional Results available

Treatment Intensity - Apraxia of Speech

NCT02332915
View directory record Official record
Conditions
Aphasia, CVA, Apraxia of Speech
Interventions
Sound Production Treatment (SPT)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 90 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 11, 2022 · Synced Jun 7, 2026, 5:53 AM EDT
Completed Not applicable Interventional Results available

Apraxia of Speech: Comparison of EPG Treatment (Tx) and Sound Production Treatment (SPT)

NCT02554513
View directory record Official record
Conditions
Apraxia of Speech, Aphasia, Acquired, Speech Disorders
Interventions
EPG Tx, SPT
Device · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 80 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Nov 3, 2021 · Synced Jun 7, 2026, 5:53 AM EDT
Recruiting Not applicable Interventional

Rapid Non-Invasive Brain Stimulation for Hoarding Disorder

NCT06712914
View directory record Official record
Conditions
Hoarding Disorder, Hoarding, Clutter
Interventions
MagPro X100 by MagVenture
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Jun 7, 2026, 5:53 AM EDT
Enrolling by invitation Not applicable Interventional

taVNS for Speech and Language Recovery in Aphasia

NCT07563387
View directory record Official record
Conditions
Aphasia, Apraxia of Speech
Interventions
taVNS, sham taVNS
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 80 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated May 3, 2026 · Synced Jun 7, 2026, 5:53 AM EDT
Completed Not applicable Interventional

Self Care TALK Study - Promoting Stroke Caregiver Health

NCT00646217
View directory record Official record
Conditions
Caregiving
Interventions
Self Care Talk
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
55 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Nov 27, 2016 · Synced Jun 7, 2026, 5:53 AM EDT
Completed Not applicable Interventional

Modulating Intensity and Dosage of Aphasia Scripts

NCT04138940
View directory record Official record
Conditions
Aphasia
Interventions
Script Training
Behavioral
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
21 Years and older
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 27, 2025 · Synced Jun 7, 2026, 5:53 AM EDT