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Showing 1–24 of 347 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Speech and Language Disorder Clear all
Completed Not applicable Interventional Results available

Transmagnetic Stimulation Pilot in Primary Progressive Aphasia

NCT05860647
View directory record Official record
Conditions
Primary Progressive Aphasia
Interventions
Intermittent theta burst stimulation
Device
Lead sponsor
HealthPartners Institute
Other
Eligibility
40 Years to 90 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 2, 2025 · Synced Sep 7, 2026, 6:31 AM EDT
Completed Not applicable Interventional

Enhancing Reading Recovery in Aphasia With tDCS and Phonomotor Therapy

NCT06891638
View directory record Official record
Conditions
Stroke, Aphasia
Interventions
Schedule of tDCS administration
Device
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 80 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
West Orange, New Jersey • Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Sep 7, 2026, 6:31 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Speech Signals in Stuttering

NCT05668923
View directory record Official record
Conditions
Stuttering, Childhood
Interventions
Speech sound stimulation
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
5 Years to 17 Years
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
2
States / cities
Ann Arbor, Michigan • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Sep 7, 2026, 6:31 AM EDT
Completed Not applicable Interventional Results available

Assessing an Animal-Assisted Treatment Program for Adults With Aphasia: The Persons With Aphasia Training Dogs Program

NCT04610346
View directory record Official record
Conditions
Aphasia
Interventions
Persons with Aphasia Training Dogs Program
Behavioral
Lead sponsor
Albert Einstein Healthcare Network
Other
Eligibility
21 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Elkins Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 15, 2025 · Synced Sep 7, 2026, 6:31 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Transcranial Direct Current Stimulation (tDCS) and Cognitive Processing

NCT01602263
View directory record Official record
Conditions
Aphasia, Autism, Schizophrenia
Interventions
Transcranial Direct Current Stimulation (tDCS)
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 79 Years
Enrollment
307 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 6, 2023 · Synced Sep 7, 2026, 6:31 AM EDT
Completed No phase listed Observational

The Effect of Oral Candidiasis on the Speech Production, Feeding Skills, and Self-Concept of Children and Adolescents With Symptomatic HIV Infection

NCT00001448
View directory record Official record
Conditions
Candidiasis, Oral, Eating Disorders, HIV Infections, Speech Disorders
Interventions
Not listed
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
Not listed
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1995 – 2000
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Sep 7, 2026, 6:31 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Sentence Production Training in Aphasia

NCT05415501
View directory record Official record
Conditions
Aphasia
Interventions
Sentence training
Behavioral
Lead sponsor
Purdue University
Other
Eligibility
21 Years to 85 Years
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Dec 17, 2024 · Synced Sep 7, 2026, 6:31 AM EDT
Completed Phase 1 Interventional Results available

Assessment of Hyperphosphorylated Tau PET Binding in Primary Progressive Aphasia and Frontotemporal Dementia

NCT02736695
View directory record Official record
Conditions
Primary Progressive Aphasia, Behavioral Variant of Frontotemporal Dementia, Frontotemporal Dementia, Behavioral Variant
Interventions
F-18 AV 1451
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2024
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 20, 2025 · Synced Sep 7, 2026, 6:31 AM EDT
Recruiting Phase 4 Interventional

Longitudinal Multi-Modality Imaging in Progressive Apraxia of Speech

NCT01818661
View directory record Official record
Conditions
PPA, Non-fluent Aphasia, Apraxia of Speech, Primary Progressive Non-fluent Aphasia, Primary Progressive Aphasia
Interventions
AV-1451
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2028
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 11, 2025 · Synced Sep 7, 2026, 6:31 AM EDT
Terminated No phase listed Observational

Living With Aphasia: An International Study

NCT01234090
View directory record Official record
Conditions
Aphasia
Interventions
Not listed
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 14, 2016 · Synced Sep 7, 2026, 6:31 AM EDT
Completed Not applicable Interventional

Enhancing Written Communication in Persons With Aphasia

NCT01790880
View directory record Official record
Conditions
Aphasia, Stroke
Interventions
ORLA, ORLA + Writing
Behavioral
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 17, 2020 · Synced Sep 7, 2026, 6:31 AM EDT
Recruiting Phase 2 Interventional

Transcranial Magnetic Stimulation + Language Therapy to Treat Mild Aphasia

NCT06842745
View directory record Official record
Conditions
Aphasia, Stroke, Aphasia Following Cerebral Infarction, Aphasia, Acquired
Interventions
Transcranial Magnetic Stimulation (TMS), Speech-Language Therapy (SLT)
Device · Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
40 Years to 85 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Sep 7, 2026, 6:31 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Exercise Effects on Word Learning

