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ClinicalTrials.gov public records Last synced Sep 9, 2026, 12:36 AM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Leukemia-Lymphoma
Interventions
EMLA, Lidocaine
Drug
Lead sponsor
CAMC Health System
Other
Eligibility
3 Years to 18 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Charleston, West Virginia
Conditions
Post-Lumbar Puncture Headache
Interventions
Epidural Blood Patch
Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 65 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Houston, Texas
Conditions
Arnold Chiari Deformity, Hydrocephalus, Syringomyelia
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1992 – 2011
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
HER2 Positive Untreated Metastatic Breast Cancer, Asymptomatic or Low Symptomatic Brain Metastasis in Breast Cancer
Interventions
Pertuzumab, Trastuzumab
Drug
Lead sponsor
Kimberly Blackwell
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Lumbar Puncture
Interventions
Compass Lumbar Puncture Enhanced
Device
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
Up to 18 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2011
U.S. locations
1
States / cities
Seattle, Washington
Conditions
Leukemia
Interventions
Ultrasound
Procedure
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
Not listed
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Columbus, Ohio
Terminated No phase listed Observational Accepts healthy volunteers

Collection of Cerebrospinal Fluid in Healthy Children

NCT01698229
Conditions
Late Infantile Neuronal Ceroid Lipofuscinosis, Batten Disease
Interventions
Group 1
Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
2 Years to 8 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effect of Bedside Ultrasound Assistance on the Proportion of Successful Infant Spinal Taps

NCT02133066
Conditions
Traumatic Lumbar Puncture
Interventions
Bedside Ultrasound-Assisted Site Marking, Mindray M7 Ultrasound, Routine lumbar puncture
Procedure · Device
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
Up to 6 Months
Enrollment
128 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Completed No phase listed Observational Accepts healthy volunteers

Herpes Virus-6 and Epilepsy

NCT00085683
Conditions
Epilepsy
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Completed Not applicable Interventional Results available

VerTouch Device: A Prospective Randomized Controlled Trial

NCT04630171
Conditions
Pregnancy, Pain
Interventions
Group #1: VerTouch utilized for identification of site for labor epidural or spinal anesthesia procedure, Group #2: Ultrasound (US) utilized for identification of site for labor epidural or spinal anesthesia procedure, Group #3: Control group, palpation utilized for identification of site for labor epidural or spinal anesthesia procedure
Device · Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Leukemia
Interventions
Virtual Reality
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
10 Years to 25 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Aurora, Colorado
Completed Not applicable Interventional Results available

Needle-Free Jet Injection of Lidocaine During Lumbar Puncture

NCT01224431
Conditions
Pain
Interventions
Buffered Lidocaine J-tip
Drug
Lead sponsor
Phoenix Children's Hospital
Other
Eligibility
Up to 90 Days
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Phoenix, Arizona
Terminated Not applicable Interventional Accepts healthy volunteers

Ultrasound-Assisted Lumbar Puncture

NCT03167190
Conditions
Spinal Puncture, Diagnostic Imaging
Interventions
Point-of-care ultrasound, Traditional Landmark-based Lumbar Puncture
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Jacksonville, Florida
Completed Not applicable Interventional Accepts healthy volunteers Results available

Incidence of Headache Following an Unintentional Dural Puncture

NCT01977898
Conditions
Postdural Puncture Headache, Post-Lumbar Puncture Headache, Cerebrospinal Fluid Leaks
Interventions
Morphine, Saline
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Completed Phase 2 Interventional

SHAPE for ICP Assessment

NCT06571786
Conditions
Lumbar Puncture
Interventions
Perflutren lipid microsphere
Drug
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
2
States / cities
Rochester, Minnesota • Philadelphia, Pennsylvania
Conditions
Labor Pain
Interventions
Ropivacaine 0.1% Injectable Solution, Bupivacaine 0.25% Injectable Solution
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Acute Lymphoblastic Leukemia, Pediatric
Interventions
Use of Virtual Reality Headset
Other
Lead sponsor
Children's National Research Institute
Other
Eligibility
7 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Conditions
Malignant Neoplasm
Interventions
placebo administration, EMLA, propofol, fentanyl citrate
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
Up to 22 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Conditions
Attention Deficit and Disruptive Behavior Disorder, Attention Deficit Disorder With Hyperactivity
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
6 Years to 17 Years
Enrollment
347 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1985 – 2017
U.S. locations
1
States / cities
Bethesda, Maryland
Completed Not applicable Interventional Results available

Lumbar Puncture and Syphilis Outcome

NCT02031146
Conditions
Syphilis
Interventions
Lumbar puncture
Procedure
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
231 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
1
States / cities
Seattle, Washington
Conditions
Pain
Interventions
Lidocaine Cream 4%, Placebo
Drug
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
0 Days to 60 Days
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Buffalo, New York
Conditions
Post-Lumbar Puncture Headache
Interventions
Modified Lumbar Puncture
Procedure
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Houston, Texas
Completed Not applicable Interventional Accepts healthy volunteers Results available

Ultrasound vs Palpation for Infant Lumbar Puncture

NCT02373774
Conditions
Spinal; Puncture, Complications
Interventions
Ultrasound
Device
Lead sponsor
Columbia University
Other
Eligibility
Up to 90 Days
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Accepts healthy volunteers

Variability of Infant LP Insertion Site Based On Procedural Experience

NCT02949869
Conditions
Traumatic Lumbar Puncture
Interventions
Spinal Sonography
Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
Up to 12 Months
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts