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Showing 961–984 of 1,167 matching trials from the live ClinicalTrials.gov search.
Completed Not applicable Interventional Results available

Hand Function for Tetraplegia

NCT00890916
Conditions
Spinal Cord Injury, Tetraplegia
Interventions
FIRSTHAND System
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2021
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Spinal Cord Injuries
Interventions
Exoskeletal assisted walking, Epidural Stimulation, Resistance Training, delayed-ES, no-Resistance training
Device · Procedure
Lead sponsor
United States Department of Defense
Federal
Eligibility
18 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Richmond, Virginia
Conditions
Spinal Cord Injury
Interventions
Crossover of vasopressors
Other
Lead sponsor
University of British Columbia
Other
Eligibility
17 Years and older
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2020
U.S. locations
1
States / cities
San Francisco, California
Conditions
Spinal Cord Injuries (SCI)
Interventions
Sham AIH, Acute Intermittent Hypoxia (AIH) 15, Acute Intermittent Hypoxia (AIH) 23
Other
Lead sponsor
Milap Sandhu
Other
Eligibility
18 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Enrolling by invitation No phase listed Observational

Posterior Cervical Fixation Study

NCT04770571
Conditions
Degenerative Disc Disease, Craniocervical Injuries, Cervical Radiculopathy, Cervical Disc Disease, Cervical Fusion, Cervical Spine Disease, Cervical Myelopathy, Cervical Instabilities Spine, Thoracic Injury
Interventions
observational study
Device
Lead sponsor
NuVasive
Industry
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
7
States / cities
Orange, California • Hartford, Connecticut • Hyattsville, Maryland + 4 more
Conditions
Spinal Cord Injuries, Cognitive Dysfunction, Cognitive Impairment, Acute Spinal Cord Injury
Interventions
game-like computerized activities, Placebo
Behavioral
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 59 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
3
States / cities
Englewood, Colorado • East Hanover, New Jersey • Seattle, Washington
Conditions
Tethered Cord, Tethered Cord Syndrome, Occult Spina Bifida, Spina Bifida Occulta
Interventions
Release of filum terminale
Procedure
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
2 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
New York, New York
Completed Phase 4 Interventional Accepts healthy volunteers

Lower Limb Function After Spinal Cord Injury

NCT02635893
Conditions
Spinal Cord Injury
Interventions
D-Cycloserine, Placebo, Training, Stimulation, Placebo Stimulation
Drug · Other
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 85 Years
Enrollment
257 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Recruiting Phase 1 Interventional Accepts healthy volunteers

Spinal Cord Injury Neuroprotection With Glyburide

NCT05426681
Conditions
Acute Spinal Cord Injury
Interventions
GlyBURIDE Oral Tablet
Drug
Lead sponsor
Francis Farhadi
Other
Eligibility
18 Years to 80 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2028
U.S. locations
1
States / cities
Lexington, Kentucky
Conditions
Spinal Cord Injuries
Interventions
WI program, WI Program Reminder, JITAI Goal Setting, JITAI physical activity message, Notification EMA, End of day EMA, Wake up time EMA, Weekly PA Information, Daily PA Information
Behavioral · Other
Lead sponsor
Temple University
Other
Eligibility
18 Years to 75 Years
Enrollment
196 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Spinal Cord Injury, Traumatic Spinal Cord Injury, Paraplegia and Tetraplegia, Metabolic Syndrome
Interventions
Galantamine Hydrobromide Extended Release
Drug
Lead sponsor
Northwell Health
Other
Eligibility
21 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
3
States / cities
West Orange, New Jersey • Manhasset, New York • The Bronx, New York
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Remote Ischemic Conditioning on Hand Use in Individuals With SCI and ALS

NCT03851302
Conditions
Spinal Cord Injuries, Amyotrophic Lateral Sclerosis
Interventions
Active Remote Ischemic Conditioning, Sham Remote Ischemic Conditioning, Isometric hand exercise
Other
Lead sponsor
Bronx VA Medical Center
Federal
Eligibility
18 Years to 75 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
The Bronx, New York
Completed Not applicable Interventional Results available

Musculoskeletal Plasticity After Spinal Cord Injury

NCT02622295
Conditions
Spinal Cord Injuries
Interventions
Single-session electrically induced exercise, Electrically-induced exercise training
Behavioral
Lead sponsor
Richard K Shields
Other
Eligibility
21 Years to 60 Years
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Spinal Cord Injury
Interventions
Exercise
Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 65 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Miami, Florida
Conditions
Spinal Cord Injuries
Interventions
tsDCS+pDCS, Low-level laser therapy
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Spinal Cord Injuries, Constipation, Neurogenic Bowel
Interventions
Neostigmine and Glycopyrrolate, Iontophoresis
Drug · Device
Lead sponsor
James J. Peters Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 75 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
The Bronx, New York
Conditions
Amyotrophic Lateral Sclerosis
Interventions
Virtual Seating Coach
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Charlotte, North Carolina
Conditions
Cervical Spine Injury
Interventions
Not listed
Lead sponsor
Julie Leonard
Other
Eligibility
Up to 18 Years
Enrollment
22,444 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
18
States / cities
Los Angeles, California • Oakland, California • Sacramento, California + 14 more
Recruiting Not applicable Interventional

Nomad P-KAFO Study

NCT05644522
Conditions
Cerebrovascular Accident, Post-polio Syndrome, Spinal Cord Injuries, Multiple Sclerosis, Muscular Dystrophy, Paralysis
Interventions
Indego Nomad® Powered Knee-Ankle-Foot Orthosis (P-KAFO) (Parker Hannifin Corp., Cleveland, OH)
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 89 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Spinal Cord Injuries
Interventions
Cervical Transcutaneous Electrical Spinal Cord Stimulation
Device
Lead sponsor
University of Louisville
Other
Eligibility
18 Years to 75 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Louisville, Kentucky
Conditions
Spinal Cord Injury
Interventions
Transcranial direct current stimulation + step training, Sham transcranial direct current stimulation + step training
Device · Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Miami, Florida
Conditions
Spinal Cord Injuries
Interventions
Acute Intermittent Hypoxia
Other
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 70 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Completed Not applicable Interventional Accepts healthy volunteers

Brain Plus Spinal Stimulation for Cervical SCI

NCT04727866
Conditions
Spinal Cord Injuries, Spinal Cord Injury at C5-C7 Level, Tetraplegia/Tetraparesis
Interventions
transcutaneous spinal direct current stimulation (tsDCS) - coronal, transcutaneous spinal direct current stimulation (tsDCS) - caudal, transcutaneous spinal direct current stimulation (tsDCS) - rostral, intermittent theta burst stimulation (iTBS)
Device
Lead sponsor
Bronx VA Medical Center
Federal
Eligibility
18 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
The Bronx, New York
Recruiting Not applicable Interventional

Multi-speed Ergonomic Wheelchair

NCT05776030
Conditions
Spinal Cord Diseases, Spinal Cord Injuries
Interventions
Single Speed Ergonomic Wheelchair, Multi-Speed Ergonomic Wheelchair
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota