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ClinicalTrials.gov public records Last synced Oct 21, 2026, 7:37 PM EDT

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Showing 1–24 of 322 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Spinal Fusions Clear all
Terminated Not applicable Interventional

Effectiveness of Lumbar Fusion When NanOss Bioactive Is Used With Posterolateral Gutter Fusions

NCT01452516
View directory record Official record
Conditions
Degenerative Disc Disease, Spinal Stenosis, Spondylolisthesis
Interventions
nanOss Bioactive Bone void filler, Interbody FCage
Device
Lead sponsor
Pioneer Surgical Technology, Inc.
Industry
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
7
States / cities
Beverly Hills, California • La Jolla, California • Chicago, Illinois + 4 more
Source: ClinicalTrials.gov public record
Updated Dec 7, 2016 · Synced Oct 21, 2026, 7:37 PM EDT
Recruiting Phase 3 Interventional

Efficacy and Safety of Novosis Putty in Transforaminal Lumbar Interbody Fusion for Patients With Lumbar Degenerative Disc Disease

NCT07017634
View directory record Official record
Conditions
Degenerative Disc Disease
Interventions
Novosis Putty, Standard of Care
Device · Other
Lead sponsor
CGBio Inc.
Industry
Eligibility
21 Years to 80 Years
Enrollment
316 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
10
States / cities
Little Rock, Arkansas • Sacramento, California • Miami, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Oct 21, 2026, 7:37 PM EDT
Completed Not applicable Interventional Results available

LDR Spine USA Mobi-C(R) Cervical Disc Prosthesis IDE

NCT00389597
View directory record Official record
Conditions
Degenerative Disc Disease
Interventions
Cervical Artificial Disc
Device
Lead sponsor
LDR Spine USA
Industry
Eligibility
18 Years to 69 Years
Enrollment
599 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2015
U.S. locations
24
States / cities
Phoenix, Arizona • Escondido, California • Laguna Hills, California + 21 more
Source: ClinicalTrials.gov public record
Updated Dec 11, 2017 · Synced Oct 21, 2026, 7:37 PM EDT
Terminated No phase listed Observational Results available

Multicenter Study of the Avenue L Interbody Spinal Fusion System Using VerteBRIDGE Plating and Posterior Fixation

NCT02068768
View directory record Official record
Conditions
Degenerative Disc Disease
Interventions
Avenue® L Interbody Fusion System (LDR Spine)
Device
Lead sponsor
LDR Spine USA
Industry
Eligibility
21 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
4
States / cities
Thornton, Colorado • Atlanta, Georgia • Neptune City, New Jersey + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 5, 2019 · Synced Oct 21, 2026, 7:37 PM EDT
Completed Not applicable Interventional

Safety Study of Preservon-Treated Bone Implants for Cervical Fusion in the Treatment of Cervical Radiculopathy or Myelopathy

NCT00344890
View directory record Official record
Conditions
Cervical Radiculopathy, Myelopathy
Interventions
Anterior Cervical Discectomy and Fusion
Procedure
Lead sponsor
LifeNet Health
Industry
Eligibility
18 Years to 65 Years
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 7, 2015 · Synced Oct 21, 2026, 7:37 PM EDT
Terminated Phase 4 Interventional Results available

Erector Spinae Block for Spine Surgery

NCT05417113
View directory record Official record
Conditions
Lumbar Radiculopathy
Interventions
Liposomal bupivacaine, Bupivacaine
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 85 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 29, 2024 · Synced Oct 21, 2026, 7:37 PM EDT
Enrolling by invitation Phase 4 Interventional

Titanium vs. PEEK Fusion Devices in 1 Level TLIF

NCT05691062
View directory record Official record
Conditions
Spine Fusion, Lumbar Spondylolisthesis, Lumbar Stenosis
Interventions
Titanium Fusion Device, PEEK Fusion Device
Device
Lead sponsor
Twin Cities Spine Center
Other
Eligibility
18 Years to 70 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 24, 2025 · Synced Oct 21, 2026, 7:37 PM EDT
Terminated No phase listed Observational

