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ClinicalTrials.gov public records Last synced Oct 21, 2026, 10:32 AM EDT

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Showing 97–120 of 510 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Spine Condition Clear all
Terminated No phase listed Observational

PMCF Study to Evaluate the VERTICALE® Cervical System in Spine Surgery According to Its Intended Use.

NCT05489822
View directory record Official record
Conditions
Degenerative Disc Disease (DDD), Instabilities, Trauma, Deformity
Interventions
VERTICALE® Cervical System
Device
Lead sponsor
Silony Medical GmbH
Industry
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Oct 21, 2026, 10:32 AM EDT
Completed Not applicable Interventional

Cutaneous Administration of Local Anesthetic for Spine Injection Procedures

NCT00756301
View directory record Official record
Conditions
Spinal Diseases
Interventions
Lidocaine local anesthesia- Alternative
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated Jun 6, 2012 · Synced Oct 21, 2026, 10:32 AM EDT
Completed Not applicable Interventional

Epsilon-Aminocaproaic Acid to Reduce the Need for Blood Transfusions During and Following Spine Surgery

NCT00320619
View directory record Official record
Conditions
Scoliosis, Kyphosis, Lordosis, Spondylitis, Spinal Stenosis
Interventions
Epsilon-Aminocaproic Acid (EACA), Placebo
Drug
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
18 Years and older
Enrollment
182 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2006
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 29, 2016 · Synced Oct 21, 2026, 10:32 AM EDT
Terminated Not applicable Interventional Results available

Conformal High Dose Intensity Modulated Radiation Therapy for Disease to Thoracic and Lumbar Spine

NCT01654068
View directory record Official record
Conditions
Vertebral Metastasis
Interventions
Conformal High Dose Intensity Modulated Radiation Therapy
Radiation
Lead sponsor
Ronald McGarry
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2016
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Apr 19, 2019 · Synced Oct 21, 2026, 10:32 AM EDT
Completed Phase 1 Interventional

Comparison of the Effectiveness of Mobilization and Manipulation of the Thoracic Spine in Patients With Mechanical Neck Pain

NCT00128869
View directory record Official record
Conditions
Neck Pain
Interventions
spine mobilizations, spine manipulations
Procedure
Lead sponsor
Newton-Wellesley Hospital
Other
Eligibility
18 Years to 60 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
4
States / cities
San Diego, California • Colorado Springs, Colorado • Newton, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated May 13, 2008 · Synced Oct 21, 2026, 10:32 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Measuring Reliability of Spine Mobilization in Low Back Pain

NCT07582705
View directory record Official record
Conditions
Low Back Pain, Low Back Ache, Low Back Pain, Mechanical, Low Back Pain, Posterior Compartment, Low Back Pain, Postural, Low Back Pain, Recurrent, Low Backache, Lower Back Pain, Lower Back Pain Chronic, Mechanical Low Back Pain, Postural Low Back Pain, Recurrent Low Back Pain
Interventions
Spinal mobilization
Procedure
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years to 70 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Oct 21, 2026, 10:32 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Cognitive Dysfunction in Hypertensive Patients Having Spine Surgery

NCT01140854
View directory record Official record
Conditions
Hypertension
Interventions
Lumbar spine surgery, Neurologic/neuropsychometric examinations
Procedure · Other
Lead sponsor
Columbia University
Other
Eligibility
60 Years to 90 Years
Enrollment
179 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 4, 2015 · Synced Oct 21, 2026, 10:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Driving After Cervical Spine Surgery

NCT02782923
View directory record Official record
Conditions
Cervical Disc Disease
Interventions
STISIM driving simulator
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 80 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 30, 2020 · Synced Oct 21, 2026, 10:32 AM EDT
Terminated Not applicable Interventional Results available

AccuLIF® PROSPECTIVE PATIENT OUTCOMES STUDY

NCT02704689
View directory record Official record
Conditions
Degenerative Disc Disease, Spondylolisthesis, Grade 1, Retrolisthesis
Interventions
AccuLIF expandable TLIF cage
Device
Lead sponsor
VB Spine, LLC
Industry
Eligibility
18 Years to 70 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 24, 2018 · Synced Oct 21, 2026, 10:32 AM EDT
Terminated Not applicable Interventional Results available

Human Amniotic Tissue-derived Allograft, NuCel, in Posteriolateral Lumbar Fusions for Degenerative Disc Disease

NCT02070484
View directory record Official record
Conditions
Lumbar Degenerative Disc Disease, Spinal Stenosis, Spondylolisthesis, Spondylosis, Intervertebral Disk Displacement, Intervertebral Disk Degeneration, Spinal Diseases, Bone Diseases, Musculoskeletal Diseases, Spondylolysis
Interventions
NuCel, Demineralized Bone Matrix
Biological
Lead sponsor
OhioHealth
Other
Eligibility
18 Years to 75 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
2
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 28, 2018 · Synced Oct 21, 2026, 10:32 AM EDT
Completed Not applicable Interventional

Comparing Mesenchymal Stem Cell Counts in Unilateral vs. Bilateral Posterior Superior Iliac Spine Bone Marrow Aspiration

NCT03014037
View directory record Official record
Conditions
Osteoarthritis
Interventions
Unilateral Bone Marrow Procurement, Bilateral Bone Marrow Procurement
Procedure
Lead sponsor
Emory University
Other
Eligibility
18 Years to 70 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Dec 14, 2021 · Synced Oct 21, 2026, 10:32 AM EDT
Terminated Phase 2 Interventional

A Study Comparing the Safety and Effectiveness of Cartilage Cell Injected Into the Lumbar Disc as Compared to a Placebo

