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ClinicalTrials.gov public records Last synced Jun 11, 2026, 3:53 AM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Spinal Fusion Failure Clear all
Completed Not applicable Interventional

A Randomized Exercise Trial for Wheelchair Users

NCT00866112
View directory record Official record
Conditions
Spinal Cord Injury, Multiple Sclerosis, Muscular Dystrophy, Cerebral Palsy, Spina Bifida, Amputation, Arthritis, Stroke
Interventions
Educational session to promote physical activity, Minimal contact
Other
Lead sponsor
University of Kansas
Other
Eligibility
18 Years to 65 Years
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Lawrence, Kansas
Source: ClinicalTrials.gov public record
Updated Jun 14, 2012 · Synced Jun 11, 2026, 3:53 AM EDT
Recruiting Not applicable Interventional

Transcutaneous Spinal Stimulation for Children and Youth With Spina Bifida

NCT06918119
View directory record Official record
Conditions
Myelomeningocele, Spina Bifida
Interventions
Transcutaneous stimulation
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
5 Years to 18 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 13, 2025 · Synced Jun 11, 2026, 3:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Management of Myelomeningocele Study (MOMS)

NCT00060606
View directory record Official record
Conditions
Meningomyelocele, Spinal Dysraphism
Interventions
Prenatal Myelomeningocele Repair Surgery, Postnatal Myelomeningocele Repair Surgery
Procedure
Lead sponsor
The George Washington University Biostatistics Center
Other
Eligibility
18 Years and older · Female only
Enrollment
183 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2017
U.S. locations
3
States / cities
San Francisco, California • Philadelphia, Pennsylvania • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 6, 2020 · Synced Jun 11, 2026, 3:53 AM EDT
Recruiting Not applicable Interventional

Laparotomy Versus Percutaneous Endoscopic Correction of Myelomeningocele

NCT03856034
View directory record Official record
Conditions
Neural Tube Defects, Spina Bifida, Myelomeningocele, Chiari Malformation
Interventions
Fetoscopy
Device
Lead sponsor
USFetus
Other
Eligibility
18 Years and older · Female only
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2027
U.S. locations
2
States / cities
Los Angeles, California • Wellington, Florida
Source: ClinicalTrials.gov public record
Updated Nov 12, 2019 · Synced Jun 11, 2026, 3:53 AM EDT
Recruiting Not applicable Interventional

Evaluating Long-term Use of a Pediatric Robotic Exoskeleton (P.REX/Agilik) to Improve Gait in Children With Movement Disorders

NCT05726591
View directory record Official record
Conditions
Cerebral Palsy, Muscular Dystrophy, Spina Bifida, Incomplete Spinal Cord Injury
Interventions
EA-KAFO
Device
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
3 Years to 17 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 26, 2025 · Synced Jun 11, 2026, 3:53 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

In-Utero Endoscopic Correction of Spina Bifida

NCT04362592
View directory record Official record
Conditions
Neural Tube Defects, Spina Bifida, Myelomeningocele
Interventions
In Utero Endoscopic Correction of Myelomeningocele IDE - Percutaneous Technique, In Utero Endoscopic Correction of Myelomeningocele IDE - Laparotomy/Uterine Exteriorization Technique
Device
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 52 Years · Female only
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2031
U.S. locations
2
States / cities
Los Angeles, California • Wellington, Florida
Source: ClinicalTrials.gov public record
Updated May 3, 2026 · Synced Jun 11, 2026, 3:53 AM EDT
Terminated Not applicable Interventional

Fetal Myelomeningocele Repair With Maternal BMI Between 35.0 and 40.0

NCT02509377
View directory record Official record
Conditions
Myelomeningocele, Pregnancy
Interventions
Open Fetal Repair of Myelomeningocele
Procedure
Lead sponsor
St. Louis University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 27, 2018 · Synced Jun 11, 2026, 3:53 AM EDT
Recruiting Not applicable Interventional

tSCS in Children With Spina Bifida

NCT07615686
View directory record Official record
Conditions
Spina Bifida, Myelomeningocele
Interventions
Transcutaneous stimulator
Device
Lead sponsor
Bailey Petersen
Other
Eligibility
4 Years to 17 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Jun 11, 2026, 3:53 AM EDT
Completed Not applicable Interventional

Evaluating a New Knee-Ankle-Foot Brace to Improve Gait in Children With Movement Disorders

NCT01961557
View directory record Official record
Conditions
Incomplete Spinal Cord Injury, Muscular Dystrophy, Spina Bifida, Cerebral Palsy
Interventions
EA-KAFO
Device
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
5 Years to 100 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2025
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Jun 11, 2026, 3:53 AM EDT
Terminated Not applicable Interventional Results available

Yulex Glove Prospective Study in Spina Bifida

NCT01133288
View directory record Official record
Conditions
Spina Bifida, Latex Allergy
Interventions
Yulex gloves
Device
Lead sponsor
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Other
Eligibility
18 Years to 60 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 22, 2011 · Synced Jun 11, 2026, 3:53 AM EDT
Completed Not applicable Interventional Results available

Hemangioma Associated With High Rates of Morbidity

NCT00394888
View directory record Official record
Conditions
Hemangioma
Interventions
MRI, MRI of head and neck, Dermatological Examination, Cardiac examination, Abdominal ultrasound
Device · Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
Up to 18 Years
Enrollment
433 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 19, 2013 · Synced Jun 11, 2026, 3:53 AM EDT
Completed Phase 1 Interventional

