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ClinicalTrials.gov public records Last synced Oct 21, 2026, 12:45 AM EDT

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Showing 73–96 of 322 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Spinal Fusion Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

REFINE Study: A Study In a Novel Interspinous Fusion Device In Subjects With Low Back Pain

NCT05504499
View directory record Official record
Conditions
Lumbar Spinal Stenosis
Interventions
Interspinous Fusion
Device
Lead sponsor
Pacific Research Institute
Network
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2028
U.S. locations
10
States / cities
Santa Rosa, California • Jupiter, Florida • Slidell, Louisiana + 6 more
Source: ClinicalTrials.gov public record
Updated Aug 18, 2022 · Synced Oct 21, 2026, 12:45 AM EDT
Terminated Phase 3 Interventional Results available

Evaluating the Role of Pregabalin in Reducing Opioid Requirement in Spinal Fusion Surgeries of Two or More Vertebrae

NCT03031340
View directory record Official record
Conditions
Spinal Fusion
Interventions
Pregabalin, placebo
Drug · Other
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Aug 20, 2019 · Synced Oct 21, 2026, 12:45 AM EDT
Not listed Phase 2 Interventional

KUR-113 Bone Graft Versus Local Autograft for the Treatment of Single-level Transforaminal Lumbar Interbody Fusion

NCT04294004
View directory record Official record
Conditions
Degenerative Disc Disease, Spinal Fusion
Interventions
TGplPTH1-34 in fibrin, Autologous Bone Graft
Combination Product · Other
Lead sponsor
Kuros Biosurgery AG
Industry
Eligibility
25 Years to 75 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
15
States / cities
La Jolla, California • Boulder, Colorado • Washington D.C., District of Columbia + 11 more
Source: ClinicalTrials.gov public record
Updated Aug 9, 2023 · Synced Oct 21, 2026, 12:45 AM EDT
Completed Not applicable Interventional

Comparison of nanOss Bioactive With Autograft and Bone Marrow Aspirate to Autograft in the Posterolateral Spine

NCT01968993
View directory record Official record
Conditions
Degenerative Disc Disease, Spinal Stenosis, Spondylolisthesis
Interventions
nanOss Bioactive - posterolateral gutter
Device
Lead sponsor
Pioneer Surgical Technology, Inc.
Industry
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
3
States / cities
La Jolla, California • San Francisco, California • Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 8, 2016 · Synced Oct 21, 2026, 12:45 AM EDT
Terminated Not applicable Interventional

Collar Immobilization Following a Posterior Cervical Laminectomy and Fusion

NCT01383876
View directory record Official record
Conditions
Cervical Spondylosis Symptomatic Neurological Compression
Interventions
Collar, No Collar
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 22, 2013 · Synced Oct 21, 2026, 12:45 AM EDT
Not yet recruiting No phase listed Observational

Assessing Safety of Cervical Spine Fusion With NMP®

NCT07245940
View directory record Official record
Conditions
Degenerative Disc Disease, Degenerative Spondylolisthesis, Spinal Stenosis Cervical
Interventions
Natural Matrix Protein (NMP) Fibers, Cervical interbody fusion
Biological · Procedure
Lead sponsor
Red Rock Regeneration Inc.
Industry
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Jasper, Alabama
Source: ClinicalTrials.gov public record
Updated Nov 24, 2025 · Synced Oct 21, 2026, 12:45 AM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Ketorolac Effects on Post-operative Pain and Lumbar Fusion

NCT06513208
View directory record Official record
Conditions
Lumbar Spinal Fusion
Interventions
Ketorolac Tromethamine, Placebo
Drug
Lead sponsor
University of Maryland St. Joseph Medical Center
Other
Eligibility
18 Years to 85 Years
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Towson, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 22, 2025 · Synced Oct 21, 2026, 12:45 AM EDT
Enrolling by invitation No phase listed Observational

Advanced Materials Science in XLIF Study

NCT03649490
View directory record Official record
Conditions
Degenerative Disc Disease, Spondylolisthesis
Interventions
Not listed
Lead sponsor
NuVasive
Industry
Eligibility
18 Years to 80 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
15
States / cities
Hartford, Connecticut • Jacksonville, Florida • Tampa, Florida + 12 more
Source: ClinicalTrials.gov public record
Updated Dec 22, 2025 · Synced Oct 21, 2026, 12:45 AM EDT
Completed No phase listed Observational

