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ClinicalTrials.gov public records Last synced Oct 4, 2026, 5:17 AM EDT

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Showing 25–48 of 162 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Spinal Canal Stenosis Clear all
Completed No phase listed Observational Results available

Postmarket Registry for Evaluation of the Superion® Spacer

NCT04087811
View directory record Official record
Conditions
Lumbar Spinal Stenosis
Interventions
Superion® Indirect Decompression System (IDS)
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
45 Years and older
Enrollment
1,674 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
66
States / cities
Birmingham, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 60 more
Source: ClinicalTrials.gov public record
Updated Jul 6, 2023 · Synced Oct 4, 2026, 5:17 AM EDT
Recruiting Phase 1 Interventional

Novel Soluble Epoxide Hydrolase Inhibitor for Neuropathic Pain in Patients With Spinal Cord Injury

NCT06438471
View directory record Official record
Conditions
Spinal Cord Injuries, Neuropathic Pain, Degenerative Disc Disease, Spinal Stenosis, Spondylosis
Interventions
EC5026 oral tablet, Placebo oral tablet
Drug
Lead sponsor
EicOsis Human Health Inc.
Industry
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 10, 2026 · Synced Oct 4, 2026, 5:17 AM EDT
Withdrawn Phase 4 Interventional

Particulate vs. Nonparticulate Epidural Steroid Injections for Lumbar Foraminal Stenosis

NCT03245671
View directory record Official record
Conditions
Lumbar Spinal Stenosis
Interventions
Kenalog Injectable Product, Decadron Phosphate, Injectable, Epidural Steroid Injection
Drug · Procedure
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 6, 2017 · Synced Oct 4, 2026, 5:17 AM EDT
Completed Not applicable Interventional Results available

Making Better Lives: Patient-Focused Care for Low Back Pain (LBP)

NCT02697435
View directory record Official record
Conditions
Chronic Low Back Pain, Hip Ostearthritis, Myofascial Pain Syndrome, Fibromyalgia, Depression, Maladaptive Coping, Lumbar Spinal Stenosis, Insomnia, Sacroiliac Joint Pain, Lateral Hip and Thigh Pain, Anxiety, Dementia, Recent Leg Length Discrepancy
Interventions
Patient-Centered Care, Imaging-Directed Care
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
60 Years to 89 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 19, 2019 · Synced Oct 4, 2026, 5:17 AM EDT
Completed Phase 4 Interventional Results available

MiDAS II (Mild® Decompression Alternative to Open Surgery): Vertos Mild Patient Evaluation Study

NCT01082159
View directory record Official record
Conditions
Lumbar Spinal Stenosis
Interventions
lumbar decompression
Procedure
Lead sponsor
Vertos Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
8
States / cities
Merritt Island, Florida • Baltimore, Maryland • Festus, Missouri + 5 more
Source: ClinicalTrials.gov public record
Updated Apr 1, 2013 · Synced Oct 4, 2026, 5:17 AM EDT
Active, not recruiting Not applicable Interventional

A 5-year Superion™ IDS Clinical Outcomes Post-Approval Evaluation (SCOPE)

NCT04192591
View directory record Official record
Conditions
Lumbar Spinal Stenosis
Interventions
Superion™ IDS device
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
45 Years and older
Enrollment
166 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2041
U.S. locations
23
States / cities
Carlsbad, California • Larkspur, California • Rancho Mirage, California + 20 more
Source: ClinicalTrials.gov public record
Updated Sep 4, 2026 · Synced Oct 4, 2026, 5:17 AM EDT
Completed Phase 4 Interventional

Spine Patient Outcomes Research Trial (SPORT) - Intervertebral Disc Herniation

NCT00000410
View directory record Official record
Conditions
Herniated Disc, Low Back Pain
Interventions
Diskectomy, Non-surgical treatments
Procedure
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
501 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2015
U.S. locations
13
States / cities
Oakland, California • San Francisco, California • Decatur, Georgia + 9 more
Source: ClinicalTrials.gov public record
Updated Aug 4, 2015 · Synced Oct 4, 2026, 5:17 AM EDT
Recruiting Phase 4 Interventional

