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ClinicalTrials.gov public records Last synced Nov 4, 2026, 1:50 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 337–360 of 420 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Spinal Deformities Clear all

Conditions: Incomplete Spinal Cord Injury, Muscular Dystrophy, Spina Bifida, Cerebral Palsy
Interventions: EA-KAFO; Device
Lead sponsor: National Institutes of Health Clinical Center (CC); NIH
Eligibility: 5 Years to 100 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2025
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Meningomyelocele, Spinal Dysraphism
Interventions: Prenatal Myelomeningocele Repair Surgery, Postnatal Myelomeningocele Repair Surgery; Procedure
Lead sponsor: The George Washington University Biostatistics Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 183 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003 – 2017
U.S. locations: 3
States / cities: San Francisco, California • Philadelphia, Pennsylvania • Nashville, Tennessee

Conditions: Spinal Fusion, Deformity of Spine
Interventions: iFuse Bedrock Granite Implant System; Device
Lead sponsor: SI-BONE, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 9
States / cities: Mobile, Alabama • Aurora, Colorado • Royal Oak, Michigan + 6 more

Conditions: Type 2 Spinal Muscular Atrophy
Interventions: OAV101, Sham control; Genetic · Procedure
Lead sponsor: Novartis Pharmaceuticals; Industry
Eligibility: 2 Years to 17 Years
Enrollment: 126 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 6
States / cities: Farmington, Connecticut • Chicago, Illinois • Strasburg, Pennsylvania + 2 more

Conditions: Spinocerebellar Ataxia Type 1, Spinocerebellar Ataxia 3
Interventions: Not listed
Lead sponsor: The Methodist Hospital Research Institute; Other
Eligibility: 18 Years to 65 Years
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2023
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Iron-sulfur Cluster Deficiency, Pulmonary Hypertension, Friedreich Ataxia
Interventions: Right Heart Catheterization, Blood draw; Procedure · Other
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years to 60 Years
Enrollment: 13 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2023
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Androgen Insensitivity Syndrome, Metabolic Parameters in AIS, CAIS, PAIS and MAIS, Tumor Formation in AIS, CAIS, PAIS and MAIS, Sexual Function AIS, CAIS, PAIS and MAIS
Interventions: Not listed
Lead sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); NIH
Eligibility: 8 Years to 99 Years
Enrollment: 650 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2040
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Spina Bifida
Interventions: Autologous umbilical cord patch; Procedure
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: Up to 24 Hours
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2033
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Lumbar Degenerative Disc Disease, Lumbar Spinal Stenosis, Lumbar Spondylolisthesis, Lumbar Spinal Deformity, Lumbar Spondylosis
Interventions: Interbody cage (titanium), Interbody cage (PEEK); Device
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older
Enrollment: 53 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Microsatellite Stable (MSS) Colorectal Adenocarcinomas, Colorectal Adenocarcinoma
Interventions: Nivolumab, Relatlimab; Drug
Lead sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins; Other
Eligibility: 18 Years and older
Enrollment: 59 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Cerebral Palsy, Spinal Muscular Atrophy, Spinal Cord Injuries, Spina Bifida, Development Delay, Genetic Disease
Interventions: Power Wheelchair Standing Device; Device
Lead sponsor: Grand Valley State University; Other
Eligibility: 5 Years to 17 Years
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2027
U.S. locations: 1
States / cities: Grand Rapids, Michigan

Conditions: Folate Deficiency, Neural Tube Defects
Interventions: Fortified Iodized Salt with Folic Acid (FISFA); Dietary Supplement
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 250 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Friedreich's Ataxia
Interventions: alpha-tocopherolquinone (A0001), placebo; Drug
Lead sponsor: Penwest Pharmaceuticals Co.; Industry
Eligibility: 18 Years to 60 Years
Enrollment: 42 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Scoliosis Idiopathic, Early-Onset Scoliosis Deformity of Spine
Interventions: Casting, Bracing; Procedure · Device
Lead sponsor: University of Iowa; Other
Eligibility: 12 Months to 36 Months
Enrollment: 71 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 24
States / cities: Little Rock, Arkansas • Aurora, Colorado • Wilmington, Delaware + 18 more

Conditions: Low Back Pain
Interventions: Intrathecal Morphine Injection, Pain Relieving; Drug
Lead sponsor: Sonoran Spine Research and Education Foundation; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 2
States / cities: Tempe, Arizona