Pharmacokinetics of Aminocaproic Acid in Scoliosis Surgery

NCT01408823
View directory record Official record
Conditions
Scoliosis
Interventions
Not listed
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
8 Years to 18 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 9, 2013 · Synced Oct 21, 2026, 12:45 AM EDT
Enrolling by invitation Not applicable Interventional

Assessing Microbiome in Primary Anterior Cervical Fusion Patients

NCT07877766
View directory record Official record
Conditions
Cervical Stenosis, Myelopathy, Cervical Spondylosis With Myelopathy, Degenerative Disc Disease, Radiculopathy
Interventions
Primary Anterior Cervical Discectomy Procedures
Procedure
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 80 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 16, 2026 · Synced Oct 21, 2026, 12:45 AM EDT
Terminated No phase listed Observational

Aspen Spinous Process Fixation System for Use in PLF in Patients With Spondylolisthesis

NCT01560273
View directory record Official record
Conditions
Spondylolisthesis
Interventions
Aspen Spinous Process Fixation Device
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
50 Years to 80 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
5
States / cities
Phoenix, Arizona • Mission Viejo, California • Indianapolis, Indiana + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 9, 2019 · Synced Oct 21, 2026, 12:45 AM EDT
Not listed No phase listed Observational

Prospective Study of Safety and Efficacy of InQu® Bone Graft Extender in Lumbar Interbody Fusion Surgery

NCT02400762
View directory record Official record
Conditions
Intervertebral Disc Degeneration
Interventions
Not listed
Lead sponsor
ISTO Technologies, Inc.
Industry
Eligibility
18 Years and older
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
2
States / cities
Los Angeles, California • Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 31, 2017 · Synced Oct 21, 2026, 12:45 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Changes in Cerebral Oxygenation During the Administration of Cell Saver Blood and Allogeneic Blood

NCT02607150
View directory record Official record
Conditions
Idiopathic Scoliosis, Transfusion Reaction
Interventions
Cerebral Oxygenation Changes
Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
Not listed
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 7, 2016 · Synced Oct 21, 2026, 12:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Prospective, Multi-center Study to Assess Posterolateral Fusion Using FIBERGRAFT

NCT03884283
View directory record Official record
Conditions
Degenerative Disc Disease, Spondylolisthesis, Spinal Stenosis Lumbar
Interventions
FIBERGRAFT BG Matrix
Device
Lead sponsor
Prosidyan, Inc.
Industry
Eligibility
18 Years and older
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
9
States / cities
Long Beach, California • Wellington, Florida • Paducah, Kentucky + 5 more
Source: ClinicalTrials.gov public record
Updated Apr 22, 2024 · Synced Oct 21, 2026, 12:45 AM EDT
Terminated Phase 3 Interventional Results available

Efficacy and Safety of Tranexamic Acid in Spinal Fusion Surgery

NCT03425799
View directory record Official record
Conditions
Spinal Fusion
Interventions
Sodium Chloride 0.9% Inj, Tranexamic Acid
Drug
Lead sponsor
Exela Pharma Sciences, LLC.
Industry
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
4
States / cities
Long Beach, California • Los Angeles, California • Chicago, Illinois + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 21, 2021 · Synced Oct 21, 2026, 12:45 AM EDT
Terminated No phase listed Observational

A Multicenter Prospective Registry for the Management of Degenerative Spine Disorders

NCT02802033
View directory record Official record
Conditions
Degenerative Diseases, Spinal Cord
Interventions
Not listed
Lead sponsor
AO Innovation Translation Center
Other
Eligibility
18 Years and older
Enrollment
908 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2025
U.S. locations
5
States / cities
Los Angeles, California • Atlanta, Georgia • Baltimore, Maryland + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 21, 2026, 12:45 AM EDT
Completed Phase 4 Interventional Results available

Intrathecal Morphine Versus Epidural Extended Release Morphine for Pediatric Patients Undergoing Spinal Fusion

