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Showing 1–24 of 401 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Spinal Cord Injuries (SCI) Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cognitive-based Prosthetics to Improve Grasp and Reaching After SCI

NCT04577573
View directory record Official record
Conditions
Spinal Cord Injuries, Hand Weakness
Interventions
Cognition glove, Sensory brace
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Apr 24, 2025 · Synced Sep 22, 2026, 6:05 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Role of Enhancing Serotonin Receptors Activity for Sleep Apnea Treatment in Patients With SCI

NCT02458469
View directory record Official record
Conditions
Spinal Cord Injury, Sleep Disordered Breathing
Interventions
Buspirone, Trazodone, Placebo
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 13, 2021 · Synced Sep 22, 2026, 6:05 AM EDT
Completed Phase 2 Interventional Results available

Improving Ventilatory Capacity in Those With Chronic High Level SCI

NCT05041322
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Buspirone, Placebo
Drug
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 50 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 17, 2025 · Synced Sep 22, 2026, 6:05 AM EDT
Completed Not applicable Interventional Results available

Amplify Gait to Improve Locomotor Engagement in Spinal Cord Injury

NCT04340063
View directory record Official record
Conditions
Incomplete Spinal Cord Injury
Interventions
Gait training performed on a treadmill, Gait training performed in a Movement Amplification Environment
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 80 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Hines, Illinois
Source: ClinicalTrials.gov public record
Updated May 28, 2025 · Synced Sep 22, 2026, 6:05 AM EDT
Not listed Not applicable Interventional

Repetitive Transcranial Magnetic Stimulation to Promote Regeneration in Persons With SCI

NCT05333770
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
High-frequency repetitive transcranial magnetic stimulation
Device
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 55 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Oct 13, 2022 · Synced Sep 22, 2026, 6:05 AM EDT
Recruiting No phase listed Observational

Impact of Gut Microbiome on Metabolic and Bowel Function During the First Year After Spinal Cord Injury

NCT05670288
View directory record Official record
Conditions
Spinal Cord Injuries, Gut Microbiome
Interventions
Not listed
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 85 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Dec 16, 2025 · Synced Sep 22, 2026, 6:05 AM EDT
Active, not recruiting Not applicable Interventional

Telenutrition for Individuals With SCI

NCT05468437
View directory record Official record
Conditions
Spinal Cord Injuries, Obesity, Cardiometabolic Syndrome
Interventions
Telenutrition
Behavioral
Lead sponsor
Santa Clara Valley Health & Hospital System
Other
Eligibility
20 Years and older
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
San Jose, California
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Sep 22, 2026, 6:05 AM EDT
Recruiting Not applicable Interventional

Spinal Cord Injury Model Systems (SCIMS) - Education Module

NCT06003686
View directory record Official record
Conditions
Spinal Cord Injuries, Obesity, Cardiometabolic Syndrome
Interventions
PVA Consumer Guide, WebMD
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 70 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
3
States / cities
Washington D.C., District of Columbia • Miami, Florida • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Sep 22, 2026, 6:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Brain Plus Spinal Stimulation for Cervical SCI

NCT04727866
View directory record Official record
Conditions
Spinal Cord Injuries, Spinal Cord Injury at C5-C7 Level, Tetraplegia/Tetraparesis
Interventions
transcutaneous spinal direct current stimulation (tsDCS) - coronal, transcutaneous spinal direct current stimulation (tsDCS) - caudal, transcutaneous spinal direct current stimulation (tsDCS) - rostral, intermittent theta burst stimulation (iTBS)
Device
Lead sponsor
Bronx VA Medical Center
Federal
Eligibility
18 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jan 16, 2024 · Synced Sep 22, 2026, 6:05 AM EDT
Not listed Not applicable Interventional

Daily Intermittent Hypoxia and Task-Specific Upper Limb Training in Persons With Chronic Incomplete SCI

NCT03262766
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Acute Intermittent Hypoxia (AIH), Upper extremity training, Sham Acute intermittent hypoxia
Other · Behavioral
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 70 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 18, 2020 · Synced Sep 22, 2026, 6:05 AM EDT
Recruiting Not applicable Interventional

Precise Robotically IMplanted Brain-Computer InterfacE

NCT06429735
View directory record Official record
Conditions
Tetraplegia/Tetraparesis, Quadriplegia, Cervical Spinal Cord Injury, Amyotrophic Lateral Sclerosis, Quadriplegia/Tetraplegia, Tetraplegic; Paralysis
Interventions
N1 Implant, R1 Robot
Device
Lead sponsor
Neuralink Corp
Industry
Eligibility
22 Years to 75 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2031
U.S. locations
2
States / cities
Phoenix, Arizona • Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jan 8, 2026 · Synced Sep 22, 2026, 6:05 AM EDT
Terminated Early Phase 1 Interventional Accepts healthy volunteers

AIH for Spinal Cord Repair

NCT03780829
View directory record Official record
Conditions
SCI
Interventions
hypoxia, sham hypoxia, D-cycloserine, sham-NMDA agonist, exercise training
Behavioral · Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 85 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Hines, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Sep 22, 2026, 6:05 AM EDT
Completed Not applicable Interventional