Single Position Spine Surgery Registry

NCT04839783
View directory record Official record
Conditions
Spine Fusion, Spinal Stenosis, Degenerative Disc Disease
Interventions
Not listed
Lead sponsor
Spine and Scoliosis Research Associates
Other
Eligibility
18 Years to 100 Years
Enrollment
234 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
5
States / cities
Boston, Massachusetts • New York, New York • Wilmington, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 20, 2025 · Synced Oct 21, 2026, 7:37 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Prospective Clinical Evaluation of the New Aegis Plate for Anterior Interbody Fusions

NCT00555659
View directory record Official record
Conditions
Degeneration, Spondylosis, Spondylolithesis, Stenosis
Interventions
Not listed
Lead sponsor
Columbia Orthopaedic Group, LLP
Other
Eligibility
18 Years to 75 Years
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2013
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 12, 2013 · Synced Oct 21, 2026, 7:37 PM EDT
Recruiting No phase listed Observational

Intraoperative Monitoring for the Lateral Lumbar Interbody Fusion Procedure

NCT05648474
View directory record Official record
Conditions
Intervertebral Disc Degeneration, Stenosis, Spinal, Spondylolisthesis, Spinal Deformity, Spinal Instability
Interventions
Somatosensory evoked potential [SSEP] intraoperative monitoring
Diagnostic Test
Lead sponsor
Alphatec Spine, Inc.
Industry
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Carlsbad, California
Source: ClinicalTrials.gov public record
Updated Oct 24, 2024 · Synced Oct 21, 2026, 7:37 PM EDT
Completed No phase listed Observational

Trinity Evolution in Anterior Cervical Disectomy and Fusion (ACDF)

NCT00951938
View directory record Official record
Conditions
Degenerative Disc Disease
Interventions
Not listed
Lead sponsor
Orthofix Inc.
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
13
States / cities
Encinitas, California • Redding, California • Parker, Colorado + 10 more
Source: ClinicalTrials.gov public record
Updated Apr 8, 2014 · Synced Oct 21, 2026, 7:37 PM EDT
Not listed Not applicable Interventional

OSTEOAMP Lumbar Fusion Intra-Patient Controlled Study

NCT05405374
View directory record Official record
Conditions
Lumbar Spine Disease, Lumbar Spondylolisthesis, Lumbar Spine Instability, Lumbar Spondylosis, Degenerative Disc Disease
Interventions
OSTEOAMP, Infuse
Other · Device
Lead sponsor
Bioventus LLC
Industry
Eligibility
21 Years to 80 Years
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
9
States / cities
New Haven, Connecticut • Wichita, Kansas • Paducah, Kentucky + 6 more
Source: ClinicalTrials.gov public record
Updated Aug 28, 2023 · Synced Oct 21, 2026, 7:37 PM EDT
Recruiting No phase listed Observational

Thoracic-Lumbar Arthrodesis- Implanet Jazz

NCT05366140
View directory record Official record
Conditions
Spondylolisthesis, Spinal Stenosis, Degenerative Disease
Interventions
Prospective follow-up of patients who have received instrumented lumbar arthrodesis supplemented the Implanet Jazz System(TM)
Other
Lead sponsor
Francis Farhadi
Other
Eligibility
18 Years to 100 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Oct 27, 2025 · Synced Oct 21, 2026, 7:37 PM EDT
Completed Phase 4 Interventional

Perioperative Steroid Dosing on the APR in AIS

NCT05561725
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis (AIS)
Interventions
Dexamethasone postoperative, Standard of Care
Drug
Lead sponsor
Emory University
Other
Eligibility
10 Years to 18 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 21, 2026, 7:37 PM EDT
Completed Phase 3 Interventional Results available

Performance of the Hedrocel(R) Cervical Fusion Device

NCT00758758
View directory record Official record
Conditions
Symptomatic Cervical Disc Disease
Interventions
Anterior Cervical Discectomy and Fusion
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years to 70 Years
Enrollment
231 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2009
U.S. locations
13
States / cities
Los Angeles, California • Clearwater, Florida • Orlando, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Aug 23, 2013 · Synced Oct 21, 2026, 7:37 PM EDT
Recruiting Not applicable Interventional

Trans-Auricular Stimulation for Postoperative Inflammation in Spine Surgery

NCT07218133
View directory record Official record
Conditions
Spinal Fusion, Hyperglycemia, Postoperative Pain Management, Postoperative Care, Spine Disease, Neurologic Deficits, Neurological Disorder, Inflammation, Spine Condition, Spinal (Fusion) Surgery, Cytokine Levels, Spine Fusion
Interventions
Auricular vagus nerve stimulation, Sham Auricular Vagus nerve Stimulation
Device
Lead sponsor
Alexander T. Yahanda
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Oct 21, 2026, 7:37 PM EDT
Completed Not applicable Interventional

Coping After Pediatric Scoliosis Surgery

NCT04063670
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis
Interventions
Video Intervention, Control
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
11 Years to 18 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 2, 2025 · Synced Oct 21, 2026, 7:37 PM EDT
Withdrawn Phase 1Phase 2 Interventional Accepts healthy volunteers

Effect of RECK in Posterior Spinal Fusion

NCT06447194
View directory record Official record
Conditions
Degenerative Lumbar Spinal Stenosis, Degenerative Disc Disease, Degenerative Spondylolisthesis, Degenerative Disease
Interventions
Ropivacaine, Epinephrine, Clonidine, and Ketorolac Injection Cocktail, Placebo
Drug · Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 88 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 31, 2025 · Synced Oct 21, 2026, 7:37 PM EDT
Not listed No phase listed Observational

Prospective Study of Safety and Efficacy of InQu® Bone Graft Extender in Lumbar Interbody Fusion Surgery

NCT02400762
View directory record Official record
Conditions
Intervertebral Disc Degeneration
Interventions
Not listed
Lead sponsor
ISTO Technologies, Inc.
Industry
Eligibility
18 Years and older
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
2
States / cities
Los Angeles, California • Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 31, 2017 · Synced Oct 21, 2026, 7:37 PM EDT
Not listed Not applicable Interventional

Massage Therapy After Thoracic or Lumbar Surgery

NCT06424158
View directory record Official record
Conditions
Scoliosis; Adolescence, Adolescent Idiopathic Scoliosis, Thoracic Region, Adolescent Idiopathic Scoliosis, Lumbar Region
Interventions
Massage Therapy
Other
Lead sponsor
Cook Children's Health Care System
Other
Eligibility
7 Years to 19 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated May 23, 2024 · Synced Oct 21, 2026, 7:37 PM EDT
Terminated Not applicable Interventional Results available

Dynesys Spinal System Post Market 522 Study

NCT01528072
View directory record Official record
Conditions
Degenerative Spondylolisthesis, Pseudoarthrosis
Interventions
Dynesys Spinal System
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
20 Years to 80 Years
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
9
States / cities
Belleville, Illinois • Baltimore, Maryland • New York, New York + 5 more
Source: ClinicalTrials.gov public record
Updated Jan 29, 2020 · Synced Oct 21, 2026, 7:37 PM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers Results available

Propofol + Remifentanil vs. Propofol + Dexmedetomidine in Adolescent Idiopathic Scoliosis Patients Having Spine Surgery

NCT06096181
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis, Multimodal Analgesia, Opioid Induced Hyperalgesia, Remifentanil, Dexmedetomidine, Posterior Spinal Fusion
Interventions
Remifentanil TIVA, Dexmedetomidine TIVA, Propofol TIVA
Drug
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
12 Years to 18 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 10, 2025 · Synced Oct 21, 2026, 7:37 PM EDT
Completed Not applicable Interventional Results available

BMAC & Allograft vs BMP-2

NCT02924571
View directory record Official record
Conditions
Spinal Fusion
Interventions
Bone Marrow Aspirate Concentrate (BMAC) + Allograft, Recombinant Human Bone Morphogenetic Protein-2 (BMP), Autograft
Device · Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 8, 2025 · Synced Oct 21, 2026, 7:37 PM EDT
Completed Phase 1Phase 2 Interventional

Study of Intra-articular Delivery of tgAAC94 in Inflammatory Arthritis Subjects

NCT00126724
View directory record Official record
Conditions
Arthritis, Rheumatoid, Arthritis, Psoriatic, Ankylosing Spondylitis
Interventions
tgAAC94 gene therapy vector, tgAAC94 placebo
Genetic
Lead sponsor
Targeted Genetics Corporation
Industry
Eligibility
18 Years to 75 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
22
States / cities
Glendale, Arizona • Tuscon, Arizona • Palm Desert, California + 18 more
Source: ClinicalTrials.gov public record
Updated Jul 29, 2009 · Synced Oct 21, 2026, 7:37 PM EDT