Conditions: Hemangioblastoma, Hippel Lindau Disease
Interventions: Not listed
Lead sponsor: National Institute of Neurological Disorders and Stroke (NINDS); NIH
Eligibility: 8 Years to 75 Years
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2001
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Myelomeningocele, Pregnancy
Interventions: Open Fetal Repair of Myelomeningocele; Procedure
Lead sponsor: St. Louis University; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Fertility Issues
Interventions: Not listed
Lead sponsor: Bar-Chama, Natan, M.D.; Other
Eligibility: 18 Years to 50 Years · Male only
Enrollment: 75 participants
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Cresskill, New Jersey

Conditions: Juvenile and Adolescent Idiopathic Scoliosis
Interventions: differential rod bending with rod contours (MESA Spinal System); Procedure
Lead sponsor: Rush University Medical Center; Other
Eligibility: 10 Years to 18 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2022
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Fused Vertebrae, Ankylosing Spondylitis, Sagittal Deformities, Thoracolumbar Kyphosis
Interventions: Experimental: Montage Bone Hemostat; Device
Lead sponsor: Abyrx, Inc.; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Syracuse, New York

Conditions: Bacteriuria
Interventions: Lactobacillus reuteri RC-14 and Lactobacillus rhamnosus GR-1; Dietary Supplement
Lead sponsor: Baylor College of Medicine; Other
Eligibility: Up to 18 Years · Female only
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Friedreich Ataxia
Interventions: plethysmography; Diagnostic Test
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years to 79 Years
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Rheumatoid Arthritis (RA), Crohn's Disease (CD), Psoriatic Arthritis (PsA), Axial Spondyloarthritis and Ankylosing Spondylitis
Interventions: Not listed
Lead sponsor: UCB BIOSCIENCES, Inc.; Industry
Eligibility: 18 Years to 64 Years · Female only
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Wilmington, North Carolina

Conditions: Mucopolysaccharidosis I, Lysosomal Storage Diseases, Spinal Cord Compression
Interventions: laronidase; Drug
Lead sponsor: Patricia I. Dickson, M.D.; Individual
Eligibility: 8 Years and older
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2011
U.S. locations: 1
States / cities: Torrance, California

Search by objective public record fields.

Evaluating a New Knee-Ankle-Foot Brace to Improve Gait in Children With Movement Disorders

Management of Myelomeningocele Study (MOMS)

Pelvic Fixation and Fusion During Multilevel Spinal Surgery

Efficacy and Safety of Intrathecal OAV101 (AVXS-101) in Pediatric Patients With Type 2 Spinal Muscular Atrophy (SMA)

Clinical Trial Readiness for SCA1 and SCA3

Genetic and Environmental Determinants That Control Metabolism in Pulmonary Hypertension

Androgen Receptor, Implications for Health and Wellbeing: Natural History Study of Individuals With Androgen Insensitivity

Autologous Human Umbilical Cord Tissue Patch for Postnatal Closure of Open Neural Tube Defects

Lumbar Fusion With Nexxt Spine 3D-Printed Titanium Interbody Cages

Study of Nivolumab and Relatlimab in Patients With Microsatellite Stable (MSS) Advanced Colorectal Cancer

Pediatric Powered Wheelchair Standing Devices: An Exploratory Study

Folic Acid Salt Study (FISFA Zambia)

Safety and Efficacy Study of A0001 in Subjects With Friedreich's Ataxia

Casting vs Bracing for Idiopathic Early-Onset Scoliosis

Does Intrathecal Morphine Affect Outcomes in Spine Deformity Surgery

Study of Brain and Spinal Cord Tumor Growth and Cyst Development in Patients With Von Hippel Lindau Disease

Fetal Myelomeningocele Repair With Maternal BMI Between 35.0 and 40.0

Assessing the Fertility Status of Men With Spinal Muscular Atrophy (SMA)

3-D Correction of Adolescent Idiopathic Scoliosis (AIS) With Differential Metals

Clinical Investigation of MONTAGE in Adults With Spinal Deformity Undergoing Pedicle Subtraction Osteotomy

Bacteriuria Eradication Through Probiotics

Coronary Artery Disease in Patients With Friedreich's Ataxia

UCB Cimzia Pregnancy Follow-up Study

Intrathecal Enzyme Replacement Therapy for Spinal Cord Compression in Mucopolysaccharidosis (MPS) I