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ClinicalTrials.gov public records Last synced Oct 22, 2026, 5:25 AM EDT

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Showing 265–288 of 510 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Spine Condition Clear all
Not listed Phase 4 Interventional Accepts healthy volunteers

Pain Control After Lumbar Spine Fusion

NCT06484192
View directory record Official record
Conditions
Spine Fusion, NSAID (Non-Steroidal Anti-Inflammatory Drug), Postoperative Pain
Interventions
Naproxen 500 Mg, Ketorolac, OxyCODONE 5 mg Oral Tablet, Metaxalone 800 MG
Drug
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
18 Years and older
Enrollment
428 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 3, 2024 · Synced Oct 22, 2026, 5:25 AM EDT
Completed No phase listed Observational

Metastatic Tumor Research and Outcomes Network

NCT02830451
View directory record Official record
Conditions
Metastatic Spine Tumor
Interventions
Not listed
Lead sponsor
AO Innovation Translation Center
Other
Eligibility
18 Years and older
Enrollment
2,417 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2026
U.S. locations
10
States / cities
San Francisco, California • Chicago, Illinois • Baltimore, Maryland + 7 more
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 22, 2026, 5:25 AM EDT
Completed No phase listed Observational

A Prospective Non-concurrent Controlled Evaluation of Open and MAS® PLIF

NCT01640977
View directory record Official record
Conditions
Lumbar Degenerative Disc Disease
Interventions
Open PLIF (posterior lumbar interbody fusion), MAS PLIF
Procedure
Lead sponsor
NuVasive
Industry
Eligibility
18 Years and older
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
4
States / cities
Greensboro, North Carolina • York, Pennsylvania • Temple, Texas
Source: ClinicalTrials.gov public record
Updated Dec 24, 2025 · Synced Oct 22, 2026, 5:25 AM EDT
Completed Not applicable Interventional Results available

The Value of Home Chlorhexidine Pre-Surgical Wash Before Spine Surgery

NCT02767427
View directory record Official record
Conditions
Infection, Spinal Injuries
Interventions
Chlorhexidine Wipes, No intervention
Device · Other
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 6, 2023 · Synced Oct 22, 2026, 5:25 AM EDT
Completed Not applicable Interventional Results available

Stereotactic Body Radiation Therapy (SBRT) in Metastatic Non-small Cell Lung Cancer

NCT01185639
View directory record Official record
Conditions
Non-Small-Cell Lung Carcinoma, Liver Cancer, Adrenal Cancer
Interventions
stereotactic body radiation therapy
Radiation
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 90 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
2
States / cities
Wilmington, North Carolina • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 29, 2019 · Synced Oct 22, 2026, 5:25 AM EDT
Completed Not applicable Interventional

Regional Manual Therapy and Motor Control Exercise for Chronic Low Back Pain

NCT02170753
View directory record Official record
Conditions
Low Back Pain, Musculoskeletal Pain
Interventions
Regional manual therapy, Standard physical therapy
Procedure
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jun 27, 2016 · Synced Oct 22, 2026, 5:25 AM EDT
Recruiting Phase 4 Interventional

Effect of Magnesium on Neuromonitoring

NCT06975072
View directory record Official record
Conditions
Spine, Pain, Spine Surgery, Spine Surgery With Neuromonitoring, Spine Surgery With Motor Evoked Potential Monitoring, Spine Fusion
Interventions
Magnesium sulfate administration
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 21, 2026 · Synced Oct 22, 2026, 5:25 AM EDT
Completed Not applicable Interventional

Multicenter Study for Robotic Arm-assisted THA 4.0 System: Hip Spine Relationship

NCT04646096
View directory record Official record
Conditions
Osteoarthritis, Hip, Hip Disease
Interventions
MAKO THA 4.0 System
Device
Lead sponsor
American Hip Institute
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Des Plaines, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 29, 2025 · Synced Oct 22, 2026, 5:25 AM EDT
Completed Phase 4 Interventional

Study to Evaluate the Safety, Efficacy and Pharmacokinetics of Optimark (Gadoversetamide) in Pediatric Patients

NCT01092754
View directory record Official record
Conditions
Pathological Processes
Interventions
MRI, Gadoversetamide
Procedure · Drug
Lead sponsor
Guerbet
Industry
Eligibility
2 Years to 18 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2003
U.S. locations
12
States / cities
Little Rock, Arkansas • San Diego, California • Miami, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Aug 1, 2017 · Synced Oct 22, 2026, 5:25 AM EDT
Not listed No phase listed Observational

NOC2 Spine Registry

NCT02187666
View directory record Official record
Conditions
Spinal Disease
Interventions
Not listed
Lead sponsor
DC2 Healthcare
Industry
Eligibility
Not listed
Enrollment
10,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2011
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 11, 2014 · Synced Oct 22, 2026, 5:25 AM EDT
Completed Phase 4 Interventional Results available

A Study That Will Compare the Effect of Two Drugs on Participants With Low Bone Mass and a Recent Hip Fracture

NCT00887354
View directory record Official record
Conditions
Osteoporosis
Interventions
Teriparatide, Risedronate, Placebo, Calcium, Vitamin D
Drug · Dietary Supplement
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
50 Years and older
Enrollment
224 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
6
States / cities
Fort Lauderdale, Florida • New Port Richey, Florida • Orlando, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 25, 2019 · Synced Oct 22, 2026, 5:25 AM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Post-Operative Pain Management Following Spine Surgery

