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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Completed No phase listed Observational Results available

Impact of Sperm DNA Integrity on In Vitro Cycles

NCT01232465
Conditions
Male Infertility, Unexplained Infertility, Abortion, Habitual
Interventions
Not listed
Lead sponsor
Northwell Health
Other
Eligibility
Male only
Enrollment
420 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Manhasset, New York
Active, not recruiting Not applicable Interventional

HELIOS: Human Embryo Illumination to Enhance Development

NCT07311928
Conditions
IVF Outcomes
Interventions
Photobiomodulation
Other
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 48 Years · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
New York, New York
Conditions
Secondary Hypogonadism
Interventions
Androxal 12.5 mg/25 mg, Placebo Capsules, AndroGel 1.62%, Placebo Gel
Drug
Lead sponsor
Repros Therapeutics Inc.
Industry
Eligibility
18 Years to 60 Years · Male only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
9
States / cities
Birmingham, Alabama • Mobile, Alabama • Evanston, Illinois + 6 more
Conditions
Infertility, Female, Reproductive Techniques, Assisted, Fertilization in Vitro
Interventions
Intracytoplasmic Sperm Injection (ICSI), Conventional Insemination (IVF)
Procedure
Lead sponsor
Shady Grove Fertility Reproductive Science Center
Other
Eligibility
Female only
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Rockville, Maryland
Conditions
Male Infertility
Interventions
Andrositol® Test
Diagnostic Test
Lead sponsor
Lo.Li.Pharma s.r.l
Industry
Eligibility
18 Years to 50 Years · Male only
Enrollment
249 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Pasadena, California
Conditions
Infertility
Interventions
ICSI
Other
Lead sponsor
Reproductive Medicine Associates of New Jersey
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
7 participants
Timeline
2018 – 2021
U.S. locations
1
States / cities
Basking Ridge, New Jersey
Conditions
Inflammatory Bowel Disease (IBD)
Interventions
Semen & Data Collection
Procedure
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 40 Years · Male only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Madison, Wisconsin
Completed Not applicable Interventional Accepts healthy volunteers

FemaSeed LOCAL Artificial Insemination Trial

NCT04968847
Conditions
Infertility, Male Factor
Interventions
FemaSeed Localized Directional Insemination
Device
Lead sponsor
Femasys Inc.
Industry
Eligibility
19 Years to 40 Years · Female only
Enrollment
314 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
18
States / cities
Mobile, Alabama • Newark, Delaware • Clearwater, Florida + 13 more
Conditions
Secondary Hypogonadism
Interventions
enclomiphene citrate, Placebo
Drug
Lead sponsor
Repros Therapeutics Inc.
Industry
Eligibility
18 Years to 60 Years · Male only
Enrollment
181 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
13
States / cities
Mobile, Alabama • Little Rock, Arkansas • Rancho Cucamonga, California + 10 more
Conditions
DNA Damage, DNA Strand Breaks, Sperm DNA Fragmentation
Interventions
sperm separation device
Device
Lead sponsor
Richard Kordus, PhD, HCLD (ABB)
Other
Eligibility
18 Years to 34 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Greenville, South Carolina
Conditions
Observe Effect of Antioxidant on Sperm DNA Fragmention
Interventions
Natural Antioxidant supplement
Dietary Supplement
Lead sponsor
Colorado Center for Reproductive Medicine
Other
Eligibility
18 Years to 55 Years · Male only
Enrollment
54 participants
Timeline
2018 – 2022
U.S. locations
1
States / cities
Lone Tree, Colorado
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Project 1: Diet and Exercise Modulate the Sperm Epigenome in Men

NCT04175678
Conditions
Healthy Lifestyle, Obese, Men
Interventions
Diet, Exercise, Standard care
Other
Lead sponsor
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Other
Eligibility
18 Years to 40 Years · Male only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Torrance, California
Conditions
ART
Interventions
ZyMot Multi Sperm Separation Device (850 ul), Density Gradient Centrifugation
Device · Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
New York, New York
Conditions
Male Infertility, Testicular Diseases, Urologic and Male Genital Diseases, Lead Poisoning
Interventions
Not listed
Lead sponsor
National Institute of Environmental Health Sciences (NIEHS)
NIH
Eligibility
21 Years to 55 Years · Male only
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2007
U.S. locations
3
States / cities
Los Angeles, California • Manhasset, New York • Philadelphia, Pennsylvania
Conditions
Multiple Sclerosis, Sperm
Interventions
arbaclofen ER Tablets, Placebo for arbaclofen ER tablets
Drug
Lead sponsor
RVL Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 55 Years · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
2
States / cities
Miami, Florida • Tampa, Florida
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Evaluation Of Sperm Production With Healthy Male Volunteers Receiving Lyrica Or Placebo

NCT00631696
Conditions
Healthy
Interventions
Pregabalin, Placebo
Drug
Lead sponsor
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Industry
Eligibility
18 Years to 55 Years · Male only
Enrollment
222 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
13
States / cities
Mobile, Alabama • Phoenix, Arizona • Tarzana, California + 9 more
Conditions
Spermatozoa
Interventions
Fertilix, Placebo
Dietary Supplement · Other
Lead sponsor
University Reproductive Associates
Other
Eligibility
20 Years to 55 Years · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Hasbrouck Heights, New Jersey
Conditions
Infertility
Interventions
omega 3 fats, folic acid
Drug
Lead sponsor
Reproductive Partners Medical Group
Other
Eligibility
35 Years to 55 Years · Male only
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007
U.S. locations
1
States / cities
Redondo Beach, California
Conditions
Male Infertility, Low Sperm Quality, Low Testosterone, Low Energy, Low Libido
Interventions
WeNatal For Him Supplement
Dietary Supplement
Lead sponsor
WeNatal
Industry
Eligibility
30 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Las Vegas, Nevada
Withdrawn No phase listed Observational Accepts healthy volunteers

A Clinical Evaluation of Semen Quality Using the MiOXSYS™ System 2.0

NCT02839447
Conditions
Male Infertility
Interventions
Diagnostic
Diagnostic Test
Lead sponsor
Aytu BioPharma, Inc.
Industry
Eligibility
21 Years to 45 Years · Male only
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
6
States / cities
Miami, Florida • New Orleans, Louisiana • Rochester, Minnesota + 3 more
Completed No phase listed Observational Accepts healthy volunteers

Evaluation of New Semen Collection & Transportation Kit

NCT04536545
Conditions
Sperm Parameters in Fertile and Infertile Men
Interventions
Not listed
Lead sponsor
Turtle Health, Inc.
Industry
Eligibility
Male only
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Azoospermia, Nonobstructive, Infertility, Male
Interventions
Ultrasound-guided rete testis flushing and aspiration
Procedure
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older · Male only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Infertility
Interventions
SpermComet assay
Other
Lead sponsor
Bruce Shapiro M.D.
Industry
Eligibility
18 Years and older · Male only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Las Vegas, Nevada
Terminated Not applicable Interventional Results available

Effectiveness of Celecoxib After Surgical Sperm Retrieval

NCT01323595
Conditions
Pain
Interventions
Celecoxib, Sugar Pill
Drug
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
New York, New York