- Conditions
- Cold Induced Headache, Brain Freeze, Cold Induced Cephalgia, Headache
- Interventions
- Lidocaine Topical 4% Topical Solution, Bitrex, normal saline
- Drug
- Lead sponsor
- Wright State University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025
- U.S. locations
- 1
- States / cities
- Dayton, Ohio
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Showing 1–24
of 30
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Transformed Migraine, Chronic Daily Headache
- Interventions
- SPG Block with 5% Lidocaine gel, Amitriptyline
- Procedure · Drug
- Lead sponsor
- Rutgers, The State University of New Jersey
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2020
- U.S. locations
- 1
- States / cities
- New Brunswick, New Jersey
- Conditions
- Post-Dural Puncture Headache
- Interventions
- Lidocaine HCl Gel 2%, placebo gel
- Drug
- Lead sponsor
- University of Utah
- Other
- Eligibility
- 18 Years to 50 Years · Female only
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- Salt Lake City, Utah
- Conditions
- Sphenopalatine Ganglion Nerve Block
- Interventions
- Bupivacaine, angiocatheter
- Drug · Device
- Lead sponsor
- Montefiore Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 220 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- The Bronx, New York
- Conditions
- Headache, Stroke, Ischemic Stroke
- Interventions
- Liquid Lidocaine, Placebo
- Drug
- Lead sponsor
- University of Utah
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2025
- U.S. locations
- 1
- States / cities
- Salt Lake City, Utah
- Conditions
- Postdural Puncture Headache
- Interventions
- Epidural Blood Patch, Sphenopalatine Ganglion Block
- Device · Drug
- Lead sponsor
- Rutgers, The State University of New Jersey
- Other
- Eligibility
- 13 Years to 92 Years
- Enrollment
- 8 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2020
- U.S. locations
- 2
- States / cities
- New Brunswick, New Jersey
- Conditions
- Concussion, Headache
- Interventions
- Lidocaine in SphenoCath device, Saline Solution in SphenoCath device
- Combination Product
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 2 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- Ipsilateral Shoulder Pain
- Interventions
- Transnasal SPG block
- Procedure
- Lead sponsor
- NYU Langone Health
- Other
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 117 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2017
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Migraine in Children, Pain, Neuropathic
- Interventions
- Headache Journal, Sphenopalatine Block, Tx360
- Other · Drug · Device
- Lead sponsor
- Washington University School of Medicine
- Other
- Eligibility
- 8 Years to 17 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021
- U.S. locations
- 1
- States / cities
- St Louis, Missouri
- Conditions
- Headache
- Interventions
- Sphenopalatine ganglion Block, Epidural blood patch
- Drug · Procedure
- Lead sponsor
- University of Colorado, Denver
- Other
- Eligibility
- 18 Years to 45 Years · Female only
- Enrollment
- 4 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2018
- U.S. locations
- 1
- States / cities
- Aurora, Colorado
- Conditions
- Postdural Puncture Headache
- Interventions
- Sphenopalatine Ganglion Block, Placebo
- Procedure
- Lead sponsor
- University of Arkansas
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019
- U.S. locations
- 1
- States / cities
- Little Rock, Arkansas
- Conditions
- SAH (Subarachnoid Hemorrhage), Headache
- Interventions
- Transnasal sphenopalatine ganglion block
- Combination Product
- Lead sponsor
- University of California, Davis
- Other
- Eligibility
- 18 Years to 100 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Sacramento, California
- Conditions
- Headache, Migraine
- Interventions
- Tx360
- Device
- Lead sponsor
- Tian Medical Inc.
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 174 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2023
- U.S. locations
- 11
- States / cities
- New Haven, Connecticut • Stamford, Connecticut • Fort Gordon, Georgia + 8 more
- Conditions
- Aneurysmal Subarachnoid Hemorrhage (aSAH), Headache
- Interventions
- Lidocaine (drug), Tx 360
- Drug · Device
- Lead sponsor
- Wright State University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2027
- U.S. locations
- 1
- States / cities
- Dayton, Ohio
- Conditions
- Post Traumatic Stress Disorder
- Interventions
- Sphenopalatine ganglion block
- Other
- Lead sponsor
- New York State Psychiatric Institute
- Other
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 6 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2023
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Postdural Puncture Headache, Sphenopalatine Ganglion Block
- Interventions
- bupivacaine, placebo
- Drug
- Lead sponsor
- Wake Forest University Health Sciences
- Other
- Eligibility
- 18 Years to 45 Years · Female only
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2016
- U.S. locations
- 1
- States / cities
- Winston-Salem, North Carolina
- Conditions
- Trigeminal Neuralgia
- Interventions
- Nasal ganglion block for TN
- Device
- Lead sponsor
- Chicago Anesthesia Pain Specialists
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2017
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Chronic Migraine
- Interventions
- Marcaine, Saline
- Drug
- Lead sponsor
- Tian Medical Inc.
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 41 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2014
- U.S. locations
- 2
- States / cities
- Ann Arbor, Michigan • Springfield, Missouri
- Conditions
- Headache
- Interventions
- SPG Block, Standard IV Treatment
- Procedure · Drug
- Lead sponsor
- Kendall Healthcare Group, Ltd.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 84 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2021
- U.S. locations
- 1
- States / cities
- Miami, Florida
- Conditions
- Post-Dural Puncture Headache, Sphenopalatine Ganglion Block
- Interventions
- Lidocaine
- Drug
- Lead sponsor
- Milton S. Hershey Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 6 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2022
- U.S. locations
- 1
- States / cities
- Hershey, Pennsylvania
- Conditions
- Postdural Puncture Headache, Cerebrospinal Fluid Leak, Spinal; Puncture, Complications, Headache
- Interventions
- Lidocaine 4%, Placebo
- Drug
- Lead sponsor
- Washington University School of Medicine
- Other
- Eligibility
- 18 Years and older · Female only
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- St Louis, Missouri
- Conditions
- Migraine in Children, Sphenopalatine Neuralgia, Migraine in Adolescence
- Interventions
- Lidocaine topical, Prochlorperazine Injection
- Drug
- Lead sponsor
- Newark Beth Israel Medical Center
- Other
- Eligibility
- 10 Years to 20 Years
- Enrollment
- 72 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2022
- U.S. locations
- 1
- States / cities
- Newark, New Jersey
- Conditions
- Subarachnoid Hemorrhage, Headache
- Interventions
- Regional anesthetic SPG block-bilateral
- Drug
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 2 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2024
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Obesity
- Interventions
- 4% Lidocaine, Saline
- Drug · Other
- Lead sponsor
- NYU Langone Health
- Other
- Eligibility
- 18 Years to 70 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2017
- U.S. locations
- 1
- States / cities
- New York, New York