NCT01771471
View directory record Official record
Conditions
Degenerative Disc Disease
Interventions
NuQu, Placebo
Biological · Other
Lead sponsor
ISTO Technologies, Inc.
Industry
Eligibility
21 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2020
U.S. locations
10
States / cities
Birmingham, Alabama • San Francisco, California • Santa Monica, California + 7 more
Source: ClinicalTrials.gov public record
Updated Aug 31, 2017 · Synced Oct 21, 2026, 10:32 AM EDT
Completed No phase listed Observational

Intrathecal Morphine on Transcranial Electric Motor-Evoked Potentials

NCT00596609
View directory record Official record
Conditions
Trauma, Nervous System
Interventions
Intrathecal Morphine
Drug
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
11 Years to 18 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 16, 2009 · Synced Oct 21, 2026, 10:32 AM EDT
Completed Phase 4 Interventional

Spine Patient Outcomes Research Trial (SPORT): Degenerative Spondylolisthesis With Spinal Stenosis

NCT00000409
View directory record Official record
Conditions
Spondylolisthesis, Spinal Stenosis, Low Back Pain
Interventions
Decompressive laminectomy, Non-surgical treatments, Fusion--Instrumented, Fusion-Non-instrumented
Procedure · Other
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
304 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2015
U.S. locations
13
States / cities
Oakland, California • San Francisco, California • Decatur, Georgia + 9 more
Source: ClinicalTrials.gov public record
Updated Aug 4, 2015 · Synced Oct 21, 2026, 10:32 AM EDT
Completed Not applicable Interventional

Impact of DuoTherm Compared to TENS on Pain and Disability With Acute and Chronic Low Back Pain

NCT04494698
View directory record Official record
Conditions
Acute Low-back Pain, Chronic Low-back Pain, Pain, Intractable
Interventions
Duotherm VibraCool Back Device, TENS 8-channel unit
Device
Lead sponsor
MMJ Labs LLC
Industry
Eligibility
18 Years to 90 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
2
States / cities
Landover, Maryland • Fairfax, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 18, 2025 · Synced Oct 21, 2026, 10:32 AM EDT
Withdrawn Phase 3 Interventional Accepts healthy volunteers

Perioperative Bleeding and Aspirin Use in Spine Surgery

NCT02807441
View directory record Official record
Conditions
Hemorrhage, Thrombosis
Interventions
Acetylsalicylic acid
Drug
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 11, 2021 · Synced Oct 21, 2026, 10:32 AM EDT
Active, not recruiting Not applicable Interventional

Non-pharmacological Treatment for Pain After Spine Surgery

NCT04770480
View directory record Official record
Conditions
Low Back Pain, Chronic Pain, Surgery, Back Pain, Low, Back Pain Lower Back Chronic
Interventions
Standard Care (SC), Enriched Pain Management Pathway (EPM)
Behavioral
Lead sponsor
Dan Rhon
Federal
Eligibility
18 Years to 75 Years
Enrollment
267 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
3
States / cities
Honolulu, Hawaii • San Antonio, Texas • Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Oct 21, 2026, 10:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Resilience Skills Self-Management for Chronic Pain.

NCT03304613
View directory record Official record
Conditions
Chronic Spine Pain, Fibromyalgia
Interventions
Web-based Cognitive Behavioral Therapy (e-CBT) Self-Management, Promoting Resilience through Innovative Self-Management
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
35 Years to 65 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 18, 2023 · Synced Oct 21, 2026, 10:32 AM EDT
Enrolling by invitation No phase listed Observational

Lumbar Interbody Implant Study

NCT04418830
View directory record Official record
Conditions
Degenerative Disc Disease, Degenerative Spondylolisthesis, Degenerative Scoliosis, Spinal Stenosis, Sagittal Deformity
Interventions
Not listed
Lead sponsor
NuVasive
Industry
Eligibility
18 Years and older
Enrollment
1,050 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
16
States / cities
La Jolla, California • Los Alamitos, California • Merced, California + 13 more
Source: ClinicalTrials.gov public record
Updated Dec 22, 2025 · Synced Oct 21, 2026, 10:32 AM EDT
Completed Phase 3 Interventional Results available

The Kiva® System as a Vertebral Augmentation Treatment

NCT01123512
View directory record Official record
Conditions
Spinal Fractures, Fractures, Compression, Back Injuries
Interventions
Vertebral augmentation
Device
Lead sponsor
Benvenue Medical, Inc.
Industry
Eligibility
50 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
15
States / cities
Encinitas, California • Mountain View, California • Sacramento, California + 12 more
Source: ClinicalTrials.gov public record
Updated Oct 9, 2014 · Synced Oct 21, 2026, 10:32 AM EDT
Completed No phase listed Observational

Development of the MDASI-Spine Tumor Module

NCT00430872
View directory record Official record
Conditions
Spinal Cord Tumor
Interventions
Survey
Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 1, 2012 · Synced Oct 21, 2026, 10:32 AM EDT
Terminated Not applicable Interventional

A Prospective Study of NuCel® in Cervical Spine Fusion

NCT02381067
View directory record Official record
Conditions
Spondylosis, Spinal Stenosis, Spondylolisthesis, Intervertebral Disc Disease, Intervertebral Disc Degeneration
Interventions
NuCel with Allograft Bone
Other
Lead sponsor
NuTech Medical, Inc
Industry
Eligibility
21 Years and older
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Marietta, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 18, 2020 · Synced Oct 21, 2026, 10:32 AM EDT
Withdrawn No phase listed Observational

Diffusion Tensor Imaging to Assess the Functional Outcomes of Adults With Cervical Spinal Cord Injuries

NCT01712698
View directory record Official record
Conditions
Cervical Spinal Cord Injury
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 3, 2018 · Synced Oct 21, 2026, 10:32 AM EDT