NCT03370471
View directory record Official record
Conditions
Aging, Aphasia
Interventions
Retrieval Practice + Moderate Intensity Exercise, Retrieval Practice + Gentle Stretching, Study Only + Moderate Intensity Exercise, Study Only + Gentle Stretching
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
35 Years to 89 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 4, 2021 · Synced Sep 7, 2026, 6:31 AM EDT
Recruiting Not applicable Interventional

Promoting Early Intervention Timing and Attention to Language

NCT05853861
View directory record Official record
Conditions
MONITOR, COACH
Interventions
JASPER Babble
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
6 Months to 8 Months
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
2
States / cities
Los Angeles, California • Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Sep 7, 2026, 6:31 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Cochlear Implants in Young Children With SSD

NCT05775367
View directory record Official record
Conditions
Single Sided Deafness, Unilateral Deafness, Hearing Loss, Unilateral, Hearing Loss, Congenital Hearing Loss, Deafness One Ear
Interventions
Cochlear Implant
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
7 Months to 71 Months
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2030
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Sep 7, 2026, 6:31 AM EDT
Completed Not applicable Interventional

Speech Entrainment Treatment for People With Aphasia

NCT05687994
View directory record Official record
Conditions
Aphasia, Acquired
Interventions
Audiovisual Speech Entrainment Practice, Auditory Speech Entrainment Practice
Behavioral
Lead sponsor
Albert Einstein Healthcare Network
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Elkins Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 17, 2025 · Synced Sep 7, 2026, 6:31 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Transcranial Direct Current Stimulation (tDCS) With Verb Network Strengthening Treatment (VNeST) in Chronic Aphasia

NCT04142866
View directory record Official record
Conditions
Aphasia, Stroke
Interventions
Anodal transcranial direct current stimulation, Sham transcranial direct current stimulation, Speech-Language Therapy (SLT)
Device · Behavioral
Lead sponsor
City University of New York
Other
Eligibility
21 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 6, 2025 · Synced Sep 7, 2026, 6:31 AM EDT
Completed Not applicable Interventional

Intensive Dysarthria Sessions in Adults and Children With Down Syndrome

NCT01684670
View directory record Official record
Conditions
Dysarthria, Down Syndrome
Interventions
Speech sessions
Behavioral
Lead sponsor
Duke University
Other
Eligibility
8 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 22, 2016 · Synced Sep 7, 2026, 6:31 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Transcranial Alternating Current Stimulation (tACS) in Aphasia

NCT04375722
View directory record Official record
Conditions
Aphasia, Stroke
Interventions
tACS
Device
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 85 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2030
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Sep 7, 2026, 6:31 AM EDT
Recruiting Not applicable Interventional

Stuttering and Neuromodulation

NCT07222163
View directory record Official record
Conditions
Stuttering
Interventions
Soterix Medical 1x1 tDCS system, Speech therapy sessions
Device · Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Sep 7, 2026, 6:31 AM EDT
Recruiting Phase 2 Interventional

Comparing Traditional Semantic Feature Analysis (tSFA) and Semantic Feature Analysis + Metacognitive Strategy Training (SFA+MST)

NCT07036406
View directory record Official record
Conditions
Aphasia, Aphasia Following Cerebral Infarction, Aphasia, Acquired, Aphasia, Rehabilitation, Aphasia, Anomic, Aphasia, Broca, Aphasia, Conduction, Aphasia, Expressive, Aphasia Non Fluent, Aphasia, Mixed
Interventions
Semantic Feature Analysis (traditional), Semantic Feature Analysis + Metacognitive Strategy Training
Behavioral
Lead sponsor
Teachers College, Columbia University
Other
Eligibility
18 Years to 89 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Sep 7, 2026, 6:31 AM EDT
Recruiting Phase 2Phase 3 Interventional

Superiority Trial of Aphasia-focused Rehabilitation With tDCS Stimulation

NCT07688551
View directory record Official record
Conditions
Aphasia, Broca's Aphasia
Interventions
tDCS
Device
Lead sponsor
University of South Carolina
Other
Eligibility
25 Years to 80 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
3
States / cities
Charleston, South Carolina • Columbia, South Carolina • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Sep 7, 2026, 6:31 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

First Responder Aphasia Strategy Training

NCT06678854
View directory record Official record
Conditions
Aphasia
Interventions
Training about Aphasia
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Sep 7, 2026, 6:31 AM EDT
Recruiting Not applicable Interventional

Stimulating the Aging Brain Using Brain and Sensory Stimulation

NCT07650188
View directory record Official record
Conditions
Primary Progressive Aphasia
Interventions
tACS or multisensory stimulation
Device
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
45 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2035
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Sep 7, 2026, 6:31 AM EDT