Transspinal-Transcortical Paired Stimulation for Neuroplasticity and Recovery After SCI

NCT04624607
View directory record Official record
Conditions
Spinal Cord Injuries, Paraplegia, Spinal, Tetraplegia/Tetraparesis
Interventions
Transspinal-transcortical paired-associative stimiulation combined with robotic gait training, Transcortical-transspinal paired-associative stimiulation combined with robotic gait training
Device
Lead sponsor
College of Staten Island, the City University of New York
Other
Eligibility
18 Years to 70 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Staten Island, New York
Source: ClinicalTrials.gov public record
Updated Nov 12, 2020 · Synced Sep 22, 2026, 6:05 AM EDT
Enrolling by invitation Not applicable Interventional

Vagus Nerve Stimulation (VNS) in Spinal Cord Injury (SCI) Adaptive Follow-On Study

NCT06351111
View directory record Official record
Conditions
SCI - Spinal Cord Injury
Interventions
Active VNS
Device
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
18 Years to 64 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
2
States / cities
Dallas, Texas • Richardson, Texas
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Sep 22, 2026, 6:05 AM EDT
Completed Not applicable Interventional

Non-invasive Spinal Stimulation as an Adjuvant Therapy for Trunk Control After Pediatric SCI

NCT05091463
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Biostim-5/Neostim transcutaneous spinal stimulator
Device
Lead sponsor
University of Louisville
Other
Eligibility
3 Years to 12 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Sep 22, 2026, 6:05 AM EDT
Active, not recruiting Not applicable Interventional

AIH-induced Walking Recovery After Subacute SCI

NCT02632422
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Daily acute intermittent hypoxia (dAIH), dSHAM, Walking
Other
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2027
U.S. locations
2
States / cities
Atlanta, Georgia • Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Sep 22, 2026, 6:05 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Lower Limb Function After Spinal Cord Injury

NCT02635893
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
D-Cycloserine, Placebo, Training, Stimulation, Placebo Stimulation
Drug · Other
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 85 Years
Enrollment
257 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 30, 2021 · Synced Sep 22, 2026, 6:05 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Intermittent Hypoxia Elicits Prolonged Restoration of Motor Function in Human SCI

NCT01272349
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Acute intermittent hypoxia, Room air
Other
Lead sponsor
Emory University
Other
Eligibility
18 Years to 65 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
2
States / cities
Atlanta, Georgia • Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 20, 2013 · Synced Sep 22, 2026, 6:05 AM EDT
Not listed Phase 1 Interventional

Safety Study of Human Spinal Cord-derived Neural Stem Cell Transplantation for the Treatment of Chronic SCI

NCT01772810
View directory record Official record
Conditions
Spinal Cord Injury (SCI)
Interventions
Human spinal cord stem cells.
Drug
Lead sponsor
Neuralstem Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2022
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 10, 2017 · Synced Sep 22, 2026, 6:05 AM EDT
Completed Phase 1 Interventional

A Dose Titration of Droxidopa in Patients With Spinal Cord Injury

NCT01354158
View directory record Official record
Conditions
Spinal Cord Injury, Hypotension
Interventions
Droxidopa
Drug
Lead sponsor
Bronx VA Medical Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jul 29, 2013 · Synced Sep 22, 2026, 6:05 AM EDT
Completed Not applicable Interventional

FES Cycling and Nutritional Counseling for Battling Obesity After SCI

NCT03810963
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
HIIT-FES Cycling combined with Nutritional Counseling, Nutritional Counseling Only
Combination Product · Other
Lead sponsor
William Carey University
Other
Eligibility
21 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Hattiesburg, Mississippi
Source: ClinicalTrials.gov public record
Updated Oct 3, 2019 · Synced Sep 22, 2026, 6:05 AM EDT
Completed Not applicable Interventional Results available

Indego® Exoskeleton; Assessing Mobility for Persons With Spinal Cord Injury (SCI).

NCT02202538
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Indego
Device
Lead sponsor
Parker Hannifin Corporation
Industry
Eligibility
18 Years to 80 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
5
States / cities
Englewood, Colorado • Atlanta, Georgia • Chicago, Illinois + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 24, 2017 · Synced Sep 22, 2026, 6:05 AM EDT
Completed Not applicable Interventional

Physiological Changes Induced Through MEP Conditioning in People With SCI

NCT04286191
View directory record Official record
Conditions
Spinal Cord Injuries, Neurological Injury, Paralysis, Spasticity, Muscle
Interventions
Operant Conditioning, Control Group
Combination Product
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Dec 8, 2025 · Synced Sep 22, 2026, 6:05 AM EDT
Completed Not applicable Interventional

Connected Catheter (C2P) Study for Bladder Management

NCT03626324
View directory record Official record
Conditions
Urinary Retention, Neurogenic Bladder
Interventions
C2P
Device
Lead sponsor
Spinal Singularity
Industry
Eligibility
18 Years and older · Male only
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
8
States / cities
Peoria, Arizona • Surprise, Arizona • Downey, California + 5 more
Source: ClinicalTrials.gov public record
Updated Feb 7, 2019 · Synced Sep 22, 2026, 6:05 AM EDT