Regional Anesthesia in Minimally Invasive Lumbar Spine Surgery

NCT05029726
View directory record Official record
Conditions
Lumbar Spinal Stenosis, Lumbar Disc Herniation, Lumbar Spondylolisthesis, Lumbar Spondylosis, Lumbar Radiculopathy, Lumbar Spine Instability, Synovial Cyst, Degenerative Disc Disease, Degenerative Spondylolisthesis, Degenerative Intervertebral Discs
Interventions
Bupivacaine-Epinephrine 0.25%-1:200,000 Injectable Solution plus clonidine, normal saline
Drug
Lead sponsor
John O'Toole
Other
Eligibility
18 Years to 80 Years
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Oct 4, 2026, 5:17 AM EDT
Terminated Phase 3 Interventional Results available

DIAM™ Spinal Stabilization System vs. Decompression, Formerly vs. Posterolateral Fusion

NCT00627497
View directory record Official record
Conditions
Degenerative Lumbar Spinal Stenosis
Interventions
Single-Level Posterior Decompression, DIAM Spinal Stabilization, Fusion
Procedure · Device
Lead sponsor
Medtronic Spinal and Biologics
Industry
Eligibility
35 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
9
States / cities
Fremont, California • Jacksonville, Florida • Melbourne, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Jan 5, 2021 · Synced Oct 4, 2026, 5:17 AM EDT
Withdrawn Not applicable Interventional

Proprio Spine Measurement Tool

NCT07023393
View directory record Official record
Conditions
Intervertebral Disc Degeneration, Intervertebral Disc Displacement, Spinal Curvatures, Spinal Osteochondrosis, Spinal Osteophytosis, Spinal Stenosis, Spondylitis, Spondylosis
Interventions
Intraoperative spinal measurement system
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Oct 4, 2026, 5:17 AM EDT
Completed Early Phase 1 Interventional

Effectiveness of Caudal Epidural Injections in Treatment of Chronic Low Back and Lower Extremity Pain

NCT00370799
View directory record Official record
Conditions
Low Back Pain
Interventions
Caudal epidural injection, Caudal Epidural Injection with generic Celestone, Caudal Epidural Injection with Celestone, Caudal Epidural Injection with DepoMedrol
Drug
Lead sponsor
Pain Management Center of Paducah
Other
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Paducah, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 16, 2013 · Synced Oct 4, 2026, 5:17 AM EDT
Completed No phase listed Observational Results available

Long-Term Outcomes for Lumbar Spinal Stenosis Patients Treated With X STOP®

NCT00534092
View directory record Official record
Conditions
Lumbar Spinal Stenosis
Interventions
X STOP® Interspinous Process Decompression System
Device
Lead sponsor
Medtronic Spine LLC
Industry
Eligibility
50 Years and older
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
5
States / cities
San Francisco, California • Scarborough, Maine • Timonium, Maryland + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 5, 2021 · Synced Oct 4, 2026, 5:17 AM EDT
Completed Phase 4 Interventional

Spine Patient Outcomes Research Trial (SPORT): Degenerative Spondylolisthesis With Spinal Stenosis

NCT00000409
View directory record Official record
Conditions
Spondylolisthesis, Spinal Stenosis, Low Back Pain
Interventions
Decompressive laminectomy, Non-surgical treatments, Fusion--Instrumented, Fusion-Non-instrumented
Procedure · Other
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
304 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2015
U.S. locations
13
States / cities
Oakland, California • San Francisco, California • Decatur, Georgia + 9 more
Source: ClinicalTrials.gov public record
Updated Aug 4, 2015 · Synced Oct 4, 2026, 5:17 AM EDT
Not listed No phase listed Observational

Clinical and Radiographic Outcomes of TLIF w/3D Printed Cellular Implant

NCT05023733
View directory record Official record
Conditions
Foraminal Stenosis, Degenerative Disc Disease, Lumbar Spondylolisthesis, Lumbar Spinal Stenosis
Interventions
CONDUIT™ Interbody Platform composed of the EIT (Emerging Implant Technologies) Cellular Titanium®
Device
Lead sponsor
Farhan Karim
Other
Eligibility
35 Years to 80 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 28, 2022 · Synced Oct 4, 2026, 5:17 AM EDT
Withdrawn Not applicable Interventional

Focused Spinal Stenosis Rehabilitation Program for Lumbar Spinal Stenosis

NCT02982291
View directory record Official record
Conditions
Spinal Stenosis Lumbar
Interventions
Williams flexion protocol, Focused spinal stenosis rehabilitation
Procedure
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
40 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 5, 2018 · Synced Oct 4, 2026, 5:17 AM EDT
Completed Not applicable Interventional Results available

CEUS For Intraoperative Spinal Cord Injury

NCT05530798
View directory record Official record
Conditions
Spine Disease, Spinal Stenosis, Spinal Injury, Spinal Cord Diseases, Spinal Cord Injuries, Spinal Cord Compression, Spine Degeneration
Interventions
Definity Perflutren Lipid Microsphere Ultrasound Contrast
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 4, 2026 · Synced Oct 4, 2026, 5:17 AM EDT
Recruiting Phase 3 Interventional

Lumbar Steroid Use in Patients Undergoing Posterior Lumbar Decompression

NCT05058287
View directory record Official record
Conditions
Opioid Use, Lumbar Spinal Stenosis, Pain, Postoperative, Pain, Back
Interventions
Depo-Medrol 40Mg/Ml Suspension for Injection, Placebo
Drug
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 85 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Oct 4, 2026, 5:17 AM EDT
Withdrawn Not applicable Interventional

Comparison of the Order of Treatment in Lumbar Spinal Stenosis

NCT02103543
View directory record Official record
Conditions
Lumbar Spinal Stenosis
Interventions
physical therapy, lumbar interlaminar epidural steroid injection, epidural steroid injection
Other · Procedure · Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 23, 2017 · Synced Oct 4, 2026, 5:17 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

REFINE Study: A Study In a Novel Interspinous Fusion Device In Subjects With Low Back Pain

NCT05504499
View directory record Official record
Conditions
Lumbar Spinal Stenosis
Interventions
Interspinous Fusion
Device
Lead sponsor
Pacific Research Institute
Network
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2028
U.S. locations
10
States / cities
Santa Rosa, California • Jupiter, Florida • Slidell, Louisiana + 6 more
Source: ClinicalTrials.gov public record
Updated Aug 18, 2022 · Synced Oct 4, 2026, 5:17 AM EDT
Not listed No phase listed Observational

Retrospective, Multicenter Clinical Evaluation of Health Economic Drivers and Complications for Two Lumbar Fusion Procedures

NCT02171169
View directory record Official record
Conditions
Spinal Stenosis, Spondylolisthesis, Degenerative Disc Disease (DDD)
Interventions
Not listed
Lead sponsor
Baxano Surgical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
3
States / cities
Fullerton, California • Waterford, Michigan • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 3, 2014 · Synced Oct 4, 2026, 5:17 AM EDT
Terminated Not applicable Interventional Results available

Study Evaluating the Safety and Effectiveness of the FLEXUS(TM) Interspinous Spacer

NCT01156675
View directory record Official record
Conditions
Lumbar Spinal Stenosis
Interventions
FLEXUS(TM) Interspinous Spacer, XSTOP® Interspinous Spacer
Device
Lead sponsor
Globus Medical Inc
Industry
Eligibility
50 Years and older
Enrollment
215 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 1, 2018 · Synced Oct 4, 2026, 5:17 AM EDT
Completed Not applicable Interventional Results available

The MiDAS ENCORE Study

NCT02093520
View directory record Official record
Conditions
Spinal Stenosis, Lumbar Region, With Neurogenic Claudication
Interventions
MILD Procedure, Epidural Steroid Injection
Procedure · Drug
Lead sponsor
Vertos Medical, Inc.
Industry
Eligibility
65 Years and older
Enrollment
302 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
12
States / cities
Chula Vista, California • Fresno, California • Murrieta, California + 9 more
Source: ClinicalTrials.gov public record
Updated Dec 6, 2017 · Synced Oct 4, 2026, 5:17 AM EDT
Recruiting Not applicable Interventional

ESP Block in MIS Lumbar Spine Surgery

NCT05856539
View directory record Official record
Conditions
Patients With Spinal Stenosis Indicated for MIS TLIF
Interventions
Erector spinae plane (ESP) block
Procedure
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 80 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 6, 2025 · Synced Oct 4, 2026, 5:17 AM EDT
Recruiting No phase listed Observational

MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study

NCT03072927
View directory record Official record
Conditions
Lumbar Spinal Stenosis
Interventions
MILD, Interspinous Process Decompression
Device
Lead sponsor
Stryker Instruments
Industry
Eligibility
18 Years and older
Enrollment
8,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2026
U.S. locations
2382
States / cities
Athens, Alabama • Bay Minette, Alabama • Birmingham, Alabama + 1285 more
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 4, 2026, 5:17 AM EDT