NCT00880607
View directory record Official record
Conditions
Pain Management, Spinal Fusion, Scoliosis
Interventions
Intrathecal morphine, Extended Release Epidural Morphine
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
8 Years to 17 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 22, 2020 · Synced Oct 21, 2026, 12:45 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Kids With Iron Deficiency and Scoliosis

NCT06042699
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis, Neuromuscular Scoliosis, Perioperative/Postoperative Complications, Iron Deficiencies, Anemia, Spinal Fusion, Postoperative Cognitive Dysfunction
Interventions
Oral ferrous sulfate, Oral placebo tablet
Dietary Supplement
Lead sponsor
Columbia University
Other
Eligibility
10 Years to 26 Years
Enrollment
275 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 26, 2026 · Synced Oct 21, 2026, 12:45 AM EDT
Not listed No phase listed Observational

Retrospective, Multicenter Clinical Evaluation of Health Economic Drivers and Complications for Two Lumbar Fusion Procedures

NCT02171169
View directory record Official record
Conditions
Spinal Stenosis, Spondylolisthesis, Degenerative Disc Disease (DDD)
Interventions
Not listed
Lead sponsor
Baxano Surgical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
3
States / cities
Fullerton, California • Waterford, Michigan • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 3, 2014 · Synced Oct 21, 2026, 12:45 AM EDT
Enrolling by invitation No phase listed Observational

Perioperative Sleep Quality and Postoperative Pain Outcomes

NCT06054802
View directory record Official record
Conditions
Surgery, Pain, Sleep, Spinal Fusion
Interventions
eCAP
Device
Lead sponsor
Grant Heydinger
Other
Eligibility
10 Years to 18 Years
Enrollment
166 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Oct 21, 2026, 12:45 AM EDT
Completed Not applicable Interventional

Interbody Spacers With map3® Cellular Allogeneic Bone Graft in Anterior or Lateral Lumbar Interbody Fusion

NCT02628210
View directory record Official record
Conditions
Spondylosis, Spondylolisthesis, Degenerative Disc Disease
Interventions
map3® Cellular Allogeneic Bone Graft
Other
Lead sponsor
RTI Surgical
Industry
Eligibility
18 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
3
States / cities
Niagara Falls, New York • Williamsville, New York • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated May 24, 2021 · Synced Oct 21, 2026, 12:45 AM EDT
Terminated No phase listed Observational

Bone Graft Materials Observational Registry

NCT00974623
View directory record Official record
Conditions
Degenerative Disc Disease, Herniated Disc, Spinal Stenosis, Spondylolithesis, Spinal Deformity, Cervical Myelopathy, Failed Back Surgery Syndrome, Spinal Cord Neoplasms
Interventions
Bone graft substitute, autograft or allograft
Device
Lead sponsor
Baxter Healthcare Corporation
Industry
Eligibility
18 Years and older
Enrollment
329 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
12
States / cities
San Francisco, California • Atlanta, Georgia • Carrollton, Georgia + 9 more
Source: ClinicalTrials.gov public record
Updated Apr 5, 2017 · Synced Oct 21, 2026, 12:45 AM EDT
Completed No phase listed Observational

PEEK and Allograft Spacers Evaluation in Spinal Fusion Surgeries

NCT01406405
View directory record Official record
Conditions
Degenerative Disc Disease
Interventions
Posterior/Transforaminal Lumbar Interbody Fusion (P/TLIF), Anterior Cervical Discectomy and Fusion (ACDF)
Procedure
Lead sponsor
Justin Parker Neurological Institute
Other
Eligibility
18 Years to 70 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2018
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 27, 2019 · Synced Oct 21, 2026, 12:45 AM EDT
Completed Phase 2 Interventional

Safety and Preliminary Efficacy Study of NeoFuse in Subjects Undergoing Multi-Level Anterior Cervical Discectomy

NCT01097486
View directory record Official record
Conditions
Cervical Degenerative Disc Disease, Degenerative Spondylolisthesis, Spinal Stenosis
Interventions
NeoFuse, Allograft
Biological · Procedure
Lead sponsor
Mesoblast, Ltd.
Industry
Eligibility
18 Years to 70 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
8
States / cities
Sacramento, California • Santa Monica, California • Denver, Colorado + 5 more
Source: ClinicalTrials.gov public record
Updated Aug 16, 2019 · Synced Oct 21, 2026, 12:45 AM EDT