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Showing 1–24 of 1,877 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Spinal Cord Disorders Clear all
Completed Not applicable Interventional

Subcutaneous Injection and Ultrasonic Dispersion of Cefazolin Into Chronic Pelvic-Region Pressure Ulcers in Persons With Spinal Cord Injury

NCT02584426
View directory record Official record
Conditions
Spinal Cord Injury, Chronic Pressure Ulcers
Interventions
Ultrasonic Distribution of Cefazolin
Device
Lead sponsor
James J. Peters Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 79 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Apr 24, 2022 · Synced Jun 27, 2026, 12:57 AM EDT
Not listed Phase 1Phase 2 Interventional

Timing and Dosage of Acute Intermittent Hypoxia in Persons With SCI

NCT03774043
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Acute Intermittent Hypoxia, Sham Acute Intermittent Hypoxia
Other
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 70 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 18, 2020 · Synced Jun 27, 2026, 12:57 AM EDT
Terminated Phase 2Phase 3 Interventional Results available

Study to Investigate the Safety and Efficacy of Lithium in Volunteers With Amyotrophic Lateral Sclerosis (ALS)

NCT00818389
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis
Interventions
Lithium Carbonate, Riluzole, placebo
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
22
States / cities
Phoenix, Arizona • Los Angeles, California • San Francisco, California + 19 more
Source: ClinicalTrials.gov public record
Updated Apr 18, 2011 · Synced Jun 27, 2026, 12:57 AM EDT
Not yet recruiting Not applicable Interventional

Resiliency Intervention for Patients With ALS and Their Care-Partners

NCT06968468
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis (ALS), Emotional Distress
Interventions
Resilient Together ALS
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 16, 2025 · Synced Jun 27, 2026, 12:57 AM EDT
Completed No phase listed Observational

Cardiac Disease and the Electrocardiogram in SCI Patients

NCT00013325
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Cardiac Disease
Procedure
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2002
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jan 20, 2009 · Synced Jun 27, 2026, 12:57 AM EDT
Recruiting Phase 1 Interventional

Safety and Feasibility of Intranasal Insulin in Patients With Spinal Cord Injury

NCT07384052
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Regular Insulin, 0.9 % Normal Saline
Drug · Other
Lead sponsor
HealthPartners Institute
Other
Eligibility
18 Years to 84 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 22, 2026 · Synced Jun 27, 2026, 12:57 AM EDT
Active, not recruiting Phase 2 Interventional Results available

A Study of Risdiplam in Infants With Genetically Diagnosed and Presymptomatic Spinal Muscular Atrophy

NCT03779334
View directory record Official record
Conditions
Muscular Atrophy, Spinal
Interventions
Risdiplam
Drug
Lead sponsor
Hoffmann-La Roche
Industry
Eligibility
1 Day to 6 Weeks
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Jun 27, 2026, 12:57 AM EDT
Terminated Not applicable Interventional

CREATION: A Clinical Trial of Qigong for Neuropathic Pain Relief in Adults With Spinal Cord Injury

NCT04917107
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Qigong
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 75 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 25, 2025 · Synced Jun 27, 2026, 12:57 AM EDT
Recruiting No phase listed Observational

Nerve Transfer to Improve Function in High Level Tetraplegia

NCT06288763
View directory record Official record
Conditions
Cervical Spinal Cord Injury, Tetraplegia
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
9
States / cities
Stanford, California • Miami, Florida • Baltimore, Maryland + 6 more
Source: ClinicalTrials.gov public record
Updated Mar 10, 2026 · Synced Jun 27, 2026, 12:57 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Modeling, Optimization, and Control Methods for a Personalized Hybrid Walking Exoskeleton

NCT04453943
View directory record Official record
Conditions
Spinal Cord Injuries, Paraplegia, Spinal, Paraplegia, Incomplete
Interventions
Exoskeleton Walking - with or without FES, Exoskeleton Sitting to Standing - with or without FES
Device
Lead sponsor
North Carolina State University
Other
Eligibility
18 Years to 60 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 30, 2020 · Synced Jun 27, 2026, 12:57 AM EDT
Completed Not applicable Interventional Results available

Mobility and Therapeutic Benefits Resulting From Exoskeleton Use in a Clinical Setting (SC140121 Study 1 and 2)

NCT03082898
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Indego Exoskeleton
Device
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
3
States / cities
Tampa, Florida • Rochester, Minnesota • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 15, 2022 · Synced Jun 27, 2026, 12:57 AM EDT
Terminated No phase listed Observational

A Multicenter Prospective Registry for the Management of Degenerative Spine Disorders

NCT02802033
View directory record Official record
Conditions
Degenerative Diseases, Spinal Cord
Interventions
Not listed
Lead sponsor
AO Innovation Translation Center
Other
Eligibility
18 Years and older
Enrollment
908 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2025
U.S. locations
5
States / cities
Los Angeles, California • Atlanta, Georgia • Baltimore, Maryland + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Jun 27, 2026, 12:57 AM EDT
Recruiting Not applicable Interventional

Seated Balance Using the Indego™

NCT04047992
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Indego™ Exoskeleton
Device
Lead sponsor
James J. Peters Veterans Affairs Medical Center
Federal
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated May 13, 2025 · Synced Jun 27, 2026, 12:57 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Brivaracetam to Reduce Neuropathic Pain in Chronic Spinal Cord Injury

NCT04379011
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Brivaracetam, Placebo
Drug · Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
2
States / cities
Englewood, Colorado • Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 13, 2025 · Synced Jun 27, 2026, 12:57 AM EDT
Recruiting Not applicable Interventional

Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Tablet-01)