Fetoscopic Meningomyelocele Repair Study

NCT02230072
View directory record Official record
Conditions
Neural Tube Defect
Interventions
fetoscopy
Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 64 Years · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2025
U.S. locations
2
States / cities
Stanford, California • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 9, 2025 · Synced Jun 11, 2026, 3:53 AM EDT
Recruiting Not applicable Interventional

Investigation of Surgical Sectioning of the Filum Terminale in Treating Occult Tethered Cord Syndrome Patients

NCT05163899
View directory record Official record
Conditions
Tethered Cord, Tethered Cord Syndrome, Occult Spina Bifida, Spina Bifida Occulta
Interventions
Release of filum terminale
Procedure
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
2 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Jun 11, 2026, 3:53 AM EDT
Recruiting No phase listed Observational

Bowel Continence Across the Lifespan in People With Spina Bifida

NCT07390318
View directory record Official record
Conditions
Spina Bifida, Neurogenic Bowel, Bowel Incontinence
Interventions
Retrograde Enema, Antegrade Enema
Procedure
Lead sponsor
David Chu
Other
Eligibility
5 Years and older
Enrollment
943 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
24
States / cities
Birmingham, Alabama • Phoenix, Arizona • Los Angeles, California + 18 more
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Jun 11, 2026, 3:53 AM EDT
Completed Not applicable Interventional

A New Training to Enhance Physical Activity in Adolescents With Cerebral Palsy

NCT05865418
View directory record Official record
Conditions
Cerebral Palsy, Muscle Disorder, Physical Disability, Posture Disorders in Children, Spina Bifida
Interventions
Loaded high intensity training, High intensity circuit training (HICT)
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
11 Years to 21 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 24, 2025 · Synced Jun 11, 2026, 3:53 AM EDT
Completed Not applicable Interventional

Telemedicine in Spina Bifida Transition: A Pilot Study

NCT03466996
View directory record Official record
Conditions
Spina Bifida
Interventions
Intervention group, Standard of care group
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
13 Years to 25 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 19, 2021 · Synced Jun 11, 2026, 3:53 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Salt-FA to Increase Folate Levels

NCT06174883
View directory record Official record
Conditions
Neural Tube Defects, Folic Acid Deficiency, Spina Bifida, Anencephaly-Spina Bifida
Interventions
Folic acid fortified iodized salt
Dietary Supplement
Lead sponsor
Hydrocephalus and Neuroscience Institute
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Dec 18, 2023 · Synced Jun 11, 2026, 3:53 AM EDT
Completed No phase listed Observational

Maternal-fetal Immune Responses to Fetal Surgery

NCT04484441
View directory record Official record
Conditions
Spina Bifida, Congenital Diaphragmatic Hernia, Lower Urinary Tract Obstructive Syndrome, Myelomeningocele
Interventions
Blood and placenta specimen collection.
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
3
States / cities
Rochester, Minnesota • Cincinnati, Ohio • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Jun 11, 2026, 3:53 AM EDT
Active, not recruiting Not applicable Interventional

Grand Valley State University (GVSU) Skills on Wheels

NCT05339932
View directory record Official record
Conditions
Spina Bifida, Cerebral Palsy, Genetic Disease, Spinal Cord Injuries, Gross Motor Development Delay, Motor Skills Disorders
Interventions
Manual Wheelchair Skills Training
Other
Lead sponsor
Grand Valley State University
Other
Eligibility
5 Years to 17 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Grand Rapids, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 14, 2025 · Synced Jun 11, 2026, 3:53 AM EDT
Recruiting Not applicable Interventional

Transcutaneous Tibial Nerve Stimulation (TTNS) Treatment in Spina Bifida Pediatric Patients With Neurogenic Bladder

NCT06025734
View directory record Official record
Conditions
Spina Bifida
Interventions
Transcutaneous Tibial Nerve Stimulation (TTNS) treatment
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
8 Years to 18 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Jun 11, 2026, 3:53 AM EDT
Completed Not applicable Interventional

Movement-2-Music: Lakeshore Examination of Activity, Disability, and Exercise Response Study

NCT03797378
View directory record Official record
Conditions
Spinal Cord Injuries, Traumatic Brain Injury, Spina Bifida, Cerebral Palsy, Stroke, Parkinson Disease, Multiple Sclerosis
Interventions
eM2M
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 70 Years
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 2, 2025 · Synced Jun 11, 2026, 3:53 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Mobile Health Self-Management and Support System for Chronic and Complex Health Conditions

NCT02592291
View directory record Official record
Conditions
Spinal Cord Injuries, Cerebral Palsy, Spinal Dysraphism, Brain Injuries, Spina Bifida, Traumatic Brain Injury
Interventions
MHealth
Device
Lead sponsor
University of Pittsburgh
Other
Eligibility
12 Years and older
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 2, 2025 · Synced Jun 11, 2026, 3:53 AM EDT
Active, not recruiting Not applicable Interventional

Incontinence and Quality of Life in Children With Spina Bifida

NCT03410667
View directory record Official record
Conditions
Spina Bifida, Myelomeningocele
Interventions
Phase One: Exploration, Phase Two: Creation, Phase Three: Reflection, Aim 3
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
8 Years and older
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Sep 30, 2025 · Synced Jun 11, 2026, 3:53 AM EDT
Completed Not applicable Interventional

Medication Management Among Individuals With Neurodevelopmental Disabilities

NCT03121651
View directory record Official record
Conditions
Spina Bifida, Cerebral Palsy
Interventions
RL-adaptive application
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 99 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 1, 2019 · Synced Jun 11, 2026, 3:53 AM EDT