- Conditions
- Degenerative Disc Disease, Spondylolisthesis, Degenerative Scoliosis
- Interventions
- Not listed
- Lead sponsor
- NuVasive
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 109 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020
- U.S. locations
- 4
- States / cities
- Orange, California • Jacksonville, Florida • Charlotte, North Carolina
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Showing 25–48
of 24
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Degenerative Disc Disease, Degenerative Spondylolisthesis, Spinal Stenosis
- Interventions
- PLF with autograft, PLF with NeoFuse
- Procedure · Biological
- Lead sponsor
- Mesoblast, Ltd.
- Industry
- Eligibility
- 18 Years to 70 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2011
- U.S. locations
- 1
- States / cities
- Plano, Texas
- Conditions
- Solid Tumors
- Interventions
- thioureidobutyronitrile
- Drug
- Lead sponsor
- Cellceutix Corporation
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 48 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2016
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Degenerative Lumbar Spinal Stenosis, Degenerative Disc Disease, Degenerative Spondylolisthesis, Degenerative Disease
- Interventions
- Ropivacaine, Epinephrine, Clonidine, and Ketorolac Injection Cocktail, Placebo
- Drug · Other
- Lead sponsor
- University of Maryland, Baltimore
- Other
- Eligibility
- 18 Years to 88 Years
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Metastatic Colorectal Cancer
- Interventions
- Pembrolizumab, Binimetinib, Oxaliplatin, Leucovorin, 5-Fluorouracil [5-FU], Irinotecan
- Biological · Drug
- Lead sponsor
- Merck Sharp & Dohme LLC
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 116 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2023
- U.S. locations
- 10
- States / cities
- Duarte, California • Aurora, Colorado • New Haven, Connecticut + 7 more
- Conditions
- Lumbar Spondylolisthesis, Lumbar Spine Degeneration
- Interventions
- Not listed
- Lead sponsor
- Methodist Health System
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 3,500 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2028
- U.S. locations
- 1
- States / cities
- Dallas, Texas
- Conditions
- CACNA1A, Spinocerebellar Ataxia Type 6, Episodic Ataxia Type 2, Familial Hemiplegic Migraine-1
- Interventions
- N-Acetyl-L-Leucine, Placebo
- Drug · Other
- Lead sponsor
- IntraBio Inc
- Industry
- Eligibility
- 4 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 3
- States / cities
- Baltimore, Maryland • Boston, Massachusetts • Houston, Texas
- Conditions
- Friedreich Ataxia
- Interventions
- Respiratory Strength Training (RST)
- Other
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 1 participant
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Spinocerebellar Ataxia Type 3
- Interventions
- SLS-005, Placebo
- Drug
- Lead sponsor
- Seelos Therapeutics, Inc.
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 23 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2023
- U.S. locations
- 7
- States / cities
- Los Angeles, California • Aurora, Colorado • Tampa, Florida + 4 more
- Conditions
- Degenerative Disc Disease, Grade 1 Spondylolisthesis
- Interventions
- Spine fusion surgery with Clariance Idys TLIF 3DTi
- Device
- Lead sponsor
- Clariance
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 25 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2023
- U.S. locations
- 1
- States / cities
- College Station, Texas
- Conditions
- Degenerative Disc Disease
- Interventions
- Fortilink IBF System with TETRAfuse Technology
- Device
- Lead sponsor
- Xtant Medical
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 15 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2023
- U.S. locations
- 14
- States / cities
- Sherman Oaks, California • Lone Tree, Colorado • Boca Raton, Florida + 11 more
- Conditions
- Cervical Spondylosis, Cervical Radiculopathy, Cervical Degenerative Disc Disease
- Interventions
- DTRAX Graft
- Device
- Lead sponsor
- Providence Medical Technology, Inc.
- Industry
- Eligibility
- 35 Years to 80 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2015
- U.S. locations
- 2
- States / cities
- San Francisco, California
- Conditions
- Low Back Pain
- Interventions
- functional anesthetic discography, provocative discography
- Procedure
- Lead sponsor
- Medtronic Spine LLC
- Industry
- Eligibility
- 21 Years and older
- Enrollment
- 62 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2009
- U.S. locations
- 10
- States / cities
- Huntsville, Alabama • Beverly Hills, California • Escondido, California + 7 more
- Conditions
- Lumbar Disc Disease
- Interventions
- SIGNUS MOBIS PEEK Cage, SIGNUS MOBIS II ST Cage
- Device
- Lead sponsor
- Signus Medizintechnik GmbH
- Industry
- Eligibility
- 18 Years to 89 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2018
- U.S. locations
- 1
- States / cities
- East Syracuse, New York
- Conditions
- Spinal Curvatures
- Interventions
- Surgical intervention, None (Asymptomatic group)
- Procedure · Other
- Lead sponsor
- Texas Back Institute
- Other
- Eligibility
- 30 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2018
- U.S. locations
- 1
- States / cities
- Plano, Texas
- Conditions
- Degenerative Disc Disease
- Interventions
- Rexlemestrocel-L + HA mixture, Saline
- Drug
- Lead sponsor
- Mesoblast, Ltd.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 300 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2028
- U.S. locations
- 40
- States / cities
- Phoenix, Arizona • Tucson, Arizona • Chula Vista, California + 37 more
- Conditions
- Degenerative Disc Disease, Herniated Disc
- Interventions
- Use of conduit cages and fibergraft BG Putty
- Device
- Lead sponsor
- Nitin Agarwal
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2029
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Spondylolisthesis
- Interventions
- Not listed
- Lead sponsor
- Dartmouth-Hitchcock Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 171 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2021
- U.S. locations
- 1
- States / cities
- Lebanon, New Hampshire
- Conditions
- Lumbar Spondylolisthesis, Grade 1 Spondylolisthesis, Lumbar Spinal Stenosis, Degenerative Spondylolisthesis
- Interventions
- Expert Panel Review
- Other
- Lead sponsor
- Lahey Clinic
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 662 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2028
- U.S. locations
- 16
- States / cities
- Scottsdale, Arizona • San Francisco, California • Miami, Florida + 12 more
- Conditions
- Lumbar Degenerative Disc Disease
- Interventions
- Open PLIF (posterior lumbar interbody fusion), MAS PLIF
- Procedure
- Lead sponsor
- NuVasive
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 67 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2014
- U.S. locations
- 4
- States / cities
- Greensboro, North Carolina • York, Pennsylvania • Temple, Texas
- Conditions
- Degenerative Disc Disease
- Interventions
- Osteocel Plus
- Biological
- Lead sponsor
- NuVasive
- Industry
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 19 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2012
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Degenerative Disc Disease, Lumbar Fusion
- Interventions
- Adaptix nanoPEEK Cage, Capstone PTC Cage
- Device
- Lead sponsor
- Francis Farhadi
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 108 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Lexington, Kentucky
- Conditions
- Degenerative Conditions of the Lumbar Spine, Lumbar Spinal Stenosis, Spondylolisthesis
- Interventions
- Minuteman G5 Device
- Device
- Lead sponsor
- Spinal Simplicity LLC
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2030
- U.S. locations
- 6
- States / cities
- Newnan, Georgia • Indianapolis, Indiana • Kansas City, Kansas + 3 more
- Conditions
- Degenerative Disc Disease, Spine Fusion, Leg Pain and/or Back Pain
- Interventions
- MagnetOs Flex Matrix, Trinity Elite
- Device
- Lead sponsor
- Kuros Biosurgery AG
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 8
- States / cities
- Hartford, Connecticut • Chicago, Illinois • Columbia, Maryland + 5 more