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Showing 1–24 of 313 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Spinal Fusions Clear all
Completed No phase listed Observational

Re-operation Rates of Concorde Bullet Device Versus Conduit Titanium Interbody Graft for Lumbar Fusion

NCT05993195
View directory record Official record
Conditions
Degenerative Spondylolisthesis, Lumbar Spondylosis, Lumbar Spondylolisthesis
Interventions
Conduit Titanium Interbody Graft, Concorde Bullet Device
Device
Lead sponsor
Lahey Clinic
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Burlington, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 2, 2024 · Synced Jul 22, 2026, 9:10 AM EDT
Completed Not applicable Interventional Results available

OsteoStrux™ Collagen Ceramic Scaffold in Instrumented Lumbar Spine Fusion

NCT01873586
View directory record Official record
Conditions
Degenerative Changes, Stenosis, Spondylosis
Interventions
Posterolateral Fusion
Procedure
Lead sponsor
SeaSpine, Inc.
Industry
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Kenmore, New York
Source: ClinicalTrials.gov public record
Updated Jun 16, 2019 · Synced Jul 22, 2026, 9:10 AM EDT
Completed No phase listed Observational

Osteocel® Plus in Transforaminal Lumbar Interbody Fusion (TLIF)

NCT00947583
View directory record Official record
Conditions
Degenerative Disc Disease
Interventions
Osteocel Plus
Biological
Lead sponsor
NuVasive
Industry
Eligibility
18 Years to 70 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 23, 2025 · Synced Jul 22, 2026, 9:10 AM EDT
Suspended Not applicable Interventional

Evaluation of the PediGuard™ for Pedicle Screw Insertion

NCT00549627
View directory record Official record
Conditions
Posterior Spinal Fusion
Interventions
Pediguard
Device
Lead sponsor
Shriners Hospitals for Children
Other
Eligibility
Not listed
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
6
States / cities
Golden, Colorado • Miami, Florida • Louisville, Kentucky + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 3, 2009 · Synced Jul 22, 2026, 9:10 AM EDT
Withdrawn Not applicable Interventional

Methadone Versus Placebo in Spine Fusion

NCT01125059
View directory record Official record
Conditions
Postoperative Pain
Interventions
Methadone, Saline
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 21, 2015 · Synced Jul 22, 2026, 9:10 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Changes in Cerebral Oxygenation During the Administration of Cell Saver Blood and Allogeneic Blood

NCT02607150
View directory record Official record
Conditions
Idiopathic Scoliosis, Transfusion Reaction
Interventions
Cerebral Oxygenation Changes
Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
Not listed
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 6, 2016 · Synced Jul 22, 2026, 9:10 AM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Ketorolac on Posterior Thoracolumbar Spinal Fusions

NCT03278691
View directory record Official record
Conditions
Thoracolumbar Spinal Fusions
Interventions
Saline, Ketorolac
Drug
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2025
U.S. locations
1
States / cities
Southfield, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 19, 2023 · Synced Jul 22, 2026, 9:10 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Multimodal Analgesia Versus Routine Care Pain Management

NCT01861743
View directory record Official record
Conditions
Degenerative Disc Disease Lumbar, Spinal Stenosis, Lumbar Spondylolisthesis
Interventions
Multimodal Analgesia, Patient controlled analgesia
Other
Lead sponsor
Rush University Medical Center
Other
Eligibility
Not listed
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 28, 2018 · Synced Jul 22, 2026, 9:10 AM EDT
Completed Phase 2 Interventional

Safety and Preliminary Efficacy Study of NeoFuse in Subjects Undergoing Multi-Level Anterior Cervical Discectomy