NCT03076710
View directory record Official record
Conditions
Pain Management, Analgesia, Anesthetic
Interventions
Opioids delivered through PCA, EXPAREL® infiltration
Drug
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jul 2, 2020 · Synced Oct 22, 2026, 5:25 AM EDT
Withdrawn Not applicable Interventional

Magnetic Resonance Imaging of the Spine

NCT01382290
View directory record Official record
Conditions
Tethered Cord, Chiari I Malformation
Interventions
MRI
Procedure
Lead sponsor
Children's Healthcare of Atlanta
Other
Eligibility
Up to 18 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 9, 2016 · Synced Oct 22, 2026, 5:25 AM EDT
Completed Not applicable Interventional Results available

Spine Pain INtervention to Enhance Care Quality And Reduce Expenditure

NCT03083886
View directory record Official record
Conditions
Back Pain, Neck Pain
Interventions
Identify, Coordinated, Enhanced (ICE) Decision Making + PCP led care, Individualized Postural Therapy (IPT) + PCP led care, Usual PCP led care
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
3,087 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
8
States / cities
Phoenix, Arizona • Laguna Hills, California • North Hollywood, California + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 17, 2025 · Synced Oct 22, 2026, 5:25 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

ISOVUE Comparative Trial

NCT07363759
View directory record Official record
Conditions
Lumbar Degenerative Disease, Lumbar Degenerative Disc Disease, Degenerative Spine
Interventions
ISOVUE 300 Observation, ISOVUE 300 Feedback
Procedure
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 100 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 23, 2026 · Synced Oct 22, 2026, 5:25 AM EDT
Completed No phase listed Observational

Medial Branch Radiofrequency Ablation and Lumbar Multifidi

NCT03744260
View directory record Official record
Conditions
Spondylosis, Osteoarthritis
Interventions
Patients undergo ultrasound and lumbar MRI
Diagnostic Test
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 10, 2020 · Synced Oct 22, 2026, 5:25 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Effects of Thoracic Spine Mobilizations in Individuals With Neck Pain.

NCT02356380
View directory record Official record
Conditions
Neck Pain
Interventions
Mobilization Type
Other
Lead sponsor
Chatham University
Other
Eligibility
18 Years to 60 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 27, 2017 · Synced Oct 22, 2026, 5:25 AM EDT
Completed Not applicable Interventional

Intelligent Spine Interface, Clinical (ISI-C)

NCT04302259
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Intelligent Spine Interface
Device
Lead sponsor
Rhode Island Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 14, 2026 · Synced Oct 22, 2026, 5:25 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Neurological Surgery & Affiliated Services De-Identified Clinical Outcomes Database

NCT00593411
View directory record Official record
Conditions
Central Nervous System Disorder, Spine Disease, Peripheral Nerve Disorder
Interventions
Not listed
Lead sponsor
University of California, Irvine
Other
Eligibility
7 Years and older
Enrollment
732 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2012
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Mar 29, 2021 · Synced Oct 22, 2026, 5:25 AM EDT
Recruiting Not applicable Interventional

Vertebroplasty With Radiation Therapy for Spine Metastatic Cancer Patients With Indeterminate Lesion (SINS Criteria)

NCT05178472
View directory record Official record
Conditions
Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm, Metastatic Malignant Neoplasm in the Spine
Interventions
Immunotherapy, Stereotactic Radiosurgery, Vertebroplasty
Other · Radiation · Procedure
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 9, 2026 · Synced Oct 22, 2026, 5:25 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Tissue Collection for Understanding Intervertebral Disc Degeneration and Back Pain

NCT01633034
View directory record Official record
Conditions
Intervertebral Disc Degeneration, Back Pain
Interventions
Not listed
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2025
U.S. locations
2
States / cities
Manhasset, New York • Manhattan, New York
Source: ClinicalTrials.gov public record
Updated Mar 20, 2024 · Synced Oct 22, 2026, 5:25 AM EDT
Terminated No phase listed Observational

Intraocular Pressure During Prone Spinal Surgery

NCT00176722
View directory record Official record
Conditions
Spine Surgery, Vision Impairment
Interventions
table tilt
Other
Lead sponsor
University of Medicine and Dentistry of New Jersey
Other
Eligibility
18 Years to 65 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
2
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 24, 2015 · Synced Oct 22, 2026, 5:25 AM EDT
Terminated Phase 1 Interventional

Beta-Tricalcium Phosphate Bone Graft in Treating Patients Undergoing Surgery For Metastatic Spine Cancer

NCT01407341
View directory record Official record
Conditions
Adult Spinal Cord Neoplasm, Spinal Bone Metastases, Spinal Cord Compression
Interventions
musculoskeletal complications management/prevention, bone graft, quality-of-life assessment, questionnaire administration
Procedure · Other
Lead sponsor
University of Southern California
Other
Eligibility
Not listed
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 6, 2014 · Synced Oct 22, 2026, 5:25 AM EDT
Completed Not applicable Interventional

Evaluate Initial Safety of the HemiBridge™ System in Guided Spinal Growth Treatment of Progressive Idiopathic Scoliosis

NCT01465295
View directory record Official record
Conditions
Scoliosis
Interventions
Mechanical hemiepiphysiodesis using the HemiBridge System
Device
Lead sponsor
SpineForm LLC
Industry
Eligibility
10 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
2
States / cities
Cincinnati, Ohio • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 5, 2018 · Synced Oct 22, 2026, 5:25 AM EDT