NCT06511934
View directory record Official record
Conditions
Brainstem Stroke, ALS, Tetraplegia, Spinal Cord Injuries, Cervical Spinal Cord Injury
Interventions
BrainGate Neural Interface System
Device
Lead sponsor
Leigh R. Hochberg, MD, PhD.
Other
Eligibility
18 Years to 80 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Jun 27, 2026, 12:57 AM EDT
Completed No phase listed Observational

Spinal Cord Stimulation and Functional MRI

NCT01512121
View directory record Official record
Conditions
Complex Regional Pain Syndrome (CRPS), Neuropathic Leg Pain
Interventions
Not listed
Lead sponsor
Vibhor Krishna
Other
Eligibility
18 Years to 55 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 22, 2019 · Synced Jun 27, 2026, 12:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mechanisms of Arterial Hypotension in Chronic Spinal Cord Injury

NCT02154412
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Respiratory Training
Other
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2019
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 6, 2025 · Synced Jun 27, 2026, 12:57 AM EDT
Completed Not applicable Interventional

Caring for Caregivers: Supporting Caregivers of Youth With Spinal Cord Injury

NCT02083601
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Parent Forum, Psychological support
Behavioral
Lead sponsor
Erin Hayes Kelly, PhD
Other
Eligibility
7 Years and older
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 23, 2018 · Synced Jun 27, 2026, 12:57 AM EDT
Recruiting No phase listed Observational

The Myelin Disorders Biorepository Project

NCT03047369
View directory record Official record
Conditions
Leukodystrophy, White Matter Disease, Leukoencephalopathies, 4H Syndrome, Adrenoleukodystrophy, AMN, ALD, ALD Gene Mutation, ALD (Adrenoleukodystrophy), X-linked Adrenoleukodystrophy, X-ALD, Adrenomyeloneuropathy, Aicardi Goutieres Syndrome, AGS, Alexander Disease, Alexanders Leukodystrophy, AxD, ADLD, Canavan Disease, CTX, Cerebrotendinous Xanthomatoses, Krabbe Disease, GALC Deficiency, Globoid Leukodystrophy, TUBB4A-Related Leukodystrophy, H-ABC - Hypomyelination, Atrophy of Basal Ganglia and Cerebellum, HBSL, HBSL - Hypomyelination, Brain Stem, Spinal Cord, Leg Spasticity, LBSL, Leukoencephalopathy With Brain Stem and Spinal Cord Involvement and High Lactate Syndrome (Disorder), Leukoencephalopathy With Brainstem and Spinal Cord Involvement and Lactate Elevation, ALSP, CSF1R Gene Mutation, HCC - Hypomyelination and Congenital Cataract, MLC1, Megalencephalic Leukoencephalopathy With Subcortical Cysts, MLD, Metachromatic Leukodystrophy, PMD, Pelizaeus-Merzbacher Disease, PLP1 Null Syndrome, PLP1 Gene Duplication | Blood or Tissue | Mutations, Pelizaeus Merzbacher Like Disease, Peroxisomal Biogenesis Disorder, Zellweger Syndrome, Refsum Disease, Salla Disease, Sialic Storage Disease, Sjögren, Sjogren-Larsson Syndrome, Van Der Knapp Disease, Vanishing White Matter Disease, Charcot-Marie-Tooth, CMT, Mct8 (Slc16A2)-Specific Thyroid Hormone Cell Transporter Deficiency, Allan-Herndon-Dudley Syndrome, Cadasil, Cockayne Syndrome, Multiple Sulfatase Deficiency, Gangliosidoses, GM2 Gangliosidosis, BPAN, Labrune Syndrome, LCC, Mucopolysaccharidoses, TBCK-Related Intellectual Disability Syndrome
Interventions
Not listed
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
Not listed
Enrollment
12,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2030
U.S. locations
23
States / cities
Los Angeles, California • Orange, California • Palo Alto, California + 18 more
Source: ClinicalTrials.gov public record
Updated Oct 22, 2025 · Synced Jun 27, 2026, 12:57 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Biomechanics of Wheelchair Transfers

NCT00645567
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Unassisted Manual Transfer, Standard Transfer Board, Glide n' Go, Easy Reach lift, Ryno lift
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Apr 6, 2017 · Synced Jun 27, 2026, 12:57 AM EDT
Completed Not applicable Interventional

Upper Extremity Surgery in Spinal Cord Injury

NCT01899664
View directory record Official record
Conditions
Quadriplegia, Spinal Cord Diseases, Spinal Cord Injuries
Interventions
Nerve Transfer Surgery
Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 60 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2021
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 2, 2021 · Synced Jun 27, 2026, 12:57 AM EDT
Recruiting Phase 4 Interventional

Glycemic and Weight Loss Effects of GLP-1R Agonist Therapy in Subjects With Spinal Cord Injury and Type 2 Diabetes

NCT06706284
View directory record Official record
Conditions
Spinal Cord Injuries, Type 2 Diabetes
Interventions
Semaglutide Injectable Product, Placebo
Drug · Other
Lead sponsor
Marzieh Salehi
Other
Eligibility
18 Years to 70 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
2
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Jun 27, 2026, 12:57 AM EDT
Completed Phase 1 Interventional

A Dose Titration of Droxidopa in Patients With Spinal Cord Injury

NCT01354158
View directory record Official record
Conditions
Spinal Cord Injury, Hypotension
Interventions
Droxidopa
Drug
Lead sponsor
Bronx VA Medical Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jul 29, 2013 · Synced Jun 27, 2026, 12:57 AM EDT
Completed Not applicable Interventional

Enhanced Medical Rehabilitation for Spinal Cord Injury

NCT03952416
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Enhanced Medical Rehabilitation (EMR)
Behavioral
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 4, 2024 · Synced Jun 27, 2026, 12:57 AM EDT