NCT01097486
View directory record Official record
Conditions
Cervical Degenerative Disc Disease, Degenerative Spondylolisthesis, Spinal Stenosis
Interventions
NeoFuse, Allograft
Biological · Procedure
Lead sponsor
Mesoblast, Ltd.
Industry
Eligibility
18 Years to 70 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
8
States / cities
Sacramento, California • Santa Monica, California • Denver, Colorado + 5 more
Source: ClinicalTrials.gov public record
Updated Aug 15, 2019 · Synced Jul 22, 2026, 9:10 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Clinical Evaluation of GENEX® DS in Instrumented Posterolateral Fusion

NCT02317185
View directory record Official record
Conditions
Degenerative Disc Disease, Spondylolisthesis, Stenosis
Interventions
genex bone graft with bone graft, autogenous bone graft
Device · Other
Lead sponsor
Spine Wave
Industry
Eligibility
18 Years to 75 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
2
States / cities
New York, New York • Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 18, 2018 · Synced Jul 22, 2026, 9:10 AM EDT
Active, not recruiting No phase listed Observational

Pelvic Fixation and Fusion During Multilevel Spinal Surgery

NCT05640908
View directory record Official record
Conditions
Spinal Fusion, Deformity of Spine
Interventions
iFuse Bedrock Granite Implant System
Device
Lead sponsor
SI-BONE, Inc.
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
9
States / cities
Mobile, Alabama • Aurora, Colorado • Royal Oak, Michigan + 6 more
Source: ClinicalTrials.gov public record
Updated Jan 22, 2026 · Synced Jul 22, 2026, 9:10 AM EDT
Completed Phase 3 Interventional Results available

Analgesic Efficacy of Repeated Doses of Intravenous (IV) Acetaminophen in Post-operative Pediatric Spine Fusion Patients

NCT01394718
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Intravenous Acetaminophen, Placebo
Drug · Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
10 Years to 18 Years
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 17, 2016 · Synced Jul 22, 2026, 9:10 AM EDT
Completed No phase listed Observational

Return to Sport After Posterior Spinal Fusion

NCT03513120
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis, Posterior Spinal Fusion
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
10 Years to 18 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 18, 2020 · Synced Jul 22, 2026, 9:10 AM EDT
Terminated Phase 3 Interventional Results available

DIAM™ Spinal Stabilization System vs. Decompression, Formerly vs. Posterolateral Fusion

NCT00627497
View directory record Official record
Conditions
Degenerative Lumbar Spinal Stenosis
Interventions
Single-Level Posterior Decompression, DIAM Spinal Stabilization, Fusion
Procedure · Device
Lead sponsor
Medtronic Spinal and Biologics
Industry
Eligibility
35 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
9
States / cities
Fremont, California • Jacksonville, Florida • Melbourne, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Jan 4, 2021 · Synced Jul 22, 2026, 9:10 AM EDT
Withdrawn Not applicable Interventional

Clinical Outcome and Fusion Results Using the VerteLoc® Facet Fixation Device

NCT01892878
View directory record Official record
Conditions
Spinal Stenosis
Interventions
VerteLoc
Procedure
Lead sponsor
VG Innovations, LLC
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Grand Blanc, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 15, 2018 · Synced Jul 22, 2026, 9:10 AM EDT
Withdrawn Phase 2Phase 3 Interventional

Hypertonic Saline in Posterior Spinal Fusion

NCT06822374
View directory record Official record
Conditions
Scoliosis Idiopathic, Scoliosis;Congenital
Interventions
Normosol-R, buffered 2% hypertonic saline
Drug
Lead sponsor
Joseph D. Tobias
Other
Eligibility
10 Years to 25 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 9, 2025 · Synced Jul 22, 2026, 9:10 AM EDT
Active, not recruiting Phase 2 Interventional

Abaloparatide vs. Placebo in Post-Menopausal Women and Abaloparatide in Men Receiving Initial Spinal Fusion Surgery

NCT03841058
View directory record Official record
Conditions
Spinal Fusion
Interventions
Abaloparatide, Placebo
Drug
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
50 Years and older
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Jul 22, 2026, 9:10 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Postoperative subQ Pain Control for Spinal Fusion Surgery

NCT03476811
View directory record Official record
Conditions
Spine Fusion, Surgery, Pain, Postoperative
Interventions
0.25% Marcaine at 2ml/hr and pain medications, Placement of OnQ Drug pump
Drug · Device
Lead sponsor
University of Arizona
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated May 25, 2022 · Synced Jul 22, 2026, 9:10 AM EDT
Completed Phase 4 Interventional Results available

Skeletal Muscle and Adipose Tissue Study

NCT03190668
View directory record Official record
Conditions
Idiopathic Scoliosis
Interventions
Bolus dose of Cefazolin, Continuous Cefazolin drip, Paraspinal muscle microdialysis catheters, Subcutaneous microdialysis catheters
Drug · Device
Lead sponsor
University of Florida
Other
Eligibility
12 Years to 20 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 10, 2023 · Synced Jul 22, 2026, 9:10 AM EDT
Terminated Not applicable Interventional

A Prospective Study of NuCel® in Cervical Spine Fusion

NCT02381067
View directory record Official record
Conditions
Spondylosis, Spinal Stenosis, Spondylolisthesis, Intervertebral Disc Disease, Intervertebral Disc Degeneration
Interventions
NuCel with Allograft Bone
Other
Lead sponsor
NuTech Medical, Inc
Industry
Eligibility
21 Years and older
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Marietta, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 17, 2020 · Synced Jul 22, 2026, 9:10 AM EDT
Not listed Phase 1Phase 2 Interventional

Safety Evaluation of ART352-L in Subjects Undergoing Posterolateral Spinal Fusion

NCT04378543
View directory record Official record
Conditions
Degenerative Spondylolisthesis
Interventions
ART352-L
Biological
Lead sponsor
Ankasa Regenerative Therapeutics, Inc.
Industry
Eligibility
50 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
3
States / cities
Los Angeles, California • Rochester, Minnesota • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 11, 2020 · Synced Jul 22, 2026, 9:10 AM EDT
Completed Not applicable Interventional

OP-1 Putty for Posterolateral Fusions

NCT00677950
View directory record Official record
Conditions
Degenerative Lumbar Spondylolisthesis
Interventions
Spinal fusion
Procedure
Lead sponsor
Olympus Biotech Corporation
Industry
Eligibility
18 Years to 85 Years
Enrollment
336 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2005
U.S. locations
21
States / cities
Santa Monica, California • Stanford, California • Denver, Colorado + 18 more
Source: ClinicalTrials.gov public record
Updated Jun 9, 2011 · Synced Jul 22, 2026, 9:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Prospective, Multi-center Study to Assess Posterolateral Fusion Using FIBERGRAFT

NCT03884283
View directory record Official record
Conditions
Degenerative Disc Disease, Spondylolisthesis, Spinal Stenosis Lumbar
Interventions
FIBERGRAFT BG Matrix
Device
Lead sponsor
Prosidyan, Inc.
Industry
Eligibility
18 Years and older
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
9
States / cities
Long Beach, California • Wellington, Florida • Paducah, Kentucky + 5 more
Source: ClinicalTrials.gov public record
Updated Apr 21, 2024 · Synced Jul 22, 2026, 9:10 AM EDT
Withdrawn Phase 1Phase 2 Interventional

Safety and Efficacy Study of NeoFuse in Subjects Requiring Posterolateral Lumbar Fusion

NCT00810212
View directory record Official record
Conditions
Degenerative Disc Disease, Degenerative Spondylolisthesis, Spinal Stenosis
Interventions
PLF with autograft, PLF with NeoFuse
Procedure · Biological
Lead sponsor
Mesoblast, Ltd.
Industry
Eligibility
18 Years to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Plano, Texas
Source: ClinicalTrials.gov public record
Updated Jun 1, 2020 · Synced Jul 22, 2026, 9:10 AM EDT